1,881,071 results match your criteria prevention preterm

The Gender-Sensitive Social Risk Factors for Internet Addiction in College Undergraduate Students.

Psychiatry Investig 2021 Jul 22;18(7):636-644. Epub 2021 Jul 22.

Mental Health Center and Psychiatric Laboratory, Huaxi Brain Research Center, West China Hospital of Sichuan University, Chengdu, China.

Objective: The current study aims to explore precipitating and social risk factors for internet addiction (IA) in university undergraduate students, and to provide evidence for interventions and the early prevention of IA in different genders.

Methods: Four thousand eight hundred and fifty-eight college sophomores completed an online survey on their internet use-related behaviours and social risk factors.

Results: We found that more male (8. Read More

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Prediction of diabetic protein markers based on an ensemble method.

Front Biosci (Landmark Ed) 2021 Jul;26(7):207-221

School of Opto-electronic and Communication Engineering, Xiamen University of Technology, 361024 Xiamen, Fujian, China.

: A diabetic protein marker is a type of protein that is closely related to diabetes. This kind of protein plays an important role in the prevention and diagnosis of diabetes. Therefore, it is necessary to identify an effective method for predicting diabetic protein markers. Read More

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Antiseizure medication nonadherence and its associated factors among Epileptic patients in Ethiopia, a systematic review and meta-analysis.

Seizure 2021 Jul 26;91:462-475. Epub 2021 Jul 26.

College of Nursing, University of Saskatchewan, Saskatoon, Canada; School of Life Sciences and Bioengineering, Nelson Mandela African Institute of Science and Technology, Arusha, Tanzania. Electronic address:

Background: The majority of patients with epilepsy in resource-poor countries never receive proper treatment, and those who are started on anti-seizure medications quickly discontinue them. Medication noncompliance is extremely common, with estimates ranging from 26 to 79 percent. Non-adherence to antiseizure medications is associated with poor seizure control, increased morbidity, increased hospitalization time, poor quality of life, increased health care costs, and increased mortality in adults. Read More

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Improved soil-crop system management aids in NH emission mitigation in China.

Environ Pollut 2021 Jul 26;289:117844. Epub 2021 Jul 26.

Rothamsted Research, North Wyke, Devon, EX20 2SB, UK.

High ammonia (NH) emissions from fertilized soil in China have led to various concerns regarding environmental safety and public health. In response to China's blue skies protection campaign, effective NH reduction measures need to consider both mitigation efficiency and food security. In this context, we conducted a meta-analysis (including 2980 observations from 447 studies) to select effective measures based on absolute (AV) and yield-scaled (YSAV) NH volatilization reduction potential, with the aim of establishing a comprehensive NH mitigation framework covering various crop production sectors, and offering a range of potential solutions. Read More

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The effect of next day responsibilities and an adaptive purchase task on cannabis demand.

Drug Alcohol Depend 2021 Jul 28;227:108919. Epub 2021 Jul 28.

Department of Clinical and Health Psychology, University of Florida, Gainesville, FL, USA; Center for Pain Research and Behavioral Health, University of Florida, Gainesville, FL, USA. Electronic address:

Background: The marijuana purchase task (MPT) is a commonly used behavioral economic measure of relative cannabis value (i.e. demand) that presents specific methodological concerns due to non-standardized measurement, variability in modality of use, and evolving legalization policies. Read More

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Attitude towards female circumcision among women in Ethiopia.

Sex Reprod Healthc 2021 Jul 27;29:100647. Epub 2021 Jul 27.

Department of Prevention and Community Health, Milken Institute School of Public Health, The George Washington University, Washington, DC, United States.

Female genital mutilation or cutting (FGM/C) is a global phenomenon mostly practiced in Africa, Asia, and the middle east. It involves the removal of the external female genitalia for non-medical reasons. The practice cuts across different ethnic and religious groups in Africa and is associated with several health complications. Read More

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Socioeconomic patterns and COVID-19 outcomes before, during and after the lockdown in Italy (2020).

Health Place 2021 Jul 29;71:102642. Epub 2021 Jul 29.

Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy; Cyprus International Institute for Environmental and Public Health, Cyprus University of Technology, Limassol, Cyprus.

The objective was to investigate the association between deprivation and COVID-19 outcomes in Italy during pre-lockdown, lockdown and post-lockdown periods using a retrospective cohort study with 38,534,169 citizens and 222,875 COVID-19 cases. Multilevel negative binomial regression models, adjusting for age, sex, population-density and region of residence were conducted to evaluate the association between area-level deprivation and COVID-19 incidence, case-hospitalisation rate and case-fatality. During lockdown and post-lockdown, but not during pre-lockdown, higher incidence of cases was observed in the most deprived municipalities compared with the least deprived ones. Read More

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Identification of Streptococcus pseudopneumoniae and other mitis group streptococci using matrix assisted laser desorption/ionization - time of flight mass spectrometry.

Diagn Microbiol Infect Dis 2021 Jul 10;101(3):115487. Epub 2021 Jul 10.

The Regional Department of Clinical Microbiology, Region Zealand, Denmark; Institute of Clinical Medicine, University of Copenhagen, Copenhagen N, Denmark.

This study evaluated the ability of the MALDI-ToF MS from Bruker Daltonics to identify clinical Mitis-Group-Streptococcus isolates with a focus on Streptococcus pseudopneumoniae. The results were analyzed using the standard log(score) and the previously published list(score). Importantly, using the log(score) no misidentifications occurred and 27 of 29 (93%) S. Read More

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Potential protective role of the anti-PD-1 blockade against SARS-CoV-2 infection.

Biomed Pharmacother 2021 Jul 28;142:111957. Epub 2021 Jul 28.

Lab of Chemical Biology and Molecular Drug Design, College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China; Institute of Drug Development & Chemical Biology, Zhejiang University of Technology, Hangzhou 310014, China. Electronic address:

The outbreak of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan, China, in December 2019, and its global dissemination became the coronavirus disease 2019 (COVID-19) pandemic declared by the World Health Organization (WHO) on 11 March 2020. In patients undergoing immunotherapy, the effect and path of viral infection remain uncertain. In addition, viral-infected mice and humans show T-cell exhaustion, which is identified after infection with SARS-CoV-2. Read More

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Child restraint system use and its associated factors in Shenzhen.

Accid Anal Prev 2021 Jul 31;160:106321. Epub 2021 Jul 31.

National Center for Chronic and Non-Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China. Electronic address:

Child restraint system (CRS) is effective to protect child passenger safety in a motor vehicle crash. However, research on CRS is limited and the use rate of CRS is not high in China. We carried out a cross-sectional study to examine the use of CRS and its associated factors in Shenzhen. Read More

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MicroRNAs mediated regulation of glutathione peroxidase 7 expression and its changes during adipogenesis.

Biochim Biophys Acta Gene Regul Mech 2021 Jul 30:194734. Epub 2021 Jul 30.

Faculty of Pharmacy in Hradec Králové, Department of Biochemical Sciences, Charles University, Hradec Králové, Czech Republic. Electronic address:

Glutathione peroxidase 7 (GPx7) acts as an intracellular stress sensor/transmitter and plays an important role in adipocyte differentiation and the prevention of obesity related pathologies. For this reason, finding the regulatory mechanisms that control GPx7 expression is of great importance. As microRNAs (miRNAs) could participate in the regulation of GPx7 expression, we studied the inhibition of GPx7 expression by four selected miRNAs with relation to obesity and adipogenesis. Read More

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Transfusion Guidelines in Adult Spine Surgery: A Systematic Review and Critical Summary of Currently Available Evidence.

Spine J 2021 Jul 30. Epub 2021 Jul 30.

University of Texas Southwestern Medical Center, Department of Neurological Surgery, Dallas, TX, USA 75235; University of Texas Southwestern Medical Center, Spine Center, Dallas, TX, USA 75235.

Background Context: Red blood cell transfusion can be associated with complications in medical and surgical patients. Acute anemia in ambulatory patients undergoing surgery can also impede wound healing and independent self-care. Current transfusion threshold guidelines are still based on evidence derived from critically-ill intensive care unit medical patients and may not apply to spine surgery candidates. Read More

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Risk factors for postoperative recurrence of anal fistula identified by an international, evidence-based Delphi consultation survey of surgical specialists.

Int J Surg 2021 Jul 30;92:106038. Epub 2021 Jul 30.

Department of Colorectal Surgery, Changhai Hospital, Second Military Medical University, Shanghai, China. Electronic address:

Background: Despite the emerging knowledge about postoperative anal fistula recurrence (AFR) and the increasing number of clinical studies, there is no better understanding or consensus regarding the risk factors for AFR. The aim of this study was to generate international consensus guidance statements focusing on AFR.

Methods: A two-round modified Delphi process was conducted among international surgical specialists via an online survey delivered by email with a secure link created with Google Forms. Read More

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NRF2 deficiency sensitizes human keratinocytes to zinc oxide nanoparticles-induced autophagy and cytotoxicity.

Environ Toxicol Pharmacol 2021 Jul 30:103721. Epub 2021 Jul 30.

Center for Disease Control and Prevention, Chinese PLA, No. 20 Dongdajie Street, Fengtai area, Beijing, 100071, China; School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang North New area, Shenyang, 110122, China. Electronic address:

Zinc oxide nanoparticles (ZnO NPs) are one of the most commonly used metal oxide particles in many industrial fields. Many studies have shown that ZnO NPs induce harmful effects to human skin, but the mechanisms remain poorly understood. Our results showed that ZnO NPs concentration-dependently induced cytotoxicity, ROS accumulation, and mitochondrial dysfunction in HaCaT cells. Read More

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Cross-national trends of chronic back pain in adolescents: results from the HBSC study, 2001-2014.

J Pain 2021 Jul 30. Epub 2021 Jul 30.

Universitat Rovira i Virgili, Unit for the Study and Treatment of Pain - ALGOS, Research Center for Behavior Assessment (CRAMC), Department of Psychology, Catalonia, Spain; Institut d'Investigació Sanitària Pere Virgili; Universitat Rovira i Virgili, Catalonia, Spain. Electronic address:

Chronic back pain is a common problem that negatively impacts the wellbeing of many adolescents. Prior research suggests that the prevalence of chronic back pain has increased over the last decades, but research on this issue is scarce, single country-based, and has yielded inconsistent results. This study aimed to examine trends in the prevalence of chronic back pain over time in adolescents aged 11, 13 and 15, using data from the Health Behavior in School-aged Children (HBSC) survey. Read More

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Proneurogenic and neuroprotective effect of a multi strain probiotic mixture in a mouse model of acute inflammation: involvement of the gut-brain axis.

Pharmacol Res 2021 Jul 30:105795. Epub 2021 Jul 30.

Institute of Biochemistry and Cell Biology, IBBC, CNR, Monterotondo, Rome, Italy. Electronic address:

Neuroinflammation can severely affect brain homeostasis and adult hippocampal neurogenesis with detrimental effects on cognitive processes. Brain and gut are intimately connected via the "gut-brain axis", a bidirectional communication system, and the administration of live bacteria (probiotics) has been shown to represent an intriguing approach for the prevention or even the cure of several diseases. In the present study we evaluated the putative neuroprotective effect of 15-days consumption of a multi-strain probiotic formulation based on food-associated strains and human gut bacteria at the dose of 10 CFU/mouse/day in a mouse model of acute inflammation, induced by an intraperitoneal single injection of LPS (0. Read More

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Expression profile of long non-coding RNAs in porcine lymphnode response to porcine circovirus type 2 infection.

Microb Pathog 2021 Jul 30:105118. Epub 2021 Jul 30.

Key Laboratory of Prevention and Control Agents for Animal Bacteriosis, Ministry of Agriculture and Rural Affairs; Institute of Animal Husbandry and Veterinary, Hubei Academy of Agricultural Sciences, Wuhan, 430064, PR China. Electronic address:

Porcine circovirus type 2 (PCV2) can cause various clinical diseases in pigs, resulting in huge losses for the pig farms all over the world. In order to develop a new strategy to control PCV2, it is essential to understand its mechanisms firstly, especially PCV2 interferes with the host's innate immunity. In the present study, lncRNA and mRNA expression profiles in porcine lymphnode response to PCV2 infection were deeply sequenced and analyzed. Read More

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A monoclonal antibody neutralizes pesudorabies virus by blocking gD binding to the receptor nectin-1.

Int J Biol Macromol 2021 Jul 30. Epub 2021 Jul 30.

Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China; School of Life Sciences, Zhengzhou University, Zhengzhou, China; College of Veterinary Medicine, Northwest A&F University, Yangling, China; Henan Zhongze Biological Engineering Co., Ltd, Zhengzhou, China; College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou, China; Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Disease and Zoonose, Yangzhou University, Yangzhou, China. Electronic address:

Pseudorabies virus (PRV) was isolated from some human cases recently and the infected patients manifested respiratory dysfunction and acute neurological symptoms. However, no effective drug or vaccine, preventing the progression of PRV infection, is available. Nectin-1 was the only reported receptor for PRV cell entry both swine and human origin, representing an excellent target to block PRV infection, and especially its transmission from pigs to humans. Read More

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Prevention of NAFLD-associated HCC: role of lifestyle and chemoprevention.

J Hepatol 2021 Jul 30. Epub 2021 Jul 30.

University Clinic for Visceral Surgery and Medicine, Inselspital Bern, Bern, Switzerland.

In many countries worldwide, the burden of hepatocellular carcinoma (HCC) in non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) is increasing and preventive strategies are needed to counteract this trend. This review provides an overview of the evidence on preventive strategies in NAFLD-associated HCC. We considered the impact of lifestyle factors such as weight loss, physical activity, smoking, dietary patterns and food items, including coffee and alcohol, on both HCC and NAFLD/NASH. Read More

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Autism spectrum disorder: trace elements imbalances and the pathogenesis and severity of autistic symptoms.

Neurosci Biobehav Rev 2021 Jul 30. Epub 2021 Jul 30.

Chair and 1st Department of Psychiatry, Psychotherapy and Early Intervention, Medical University of Lublin, Gluska Street 1, 20-439, Lublin, Poland; Department of Clinical Neuropsychiatry, Medical University of Lublin, Gluska Street 1, 20-439, Lublin, Poland.

The identification of biomarkers as diagnostic tools and predictors of response to treatment of neurological developmental disorders (NDD) such as schizophrenia (SZ), attention deficit hyperactivity disorder (ADHD), or autism spectrum disorder (ASD), still remains an important challenge for clinical medicine. Metallomic profiles of ASD patients cover, besides essential elements such as cobalt, chromium, copper, iron, manganese, molybdenum, zinc, selenium, also toxic metals burden of: aluminum, arsenic, mercury, lead, beryllium, nickel, cadmium. Performed studies indicate that children with ASD present a reduced ability of eliminating toxic metals, which leads to these metals' accumulation and aggravation of autistic symptoms. Read More

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Environmentally benign Prosopis juliflora extract for corrosion protection by sorption - Gravimetric, mechanistic and thermodynamic studies.

Environ Res 2021 Jul 30:111816. Epub 2021 Jul 30.

Department of Chemical Engineering, Annamalai University, Annamalai Nagar, PC -608002, India.

Environmentally benign plant extract compounds have gained significant attention in the corrosion prevention applications due to their biodegradability and eco-friendliness. The adsorptive corrosion control action of Prosopis juliflora plant extract was investigated using differential mass change experiments and the mechanism was validated using Tafel and Nyquist plots. The effect of green corrosion inhibitor concentration (0-800 ppm) on corrosion rate at different solution temperatures (305. Read More

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Implementing a Maternal Rest Bundle to Prevent Newborn Falls.

J Obstet Gynecol Neonatal Nurs 2021 Jul 30. Epub 2021 Jul 30.

Objective: The specific aims of this quality improvement project were to (a) examine the demographics of newborns who fell and their mothers, (b) implement a maternal rest bundle, and (c) decrease the total number of newborn falls to zero events within 3 months.

Design: We used a quality improvement project with a pre-/postintervention design.

Setting/local Problem: Nine newborn falls occurred over 3. Read More

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Advancing anal cancer prevention in men.

Lancet HIV 2021 Jul 30. Epub 2021 Jul 30.

British Columbia Centre for Disease Control, Vancouver, BC, Canada; University of British Columbia, Vancouver, BC, Canada.

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Epidemiology of anal human papillomavirus infection and high-grade squamous intraepithelial lesions in 29 900 men according to HIV status, sexuality, and age: a collaborative pooled analysis of 64 studies.

Lancet HIV 2021 Jul 30. Epub 2021 Jul 30.

Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

Background: Robust age-specific estimates of anal human papillomavirus (HPV) and high-grade squamous intraepithelial lesions (HSIL) in men can inform anal cancer prevention efforts. We aimed to evaluate the age-specific prevalence of anal HPV, HSIL, and their combination, in men, stratified by HIV status and sexuality.

Methods: We did a systematic review for studies on anal HPV infection in men and a pooled analysis of individual-level data from eligible studies across four groups: HIV-positive men who have sex with men (MSM), HIV-negative MSM, HIV-positive men who have sex with women (MSW), and HIV-negative MSW. Read More

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Microstructured Surfaces for Reducing Chances of Fomite Transmission via Virus-Containing Respiratory Droplets.

ACS Nano 2021 Aug 2. Epub 2021 Aug 2.

Department of Mechanical Engineering, Changwon National University, Changwon 51140, South Korea.

Evaporation-induced particle aggregation in drying droplets is of significant importance in the prevention of pathogen transfer due to the possibility of indirect fomite transmission of the infectious virus particles. In this study, particle aggregation was directionally controlled using contact line dynamics (pinned or slipping) and geometrical gradients on microstructured surfaces by the systematic investigation of the evaporation process on sessile droplets and sprayed microdroplets laden with virus-simulant nanoparticles. Using this mechanism, we designed robust particle capture surfaces by significantly inhibiting the contact transfer of particles from fomite surfaces. Read More

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Testing the content for a targeted age-relevant intervention to promote cervical screening uptake in women aged 50-64 years.

Br J Health Psychol 2021 Aug 2. Epub 2021 Aug 2.

Cancer Prevention Group, School of Cancer and Pharmaceutical Sciences, King's College London, UK.

Objectives: Low uptake of cervical screening in women in their 50s and 60s leaves them at elevated risk of cancer in older age. An age-targeted intervention could be an effective way to motivate older women to attend cervical screening. Our primary objective was to test the impact of different candidate messages on cervical screening intention strength. Read More

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Exceptional life-threatening complication 19 years after Ravitch correction of pectus excavatum.

J Card Surg 2021 Aug 2. Epub 2021 Aug 2.

Department of Cardiac Surgery, J Strus Multidisciplinary Hospital, Poznan, Poland.

Background: Ravitch technique of chest correction has been considered, although invasive, as a safe and efficacious surgical method.

Case: We describe a case of a 35-year-old woman with cardiac tamponade and in cardiogenic shock due to exceptional late complication after pectus excavatum reconstruction by means of classic Ravitch technique 19 years earlier. This very late adverse event was caused by a broken metal sternal wire that injured the wall of the ascending aorta. Read More

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Variability of discharge medical therapy for secondary prevention among patients with myocardial infarction with non-obstructive coronary arteries (MINOCA) in the United States.

PLoS One 2021 2;16(8):e0255462. Epub 2021 Aug 2.

Leon H. Charney Division of Cardiology, Department of Medicine, Soter Center for Women's Cardiovascular Research, New York University School of Medicine, New York, NY, United States of America.

Background: Optimal medical therapy after myocardial infarction with nonobstructive coronary arteries (MINOCA; <50% stenosis) is uncertain. We evaluated variability in discharge prescription of angiotensin-converting enzyme inhibitors / angiotensin receptor blockers (ACEI/ARB) and beta-blockers (BB) to MINOCA patients between hospitals to assess physician equipoise about secondary prevention.

Methods: Patients with MINOCA between 2007-2014 were identified in the NCDR Chest Pain-MI Registry. Read More

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Association between serum iron concentrations and cognitive impairment in older adults aged 60 years and older: A dose-response analysis of National Health and Nutrition Examination Survey.

PLoS One 2021 2;16(8):e0255595. Epub 2021 Aug 2.

Department of Integrated Services, Kunshan Centers for Disease Control and Prevention, Kunshan, Jiangsu, China.

Epidemiological evidence on peripheral iron and cognitive impairment in older adults is sparse and limited. Results on serum iron and cognitive impairment in older adults from the National Health and Nutrition Examination Survey have not been reported. Data on serum iron and cognitive impairment from individuals ≥ 60 years of age were obtained from the 2011-2014 NHANES (N = 3,131). Read More

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Spatial-temporal heterogeneity and meteorological factors of hand-foot-and-mouth disease in Xinjiang, China from 2008 to 2016.

PLoS One 2021 2;16(8):e0255222. Epub 2021 Aug 2.

Faculty of Geographical Science, Beijing Normal University, Beijing, China.

The study aims to depict the temporal and spatial distributions of hand-foot-and-mouth disease (HFMD) in Xinjiang, China and reveal the relationships between the incidence of HFMD and meteorological factors in Xinjiang. With the national surveillance data of HFMD in Xinjiang and meteorological parameters in the study area from 2008 to 2016, in GeoDetector Model, we examined the effects of meteorological factors on the incidence of HFMD in Xinjiang, China, tested the spatial-temporal heterogeneity of HFMD risk, and explored the temporal-spatial patterns of HFMD through the spatial autocorrelation analysis. From 2008 to 2016, the HFMD distribution showed a distinct seasonal pattern and HFMD cases typically occurred from May to July and peaked in June in Xinjiang. Read More

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