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Traumatic experiences and resilience: Associations with mental health, death attitudes, and religion in university students.

Death Stud 2021 Apr 13:1-11. Epub 2021 Apr 13.

Psychology Department, University of Girona, Girona, Spain.

Resilience may be related to mental health and profound beliefs and attitudes. Utilizing a survey design, we examined relationships among resilience, clinical syndromes, death attitudes, and religion. Mexican university students ( = 161) answered a sociodemographic questionnaire, the Global Post-Traumatic Stress Scale, the Millon Multiaxial Inventory, the Connor-Davidson Resilience Scale, and the Death Attitudes Profile. Read More

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TREM2 Dictates Antibacterial Defense and Viability of Bone Marrow-derived Macrophages During Bacterial Infection.

Am J Respir Cell Mol Biol 2021 Apr 13. Epub 2021 Apr 13.

Zhejiang University School of Medicine First Affiliated Hospital, 71069, Anesthesiology and Intensive Care, Hangzhou, China;

Macrophages undergo profound metabolic reprogramming to join key immunoregulatory functions, which can be initiated by pattern recognition receptors. TREM2, a macrophage phagocytic receptor, plays pivotal roles in sepsis by enhancing bacterial clearance, which is associated with regulation of reactive oxygen species (ROS) production. However, how intracellular ROS participate in TREM2-mediated bactericidal activity remains unclear. Read More

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Splenic Artery Embolization for Treatment of Iatrogenic Kasabach-Merritt Phenomenon Following Failed Endovascular Splenic Artery Aneurysm Repair.

Vasc Endovascular Surg 2021 Apr 13:15385744211003470. Epub 2021 Apr 13.

Division of Vascular and Interventional Radiology, Department of Radiology, University of Minnesota, MN, USA.

Stent grafts are utilized to treat and exclude visceral arterial aneurysms while preserving flow through the vessel. Stent-associated thrombocytopenia is a rare complication not typically seen with modern stents. The following case describes the clinical presentation of stent kinking and consumptive coagulopathy. Read More

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Protective effects of farnesyltransferase inhibitor on sepsis-induced morphological aberrations of mitochondria in muscle and increased circulating mitochondrial DNA levels in mice.

Biochem Biophys Res Commun 2021 Apr 9;556:93-98. Epub 2021 Apr 9.

Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129, USA; Shriners Hospitals for Children, Boston, MA, 02114, USA.

Sepsis remains a leading cause of mortality in critically ill patients and is characterized by multi-organ dysfunction. Mitochondrial damage has been proposed to be involved in the pathophysiology of sepsis. In addition to metabolic impairments resulting from mitochondrial dysfunction, mitochondrial DNA (mtDNA) causes systemic inflammation as a damage-associated molecular pattern when it is released to the circulation. Read More

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