6,537 results match your criteria provide "saturation"

The Effects of Blackcurrant and Caffeine Combinations on Performance and Physiology During Repeated High-Intensity Cycling.

Int J Sport Nutr Exerc Metab 2022 Aug 17:1-6. Epub 2022 Aug 17.

Faculty of Medical & Health Science, The University of Auckland, Auckland,New Zealand.

Blackcurrant juices and extracts containing anthocyanin may provide ergogenic benefits to sports performance. However, there are no studies examining the effects of coingestion of blackcurrant and caffeine. This investigation examined the effects of acute supplementation with a proprietary blackcurrant beverage administered in isolation or in combination with caffeine on repeated high-intensity cycling. Read More

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Evaluating Visual Photoplethysmography Method.

Cureus 2022 Jul 14;14(7):e26871. Epub 2022 Jul 14.

AI Research, Vastmindz Limited, London, GBR.

Regular monitoring of common physiological signs, including heart rate, blood pressure, and oxygen saturation, can be an effective way to either prevent or detect many kinds of chronic conditions. In particular, cardiovascular diseases (CVDs) are a worldwide concern. According to the World Health Organization, 32% of all deaths worldwide are from CVDs. Read More

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Opioid antagonism in humans: a primer on optimal dose and timing for central mu-opioid receptor blockade.

Neuropsychopharmacology 2022 Aug 17. Epub 2022 Aug 17.

Department of Diagnostic Physics, Oslo University Hospital, Oslo, Norway.

Non-human animal studies outline precise mechanisms of central mu-opioid regulation of pain, stress, affiliation and reward processing. In humans, pharmacological blockade with non-selective opioid antagonists such as naloxone and naltrexone is typically used to assess involvement of the mu-opioid system in such processing. However, robust estimates of the opioid receptor blockade achieved by opioid antagonists are missing. Read More

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Application of XGBoost model for in-situ water saturation determination in Canadian oil-sands by LF-NMR and density data.

Sci Rep 2022 Aug 17;12(1):13984. Epub 2022 Aug 17.

Centre for Petroleum Science and Engineering, Skolkovo Institute of Science and Technology, Sikorsky Street 11, Moscow, Russian Federation, 121205.

Water saturation determination is among the most challenging tasks in petrophysical well-logging, which directly impacts the decision-making process in hydrocarbon exploration and production. Low-field nuclear magnetic resonance (LF-NMR) measurements can provide reliable evaluation. However, quantification of oil and water volumes is problematic when their NMR signals are not distinct. Read More

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Critical appraisal of serum urate targets in the management of gout.

Nat Rev Rheumatol 2022 Aug 16. Epub 2022 Aug 16.

Faculty of Medicine and Health Sciences, University of Auckland, Auckland, New Zealand.

Gout management involves two broad aspects: treatment of gout flares to provide rapid symptomatic relief and long-term urate-lowering therapy to lower serum urate sufficiently to prevent gout flares from occurring. All of the major rheumatology societies recommend a target serum urate of <5 mg/dl (<0.30 mmol/l) or <6 mg/dl (<0. Read More

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Shedding light on the performance of magnetically recoverable TiO/FeO/rGO-5 photocatalyst. Degradation of S-metolachlor as case study.

Chemosphere 2022 Aug 10;307(Pt 3):135991. Epub 2022 Aug 10.

Departamento de Ingenierías Química y Biomolecular, Universidad de Cantabria, Avda. Los Castros, s/n, 39005, Santander, Spain. Electronic address:

Recalcitrant contaminants are not usually removed in conventional wastewater treatment plants. Therefore, they are transferred to the water resources that receive treated wastewaters and their presence can cause health and environmental issues. Herbicides are among these compounds. Read More

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Factors that influence uptake of routine postnatal care: Findings on women's perspectives from a qualitative evidence synthesis.

PLoS One 2022 12;17(8):e0270264. Epub 2022 Aug 12.

Department of Reproductive Health and Research, World Health Organization, Genève, Switzerland.

Background: Effective postnatal care is important for optimal care of women and newborns-to promote health and wellbeing, identify and treat clinical and psychosocial concerns, and to provide support for families. Yet uptake of formal postnatal care services is low and inequitable in many countries. As part of a larger study examining the views of women, partners, and families requiring both routine and specialised care, we analysed a subset of data on the views and experiences of women related to routine postnatal care. Read More

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Neglected Comorbidity of Chronic Heart Failure: Iron Deficiency.

Nutrients 2022 Aug 5;14(15). Epub 2022 Aug 5.

Inflammation Research Center CRI, INSERM UMRs 1149, Université de Paris, 75018 Paris, France.

Iron deficiency is a significant comorbidity of heart failure (HF), defined as the inability of the myocardium to provide sufficient blood flow. However, iron deficiency remains insufficiently detected. Iron-deficiency anemia, defined as a decrease in hemoglobin caused by iron deficiency, is a late consequence of iron deficiency, and the symptoms of iron deficiency, which are not specific, are often confused with those of HF or comorbidities. Read More

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Causes of futile care from the perspective of intensive care unit nurses (I.C.U): qualitative content analysis.

BMC Nurs 2022 Aug 12;21(1):225. Epub 2022 Aug 12.

Department of Operating Room, School of Paramedical Sciences, Birjand University of Medical Sciences, Birjand, Iran.

Background: Medical care that has therapeutic effects without significant benefits for the patient is called futile care. Intensive Care Units are the most important units in which nurses provide futile care. This study aimed to explain the causes of futile care from the perspective of nurses working in Intensive Care Units are. Read More

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Seven-day in vivo testing of a novel, low-resistance, pumpless pediatric artificial lung for long-term support.

J Pediatr Surg 2022 Jul 13. Epub 2022 Jul 13.

Department of Surgery, Extracorporeal Life Support Laboratory, Michigan Medicine, B560 MSRB II/SPC 5686, 1150 W. Medical Center Drive, Ann Arbor, MI 48109, USA; Department of Surgery, Section of Pediatric Surgery, Michigan Medicine, Ann Arbor, MI, USA.

Introduction: For children with end-stage lung disease that cannot wean from extracorporeal life support (ECLS), a wearable artificial lung would permit extubation and provide a bridge to recovery or transplantation. We evaluate the function of the novel Pediatric MLung-a low-resistance, pumpless artificial lung developed specifically for children-in healthy animal subjects.

Methods: Adolescent "mini sheep" weighing 12-20 kg underwent left thoracotomy, cannulation of the main pulmonary artery (PA; inflow) and left atrium (outflow), and connection to the MLung. Read More

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Tremor, finger and hand dexterity and force steadiness, do not change after mental fatigue in healthy humans.

PLoS One 2022 10;17(8):e0272033. Epub 2022 Aug 10.

Department of Movement, Human and Health Sciences, University of Rome Foro Italico, Rome, Italy.

The effects of mental fatigue have been studied in relation to specific percentages of maximal aerobic or anaerobic efforts, maximal voluntary contractions or the performance of sport specific skills. However, its effects on tremor, dexterity and force steadiness have been only marginally explored. The present work aimed at filling this gap. Read More

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Time resolved DCE-MRI of the kidneys: Evaluation of the renal vasculatures and tumors using F-DISCO with and without compressed sensing in normal and wide-bore 3T systems.

Medicine (Baltimore) 2022 Aug;101(31):e29971

Global MR Applications and Workflow, GE Healthcare Japan, Hino, Tokyo, Japan.

Dynamic contrast-enhanced MR imaging (DCE-MRI) has been widely used for the evaluation of renal arteries. This method is also useful for tumor and renal parenchyma characterization. The very fast MRI may provide stable and precise information regarding vasculature and soft tissues. Read More

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Accuracy of Oxygen Saturation Measurements in Patients with Obesity Undergoing Bariatric Surgery.

Obes Surg 2022 Aug 9. Epub 2022 Aug 9.

Department of Anesthesiology, The First Affiliated Hospital, Jinan University, No. 613, Huangpu Avenue West, Guangzhou, 510632, Guangdong, China.

Background: We aimed to determine the magnitude, direction, and influencing factors of the concordance between arterial oxygen saturation (SaO) and peripheral capillary oxygen saturation (SpO) in patients with obesity undergoing bariatric surgery, supporting the measurement of SaO and SpO in key populations.

Methods: Patients with obesity undergoing bariatric surgery from 2017 to 2020 were included. Preoperative SpO and SaO were collected. Read More

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Prevention and treatment of delirium in intensive care: Hermeneutics of experiences of the nursing team.

Enferm Intensiva (Engl Ed) 2022 Aug 6. Epub 2022 Aug 6.

Programa de Enfermería, Universidad Surcolombiana, Neiva, Huila, Colombia.

Objective: To understand the experiences in nursing care in the prevention and treatment of delirium in people hospitalized in intensive care units.

Methodology: Hermeneutic phenomenological qualitative study. The selection of participants was by intentional sampling: seven nursing assistants and eight nurses. Read More

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Parental perspectives on the use of silver diamine fluoride therapy to arrest early childhood caries in kindergarten outreach dental services: A qualitative study.

J Dent 2022 Aug 6;125:104250. Epub 2022 Aug 6.

Department of Stomatology, School of Medicine, Xiamen University, Xiamen, China; Faculty of Dentistry, The University of Hong Kong, Hong Kong, China. Electronic address:

Objectives: This study aimed to explore parental perspectives on an outreach dental service and silver diamine fluoride (SDF) therapy to arrest and prevent early childhood caries.

Methods: This qualitative study collaborated with an outreach service offering SDF therapy to kindergarten children and oral health education to the children's parents. The study was conducted in 2018 using purposive sampling of participating parents from selected kindergartens in Hong Kong until data saturation was reached. Read More

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Nurse's experience in giving nursing care to Covid-19 patients.

Enferm Clin 2022 Aug 2;32:S50-S53. Epub 2022 Aug 2.

Faculty of Health, Universitas Aufa Royhan, Padangsidimpuan, Indonesia.

Objective: The objective was to describe Nurse's experience in giving nursing care to covid-19 patients.

Method: Phenomenology design was used in this study. Participants in this study were nurses who provided nursing care for COVID-19 patients. Read More

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Nurses experience of caring for patients with COVID-19: A phenomenological study.

Front Psychiatry 2022 19;13:922410. Epub 2022 Jul 19.

Susan Wakil School of Nursing and Midwifery, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.

Introduction: COVID-19 has impacted all dimensions of life and imposed serious threat on humankind.

Background: In Jordan, understanding how nurses experienced providing care for patients with COVID-19 offers a framework of knowledge about similar situations within the context of Arabic culture.

Aim: To explore nurses' experience with providing hands-on care to patients with active COVID-19 infection in an Arabic society. Read More

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Breath-holding physiology, radiological severity and adverse outcomes in COVID-19 patients: A prospective validation study.

Respirology 2022 Aug 7. Epub 2022 Aug 7.

Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham & Women's Hospital & Harvard Medical School, Boston, Massachusetts, USA.

Background And Objective: COVID-19 remains a major cause of respiratory failure, and means to identify future deterioration is needed. We recently developed a prediction score based on breath-holding manoeuvres (desaturation and maximal duration) to predict incident adverse COVID-19 outcomes. Here we prospectively validated our breath-holding prediction score in COVID-19 patients, and assessed associations with radiological scores of pulmonary involvement. Read More

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Supramolecular Activation of S by Cucurbiturils in Water and Mechanism of Reduction to HS by Thiols: Insights into Biological Sulfane Sulfur Trafficking.

J Am Chem Soc 2022 Aug 5. Epub 2022 Aug 5.

Department of Chemistry and Biochemistry, Materials Science Institute, Knight Campus for Accelerating Scientific Impact, and Institute of Molecular Biology, University of Oregon, Eugene, Oregon 97403-12532, United States.

Reactive sulfur species (RSS) play critical roles in diverse chemical environments. Molecules containing sulfane sulfur (S) have emerged as key species involved in cellular redox buffering as well as RSS generation, translocation, and action. Using cucurbit[7]uril (CB[7]) as a model hydrophobic host, we demonstrate here that S can be encapsulated to form a 1:1 host guest complex, which was confirmed by solution state experiments, mass spectrometry, and X-ray crystallography. Read More

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Creeping disaster along the U.S. coastline: Understanding exposure to sea level rise and hurricanes through historical development.

PLoS One 2022 3;17(8):e0269741. Epub 2022 Aug 3.

Earth Lab, Cooperative Institute for Research in Environmental Sciences, University of Colorado Boulder, Boulder, Colorado, United States of America.

Current estimates of U.S. property at risk of coastal hazards and sea level rise (SLR) are staggering-evaluated at over a trillion U. Read More

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The effect of arginine on inhibiting amyloid fibril derived from β-casein and the binding studies with multi-spectroscopic techniques.

Spectrochim Acta A Mol Biomol Spectrosc 2022 Jul 26;282:121681. Epub 2022 Jul 26.

Department of Natural Product Chemistry, Pharmacy College, Jilin University, Changchun, PR China. Electronic address:

In general, β-casein is a stable molecular chaperone. However, the fact that amyloid fibrils derived from β-casein has been reported in some cases, which were usually associated with some malignant breast diseases. As an important amino acid, arginine not only exhibits the significance in casein synthesis in mammary gland, but also has great potentiality in inhibiting the amyloid fibril formation. Read More

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The Quantitative Associations Between Near Infrared Spectroscopic Cerebrovascular Metrics and Cerebral Blood Flow: A Scoping Review of the Human and Animal Literature.

Front Physiol 2022 15;13:934731. Epub 2022 Jul 15.

Department of Human Anatomy and Cell Science, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.

Cerebral blood flow (CBF) is an important physiologic parameter that is vital for proper cerebral function and recovery. Current widely accepted methods of measuring CBF are cumbersome, invasive, or have poor spatial or temporal resolution. Near infrared spectroscopy (NIRS) based measures of cerebrovascular physiology may provide a means of non-invasively, topographically, and continuously measuring CBF. Read More

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Stylasterid corals build aragonite skeletons in undersaturated water despite low pH at the site of calcification.

Sci Rep 2022 Jul 30;12(1):13105. Epub 2022 Jul 30.

School of Earth Sci. Univ. of Bristol, Queens Road, Bristol, BS8 1RJ, UK.

Anthropogenic carbon emissions are causing seawater pH to decline, yet the impact on marine calcifiers is uncertain. Scleractinian corals and coralline algae strongly elevate the pH of their calcifying fluid (CF) to promote calcification. Other organisms adopt less energetically demanding calcification approaches but restrict their habitat. Read More

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Quantifying cerebral blood arrival times using hypoxia-mediated arterial BOLD contrast.

Neuroimage 2022 Jul 27;261:119523. Epub 2022 Jul 27.

Joint Department of Medical Imaging and the Functional Neuroimaging Lab, University Health Network, Toronto, ON, Canada.

Cerebral blood arrival and tissue transit times are sensitive measures of the efficiency of tissue perfusion and can provide clinically meaningful information on collateral blood flow status. We exploit the arterial blood oxygen level dependent (BOLD) signal contrast established by precisely decreasing, and then increasing, arterial hemoglobin saturation using respiratory re-oxygenation challenges to quantify arterial blood arrival times throughout the brain. We term this approach the Step Hemoglobin re-Oxygenation Contrast Stimulus (SHOCS). Read More

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Longitudinal examination of perfusion and angiogenesis markers in primary colorectal tumors shows distinct signatures for metronomic and maximum-tolerated dose strategies.

Neoplasia 2022 Jul 25;32:100825. Epub 2022 Jul 25.

Department of Biomedical Engineering, University of Arkansas, Fayetteville, AR, USA. Electronic address:

Metronomic chemotherapy (MET) has been developed to address the shortcomings of maximum-tolerated chemotherapy (MTD) in regard to toxicity and development of resistance mechanisms in the tumor. In colorectal cancer (CRC), MET is a promising novel strategy to treat locally advanced malignancies when used as neoadjuvant chemotherapy (NAC). However, so far there are no preclinical studies to assess the impact of MET NAC in CRC to assess the benefits and challenges of this approach. Read More

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Sleep Apnea Detection Using Multi-Error-Reduction Classification System with Multiple Bio-Signals.

Sensors (Basel) 2022 Jul 25;22(15). Epub 2022 Jul 25.

School of Electrical and Data Engineering, Faculty of Engineering and Information Technology (FEIT), University of Technology Sydney (UTS), Ultimo, NSW 2007, Australia.

Introduction: Obstructive sleep apnea (OSA) can cause serious health problems such as hypertension or cardiovascular disease. The manual detection of apnea is a time-consuming task, and automatic diagnosis is much more desirable. The contribution of this work is to detect OSA using a multi-error-reduction (MER) classification system with multi-domain features from bio-signals. Read More

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Adoption of Telemedicine in a Rural US Cancer Center Amid the COVID-19 Pandemic: Qualitative Study.

JMIR Cancer 2022 Aug 16;8(3):e33768. Epub 2022 Aug 16.

Department of Community and Family Medicine, Geisel School of Medicine at Dartmouth, Lebanon, NH, United States.

Background: The COVID-19 pandemic necessitated a rapid shift to telemedicine to minimize patient and provider exposure risks. While telemedicine has been used in a variety of primary and specialty care settings for many years, it has been slow to be adopted in oncology care. Health care provider and administrator perspectives on factors affecting telemedicine use in oncology settings are not well understood, and the conditions associated with the COVID-19 pandemic offered the opportunity to study the adoption of telemedicine and the resulting provider and staff perspectives on its use. Read More

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A Modified Yeast Two-Hybrid Platform Enables Dynamic Control of Expression Intensities to Unmask Properties of Protein-Protein Interactions.

ACS Synth Biol 2022 Aug 27;11(8):2589-2598. Epub 2022 Jul 27.

The Robert H. Smith Institute of Plant Sciences and Genetics in Agriculture, The Hebrew University of Jerusalem, Rehovot 7610000, Israel.

The yeast two-hybrid (Y2H) assay is widely used for protein-protein interaction characterization due to its simplicity and accessibility. However, it may mask changes in affinity caused by mutations or ligand activation due to signal saturation. To overcome this drawback, we modified the Y2H system to have tunable protein expression by introducing a fluorescent reporter and a pair of synthetic inducible transcription factors to regulate the expression of interacting components. Read More

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Medical students' perception towards mental health recovery: a descriptive qualitative study.

Med Educ Online 2022 Dec;27(1):2106610

Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

The conceptualisation of recovery in mental healthcare, for which two definitions ('clinical' and 'personal') prevail, remains inconclusive. In most curricula of medical education, undergraduates are taught straightforward concepts of clinical recovery, which result in their perfunctory and rudimentary understanding. A qualitative descriptive approach was adopted to explore medical undergraduates' perceptions of recovery for people with mental health conditions. Read More

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December 2022

A Narrative Review of Telemedicine in Latin America during the COVID-19 Pandemic.

Healthcare (Basel) 2022 Jul 22;10(8). Epub 2022 Jul 22.

School of Health, Universidad de Especialidades Espíritu Santo, Samborondón, Guayas 0901952, Ecuador.

Background: The COVID-19 pandemic greatly impacted traditional health structures, posing new challenges in an unprecedented health crisis. Telemedicine services were implemented in countries with robust digital platforms to reduce hospital attendance while continuing to provide medical care. This study aims to determine how telemedicine services have been used as a tool to ensure the right to health in Latin America during the pandemic. Read More

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