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Occupational Contact Dermatitis: Return to Work Using a Multidisciplinary Clinic Model.

Contact Dermatitis 2021 Jul 22. Epub 2021 Jul 22.

Department of Medicine, University of Toronto, Toronto, CANADA.

Background: Occupational contact dermatitis often results in work disruption. Return-to-work (RTW) is an important outcome.

Objective: The objective of this study was to determine RTW outcomes and factors associated with such outcomes using a multidisciplinary clinic model. Read More

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Effects of riverbank erosion on mental health of the affected people in Bangladesh.

PLoS One 2021 22;16(7):e0254782. Epub 2021 Jul 22.

Department of Statistics, Islamic University, Kushtia, Bangladesh.

Background: In Bangladesh, riverbank erosion is a major problem that regularly displaces millions of people and affects their mental health every year.

Objectives: The primary objective is to explore the effects of riverbank erosion on mental health problems such as depression, anxiety, and stress in Bangladesh.

Methods: We conducted a household survey from August 2019 to November 2019 on randomly selected adult respondents from Rajbari District located along the Ganges River and Tangail District located along the Brahmaputra River. Read More

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Telestroke for acute ischaemic stroke: A systematic review of economic evaluations and a de novo cost-utility analysis for a middle income country.

J Telemed Telecare 2021 Jul 22:1357633X211032407. Epub 2021 Jul 22.

Deakin Health Economics, Institute for Health Transformation, 2104Deakin University, Australia.

Introduction: Telemedicine can alleviate the problems faced in rural settings in providing access to specialist stroke care. The evidence of the cost-effectiveness of this model of care outside high-income countries is limited. This study aimed to conduct: (a) a systematic review of economic evaluations of telestroke and (b) a cost-utility analysis of telestroke, using China as a case study. Read More

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Identifying Risk Factors for Self-reported Mental Health Problems in Psychiatry Trainees and Psychiatrists in Mexico.

Acad Psychiatry 2021 Jul 21. Epub 2021 Jul 21.

Universidad Nacional Autónoma de México, Mexico City, Mexico.

Objective: The objective was to determine and compare demographic features, professional activities and adversities, physical health conditions, and self-care behaviors related to the most frequently self-reported mental health problems among psychiatrists and psychiatry trainees.

Methods: A cross-sectional, retrospective, comparative study was conducted on a total of 330 (48.2%) psychiatry trainees and 355 (51. Read More

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Insights into the management of anorectal disease in the coronavirus 2019 disease era.

Therap Adv Gastroenterol 2021 9;14:17562848211028117. Epub 2021 Jul 9.

Section of Cardiology in Division of Internal Medicine, University of Massachusetts School of Medicine, Worcester, MA 01655, USA.

Coronavirus 2019 disease (COVID-19) has created major impacts on public health. The virus has plagued a large population requiring hospitalization and resource utilization. Knowledge about the COVID-19 virus continues to grow. Read More

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Health-related quality of life in different trimesters during pregnancy.

Health Qual Life Outcomes 2021 Jul 21;19(1):182. Epub 2021 Jul 21.

Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, China.

Background: Pregnant women experience physical, physiological, and mental changes. Health-related quality of life (HRQoL) is a relevant indicator of psychological and physical behaviours, changing over the course of pregnancy. This study aims to assess HRQoL of pregnant women during different stages of pregnancy. Read More

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Otago exercise programme for physical function and mental health among older adults with cognitive frailty during COVID-19: A randomised controlled trial.

J Clin Nurs 2021 Jul 21. Epub 2021 Jul 21.

The Second Xiangya Hospital, Central South University, Changsha, China.

Aims And Objectives: Quarantine during the COVID-19 pandemic resulted in longer-term sedentary behaviours and mental health problems. Our study aimed to evaluate the impact of the Otago exercise programme (OEP) on physical function and mental health among elderly with cognitive frailty during COVID-19.

Background: Lockdowns and restrictions during the COVID-19 pandemic result in longer-term sedentary behaviours related disease and mental problem. Read More

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Food insecurity during COVID-19 pandemic: A genuine concern for people from disadvantaged community and low-income families in Province 2 of Nepal.

PLoS One 2021 21;16(7):e0254954. Epub 2021 Jul 21.

Department of Allied Health Professions, Sports and Exercise, School of Human and Health Sciences, University of Huddersfield, Huddersfield, United Kingdom.

Background: Food insecurity is a serious social and public health problem which is exacerbated by the COVID-19 pandemic especially in resource-poor countries such as Nepal. However, there is a paucity of evidence at local levels. This study aims to explore food insecurity among people from the disadvantaged community and low-income families during the COVID-19 pandemic in Province-2 of Nepal. Read More

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Technical Note: Comparison of Convolutional Neural Networks for Detecting Large Vessel Occlusion on Computed Tomography Angiography.

Med Phys 2021 Jul 21. Epub 2021 Jul 21.

Department of Computer Science, Vanderbilt University, Nashville, TN, 37235, USA.

Purpose: Artificial intelligence diagnosis and triage of large vessel occlusion may quicken clinical response for a subset of time-sensitive acute ischemic stroke patients, improving outcomes. Differences in architectural elements within data-driven convolutional neural network (CNN) models impact performance. Foreknowledge of effective model architectural elements for domain-specific problems can narrow the search for candidate models and inform strategic model design and adaptation to optimize performance on available data. Read More

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Evaluation of Three Feasibility Tools for Identifying Patient Data and Biospecimen Availability: Comparative Usability Study.

JMIR Med Inform 2021 Jul 21;9(7):e25531. Epub 2021 Jul 21.

Institute for Medical Informatics and Biometry, Carl Gustav Carus Faculty of Medicine, Technische Universität Dresden, Dresden, Germany.

Background: To meet the growing importance of real-word data analysis, clinical data and biosamples must be timely made available. Feasibility platforms are often the first contact point for determining the availability of such data for specific research questions. Therefore, a user-friendly interface should be provided to enable access to this information easily. Read More

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Biomimetic-Coated Nanoplatform with Lipid-Specific Imaging and ROS Responsiveness for Atherosclerosis-Targeted Theranostics.

ACS Appl Mater Interfaces 2021 Jul 21. Epub 2021 Jul 21.

National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, China.

Atherosclerosis is one of the leading causes of cardiovascular diseases and is triggered by endothelial damage, local lipid cumulation, and inflammation. Despite the conventional medication treatment, nanosized drug carriers have become promising candidates for efficient drug delivery with lower side effects. However, the development of problems in nanocarriers such as drug leakage, accumulating efficiency, and accurate drug release, as well as the specific recognition of atherosclerotic plaques, still needs to be checked. Read More

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Exchange transfusion for neonatal hyperbilirubinemia: A multicenter, prospective study of Turkish Neonatal Society.

Turk Arch Pediatr 2021 Mar 6;56(2):121-126. Epub 2021 Jan 6.

Department of Pediatrics, Division of Neonatology, Ankara University Faculty of Medicine, Ankara, Turkey.

Objective: The frequency of neonatal exchange transfusion has declined in recent years, but is still performed in many countries. The procedure is associated with complications. The aim of the study was to determine the clinical features and etiologies of infants with hyperbilirubinemia who underwent exchange transfusion and evaluate the adverse events and clinical outcomes. Read More

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Bayesian optimization for goal-oriented multi-objective inverse material design.

Kyohei Hanaoka

iScience 2021 Jul 24;24(7):102781. Epub 2021 Jun 24.

Advanced Technology Research & Development Center, Showa Denko Materials Co., Ltd., 48 Wadai, Tsukuba City, Ibaraki Prefecture 300-4247, Japan.

Bayesian optimization (BO) can accelerate material design requiring time-consuming experiments. However, although most material designs require tuning of multiple properties, the efficiency of multi-objective (MO) BO in time-consuming experimental material design remains unclear, due to the complexity of handling multiple objectives. This study introduces MO BO method that efficiently achieves predefined goals and shows that by focusing on achieving the goals, BO can efficiently accelerate realistic MO design problems with small efforts. Read More

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Voice-Related Problems, Vocal and Non-Vocal Habits in Naradiya Kirtankars: A Preliminary Study.

J Voice 2021 Jul 17. Epub 2021 Jul 17.

Department of Audiology and Speech Language Pathology, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India-576104. Electronic address:

Objective: Naradiya kirtan is a part of India's rich folk heritage. Voice demands of the kirtankar (kirtan performer) include a combination of recitation, narration, and singing. Slight to moderate deviations in their voice could hamper their public image as well as endanger their career. Read More

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General Purpose Low-Level Reinforcement Learning Control for Multi-Axis Rotor Aerial Vehicles.

Sensors (Basel) 2021 Jul 2;21(13). Epub 2021 Jul 2.

Department of Mechanical Engineering, National Yang Ming Chiao Tung University, Hsinchu City 30010, Taiwan.

This paper proposes a multipurpose reinforcement learning based low-level multirotor unmanned aerial vehicles control structure constructed using neural networks with model-free training. Other low-level reinforcement learning controllers developed in studies have only been applicable to a model-specific and physical-parameter-specific multirotor, and time-consuming training is required when switching to a different vehicle. We use a 6-degree-of-freedom dynamic model combining acceleration-based control from the policy neural network to overcome these problems. Read More

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A Collaborative Application for Assisting the Management of Household Plastic Waste through Smart Bins: A Case of Study in the Philippines.

Sensors (Basel) 2021 Jul 1;21(13). Epub 2021 Jul 1.

Polytechnic School, Catholic University of Murcia (UCAM), 30107 Murcia, Spain.

The management and collection of household waste often represents a demanding task for elderly or impaired people. In particular, the increasing generation of plastic waste at home may pose a problem for these groups, as this type of waste accumulates very rapidly and occupies a considerable amount of space. This paper proposes a collaborative infrastructure to monitor household plastic waste. Read More

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Analysis of Periodontal Conditions in the Provinces of Vietnam: Results From the National Dental Survey.

Asia Pac J Public Health 2021 Jul 20:10105395211029803. Epub 2021 Jul 20.

VNU University of Science, Vietnam National University, Ha Noi, Vietnam.

Nationwide dental health surveys are crucial for providing essential information on dental health and dental condition-related problems in the community. However, the relationship between periodontal conditions and sociodemographic data has not been well investigated in Vietnam. With data from the National Oral Health Survey in 2019, we performed several machine learning methods on this dataset to investigate the impacts of sociodemographic features on gingival bleeding, periodontal pockets, and Community Periodontal Index. Read More

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The Relationship Between Functional Motor Status and Self-evaluation in Individuals With Cerebral Palsy: A Systematic Review.

Iran J Child Neurol 2021 ;15(3):9-27

Department of Occupational Therapy, School of Rehabilitation Sciences, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.

Cerebral palsy (CP) is a common pediatric disorder that results in a wide range of motor and functional problems that impose mobility limitations, decrease the quality of movement, negatively affect physical activity participation, self-care, and academic performance, and ultimately result in social isolation and negative self-evaluation. Despite abundant evidence of motor function, very few studies investigated all aspects of self-evaluation or described the relationship between motor function and self in individuals with CP. The present study aimed at investigating the relationship between functional motor status and self-evaluation in individuals with CP. Read More

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January 2021

Evaluation of Arthrocentesis with hyaluronic acid injections for management of temporomandibular disorders: a systematic review and case series.

J Biol Regul Homeost Agents 2021 Mar-Apr;35(2 Suppl. 1):21-35

Department of Biomedical, Surgical and Dental Sciences, Università degli studi di Milano, Milan, Italy.

Although arthrocentesis is an accepted safe treatment modality for the management of temporomandibular disorders (TMD) in symptomatic patients, the benefit of hyaluronic acid (HA) injections remains uncertain. The aim of this study was to evaluate whether intra-articular HA injections adjunctive to arthrocentesis can be more effective than other medications for the improvement of TMD associated symptoms. Additionally, the impact of HA injections on quality of life of TMD patients was assessed with SF-36® questionnaire in a cohort of patients. Read More

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Associations between prospective and retrospective measures of child abuse and self-reported adult health at midlife.

Child Abuse Negl 2021 Jul 16;120:105203. Epub 2021 Jul 16.

University of Southern California Suzanne Dworak-Peck School of Social Work, United States of America.

Background: The long-term health effects of physical child abuse are well documented in self-report, retrospective studies. However, there have been few longitudinal, multimethod studies on physiological responses to stress and the onset of chronic disease, thereby slowing the advancement of prevention and intervention programs.

Objectives: This study used survey data from an extended longitudinal study to examine prospective and retrospective associations between measures of physical child abuse and adult health in the 40s. Read More

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Study on anti-scaling of landfill leachate treated by evaporation method.

Water Sci Technol 2021 Jul;84(1):122-134

School of Chemical Engineering, University of Science and Technology Liaoning, Anshan 114051, China.

In the mechanical vapor recompression (MVR) treatment of landfill leachate, scaling in the evaporator and heat exchanger poses a serious problem. This study explored the reasons for such scaling and proposed acid or ion-exchange pre-treatments to reduce the alkalinity of the landfill leachate nanofiltration concentrate (LLNC) to prevent scaling. The feasibility of these two methods was evaluated and the technical and economic parameters for application were obtained via experiments. Read More

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Task-induced Pyramid and Attention GAN for Multimodal Brain Image Imputation and Classification in Alzheimers disease.

IEEE J Biomed Health Inform 2021 Jul 19;PP. Epub 2021 Jul 19.

With the advance of medical imaging technologies, multimodal images such as magnetic resonance images (MRI) and positron emission tomography (PET) can capture subtle structural and functional changes of brain, facilating the diagnosis of brain diseases such as Alzheimers disease (AD). In practice, multimodal images may be incomplete since PET is often missing due to high financial cost or availability. Most of existing methods simply excluded subjects with missing data, which unfortunately reduced sample size. Read More

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Systematic Literature Review and Quantitative Analysis of Health Problems Associated with Sexually Transmitted Neisseria gonorrhoeae Infection.

Infect Dis Ther 2021 Jul 17. Epub 2021 Jul 17.

GSK, Wavre, Belgium.

Objective: Neisseria gonorrhoeae (Ng) is the second most common sexually transmitted bacterial infection (STI), leading to serious health problems in men, women and newborns. While early antibiotic treatment is effective, infections are increasingly antibiotic-resistant. No systematic reviews present health problems associated with Ng infections or their likelihood of occurrence. Read More

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Patients' preferences for treatment with the new direct acting antiviral therapies for chronic hepatitis C virus infection.

Rev Esp Sanid Penit 2021 May-Aug;23(2):67-75

Department of Internal Medicine. Hospital Universitario Infanta Leonor. Madrid.

Objectives: The efficacy of new direct-acting antivirals (DAAs) in treating hepatitis C infection can depend on treatment adherence, which may be influenced by the patient's current lack of awareness of the disease. This study set out to understand the treatment naïve chronic hepatitis C patients' preferences for new DAAs (attributes) and to compile information about the diagnosis process.

Material And Method: Spanish quantitative market research study conducted between November 2018 and January 2019 to assess the posology preferences of treatment-naïve patients with chronic hepatitis C before starting treatment (seen by hepatologists and infectious diseases specialists). Read More

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February 2021

Biocompatibility Parameters with Standard and Increased Dose of Citrate in Hemodialysis-A Randomized Trial.

J Clin Med 2021 Jul 4;10(13). Epub 2021 Jul 4.

Department of Nephrology, University Medical Center Ljubljana, 1000 Ljubljana, Slovenia.

Background: The dose of citrate needed in regional citrate anticoagulation (RCA) to achieve optimal biocompatibility is unknown. We performed a randomized trial comparing two doses (ACTRN12613001340729).

Methods: In 30 patients a single hemodialysis with either standard (2. Read More

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Temporal Imaging of Live Cells by High-Speed Confocal Raman Microscopy.

Materials (Basel) 2021 Jul 3;14(13). Epub 2021 Jul 3.

Laser Biomedical Research Center, G. R. Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Label-free live cell imaging was performed using a custom-built high-speed confocal Raman microscopy system. For various cell types, cell-intrinsic Raman bands were monitored. The high-resolution temporal Raman images clearly delineated the intracellular distribution of biologically important molecules such as protein, lipid, and DNA. Read More

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Network pharmacological evaluation of bioactive phytochemicals for identifying novel potential inhibitors against neurodegenerative disorder.

J Biomol Struct Dyn 2021 Jul 19:1-12. Epub 2021 Jul 19.

Amity Institute of Biotechnology, Amity University, Noida, India.

Neurodegenerative disorders are illnesses that are responsible for neuronal cell death and resulting in lifelong cognitive problems. Due to their unclear mechanism, there are no effective drugs available for the treatment. For a long time, herbal drugs have been used as a role model in the field of the drug discovery process. Read More

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Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the detection of dementia within a secondary care setting.

Cochrane Database Syst Rev 2021 Jul 19;7:CD010772. Epub 2021 Jul 19.

Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.

Background: The diagnosis of dementia relies on the presence of new-onset cognitive impairment affecting an individual's functioning and activities of daily living. The Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) is a questionnaire instrument, completed by a suitable 'informant' who knows the patient well, designed to assess change in functional performance secondary to cognitive change; it is used as a tool for identifying those who may have dementia. In secondary care there are two specific instances where patients may be assessed for the presence of dementia. Read More

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Changes in Lumbosacral Anatomy and Vertebral Numbering in Patients with Thoracolumbar and/or Lumbosacral Transitional Vertebrae.

JB JS Open Access 2021 Jul-Sep;6(3). Epub 2021 Jul 14.

Spine Center, Yokohama Minami Kyosai Hospital, Kanagawa, Japan.

The presence of a thoracolumbar transitional vertebra (TLTV) and/or lumbosacral transitional vertebra (LSTV) may cause wrong-site surgery and problems while measuring spinopelvic parameters, including pelvic incidence and lumbar lordosis. The Castellvi classification of LSTV addresses coronal images but not sagittal or axial images. Therefore, it is unclear how LSTV differs from the normal lumbosacral anatomy. Read More

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The global prevalence of depression, anxiety, stress, and, insomnia and its changes among health professionals during COVID-19 pandemic: A rapid systematic review and meta-analysis.

Heliyon 2021 Jul 26;7(7):e07393. Epub 2021 Jun 26.

Institute of Statistical Research and Training, University of Dhaka, Bangladesh.

Background: During the COVID-19 pandemic, the health professionals who are at the frontline of this crisis have been facing extreme psychological disorders. This research aims to provide an overall scenario of the prevalence of depression, anxiety, stress, as well as insomnia and to inspect the changes in these prevalence over time by analyzing the existing evidence during this COVID-19 pandemic.

Methods: A systematic search was performed on March 30, 2021, in PubMed, MEDLINE, Google Scholar databases, and Web of Science. Read More

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