Toxins (Basel) 2021 04 29;13(5). Epub 2021 Apr 29.
USDA, Agricultural Research Service, Mycotoxin Prevention and Applied Microbiology Research Unit, National Center for Agricultural Utilization Research, 1815 N. University street, Peoria, IL 61604, USA.
, the causal agent of Fusarium head blight (FHB), produces trichothecenes including deoxynivalenol (DON), nivalenol (NIV), and 3,7,15-trihydroxy-12,13-epoxytrichothec-9-ene (NX-3). These toxins contaminate grains and cause profound health problems in humans and animals. To explore exploiting a fungal self-protection mechanism in plants, we examined the ability of trichothecene 3--acetyltransferase () to detoxify several key trichothecenes produced by : DON, 15-ADON, NX-3, and NIV. Read More