23,475 results match your criteria protein-coding genes


An enhancer screen identifies new suppressors of small-RNA-mediated epigenetic gene silencing.

PLoS Genet 2021 Jun 22;17(6):e1009645. Epub 2021 Jun 22.

Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.

Small non-protein coding RNAs are involved in pathways that control the genome at the level of chromatin. In Schizosaccharomyces pombe, small interfering RNAs (siRNAs) are required for the faithful propagation of heterochromatin that is found at peri-centromeric repeats. In contrast to repetitive DNA, protein-coding genes are refractory to siRNA-mediated heterochromatin formation, unless siRNAs are expressed in mutant cells. Read More

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In silico analysis of promoter region and regulatory elements of mitogenome co-expressed trn gene clusters encoding for bio-pesticide in entomopathogenic fungus, Metarhizium anisopliae: strain ME1.

J Genet Eng Biotechnol 2021 Jun 22;19(1):94. Epub 2021 Jun 22.

Department of Applied Biology, School of Applied Natural Science, Adama Science and Technology University, P.O. Box 1888, Adama, Ethiopia.

Background: Pest control strategies almost entirely rely on chemical insecticides, which cause environmental problems such as biosphere deterioration and emergence of resistant pests. Bio-pesticide is an alternative approach, which uses organisms such as entomopathogenic fungi, Metarhizium anisopliae, to control pests. Screening such potential organism at a molecular level and understanding their gene regulation mechanism is an important approach to reduce emergence of pesticide resistance and worsening of the biosphere. Read More

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The Long Road to Understanding RNAPII Transcription Initiation and Related Syndromes.

Annu Rev Biochem 2021 Jun;90:193-219

Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS, INSERM, Université de Strasbourg, 67404 Illkirch CEDEX, Commune Urbaine de Strasbourg, France; email:

In eukaryotes, transcription of protein-coding genes requires the assembly at core promoters of a large preinitiation machinery containing RNA polymerase II (RNAPII) and general transcription factors (GTFs). Transcription is potentiated by regulatory elements called enhancers, which are recognized by specific DNA-binding transcription factors that recruit cofactors and convey, following chromatin remodeling, the activating cues to the preinitiation complex. This review summarizes nearly five decades of work on transcription initiation by describing the sequential recruitment of diverse molecular players including the GTFs, the Mediator complex, and DNA repair factors that support RNAPII to enable RNA synthesis. Read More

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Morphological and complete mitogenomic characterisation of the acanthocephalan Polymorphus minutus infecting the duck Anas platyrhynchos.

Folia Parasitol (Praha) 2021 Jun 1;68. Epub 2021 Jun 1.

State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.

Morphological characteristics of the acanthocephalan Polymorphus minutus (Goeze, 1782), which was collected from the duck Anas platyrhynchos Linnaeus in the Czech Republic, are described. The mitochondrial (mt) genome of P. minutus was sequenced, with a total length of 14,149 bp, comprising 36 genes including 12 protein coding genes (PCGs), 22 transfer RNA (tRNA) genes and two ribosomal RNA genes (rrnL and rrnS). Read More

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The complete mitochondrial genome of sp.1 (Teleostei, Platycephalidae) obtained by whole genome sequencing.

Mitochondrial DNA B Resour 2021 Jun 7;6(7):1941-1943. Epub 2021 Jun 7.

Fisheries College, Zhejiang Ocean University, Zhoushan, China.

In this study, we used next-generation sequencing to obtain the complete mitochondrial genome of sp.1. This mitochondrial genome, consisting of 16,552 base pairs (bp), contains 13 protein-coding genes, two ribosomal RNAs, 22 transfer RNAs, and two non-coding control regions (control region and origin of light-strand replication) as those found in other vertebrates. Read More

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Characterization and phylogenetic analysis of the complete chloroplast genome sequence of (Asteraceae), a rare and endangered wild plant species in China.

Mitochondrial DNA B Resour 2021 Jun 7;6(7):1934-1936. Epub 2021 Jun 7.

College of Life Sciences, Taizhou University, Jiaojiang, China.

(Asteraceae) is a rare wild plant species narrowly distributed in Zhejiang province, China. In our present study, we assembled its complete chloroplast genome using high-throughput sequencing data. The results indicated that the whole chloroplast genome of was 153,396 bp in length. Read More

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The first complete mitochondrial genome of (Gahan 1906) (Coleoptera: Cerambycidae: Cerambycinae) and its phylogeny.

Mitochondrial DNA B Resour 2021 Jun 7;6(7):1929-1931. Epub 2021 Jun 7.

College of Chemistry and Life Science, Zhejiang Normal University, Jinhua, PR China.

is a common species of Cerambycidae, reported from Vietnam, Nepal, Laos, Burma, and China. To date, no mitochondrial genomes of the genus have been reported. In this study, we sequenced and analyzed the first mitochondrial genome of to discuss its phylogenetic relationship within the subfamily Cerambycinae. Read More

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The complete plastid genome sequence of (Ericales: Ericaceae), a deciduous broad-leaved shrub endemic to East Asia.

Mitochondrial DNA B Resour 2021 Jun 7;6(7):1926-1928. Epub 2021 Jun 7.

Department of Biology Education, Chonnam National University, Gwangju, Republic of Korea.

We here sequenced the complete plastid genome (plastome) of (Ericaceae), a deciduous broad-leaved shrub endemic to East Asia. This species has considerable practical economic value. The plastome of is assembled as a single contig (187,213 bp). Read More

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Complete chloroplast genome of medicinal plant Wall. ex Roxb. (Sabiaceae).

Mitochondrial DNA B Resour 2021 Jun 7;6(7):1924-1925. Epub 2021 Jun 7.

College of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang, PR China.

Wall. ex Roxb., an evergreen climbing woody vine, is a Chinese herbal medicine commonly used by ethnic minorities in some areas of China. Read More

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Complete mitochondrial genomes of two marine monogonont rotifer strains.

Mitochondrial DNA B Resour 2021 Jun 7;6(7):1921-1923. Epub 2021 Jun 7.

Department of Biological Sciences, College of Science, Sungkyunkwan University, Suwon, South Korea.

The complete mitochondrial genomes of German strain were 10,721 bp (mitochondrial DNA I) and 12,274 bp (mitochondrial DNA II) in size, while the complete mitochondrial genomes of Australian strain were 10,889 bp (mitochondrial DNA I) and 12,443 bp (mitochondrial DNA II) in size. Of 12 protein-coding genes (PCGs), 99.6% of amino acid sequences were identical between the two strains. Read More

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The complete chloroplast genome of .

Mitochondrial DNA B Resour 2021 Jun 7;6(7):1919-1920. Epub 2021 Jun 7.

Forage Plant Research Center for Institute of Tropical and Subtropical Economic Crops, Yunnan Academy of Agricultural Sciences, Baoshan, Yunnan Province, China.

Here, we report the complete chloroplast genome of . The genome is 153,388 bp in size, which is comprised of a large single-copy (LSC) region of 84,724 bp, a small single-copy (SSC) region of 18,716 bp, and two inverted repeat (IR) regions of 24,974 bp. The overall GC content of the plastome was 38. Read More

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The complete chloroplast genome of P. C. Li (Leguminosae: Papilionoideae), an endemic species of China.

Mitochondrial DNA B Resour 2021 Jun 7;6(7):1917-1918. Epub 2021 Jun 7.

Lushan Botanical Garden, Chinese Academy of Sciences, Jiujiang, PR China.

The first complete plastid genome (plastome) of a small genus, (Ali) H. P. Tsui, was sequenced from P. Read More

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Complete mitochondrial DNA sequence of yellow-legged buttonquail ().

Mitochondrial DNA B Resour 2021 Jun 7;6(7):1914-1916. Epub 2021 Jun 7.

Forestry College, Guizhou University, Guiyang, China.

The Yellow-legged Buttonquail is a species of the genus , which belongs to the order Charadriiformes. It is distributed across almost all of China. The International Union for Conservation of Nature has assessed the bird's conservation status as 'Least Concern (LC). Read More

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The complete chloroplast genome of (Orchidaceae).

Mitochondrial DNA B Resour 2021 Jun 7;6(7):1897-1898. Epub 2021 Jun 7.

Guizhou Horticulture Institute, Guizhou Academy of Agricultural Sciences, Guiyang, China.

, a wild orchid species in the Orchid family (Orchidaceae), is considered highly valuable because of its long flowering period and beautiful plant shape. We sequenced the complete chloroplast genome of using the Illumina Hiseq platform (Illumina, San Diego, CA). The size of the chloroplast genome is 155,408 bp, with an average GC content of 36. Read More

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The complete chloroplast genome sequence of Maxim (Moraceae) from Guangzhou, China.

Mitochondrial DNA B Resour 2021 Jun 7;6(7):1895-1896. Epub 2021 Jun 7.

Guangdong Provincial Key Laboratory of Crops Genetics and Improvement, Crops Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, China.

Maxim is an economically valuable plant that is traditionally used in Chinese medicine. Here, we assembled the complete chloroplast (cp) genome of using Illumina high-throughput sequencing technology. The cp genome size is 160,606 bp, with 35. Read More

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The complete chloroplast genome sequence of W. W. Smith (Lauraceae) from Jiangxi Province, China.

Mitochondrial DNA B Resour 2021 Jun 7;6(7):1890-1892. Epub 2021 Jun 7.

Camphor Engineering Technology Research Center for National Forestry and Grassland Administration, Jiangxi Academy of Forestry, Nanchang, China.

W. W. Smith is an evergreen plant distributed in the Yangtze River Basin and the south regions of China. Read More

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The complete chloroplast genome of a Chinese medicinal plant, (Thunb.) Bremek. (Lamiales: Acanthaceae) from Nanjing, China.

Mitochondrial DNA B Resour 2021 Jun 7;6(7):1888-1889. Epub 2021 Jun 7.

School of Traditional Chinese Medicine, China Pharmaceutical University, Nanjing, China.

(Thunb.) Bremek. is a widely distributed medicinal plant species in China and Japan. Read More

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The complete mitogenome sequence of the hawk moth, subsp. (Lepidoptera: Sphingidae) from Zhejiang Province, China.

Mitochondrial DNA B Resour 2021 Jun 7;6(7):1880-1882. Epub 2021 Jun 7.

College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, Zhejiang, China.

The sphingid, subsp. is a common hawk moth distributed in southeast Asia and Australian regions. Although barcode analyses have been published, its complete mitogenome sequence has not been deciphered. Read More

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The complete chloroplast genome of Rehder (Hydrangeaceae).

Mitochondrial DNA B Resour 2021 Jun 7;6(7):1877-1879. Epub 2021 Jun 7.

School of Landscape Architecture and Horticulture Sciences, Southwest Forestry University, Kunming, China.

Rehder is a wild flowering shrub with high ornamental value. The complete chloroplast genome sequence of was characterized from Hiseq (Illumina Co., San Diego, CA) sequencing data. Read More

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The complete chloroplast genome of (Lauraceae).

Mitochondrial DNA B Resour 2021 Jun 7;6(7):1875-1876. Epub 2021 Jun 7.

School of Life Sciences, Nanjing University, Nanjing, China.

H. W. Li, is a member of the Lauraceae family, while its generic relationship has been long-term controversial. Read More

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The complete mitochondrial genomes of two Chinese endemic cave fishes, and (Cypriniformes: Cyprinidae).

Mitochondrial DNA B Resour 2021 Jun 7;6(7):1869-1870. Epub 2021 Jun 7.

Liuzhou Aquaculture Technology Extending Station, Liuzhou, China.

and were collected from a karst cave Libo County, southwest of China. The two species can be distinguished obviously by external morphological characteristics. In this study, the complete mitochondrial genome sequences of two species were assembled, and both sequences reflected gene organization typical for mitochondrial DNA of the genus comprising of 13 protein-coding genes (PCGs), 22 transfer RNA genes (tRNAs), 2 ribosomal RNA genes (rRNAs), and a large non-coding control region. Read More

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The first complete chloroplast genome of (Fabaceae) and its phylogenetic analysis.

Mitochondrial DNA B Resour 2021 Jun 7;6(7):1865-1866. Epub 2021 Jun 7.

College of Basic Medicine, Dali University, Dali, China.

DC. was a scandent shrub. In this study, we sequenced the complete chloroplast (cp) genome of to investigate its phylogenetic relationship in Fabaceae. Read More

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The complete chloroplast genome of (Fabaceae: Papilionoideae).

Mitochondrial DNA B Resour 2021 Jun 7;6(7):1860-1861. Epub 2021 Jun 7.

College of Life and Environment Sciences, Huangshan University, Huangshan, China.

The complete chloroplast genome of reported herein was a circular DNA molecule of 154,542 bp in length. The genome had a typical quadripartite structure, consisting of a pair of inverted repeats (IRa and IRb: 24,836 bp) separated by a large single-copy region (LSC: 67,996 bp) and a small single-copy region (SSC: 18,363 bp). The overall GC content of the genome was 35. Read More

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High-quality draft genome sequence data of six subsp. strains isolated from various Greek wheat sourdoughs.

Data Brief 2021 Aug 28;37:107172. Epub 2021 May 28.

Department of Dairy Research, Institute of Technology of Agricultural Products, Hellenic Agricultural Organization "DIMITRA", 3 Ethnikis Antistaseos St., 45221 Ioannina, Greece.

is a species found in a wide range of foods and other commodities. It can be used as starter or adjunct culture in fermented foods. Herein the annotated high-quality draft genome (scaffolds) of six subsp. Read More

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Construction and Analysis of the Dysregulated ceRNA Network and Identification of Risk Long Noncoding RNAs in Breast Cancer.

Front Genet 2021 4;12:664393. Epub 2021 Jun 4.

College of Artificial Intelligence and Big Data for Medical Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China.

Breast cancer (BRCA) is the second leading cause of cancer-related mortality in women worldwide. However, the molecular mechanism involved in the development of BRCA is not fully understood. In this study, based on the miRNA-mediated long non-coding RNA (lncRNA)-protein coding gene (PCG) relationship and lncRNA-PCG co-expression information, we constructed and analyzed a specific dysregulated lncRNA-PCG co-expression network in BRCA. Read More

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Phylogenomic Analyses of Species and Comparative Analyses Within Tribe Anemoneae (Ranunculaceae).

Front Plant Sci 2021 4;12:638580. Epub 2021 Jun 4.

Department of Life Sciences, Yeungnam University, Gyeongsan, South Korea.

is a small genus of Ranunculaceae with medicinal and horticultural value. We characterized nine complete chloroplast (cp) genomes of , which ranged from 159,549 to 161,081 bp in length and had a typical quadripartite structure with a large single-copy region (LSC; 80,270-81,249 bp), a small single-copy region (SSC; 17,029-17,838 bp), and two copies of inverted repeat (IR; 31,008-31,100 bp). The cp genomes of possess 76 protein-coding genes (PCGs), 29 tRNAs, and four rRNA genes. Read More

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Sequencing and Comparative Genomic Analysis of a Highly Metal-Tolerant P1 Provide Insights Into Its Metal Tolerance.

Front Microbiol 2021 4;12:663217. Epub 2021 Jun 4.

Hunan Agricultural Product Processing Institute, Hunan Academy of Agricultural Sciences, Changsha, China.

Heavy metal pollution is a global knotty problem and fungi hold promising potential for the remediation of wastewater containing heavy metals. Here, a new highly chromium-tolerance species, P1, is investigated. The genome of P1 was sequenced and assembled into 30 Mb genome size containing 10,955 predicted protein-coding genes with a GC content of 46. Read More

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Genome and Evolutionary Analysis of : A Microsporidian Parasite of Honey Bees.

Front Microbiol 2021 2;12:645353. Epub 2021 Jun 2.

US Department of Agriculture-Aricultural Research Service (USDA-ARS) Bee Research Laboratory, Beltsville, MD, United States.

Microsporidia comprise a phylum of single cell, intracellular parasites and represent the earliest diverging branch in the fungal kingdom. The microsporidian parasite primarily infects honey bee gut epithelial cells, leading to impaired memory, suppressed host immune responses and colony collapse under certain circumstances. As the genome of is challenging to assembly due to very high genetic diversity and repetitive region, the genome was re-sequenced using long reads. Read More

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The mitochondrial genome and phylogenetic characteristics of the Thick-billed Green-Pigeon, : the first sequence for the genus.

Zookeys 2021 2;1041:167-182. Epub 2021 Jun 2.

College of Biology and the Environment, Nanjing Forestry University, Nanjing 210037, China Nanjing Forestry University Nanjing China.

Members of the genus (Columbidae) are widely distributed in southern Asia and the Indo-Malayan Region but their relationships are poorly understood. Better knowledge of the systematic status of this genus may help studies of historical biogeography and taxonomy. The complete mitochondrial genome of was characterized, a first for the genus. Read More

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Genome assembly and annotation of Photorhabdus heterorhabditis strain ETL reveals genetic features involved in pathogenicity with its associated entomopathogenic nematode and anti-host effectors with biocontrol potential applications.

Gene 2021 Jun 17:145780. Epub 2021 Jun 17.

Department of Biotechnology and Food Technology, Faculty of Science, University of Johannesburg, Doornfontein Campus, 2028, South Africa. Electronic address:

The genome sequences of entomopathogenic nematode (EPN) bacteria and their functional analyses can lead to the genetic engineering of the bacteria for use as biocontrol agents. The bacterial symbiont Photorhabdus heterorhabditis strain ETL isolated from an insect pathogenic nematode, Heterorhabditis zealandica strain ETL, collected in the northernmost region of South Africa was studied to reveal information that can be useful in the design of improvement strategies for both effective and liquid production method of EPN-based pesticides. The strain ETL genome was found closely related to the type strain genome of P. Read More

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