25,827 results match your criteria protein-coding gene


Phenotypic spectrum and mechanism analysis of Schaff Yang syndrome: A case report on new mutation of MAGEL2 gene.

Medicine (Baltimore) 2021 Jun;100(24):e26309

Department of Endocrinology, Shandong Provincial Hospital affiliated to Shandong First Medical University.

Rationale: The Schaaf-Yang syndrome (SYS) is an autosomal dominant multi-system genetic disease caused by melanoma antigen L2 (MAGEL2) gene mutations imprinted by mothers and expressed by fathers on the 15q11-15q13 chromosomes in the critical region of Prader-Willi. MAGEL2 is a single exon gene and one of the protein-coding genes of the Prader-Willi domain. MAGEL2 is a matrilineal imprinted gene (i. Read More

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The complete chloroplast genome of .

Mitochondrial DNA B Resour 2021 Jun 4;6(7):1855-1856. Epub 2021 Jun 4.

Environment and Plant Protection Institute, Chinese Academy of Tropical Agricultural Sciences, Haikou, PR China.

is one of the Agave cultivars for sisal fiber production around the tropical areas of the world. In the present study, we successfully sequenced and assembled its chloroplast genome. The full size of the genome is 157,268 bp with a GC content at 37. Read More

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Characterization of the complete chloroplast genome of L. var. with phylogenetic analysis.

Mitochondrial DNA B Resour 2021 Jun 3;6(7):1852-1854. Epub 2021 Jun 3.

Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Sichuan Engineering and Technology Research Center of Coarse Cereal Industralization, School of Food and Biological Engineering, Chengdu University, Chengdu, P. R. China.

In the present study, the complete chloroplast genome of L. var. was sequenced, assembled and compared with closely related species. Read More

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The complete mitochondrial genome and phylogenetic analysis of (Coscinodiscophyceae, Bacillariophyta).

Mitochondrial DNA B Resour 2021 Jun 3;6(7):1849-1851. Epub 2021 Jun 3.

CAS Key Laboratory of Marine Ecology and Environmental Sciences, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China.

is a species-rich genus with about 400 species described, many of which are harmful algal bloom species with significant negative ecological impact. Despite of their importance in primary production and as harmful algal bloom species, genome data for species in this genus is limited. No mitochondrial genome (mtDNA) of any species in this genus has been reported. Read More

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The complete mitochondrial genome of (Linnaeus, 1758) (Diptera: Oestridae).

Mitochondrial DNA B Resour 2021 Jun 3;6(7):1847-1848. Epub 2021 Jun 3.

Department of Experimental Biology, Jaén University, Jaén, Spain.

Larvae of the sheep bot fly, (Linnaeus, 1758), cause cavitary myiasis in domestic and wild hosts, including man. The complete circular mitogenome was assembled, which is 16,584 bp in length and encodes 13 protein-coding genes, 22 tRNA genes, and two rRNA genes. The phylogenetic tree of and 13 related Oestridae species, with as outgroup, was built. Read More

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The complete mitogenome of Matsumura (Diptera: Chloropidae).

Mitochondrial DNA B Resour 2021 Jun 3;6(7):1844-1846. Epub 2021 Jun 3.

College of Plant Protection, Southwest University, Chongqing, China.

Matsumura is an important pest of rice plants throughout Asia, and has even become a major pest in some regions. Here, we present the complete mitogenome of for the first time. The complete mitogenome is 17,313 bp in length and contains 37 genes (13 protein-coding genes, 22 transfer RNAs, and two ribosomal RNAs) and a control region. Read More

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The complete mitochondrial genome of (Linnaeus, 1767) (Neuroptera: Hemerobiidae: Microminae) with phylogenetic analysis.

Mitochondrial DNA B Resour 2021 Jun 3;6(7):1842-1843. Epub 2021 Jun 3.

Department of Entomology, China Agricultural University, Beijing, China.

The complete mitochondrial (mt) genome of (Linnaeus, 1767) (Neuroptera: Hemerobiidae: Microminae) was assembled and the phylogenetic analysis of Chrysopoidea was conducted. The mt genome was 16,607 bp long including 13 protein-coding genes (PCGs), 22 tRNA genes, 2 rRNA genes, and a control region (CR). Twelve PCGs started with typical ATN, but initiated with TCG. Read More

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Complete mitochondrial genome of (: ).

Mitochondrial DNA B Resour 2021 Jun 3;6(7):1840-1841. Epub 2021 Jun 3.

Anhui Provincial Key Laboratory for Microbial Pest Control, Anhui Agricultural University, Hefei, China.

is a pandemic species in the genus . In this article, we report the first complete sequence of mitochondrial genome from a common entomophthoroid fungus under Illumina next-generation sequencing system. The total length of the mitogenome is 34,984 bp with a GC content of 26. Read More

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The mitochondrial genome of (Diptera: Rhagionidae).

Mitochondrial DNA B Resour 2021 Jun 3;6(7):1837-1839. Epub 2021 Jun 3.

Department of Entomology, College of Plant Protection, China Agricultural University, Beijing, China.

The mitochondrial genome of Yang et Yang, 1997 was sequenced, the new representative of the family Rhagionidae. The complete mitochondrial genome is 16,430 bp totally, which consists of 13 protein-coding genes, two ribosomal RNAs, 22 transfer RNAs, and one non-coding control region. The nucleotide composition is biased toward A and T, accounting for 77. Read More

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The complete chloroplast genome sequence of (Benth.) S. Moore. (Asteraceae).

Mitochondrial DNA B Resour 2021 Jun 3;6(7):1834-1836. Epub 2021 Jun 3.

Kunming Medical University Haiyuan College, Kunming, China.

The complete chloroplast (cp) genome of was sequenced and assembled for the first time. In this study, the total genome size is 150,596 bp in length and demonstrates a typical quadripartite structure containing a large single copy (LSC, 82,575 bp) and a small single copy (SSC, 18,293 bp), separated by a pair of inverted repeats (IRa, IRb) of 24,864 bp. The G + C content of this cp genome was 37. Read More

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The complete chloroplast genome sequence of (Verbenaceae).

Mitochondrial DNA B Resour 2021 Jun 3;6(7):1832-1833. Epub 2021 Jun 3.

College of Marine Science and Biological Engineering, Qingdao University of Science and Technology, Qingdao, China.

In this study, the complete chloroplast (cp) genome of was assembled using Illumina sequencing data. The complete cp genome is 149,869 bp in length, including a pair of invert repeats (IRA and IRB) regions of 22,839 bp, large single-copy (LSC) region of 86,201 bp, and small single-copy (SSC) region of 17,990 bp. The G + C content of this cp genome was 38. Read More

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The complete chloroplast genome and phylogenetic analysis of subsp. (Rupr.) P.S.Green & M.C.Chang from Qinghai Province, China.

Mitochondrial DNA B Resour 2021 Jun 3;6(7):1829-1831. Epub 2021 Jun 3.

Key Laboratory of Restoration Ecology in Cold Region of Qinghai Province, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining, China.

subsp. (Rupr.) P. Read More

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Complete chloroplast genome of by sequencing.

Mitochondrial DNA B Resour 2021 Jun 4;6(7):1826-1828. Epub 2021 Jun 4.

College of Biological and Pharmaceutical Engineering, West Anhui University, Lu'an, P. R. China.

(Mart.) () is an important herbage species, which could provide high-quality feed for livestock and poultry breeding. This paper is the first to report the chloroplast genomes, which were detected by sequencing. Read More

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The complete chloroplast genome of .

Mitochondrial DNA B Resour 2021 Jun 3;6(7):1824-1825. Epub 2021 Jun 3.

Chengdu Academy of Agricultural and Forestry Sciences, Chengdu, Sichuan, China.

is of the unique edible bamboo specie of high quality in China. We studied the complete chloroplast(cp) genome of in this study. The cp genome of (GenBank accession: MW186792) was 138,911 bp in length, including a large single-copy (LSC) region of 82,498 bp, a small single-copy (SSC) region of 12,743 bp and a pair of inverted repeated (IR) regions of 21,835 bp. Read More

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The complete chloroplast genome of a purple Ethiopian rape (: Brassicaceae) from Guizhou Province, China and its phylogenetic analysis.

Mitochondrial DNA B Resour 2021 Jun 3;6(7):1821-1823. Epub 2021 Jun 3.

School of Life Sciences, Guizhou Normal University, Guiyang, People's Republic of China.

A. Braun (Ethiopian rape), which was derived from the interspecific hybridization between and , is used as both an oilseed and a leafy vegetable. The complete chloroplast (cp) genome of a purple was obtained. Read More

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Sequencing and analysis of the complete mitochondrial genome of from China and its phylogenetic analysis.

Mitochondrial DNA B Resour 2021 May 31;6(7):1805-1807. Epub 2021 May 31.

College of Life Science and Technology, Mudanjiang Normal University, Mudanjiang, PR China.

The complete mitogenome sequence of was determined using long PCR. The genome was 17,063 bp in length and contained 13 protein-coding genes, two ribosomal RNA genes, 22 transfer RNA genes, one origin of L strand replication, and one control region. The overall base composition of the heavy strand is A (31. Read More

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The complete chloroplast genome of 'Yulinglong' ( var. ) with double-petaled in southeast of China.

Mitochondrial DNA B Resour 2021 Jun 2;6(6):1765-1767. Epub 2021 Jun 2.

College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou, Fujian, China.

In this study, the complete chloroplast (cp) genome of var. cv 'Yulinglong' was sequenced and assembled by next-generation sequencing. The complete cp genome is 159,376 in length and contained 137 genes, consisting of 91 protein-coding genes, eight ribosomal RNA genes, and 38 transfer RNA genes. Read More

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The complete chloroplast genome sequence of Sieb. & Zucc. (Lythraceae).

Mitochondrial DNA B Resour 2021 Jun 2;6(6):1732-1733. Epub 2021 Jun 2.

Hubei Key Laboratory of Wetland Evolution & Ecological Restoration, Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, P. R. China.

L., an annual floating-leaved herb, is widely distributed in the old world and has important edible and medicinal values. However, the taxonomy and phylogeny of are unclear. Read More

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Characterization of the complete mitochondrial genome of (Decapoda: Hippolytidae).

Mitochondrial DNA B Resour 2021 Jun 2;6(6):1718-1720. Epub 2021 Jun 2.

Food and Drug College, Qingyuan Polytechnic, Qingyuan, China.

is widely distributed in the Indian and Pacific oceans. In this study, we sequenced the mitochondrial genome of using Illumina HiSeq. The complete mitochondrial genome of was 20,837 bp in length, including 13 protein-coding genes, 22 transfer RNA genes, and two ribosomal RNA genes. Read More

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An Immune-Related Long Non-Coding RNA Signature to Predict the Prognosis of Ewing's Sarcoma Based on a Machine Learning Iterative Lasso Regression.

Front Cell Dev Biol 2021 26;9:651593. Epub 2021 May 26.

Breast Disease Diagnosis and Treatment Center, Affiliated Hospital of Qinghai University, Affiliated Cancer Hospital of Qinghai University, Xining, China.

The aim of this study was to construct a new immune-associated long non-coding RNA (lncRNA) signature to predict the prognosis of Ewing sarcoma (ES) and explore its molecular mechanisms. We downloaded transcriptome and clinical prognosis data from the Gene Expression Omnibus (GSE17679, which included 88 ES samples and 18 matched normal skeletal muscle samples), and used it as a training set to identify immune-related lncRNAs with different expression levels in ES. Univariable Cox regression was used to screen immune-related lncRNAs related to ES prognosis, and an immune-related lncRNA signature was constructed based on machine learning iterative lasso regression. Read More

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Gene Instability-Related lncRNA Prognostic Model of Melanoma Patients via Machine Learning Strategy.

J Oncol 2021 25;2021:5582920. Epub 2021 May 25.

Department of Dermatology, The First Hospital of China Medical University, National Health Commission Key Laboratory of Immunodermatology, Key Laboratory of Immunodermatology of Ministry of Education, Shenyang, Liaoning, China.

Background: Melanoma is a common tumor characterized by a high mortality rate in its late stage. After metastasis, current treatment methods are relatively ineffective. Many studies have shown that long noncoding RNA (lncRNA) may participate in gene mutation and genomic instability in cancer. Read More

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Characterization of the Complete Mitochondrial Genome of Basidiomycete Yeast : Intron Evolution, Gene Rearrangement, and Its Phylogeny.

Front Microbiol 2021 28;12:646567. Epub 2021 May 28.

Biotechnology and Nuclear Technology Research Institute, Sichuan Academy of Agricultural Sciences, Chengdu, China.

In this study, the mitogenome of was sequenced by next-generation sequencing (NGS) and successfully assembled. The mitogenome comprised circular DNA molecules with a total size of 26,444 bp. We found that the mitogenome of partially deleted the tRNA gene transferring cysteine. Read More

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Positive natural selection of N6-methyladenosine on the RNAs of processed pseudogenes.

Genome Biol 2021 Jun 13;22(1):180. Epub 2021 Jun 13.

Department of Medical Informatics, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.

Background: Canonical nonsense-mediated decay (NMD) is an important splicing-dependent process for mRNA surveillance in mammals. However, processed pseudogenes are not able to trigger NMD due to their lack of introns. It is largely unknown whether they have evolved other surveillance mechanisms. Read More

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Functional examination of lncRNAs in allotetraploid Gossypium hirsutum.

BMC Genomics 2021 Jun 13;22(1):443. Epub 2021 Jun 13.

College of Agriculture and Biotechnology, Zhejiang University, 210058, Hangzhou, Zhejiang, China.

Background: An evolutionary model using diploid and allotetraploid cotton species identified 80 % of non-coding transcripts in allotetraploid cotton as being uniquely activated in comparison with its diploid ancestors. The function of the lncRNAs activated in allotetraploid cotton remain largely unknown.

Results: We employed transcriptome analysis to examine the relationship between the lncRNAs and mRNAs of protein coding genes (PCGs) in cotton leaf tissue under abiotic stresses. Read More

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Positive Selection as a Key Player for SARS-CoV-2 Pathogenicity: Insights into ORF1ab, S and E genes.

Virus Res 2021 Jun 9:198472. Epub 2021 Jun 9.

Center for Informatics Sciences (CIS), Nile University, Giza, Egypt.

The human β-coronavirus SARS-CoV-2 epidemic started in late December 2019 in Wuhan, China. It causes Covid-19 disease which has become pandemic. Each of the five-known human β-coronaviruses has four major structural proteins (E, M, N and S) and 16 non-structural proteins encoded by ORF1a and ORF1b together (ORF1ab) that are involved in virus pathogenicity and infectivity. Read More

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Assessment of a complete and classified platelet proteome from genome-wide transcripts of human platelets and megakaryocytes covering platelet functions.

Sci Rep 2021 Jun 11;11(1):12358. Epub 2021 Jun 11.

Department of Biochemistry, CARIM, Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.

Novel platelet and megakaryocyte transcriptome analysis allows prediction of the full or theoretical proteome of a representative human platelet. Here, we integrated the established platelet proteomes from six cohorts of healthy subjects, encompassing 5.2 k proteins, with two novel genome-wide transcriptomes (57. Read More

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Pan-ancestry exome-wide association analyses of COVID-19 outcomes in 586,157 individuals.

Am J Hum Genet 2021 Jun 3. Epub 2021 Jun 3.

Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge CB2 0AA, UK.

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), a respiratory illness that can result in hospitalization or death. We used exome sequence data to investigate associations between rare genetic variants and seven COVID-19 outcomes in 586,157 individuals, including 20,952 with COVID-19. After accounting for multiple testing, we did not identify any clear associations with rare variants either exome wide or when specifically focusing on (1) 13 interferon pathway genes in which rare deleterious variants have been reported in individuals with severe COVID-19, (2) 281 genes located in susceptibility loci identified by the COVID-19 Host Genetics Initiative, or (3) 32 additional genes of immunologic relevance and/or therapeutic potential. Read More

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Genomic insights into molecular adaptation to intertidal environments in the mangrove Aegiceras corniculatum.

New Phytol 2021 Jun 11. Epub 2021 Jun 11.

State Key Laboratory of Biocontrol, Guangdong Key Lab of Plant Resources, School of Life Sciences, Sun Yat-sen University, Guangzhou, 510275, China.

Mangroves have colonized extreme intertidal environments characterized by high salinity, hypoxia, and other abiotic stresses. Aegiceras corniculatum, a pioneer mangrove species that evolved two specialized adaptive traits (salt secretion and crypto-vivipary), is an attractive ecological model to investigate molecular mechanisms underlying adaptation to intertidal environments. We de novo assembled a high-quality reference genome of A. Read More

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Complete genome sequence of a novel fish papillomavirus detected in farmed wels catfish (Silurus glanis).

Arch Virol 2021 Jun 11. Epub 2021 Jun 11.

Institute for Veterinary Medical Research, Centre for Agricultural Research, ELKH, 1143 Budapest, Hungária krt. 21., P.O. Box 18, 1581, Budapest, Hungary.

A novel papillomavirus (PV) was detected in farmed wels catfish (Silurus glanis) in Hungary showing clinical signs resembling those of wels catfish herpesvirus disease. The whole genome of Silurus glanis papillomavirus 1 (SgPV1) was identified using next-generation sequencing. The 5,612-bp complete genome contains four predicted protein coding regions (E1, E2, L1, and L2), which seem to have homologues in every PV genome sequenced to date. Read More

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The Complete Mitochondrial Genome of Lepidotrigona flavibasis (Hymenoptera: Meliponini) and High Gene Rearrangement in Lepidotrigona Mitogenomes.

J Insect Sci 2021 May;21(3)

Research Institute of Resource Insects, Chinese Academy of Forestry, Kunming, China.

We reported the sequence and characteristics of the complete mitochondrial genome of an ecologically important stingless bee, Lepidotrigona flavibasis (Hymenoptera: Meliponini), that has suffered serious population declines in recent years. A phylogenetic analysis based on complete mitogenomes indicated that L. flavibasis was first clustered with another Lepidotrigona species (L. Read More

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