AIDS 2021 Jun 24. Epub 2021 Jun 24.
Department of Epidemiology, University of Washington, Seattle, USA Department of Global Health, University of Washington, Seattle, USA Kenya Medical Research Institute, Nairobi, Kenya Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, USA Department of Biostatistics, University of Washington, Seattle, USA Clinical Trials Research Centre, University of Zimbabwe, Harare, Zimbabwe College of Health Sciences, University of Zimbabwe Department of Medicine/Division of Infectious Diseases, University of Alabama at Birmingham, Alabama, USA Kaiser Permanente Washington Health Research Institute, Seattle, USA Centre for the AIDS Programme of Research in South Africa, University of KwaZulu-Natal, Durban, South Africa Wits Reproductive Health and HIV Institute in Johannesburg, South Africa Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa South Africa Medical Research Council, Durban, South Africa Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa The Aurum Institute, Klerksdorp, South Africa Makerere University-John Hopkins University Research Collaboration Perinatal HIV Research Unit, Chris Hani Baragwanath Hospital, Soweto, South Africa Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, USA Department of Obstetrics and Gynecology, University of Washington, Seattle, USA.
Objective: Vaccine-preventable human papillomavirus (HPV) infection is common, especially in sub-Saharan Africa where HIV risk is also high. However, unlike other sexually transmitted infections (STIs), HPV's role in HIV acquisition is unclear. We evaluated this relationship using data from MTN-003, a clinical trial of HIV chemoprophylaxis among cisgender women in sub-Saharan Africa. Read More