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Characterization of Essential Oils from Different Taxa Belonging to the Genus in Sardinia Island, Italy.

Plants (Basel) 2021 Jul 2;10(7). Epub 2021 Jul 2.

Co.S.Me.Se, Consorzio per lo Studio dei Metaboliti Secondari, Via Sant'Ignazio da Laconi 13, 09123 Cagliari, Italy.

The genus L. (Lamiaceae) is a genus growing in mild climate zones, particularly in the Mediterranean Basin and Central Asia. It is represented by 11 taxa in Sardinia (Italy), living commonly in sunny habitats. Read More

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Formation of ZrC-SiC Composites from the Molecular Scale through the Synthesis of Multielement Polymers.

Materials (Basel) 2021 Jul 13;14(14). Epub 2021 Jul 13.

Laboratoire de Chimie de la Matière Condensée de Paris, CNRS, Sorbonne Université, LCMCP, F-75005 Paris, France.

In the field of non-oxide ceramic composites, and by using the polymer-derived ceramic route, understanding the relationship between the thermal behaviour of the preceramic polymers and their structure, leading to the mechanisms involved, is crucial. To investigate the role of Zr on the fabrication of ZrC-SiC composites, linear or hyperbranched polycarbosilanes and polyzirconocarbosilanes were synthesised through either "click-chemistry" or hydrosilylation reactions. Then, the thermal behaviours of these polymeric structures were considered, notably to understand the impact of Zr on the thermal path going to the composites. Read More

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Evolution of the fabric of cardiovascular science: Saga of an enduring process of refinement.

Ann Cardiol Angeiol (Paris) 2021 Jul 14. Epub 2021 Jul 14.

Department of Anatomy, All India Institute of Medical Sciences, Phulwarisharif, Patna, Bihar, India.

Background: The core elements of cardiovascular science have been established by scholarly pursuits of numerous scientists across centuries. In this article, we have tried to trace the evolutionary journey of cardiovascular science from a rudimentary form in ancient period to a robust scientific discipline in modern times.

Methods: A literature search of relevant, peer-reviewed, published articles was undertaken from indexed databases (Medline & Pubmed, Scopus, Embase, CINAHL Plus, Web of Science and Google Scholar). Read More

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An investigation of coping in response to different race-related stressor experiences in school among racially diverse participants.

Am J Orthopsychiatry 2021 ;91(2):181-192

Andrew Young Center for Global Leadership, Morehouse College.

The landmark Brown versus Board of Education decision led to the desegregation of public schools in the United States. Consequently, Black/African American, Latinx, Asian, and Native American (BALANA) students experienced multiple race-related stressors. Not surprisingly, BALANA students still report experiences with racial discrimination, exclusion, and harassment in public schools. Read More

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January 2021

Does Abrupt Weight Loss Caused by Bariatric Surgery Compromise the Voice in Women?

J Voice 2021 Apr 5. Epub 2021 Apr 5.

Department of Ophthalmology, Otorhinolaryngology, Head and Neck Surgery, São Paulo State University, Botucatu, SP, Brazil. Electronic address:

Objective: To evaluate vocal symptoms, voice characteristics and videolaryngoscopy in obese women before and after bariatric surgery.

Methods: Obese patients (18 to 59 years old), candidates for bariatric surgery were recruited. Evaluation times: T1 (preoperative), T2 (after six months), T3 (after 12 months). Read More

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The evolution in the surgical management of Peyronie's disease.

Urologia 2021 May 30;88(2):79-89. Epub 2021 Mar 30.

Department of Urology, ASST Fatebenefratelli-Sacco, Luigi Sacco University Hospital, Milan, Italy.

Peyronie's disease (PD) is due to a fibrotic alteration of the tunica albuginea of the penis. It is responsible of penile pain, angulation, and possible erectile dysfunction (ED). Despite almost three centuries have passed since the first description of the disease, etiology still remains uncertain. Read More

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CaMKII and PKA-dependent phosphorylation co-regulate nuclear localization of HDAC4 in adult cardiomyocytes.

Basic Res Cardiol 2021 02 15;116(1):11. Epub 2021 Feb 15.

Department of Pharmacology, University of California, Genome Building Rm 3513, Davis, CA, 95616-8636, USA.

Nuclear histone deacetylase 4 (HDAC4) represses MEF2-mediated transcription, implicated in the development of heart failure. CaMKII-dependent phosphorylation drives nucleus-to-cytoplasm HDAC4 shuttling, but protein kinase A (PKA) is also linked to HDAC4 translocation. However, the interplay of CaMKII and PKA in regulating adult cardiomyocyte HDAC4 translocation is unclear. Read More

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February 2021

Homecare workers in Italy: a narrative review.

Ann Ig 2021 Mar-Apr;33(2):163-176

Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.

Introduction: The progressive ageing and ever-increasing life expectancy of the world's population are accompanied by an increase in chronic pathologies. Italy continues to be the nation with the highest percentage of senior citizens. Recent economic crises and movements of social change have led to a gradual increase in the use of homecare workers for the territorial and family management of chronic illnesses. Read More

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February 2021

Proteome changes in pepper (Capsicum annuum L.) leaves induced by the green peach aphid (Myzus persicae Sulzer).

BMC Plant Biol 2021 Jan 6;21(1):12. Epub 2021 Jan 6.

Unidad Asociada CSIC-UA IPAB. Instituto Universitario de Investigación CIBIO (Centro Iberoamericano de la Biodiversidad), University of Alicante, Carretera de San Vicente del Raspeig, s/n, E-03690 San Vicente del Raspeig, Alicante, Spain.

Background: Aphid attack induces defense responses in plants activating several signaling cascades that led to the production of toxic, repellent or antinutritive compounds and the consequent reorganization of the plant primary metabolism. Pepper (Capsicum annuum L.) leaf proteomic response against Myzus persicae (Sulzer) has been investigated and analyzed by LC-MS/MS coupled with bioinformatics tools. Read More

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January 2021

Reconsidering the evidence for learning in single cells.

Elife 2021 Jan 4;10. Epub 2021 Jan 4.

Department of Systems Biology, Harvard Medical School, Boston, United States.

The question of whether single cells can learn led to much debate in the early 20th century. The view prevailed that they were capable of non-associative learning but not of associative learning, such as Pavlovian conditioning. Experiments indicating the contrary were considered either non-reproducible or subject to more acceptable interpretations. Read More

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January 2021

Lemon juice and apple juice used as source of citrate and malate, respectively, enhance the formation of buttery aroma compounds and/or organic acids during Type 2 and Type 3 sourdough productions performed with Companilactobacillus crustorum LMG 23699.

Int J Food Microbiol 2021 Feb 13;339:109020. Epub 2020 Dec 13.

Research Group of Industrial Microbiology and Food Biotechnology (IMDO), Faculty of Sciences and Bioengineering Sciences, Vrije Universiteit Brussel (VUB), Pleinlaan 2, B-1050 Brussels, Belgium. Electronic address:

Extra ingredients are often used in traditional sourdough production recipes by artisan bakeries. These ingredients may be the source of microorganisms or stimulate the growth and/or the metabolic activities of the microorganisms added to or naturally present in the flour-water mixture. The present study examined the influence of the addition of lemon juice or apple juice as source of citrate or malate, respectively, on the growth and activity of the citrate- and malate-positive Companilactobacillus crustorum LMG 23699 strain (formerly known as Lactobacillus crustorum LMG 23699), used to initiate firm (dough yield of 200) wheat sourdough productions, and on the flavour of the baked goods produced. Read More

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February 2021

Study of Radiation-Induced Defects in -Type SiGe Diodes before and after Annealing.

Materials (Basel) 2020 Dec 12;13(24). Epub 2020 Dec 12.

Institute of Photonics and Nanotechnology, Vilnius University, Sauletekio ave. 3, LT-10257 Vilnius, Lithuania.

In this work, electrically active defects of pristine and 5.5 MeV electron irradiated -type silicon-germanium (SiGe)-based diodes were examined by combining regular capacitance deep-level transient spectroscopy (C-DLTS) and Laplace DLTS (L-DLTS) techniques. The -type SiGe alloys with slightly different Ge contents were examined. Read More

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December 2020

Weather and Aggressive Behavior among Patients in Psychiatric Hospitals-An Exploratory Study.

Int J Environ Res Public Health 2020 12 7;17(23). Epub 2020 Dec 7.

Department of Health Psychology, Faculty of Health Sciences, Institute of Nursing and Midwifery, Jagiellonian University Medical College, 31-501 Kraków, Poland.

The number of meteoropaths, or people negatively affected by weather conditions, is rising dramatically. Meteoropathy is developing rapidly due to ever poorer adaptations of people to changes in weather conditions. Strong weather stimuli may not only exacerbate symptoms in people with diseases of the cardiovascular and respiratory systems but may also induce aggressive behavior. Read More

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December 2020

Overloaded Orthopedic Force Induces Condylar Subchondral Bone Absorption by Stimulating Rat Mesenchymal Stem Cells Differentiating into Osteoclasts via mTOR-Regulated Secretion in Osteoblasts.

Stem Cells Dev 2021 01 15;30(1):29-38. Epub 2020 Dec 15.

Department II of Orthodontics, Affiliated Hospital of Qingdao University, Qingdao, People's Republic of China.

Appropriate orthopedic force led to bone remodeling of mandibular condyle, while overloaded orthopedic force (OOF) induced condylar bone absorption. Bone absorption is ascribed to the imbalanced activities between osteoclasts (OCs) and osteoblasts (OBs), mechanism of which remains unclear. This study aimed to observe the condylar changes induced by OOF by mandible advancement appliance and to further investigate the role of mammalian target of Rapamycin () and in osteoclastic differentiation of stem cells in vivo and in vitro. Read More

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January 2021

Early epidemiological indicators, outcomes, and interventions of COVID-19 pandemic: A systematic review.

J Glob Health 2020 Dec;10(2):020506

Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, USA.

Background: Coronavirus disease-2019 (COVID-19), a pandemic that brought the whole world to a standstill, has led to financial and health care burden. We aimed to evaluate epidemiological characteristics, needs of resources, outcomes, and global burden of the disease.

Methods: Systematic review was performed searching PubMed from December 1, 2019, to March 25, 2020, for full-text observational studies that described epidemiological characteristics, following MOOSE protocol. Read More

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December 2020


Georgian Med News 2020 Jul-Aug(304-305):135-141

2National University of Pharmacy, Kharkiv, Ukraine.

The purpose of this scientific work was to investigate the development of puberty in females-offspring born to mothers of different age with fetoplacental insufficiency (FPI) and to evaluate efficacy of base and combined drug therapy during pregnancy. Negative influence of FPI on the puberty genesis of females-offspring born to mothers of different reproductive age is considered to be the results of the investigation. In particular, the increased anogenital distance, which is the sign of estrogen deficiency, has been observed in females-offspring born to reproductively young mothers with FPI. Read More

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September 2020

Reviving material theories of induction.

John P McCaskey

Stud Hist Philos Sci 2020 Oct 11;83:1-7. Epub 2020 Jan 11.

Fordham University, USA. Electronic address:

John Norton says that philosophers have been led astray for thousands of years by their attempt to treat induction formally. He is correct that such an attempt has caused no end of trouble, but he is wrong about the history. There is a rich tradition of non-formal induction. Read More

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October 2020

Electrospun Composites Made of Reduced Graphene Oxide and Polyacrylonitrile-Based Activated Carbon Nanofibers (rGO/ACNF) for Enhanced CO Adsorption.

Polymers (Basel) 2020 Sep 17;12(9). Epub 2020 Sep 17.

Advanced Membrane Technology Research Centre (AMTEC), School of Chemical and Energy Engineering, Faculty of Engineering, Universiti Teknologi Malaysia, Johor Bahru 81310, Malaysia.

In this work, we report the preparation of polyacrylonitrile (PAN)-based activated carbon nanofibers composited with different concentrations of reduced graphene oxide (rGO/ACNF) (1%, 5%, and 10% relative to PAN weight) by a simple electrospinning method. The electrospun nanofibers (NFs) were carbonized and physically activated to obtain activated carbon nanofibers (ACNFs). Texture, surface and elemental properties of the pristine ACNFs and composites were characterized using various techniques. Read More

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September 2020

Osmolytes and membrane lipids in the adaptation of micromycete Emericellopsis alkalina to ambient pH and sodium chloride.

Fungal Biol 2020 10 29;124(10):884-891. Epub 2020 Jul 29.

Winogradsky Institute of Microbiology, Research Center of Biotechnology of the Russian Academy of Sciences, 33, Bld. 2, Leninsky Ave., Moscow, 119071, Russian Federation. Electronic address:

The accumulation of low molecular weight cytoprotective compounds (osmolytes) and changes in the membrane lipids composition are of key importance for the adaptation to stress impacts. However, the reason behind the wide variety of osmolytes present in the cell remains unclear. We suggest that specific functions of osmolytes can be revealed by studying the adaptation mechanisms of the mycelial fungus Emericellopsis alkalina (Hypocreales, Ascomycota) that is resistant to both alkaline pH values and high sodium chloride concentrations. Read More

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October 2020

Long-term responses of epiphytic midges (Diptera, Chironomidae) to emergent macrophytes removal and P concentrations in a shallow hypertrophic lake ecosystem.

Sci Total Environ 2021 Jan 4;750:141508. Epub 2020 Aug 4.

Department of Hydrobiology and Protection of Ecosystems, University of Life Sciences in Lublin, Dobrzańskiego 37, 20-262 Lublin, Poland.

Chironomid larvae are used as indicators of environmental changes in neolimnological and paleolimnological research. In the present study, we evaluated the responses of epiphytic chironomids to changes in environmental conditions over a long time scale. We intended to decipher whether changes in the trophic status of a lake (hypertrophic-eutrophic) would affect the taxonomic structure of epiphytic chironomids by influencing their food availability (structure of periphytic algae) and whether the responses of chironomids are taxa specific. Read More

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January 2021

Spatial lag effect of aridity and nitrogen deposition on Scots pine (Pinus sylvestris L.) damage.

Environ Pollut 2020 Oct 3;265(Pt B):114352. Epub 2020 Apr 3.

The Silva Tarouca Research Institute for Landscape and Ornamental Gardening, Lidická 25/27, CZ- 602 00, Brno, Czech Republic; Department of Environmental Studies, Faculty of Social Studies, Masaryk University, Joštova 10, CZ, Brno, Czech Republic.

Scots pine (Pinus sylvestris L.) is a widespread tolerant forest tree-species; however, its adaptability to environmental change differs among sites with various buffering capacity. In this study, we compared the spatial effects of aridity index (AI) and nitrogen deposition (ND) on biomass density in natural and man-made pine stands of differing soil fertility using geographically weighted multiple lag regression. Read More

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October 2020

Supramolecular hydrogels based on custom-made poly(ether urethane)s and cyclodextrins as potential drug delivery vehicles: design and characterization.

J Mater Chem B 2020 09 29;8(34):7696-7712. Epub 2020 Jul 29.

Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129, Torino, Italy.

The design of supramolecular (SM) hydrogels based on host-guest complexes represents an effective strategy to develop drug delivery systems. In this work, we designed SM hydrogels based on α-cyclodextrin and high-molar mass amphiphilic poly(ether urethane)s (PEUs, ) based on Poloxamer® 407 and differing in their chain extender. The successful formation of poly(pseudo)rotaxanes and their supramolecular interactions were chemically demonstrated. Read More

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September 2020

Avifauna habitability of wetlands in an intensive cultural landscape: insights from the Ichhamati floodplains, India.

Environ Monit Assess 2020 May 6;192(6):329. Epub 2020 May 6.

Department of Geography, Jadavpur University, Kolkata, 700032, India.

Wetlands of Ichhamati floodplains, India, are endowed repositories of native and migratory avifauna. However, unplanned utilization and unregulated resource extractions had led to the continual ecological deterioration of these wetland habitats. Considering avifauna habitability as an environmental manifestation of wetland health, the present study attempted to assess the habitability status of major 18 wetlands (> 10 ha) of the floodplains under different livelihood dependency patterns. Read More

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[Brief History of Insecticide-Treated Bed Nets in the Fight against Malaria: A Testimony on the Crucial 1980's Decade].

V Robert

Bull Soc Pathol Exot 2020 ;113(2):88-103

IRD-Délégation régionale Occitanie, 911 av. Agropolis, BP 64501, F-34394 Montpellier cedex 05, France.

In thirty years, bed nets treated with pyrethroids have been established as a means of prevention against malaria for personal protection and in public health. One of the actors of these discoveries gives an overview of insecticidetreated bed nets (ITNs) and brings his testimony, more particularly on the circumstances and frames of mind which prevailed in the 1980's, a crucial decade for these breakthroughs which served humanity. In 1983, the first experiment testing the effect of bed nets treated with pyrethroid insecticide was performed and revealed the impact of this method on the reduction of Plasmodium transmission. Read More

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January 2020

[Characteristics of Aerosol Particulate Concentrations and Their Climate Background in Shanghai During 2007-2016].

Huan Jing Ke Xue 2020 Jan;41(1):14-22

Key Laboratory of Cities Mitigation and Adaptation to Climate Change in Shanghai, Shanghai Climate Center, Shanghai 200030, China.

We use daily aerosol particulate matter<10 μm (PM) concentration data from 2006 to 2016 in Shanghai along with meteorological elements (wind and temperature), atmospheric stability, temperature inversion, and upper atmosphere circulation data, to analyze the variation characteristics of the PM concentrations and differences of the winter climate background. We establish a multivariate linear stepwise regression equation, and also compare and analyze differences in the upper atmospheric circulation by selecting the years with the highest and lowest PM concentrations. The results showed an oscillating downward trend in the annual average concentrations of PM in Shanghai, whereas seasonally, PM concentrations were relatively high in winter and showed two peaks with a low in between. Read More

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January 2020

Removal of bromate from drinking water using a heterogeneous photocatalytic mili-reactor: impact of the reactor material and water matrix.

Environ Sci Pollut Res Int 2019 Nov 13;26(32):33281-33293. Epub 2019 Sep 13.

Laboratory of Separation and Reaction Engineering-Laboratory of Catalysis and Materials (LSRE-LCM), Departamento de Engenharia Química, Faculdade de Engenharia, Universidade do Porto, Rua Dr. Roberto Frias, 4200-465, Porto, Portugal.

The main goal of this study was to evaluate the removal of bromate from drinking water using a heterogeneous photocatalytic mili-photoreactor, based on NETmix technology. The NETmix mili-reactor consists of a network of channels and chambers imprinted in a back slab made of acrylic (AS) or stainless steel (SSS) sealed, through mechanical compression and o-rings, with an UVA-transparent front borosilicate glass slab (BGS). A plate of UVA-LEDs was placed above the BGS window. Read More

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November 2019

Treatment of metal (loid) contaminated solutions using iron-peat as sorbent: is landfilling a suitable management option for the spent sorbent?

Environ Sci Pollut Res Int 2019 Jul 23;26(21):21425-21436. Epub 2019 May 23.

Department of Civil, Environmental and Natural Resources Engineering, Lulea University of Technology, SE-97187, Lulea, Sweden.

This study firstly aimed to investigate the potential of simultaneous metal (loid) removal from metal (oid) solution through adsorption on iron-peat, where the sorbent was made from peat and Fe by-products. Up-flow columns filled with the prepared sorbent were used to treat water contaminated with As, Cu, Cr, and Zn. Peat effectively adsorbed Cr, Cu, and Zn, whereas approximately 50% of inlet As was detected in the eluent. Read More

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[Mid-Term Results of Treatment of Severe Grades of Slipped Capital Femoral Epiphysis without Surgical Hip Dislocation].

Acta Chir Orthop Traumatol Cech 2019 ;86(1):23-32

Ortopedická klinika 1. lékařské fakulty Univerzity Karlovy, Institutu postgraduálního vzdělávání ve zdravotnictví a Nemocnice Na Bulovce, Praha.

PURPOSE OF THE STUDY To evaluate the results of treatment of acute and chronic severe slips of slipped capital femoral epiphysis. The tested hypothesis was that the results will be comparable with the methods using surgical hip dislocation. MATERIAL AND METHODS In the period 1996-2014, 26 patients were treated for severe slips ( >60°). Read More

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[Sex and line differences in biochemical indices and fat soluble vitamins sufficiency in rats on model of metabolic syndrome].

Vopr Pitan 2018 18;87(1):51-62. Epub 2017 Dec 18.

Federal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow.

Consumption of diets that are inadequate in energy value to the actual energy expenditure can lead to the development of metabolic syndrome (MS), which has consequences such as type 2 diabetes mellitus, non-alcoholic steatohepatosis, atherosclerosis, gout, allergic diseases. Experimental models of MS are needed to develop new approaches to its dietary and drug correction. The aim of the work was a comparative analysis of functional, biochemical and vitamin markers characterizing the effect of a diet with a high content of fructose (F) on males and females of various rat lines and the selection on this basis of an optimal in vivo MS model. Read More

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