Shock 2021 May 18. Epub 2021 May 18.
Walter Reed National Military Medical Center, The Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA R Adams Cowley Shock Trauma Center, University of Maryland Medical System, Maryland, USA Prytime Medical, Boerne, Texas, USA.
Abstract: Resuscitative endovascular balloon occlusion of the aorta (REBOA) allows for effective temporization of exsanguination from non-compressible hemorrhage (NCTH) below the diaphragm. However, the therapeutic window for aortic occlusion is time-limited given the ischemia-reperfusion injury generated. Significant effort has been put into translational research to develop new strategies to alleviate the ischemia-reperfusion injury and extend the application of endoaortic occlusion. Read More