Plant Physiol 2015 Nov 15;169(3):2230-43. Epub 2015 Sep 15.
Departments of Plant Pathology (G.-F.W., Y.H., B.A.O., P.J.B.-K.),Plant and Microbial Biology (R.S., X.L.), andBiological Sciences (D.N.), North Carolina State University, Raleigh, North Carolina 27695;Plants for Human Health Institute, North Carolina State University, Kannapolis, North Carolina 28081 (R.S., X.L.); andPlant Science Research Unit, United States Department of Agriculture-Agricultural Research Service, Raleigh, North Carolina 27695 (P.J.B.-K.)
In plants, most disease resistance genes encode nucleotide binding Leu-rich repeat (NLR) proteins that trigger a rapid localized cell death called a hypersensitive response (HR) upon pathogen recognition. The maize (Zea mays) NLR protein Rp1-D21 derives from an intragenic recombination between two NLRs, Rp1-D and Rp1-dp2, and confers an autoactive HR in the absence of pathogen infection. From a previous quantitative trait loci and genome-wide association study, we identified a single-nucleotide polymorphism locus highly associated with variation in the severity of Rp1-D21-induced HR. Read More