154 results match your criteria prevent cvi


Association between cholesterol efflux capacity and peripheral artery disease in coronary heart disease patients with and without type 2 diabetes: from the CORDIOPREV study.

Cardiovasc Diabetol 2021 Mar 25;20(1):72. Epub 2021 Mar 25.

Lipids and Atherosclerosis Unit. Servicio de Medicina Interna, Reina Sofia University Hospital, Maimonides Institute for Biomedical Research in Córdoba, University of Córdoba, Córdoba, Spain.

Background: Peripheral artery disease (PAD) is recognized as a significant predictor of mortality and adverse cardiovascular outcomes in patients with coronary heart disease (CHD). In fact, coexisting PAD and CHD is strongly associated with a greater coronary event recurrence compared with either one of them alone. High-density lipoprotein (HDL)-mediated cholesterol efflux capacity (CEC) is found to be inversely associated with an increased risk of incident CHD. Read More

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Construction and validation of educational technology to prevent complications in intestinal ostomies / periestomy skin.

Rev Bras Enferm 2020 21;73(suppl 5):e20190825. Epub 2020 Dec 21.

Universidade Regional do Cariri. Crato, Ceará, Brazil.

Objective: To build and validate an educational booklet for preventing complications in intestinal ostomy and peristomy skin.

Methods: Methodological study developed in: 1. Survey of the clinical profile of patients; 2. Read More

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December 2020

Building and validating an educational video for elderly individuals about fall risks.

Rev Bras Enferm 2020 23;73(suppl 3):e20200010. Epub 2020 Oct 23.

Universidade Federal do Piauí. Teresina. Piauí. Brazil.

Objective: to build and validate educational video for elderly individuals about fall risks.

Methods: methodological study with video building. validated by 22 judges and assessed by 22 elderly individuals. Read More

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October 2020

A Diet-Dependent Microbiota Profile Associated with Incident Type 2 Diabetes: From the CORDIOPREV Study.

Mol Nutr Food Res 2020 Oct 16:e2000730. Epub 2020 Oct 16.

Lipids and Atherosclerosis Research Unit, Internal Medicine Unit, Reina Sofia University Hospital, Cordoba, 14004, Spain.

Scope: The differences between the baseline gut microbiota of patients who developed type 2 diabetes (T2D) consuming a low-fat (LF) or a Mediterranean (Med) diet are explored and risk scores are developed to predict the individual risk of developing T2D associated with the consumption of LF or Med diet.

Methods And Results: All the patients from the CORDIOPREV study without T2D at baseline (n = 462) whose fecal sample are available, are included. Gut microbiota is analyzed by 16S sequencing and the risk of T2D after a median follow-up of 60 months assessed by Cox analysis. Read More

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October 2020

Validation of an instrument to measure adherence to type 2 diabetes management.

Int J Clin Pharm 2020 Oct 7. Epub 2020 Oct 7.

Departamento de Medicina y Nutrición, Universidad de Guanajuato, Blvd. Puente del Milenio 1001, San Carlos, CP. 37672, León, Gto, Mexico.

Background Adherence to type 2 diabetes management is defined as the extent to which the behaviour of a person matches the one recommended by health care professionals. Control of this disease depends on adherence to diabetes management, which includes monitoring blood glucose levels, adopting a healthy diet, exercising, taking medication, quitting smoking, and undergoing psychosocial care and periodic check-ups. This can also prevent health complications and reduce medical costs. Read More

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October 2020

Knowledge, attitude, and practice among staff associated with Human Papillomavirus Vaccine of young children in Iran.

Med J Malaysia 2020 09;75(5):543-547

IAU (Islamic Azad University), Management Dept., North Tehran Branch, Tehran, Iran.

Introduction: This study aimed to evaluate knowledge, attitudes, practice associated with Human Papillomavirus (HPV) Vaccine for Young Children among lecturers and health staffs of Shahid Beheshti University of Medical Sciences (SBMU).

Method: This was a cross-sectional study with 220 adults from five different specialties, randomly selected. Data was collected using 45-item questionnaire on knowledge (12- item), attitude (18-item) and practice (15-item) (KAP) about HPV. Read More

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September 2020

Stability of complete blood count parameters depends on the storage temperature, storage time, transport position and selected stability criterion.

Scand J Clin Lab Invest 2020 Oct 28;80(6):470-478. Epub 2020 Jun 28.

Department of Medical Biochemistry, Hitit University School of Medicine, Corum, Turkey.

: To evaluate stability of CBC parameters in samples containing K-EDTA in Hema&Tube brand evacuated tubes stored at 4 °C and room temperature in upright, horizontal and upside-down transport positions for up to 240 min by comparing with different stability criteria. : A total of 450 outpatient samples, 75 for each condition, were stored for 240 min. Blood samples were analyzed at baseline, 60th, 120th and 240th min of storage time using Sysmex® XT-4000i hematology analyzer. Read More

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October 2020

Skin disorders indicating peripheral arterial occlusive disease and chronic venous insufficiency in organ transplant recipients.

J Diabetes Complications 2020 09 15;34(9):107623. Epub 2020 May 15.

Department of Dermatology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, the Netherlands. Electronic address:

Background: Peripheral arterial occlusive disease (PAOD) and chronic venous insufficiency (CVI) in organ transplant recipients (OTR) can lead to harmful outcomes. We made an inventory of cutaneous manifestations of PAOD and CVI in OTR in relation with diabetes and other potential risk factors.

Methods: A prospective study in a single center was performed. Read More

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September 2020

Association between bisoprolol plasma concentration and worsening of heart failure: (CVI ARO 6).

Drug Metab Pharmacokinet 2020 Apr 13;35(2):228-237. Epub 2020 Jan 13.

Department of Cardiovascular Medicine, The Cardiovascular Institute, Tokyo, Japan.

Background: Although bisoprolol has been established to prevent heart failure (HF), finding the optimal dose remains a challenge. It is crucial to understand the distribution of bisoprolol plasma concentration (Bis-PC) and association with outcomes.

Methods: This was a single-center observational study in 114 HF patients under once-daily bisoprolol. Read More

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Using compression therapy in a primary care setting to treat complications of chronic venous insufficiency.

J Am Assoc Nurse Pract 2019 Dec 19. Epub 2019 Dec 19.

Capstone College of Nursing at The University of Alabama, Tuscaloosa, Alabama.

Background: Patients with chronic venous insufficiency (CVI) are prone to developing complications such as slow-healing venous leg ulcers.

Local Problem: Nurse practitioners can assess patients for complications of CVI during routine examinations. If found, they can implement compression therapy and possibly prevent the development of slow-healing venous leg ulcers. Read More

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December 2019

Chronic venous insufficiency: A review for nurses.

Nursing 2019 Dec;49(12):24-30

Linda Berti-Hearn is a certified wound, ostomy, and continence nurse at Virtua Health, Home Health Division, in Mt. Laurel, N.J. Brenda Elliott is an adjunct professor at Wilson College (Division of Nursing and Health Sciences) in Chambersburg, Pa.

Chronic venous insufficiency (CVI) is a potentially debilitating disorder associated with serious complications such as lower extremity venous ulcers. This article reviews the incidence and pathophysiology of CVI, nursing assessment, diagnosis and interventions, and patient education needed to manage the disease and prevent complications. Read More

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December 2019

Continence App: Construction and validation of a mobile application for postnatal urinary incontinence prevention.

Eur J Obstet Gynecol Reprod Biol 2019 Sep 27;240:330-335. Epub 2019 Jul 27.

Nursing Department, Campinas State University, Campinas, São Paulo, Brazil.

Objective: Describing the Continence App development as an educational technology to promote adherence to pelvic floor muscle training and prevent urinary incontinence in postpartum women.

Study Design: Study of technological production carried out in two stages: construction and validation. The first happened in four steps: modeling, navigation project, abstract design of the interface and implementation. Read More

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September 2019

Pressure Ulcer Prevention Care Bundle: A Cross-sectional, Content Validation Study.

Wound Manag Prev 2019 05;65(5):33-39

Ankara Yildirim Beyazit University Faculty of Health Sciences, Department of Nursing, Ankara, Turkey.

A care bundle is an organized set of interventions that encourages compliance with guidelines designed to improve quality of care.

Purpose: This study was conducted to determine the content validity of a previously developed pressure ulcer prevention care bundle.

Methods: A cross-sectional study was performed in a university hospital in Turkey among 95 nurses employed in 8 intensive care units (ICUs) who were invited to use and assess a care bundle based on pressure ulcer guidelines found in the literature and developed by researchers. Read More

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Ankle joint mobility as a predictor of treatment prognosis in patients with chronic venous insufficiency with venous ulcers.

J Vasc Bras 2019 Jun 25;18:e20180133. Epub 2019 Jun 25.

Hospital Universitário Regional dos Campos Gerais - HURCG, Cirurgia Geral, Ponta Grossa, PR, Brasil.

The present study arose from the need to improve treatment of patients with chronic venous insufficiency (CVI) who present with venous ulcers. A total of 40 lower limbs were assessed from 20 patients with healed venous ulcers (C5) or active venous ulcers (C6) who had undergone varicose vein surgery. The relationship between the range of motion of the ankle joint and presence of C5 or C6 venous ulcer was analyzed. Read More

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Development and Validation of the Just Culture Assessment Tool for Nursing Education.

Nurse Educ 2019 Sep/Oct;44(5):261-264

Author Affiliations: Assistant Professor (Dr Walker), Harris College of Nursing and Health Sciences, Texas Christian University, Fort Worth; Professor (Dr Altmiller); School of Nursing, Health, and Exercise Science, The College of New Jersey, Ewing; Faculty (Ms Barkell), Nursing, Oakland Community College, Waterford, Michigan; Associate Professor (Dr Hromadik), Department of Nursing and Allied Health Professions, Indiana University of Pennsylvania; Assistant Professor (Dr Toothaker), Department of Nursing, Bloomsburg University, Pennsylvania.

Background: Patient safety efforts in practice have focused on creating a just culture where errors can be identified and reported, and system remedies created to prevent reoccurrence. The same is not true of nursing education where student experiences with error and the sequelae that follow focus on individual performance.

Purpose: The purpose of this study was to adapt the Just Culture Assessment Tool (JCAT) used in practice settings into a valid and reliable instrument to evaluate just culture in academic settings. Read More

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December 2019

Rehabilitation technology for self-care: Customised foot and ankle exercise software for people with diabetes.

PLoS One 2019 20;14(6):e0218560. Epub 2019 Jun 20.

Departamento Fisioterapia, Fonoaudiologia e Terapia Ocupacional, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, São Paulo, Brazil.

Aims: To develop and validate the content of a free web-based software (desktop and mobile applications) for the self-management of and customised foot-ankle exercises for people with diabetes and diabetic neuropathy.

Methods: The development of the programme was based on gamification principles and addressed three main areas: foot care recommendations; self-assessment of feet according to the main complications of diabetic neuropathy; and customised foot-ankle exercises to strengthen muscles, increase the range of motion and improve functionality. The content was validated using the Delphi methodology and a quantitative approach in two rounds with diabetes specialists (n = 9) and users with diabetes (n = 20). Read More

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February 2020

The Self-Management Assessment Scale: Development and psychometric testing of a screening instrument for person-centred guidance and self-management support.

Nurs Open 2019 Apr 26;6(2):504-513. Epub 2018 Dec 26.

Department of Nursing Umeå University Umeå Sweden.

Aim: To develop and psychometrically test the Self-Management Assessment Scale (SMASc), a screening instrument for person-centred guidance and self-management support of persons with type 2 diabetes (T2D).

Background: T2D is a common and globally increasing chronic condition. Improved self-management is a vital and integral component of diabetes care to prevent complications from poorly managed diabetes. Read More

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Validation of a Norwegian version of SURgical PAtient Safety System (SURPASS) in combination with the World Health Organizations' Surgical Safety Checklist (WHO SSC).

BMJ Open Qual 2019 7;8(1):e000488. Epub 2019 Jan 7.

Department of Anaesthesia and Intensive Care, Haukeland University Hospital, Bergen, Norway.

Introduction: Surgical safety checklists may contribute to reduction of complications and mortality. The WHO's Surgical Safety Checklist (WHO SSC) could prevent incidents in operating theatres, but errors also occur before and after surgery. The SURgical PAtient Safety System (SURPASS) is designed to intercept errors with use of checklists throughout the surgical pathway. Read More

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Mobile persuasive technology for the teaching and learning in surgical safety: Content validation.

Nurse Educ Today 2018 Dec 29;71:129-134. Epub 2018 Sep 29.

Medicine A&M Health Science Center, TX, United States. Electronic address:

Background: Patient safety is a fundamental component of high-quality delivery of health care. However, despite scientific advances, surgical patients continue to face risks. Among the most common complications in surgery are operations on the wrong patient, performance of the wrong procedure or operation on the wrong surgical site, lack of adequate or required equipment, failure to prevent blood loss, and surgical items left inside patients. Read More

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December 2018

Influence of Diosmin Treatment on the Level of Oxidative Stress Markers in Patients with Chronic Venous Insufficiency.

Oxid Med Cell Longev 2018 28;2018:2561705. Epub 2018 Aug 28.

Chair and Department of Biology and Genetics, Medical University of Lublin, W. Chodźki 4A, 20-093 Lublin, Poland.

Oxidative stress plays an important role in the pathophysiology of many human disorders, while antioxidants prevent the development of various adverse symptoms. Diosmin is a natural flavonoid applied in vascular system disorders, especially in chronic venous insufficiency (CVI), and it plays a significant part in the alleviation of CVI symptoms. Due to antioxidant activity, it also has the ability to scavenge the oxygen free radicals and hence decreases the level of oxidative stress biomarkers, such as prostaglandins and their precursors-isoprostanes. Read More

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November 2018

Development and Validity Testing of an Assessment Tool for Domestic Elder Abuse.

J Nurs Res 2019 Apr;27(2):e12

PhD, RN, CTN-A, Lecturer, Division of Family Health Care Nursing, Department of Nursing, Graduate School of Health Sciences, Kobe University, Japan.

Background: The older adult population is increasing in number, and elder abuse is expected to become a more pressing problem. Developing tools to assess the presence and severity of elder abuse is important to both effectively prevent this abuse and provide increased support for families.

Purpose: This study was intended to test the validity of an Assessment Tool for Domestic Elder Abuse (ATDEA). Read More

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Validation of primer for promoting maternal self-efficacy in preventing childhood diarrhea.

Rev Bras Enferm 2018 ;71(suppl 3):1412-1419

Universidade Federal do Ceará. Fortaleza, Ceará, Brasil.

Objective: to validate an educational primer, regarding content and design, for promoting maternal self-efficacy in preventing childhood diarrhea.

Method: methodological study composed of 31 mothers of children under five years of age, in which the validation of the primer You can prevent diarrhea in your child! was carried out from the Content Validity Index (CVI), being evaluated as to the domains understanding, attractiveness, self-efficacy, cultural acceptance, and persuasion.

Results: the primer was considered relevant and clear, with average concordance of 99. Read More

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January 2019

Progress toward Development of a Vaccine against Congenital Cytomegalovirus Infection.

Clin Vaccine Immunol 2017 Dec 5;24(12). Epub 2017 Dec 5.

University of Pennsylvania, Vaxconsult, Philadelphia, Pennsylvania, USA.

A vaccine against congenital human cytomegalovirus (CMV) infection is a major public health priority. Congenital CMV causes substantial long-term morbidity, particularly sensorineural hearing loss (SNHL), in newborns, and the public health impact of this infection on maternal and child health is underrecognized. Although progress toward development of a vaccine has been limited by an incomplete understanding of the correlates of protective immunity for the fetus, knowledge about some of the key components of the maternal immune response necessary for preventing transplacental transmission is accumulating. Read More

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December 2017

Treatment in the home setting with intermittent pneumatic compression for a woman with chronic leg ulcers: a case report.

BMC Nurs 2017 21;16:56. Epub 2017 Sep 21.

School of Nursing and Midwifery, Western Sydney University/Nepean Blue Mountains Local Health District, Sydney, Australia.

Background: Intermittent Pneumatic Compression (IPC) is shown to improve the healing rate of Venous Leg Ulcers (VLU) in the hospital setting. The current Australian "Gold Standard" treatment according to the Australian and New Zealand Wound Management Associations' (AWMA) Prevention & Management of Venous Leg Ulcer guidelines is compression, generally in the form of bandaging then progressing to hosiery once wounds are healed to prevent recurrence. This is recommended in conjunction with other standards of wound management including; nutrition, exercise, client education and addressing underlying pathophysiology and psychosocial factors. Read More

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September 2017

Chronic Venous Insufficiency: a Frequently Underdiagnosed and Undertreated Pathology.

Maedica (Bucur) 2017 Jan;12(1):59-61

Department of Internal Medicine, "St. Spiridon" Clinical Emergency Hospital, Iasi, Romania.

The article describes the medical approach of a frequent pathology, chronic venous insufficiency. Chronic venous insufficiency requires early diagnosis as well as an evaluation of the associated risk factors; also, patients need to understand the disease and its treatment, and to become compliant with all their physician's recommendations. Importantly, the physician should correctly evaluate the disease and decide the best option for the patient. Read More

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January 2017

A Cation-Binding Surface Protein as a Vaccine Antigen To Prevent Moraxella catarrhalis Otitis Media and Infections in Chronic Obstructive Pulmonary Disease.

Clin Vaccine Immunol 2017 Sep 5;24(9). Epub 2017 Sep 5.

Department of Structural Biology, University at Buffalo, the State University of New York, Buffalo, New York, USA.

is an exclusively human respiratory tract pathogen that is a common cause of otitis media in children and respiratory tract infections in adults with chronic obstructive pulmonary disease. A vaccine to prevent these infections would have a major impact on reducing the substantial global morbidity and mortality in these populations. Through a genome mining approach, we identified AfeA, an ∼32-kDa substrate binding protein of an ABC transport system, as an excellent candidate vaccine antigen. Read More

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September 2017

Conjugation of PspA4Pro with Capsular Streptococcus pneumoniae Polysaccharide Serotype 14 Does Not Reduce the Induction of Cross-Reactive Antibodies.

Clin Vaccine Immunol 2017 Aug 4;24(8). Epub 2017 Aug 4.

Laboratório Especial de Desenvolvimento de Vacinas, Instituto Butantan, São Paulo, Brazil

Current pneumococcal vaccines are composed of bacterial polysaccharides as antigens, plain or conjugated to carrier proteins. While efficacious against vaccine serotypes, epidemiologic data show an increasing incidence of infections caused by nonvaccine serotypes of The use of pneumococcal surface protein A (PspA) as a carrier protein in a conjugate vaccine could help prevent serotype replacement by increasing vaccine coverage and reducing selective pressure of serotypes. PspA is present in all pneumococcal strains, is highly immunogenic, and is known to induce protective antibodies. Read More

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Cytomegalovirus Virions Shed in Urine Have a Reversible Block to Epithelial Cell Entry and Are Highly Resistant to Antibody Neutralization.

Clin Vaccine Immunol 2017 Jun 5;24(6). Epub 2017 Jun 5.

Virginia Commonwealth University, Richmond, Virginia, USA

Cytomegalovirus (CMV) causes sensorineural hearing loss and developmental disabilities in newborns when infections are acquired Pregnant women may acquire CMV from oral exposure to CMV in urine or saliva from young children. Neutralizing antibodies in maternal saliva have the potential to prevent maternal infection and, in turn, fetal infection. As CMV uses different viral glycoprotein complexes to enter different cell types, the first cells to be infected in the oral cavity could determine the type of antibodies needed to disrupt oral transmission. Read More

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Transcutaneous Immunization with a Band-Aid Prevents Experimental Otitis Media in a Polymicrobial Model.

Clin Vaccine Immunol 2017 Jun 5;24(6). Epub 2017 Jun 5.

Center for Microbial Pathogenesis, The Research Institute at Nationwide Children's and The Ohio State University College of Medicine, Columbus, Ohio, USA

Otitis media (OM) is a common pediatric disease, and nontypeable (NTHI) is the predominant pathogen in chronic OM, recurrent OM, and OM associated with treatment failure. OM is also a polymicrobial disease, wherein an upper respiratory tract viral infection predisposes to ascension of NTHI from the nasopharynx, the site of colonization, to the normally sterile middle ear, resulting in disease. Using a clinically relevant viral-bacterial coinfection model of NTHI-induced OM, we performed transcutaneous immunization (TCI) via a band-aid delivery system to administer each of three promising NTHI vaccine candidates derived from bacterial adhesive proteins and biofilm mediators: recombinant soluble PilA (rsPilA), chimV4, and integration host factor. Read More

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Plasmablast Response to Primary Rhesus Cytomegalovirus (CMV) Infection in a Monkey Model of Congenital CMV Transmission.

Clin Vaccine Immunol 2017 May 5;24(5). Epub 2017 May 5.

Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, USA

Human cytomegalovirus (HCMV) is the most common congenital infection worldwide and the leading infectious cause of neurologic deficits and hearing loss in newborns. Development of a maternal HCMV vaccine to prevent vertical virus transmission is a high priority, yet protective maternal immune responses following acute infection are poorly understood. To characterize the maternal humoral immune response to primary CMV infection, we investigated the plasmablast and early antibody repertoire using a nonhuman primate model with two acutely rhesus CMV (RhCMV)-infected animals-a CD4 T cell-depleted dam that experienced fetal loss shortly after vertical RhCMV transmission and an immunocompetent dam that did not transmit RhCMV to her infant. Read More

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