105,579 results match your criteria preterm

Association of Surgical Necrotizing Enterocolitis and its Timing with Retinopathy of Prematurity.

Am J Perinatol 2021 Aug 3. Epub 2021 Aug 3.

Division of Neonatology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Objective:  The study aimed to determine the association of surgical necrotizing enterocolitis (NEC) and its timing, with the development and timing of retinopathy of prematurity (ROP).

Study Design:  This was a secondary data analysis of 7,483 preterm infants from the Postnatal Growth and Retinopathy of Prematurity Study. Associations between infants with surgical NEC, early-onset surgical NEC (8-28 days), and late-onset surgical NEC (over 28 days) with ROP were evaluated by using multivariable logistic regression models, controlling for birth weight, gestational age, small for gestational age status, chronic lung disease, intraventricular hemorrhage, hydrocephalus, patent ductus arteriosus, and periventricular leukomalacia. Read More

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Chloroorganic (DDT) and organophosphate (malathion) insecticides impair the motor function of the bovine cervix.

Toxicol Appl Pharmacol 2021 Jul 31:115667. Epub 2021 Jul 31.

Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Tuwima Street 10, 10-748 Olsztyn, Poland.

Dichlorodiphenyltrichloroethane (DDT) is a representative organochlorine insecticide and a known endocrine disruptor. Malathion is an organophosphate insecticide and a next-generation pesticide. Previously, it was shown that oxytocin (OT) and prostaglandins (PGs) are involved in the mechanism of the adverse effect of DDT on bovine myometrial contractions. Read More

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Factors That Influence Women's Symptoms of Postpartum Depression After Discharge of Their Preterm Infants From the NICU.

Christine Grippi

J Obstet Gynecol Neonatal Nurs 2021 Jul 31. Epub 2021 Jul 31.

Objective: To examine resourcefulness, perception of child vulnerability, and stress in relation to symptoms of postpartum depression (PPD) in women after discharge of their preterm infants from the NICU.

Design: Cross-sectional, descriptive, correlational study.

Setting: An urban NICU follow-up clinic, a pediatric office in the northeastern United States, and an online NICU parent support group. Read More

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C-Reactive Protein, Interleukin-6, and Procalcitonin in Diagnosis of Late-Onset Bloodstream Infection in Very Preterm Infants.

J Pediatric Infect Dis Soc 2021 Aug 3. Epub 2021 Aug 3.

Department of Neonatology, Institute for the Care of Mother and Child-Neonatology, Prague, Czech Republic.

Background: Late-onset bloodstream infection (LOBSI) is common in very preterm infants. Early and accurate diagnosis is crucial for prognosis and outcome. We aimed to analyze the accuracy of routinely used inflammatory biomarkers in the diagnosis of LOBSI as compared to uninfected controls. Read More

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Prenatal acetaminophen use in women with autoimmune disorders and adverse pregnancy and birth outcomes.

Rheumatology (Oxford) 2021 Aug 3. Epub 2021 Aug 3.

Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA.

Objectives: Most women may have temporary pain for which they use analgesics, but those with autoimmune disorders have chronic pain that may be exacerbated for some during pregnancy. This study aimed to determine whether prenatal acetaminophen use was associated with an increased risk of adverse pregnancy and birth outcomes in women with autoimmune disorders.

Methods: Participants were enrolled between 2004 and 2018 in the MotherToBaby cohort study and limited to women with an autoimmune disorder (n = 1,821). Read More

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Prevalence and risk factors for antimicrobial resistance among newborns with gram-negative sepsis.

PLoS One 2021 3;16(8):e0255410. Epub 2021 Aug 3.

St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.

Introduction: Newborn sepsis accounts for more than a third of neonatal deaths globally and one in five neonatal deaths in Ethiopia. The first-line treatment recommended by WHO is the combination of gentamicin with ampicillin or benzylpenicillin. Gram-negative bacteria (GNB) are increasingly resistant to previously effective antibiotics. Read More

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Fasting plasma glucose in the first trimester is related to gestational diabetes mellitus and adverse pregnancy outcomes.

Endocrine 2021 Aug 3. Epub 2021 Aug 3.

Department of Obstetrics, Shenzhen Maternity & Child Healthcare Hospital, The First School of Clinical Medicine, Southern Medical University, Hongli Road, Futian District, Shenzhen, Guangdong Province, China.

Purpose: To investigate and identify first-trimester fasting plasma glucose (FPG) is related to gestational diabetes mellitus (GDM) and other adverse pregnancy outcomes in Shenzhen population.

Methods: We used data of 48,444 pregnant women that had been retrospectively collected between 2017 and 2019. Logistic regression analysis was used to evaluated the associations between first-trimester FPG and GDM and adverse pregnancy outcomes, and used to construct a nomogram model for predicting the risk of GDM. Read More

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Structural and functional brain connectivity in moderate-late preterm infants with low-grade intraventricular hemorrhage.

Neuroradiology 2021 Aug 3. Epub 2021 Aug 3.

Department of Medical Physics, Faculty of Medicine, University of Ioannina, Ioannina, Greece.

Purpose: Brain functional connectivity (FC) changes and microstructural abnormalities are reported in infants born moderate and late preterm (MLPT). We evaluated the effect of low-grade (grades I, II) intraventricular hemorrhage (IVH) in MLPT babies on brain structural connectivity (SC) and FC.

Methods: Babies born MLPT between January 2014 and May 2017 underwent brain ultrasound (US) at 72 h and 7 days after birth, and MRI at around term equivalent. Read More

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Factors related to age at natural menopause in China: results from the China Kadoorie Biobank.

Menopause 2021 Aug 2. Epub 2021 Aug 2.

Department of Non-Communicable Disease Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK Chinese Academy of Medical Sciences, Dong Cheng District, Beijing, China Department of Epidemiology, School of Public Health, Peking University Health Science Center, Haidian District, Beijing, China School of Biotechnology and Health Sciences, Wuyi University, Jiangmen, China.

Objectives: The aim of this study was to investigate the potentially modifiable factors affecting age at natural menopause (ANM) in Chinese women.

Methods: We used cross-sectional data from the China Kadoorie Biobank study which that recruited 0.5 million (0. Read More

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Maternal chronic hepatitis B virus infection and the risk of preterm birth: a retrospective cohort analysis in Chinese Women.

J Viral Hepat 2021 Aug 3. Epub 2021 Aug 3.

Department of Obstetrics, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai Key Laboratory of maternal fetal medicine.NO, 2699 West Gaoke Road, Shanghai, 201204, China.

The association between different clinical states of chronic HBV infection and preterm birth (PTB) is still controversial. A retrospective cohort study among 57,386 pregnant women was conducted to examine the impact of chronic HBsAg positive, both HBsAg and HBeAg positive, and chronic active hepatitis on pregnancy complications related to the overall PTB and its subtypes (spontaneous and iatrogenic). A total of 54,245 pregnancies were included in the final study cohort, among which 2,151(4. Read More

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Gestational age and birth growth parameters as early predictors of fetal alcohol spectrum disorders.

Alcohol Clin Exp Res 2021 Aug 2. Epub 2021 Aug 2.

Gillings School of Global Public Health, Nutrition Research Institute, University of North Carolina, Chapel Hill, NC, USA.

Objective: To investigate gestational age and growth at birth as predictors of fetal alcohol spectrum disorders (FASD).

Methods: The sample analyzed here comprises 737 randomly selected children who were assessed for growth, dysmorphology, and neurobehavior at 7 years of age. Maternal interviews were conducted to ascertain prenatal alcohol exposure and other maternal risk factors. Read More

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Mueller matrix imaging for collagen scoring in mice model of pregnancy.

Sci Rep 2021 Aug 2;11(1):15621. Epub 2021 Aug 2.

LPICM, CNRS, Ecole polytechnique, IP Paris, 91128, Palaiseau, France.

Preterm birth risk is associated with early softening of the uterine cervix in pregnancy due to the accelerated remodeling of collagen extracellular matrix. Studies of mice model of pregnancy were performed with an imaging Mueller polarimeter at different time points of pregnancy to find polarimetric parameters for collagen scoring. Mueller matrix images of the unstained sections of mice uterine cervices were taken at day 6 and day 18 of 19-days gestation period and at different spatial locations through the cervices. Read More

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Association of preterm low-birth-weight infants and maternal periodontitis during pregnancy: An interventional study.

J Indian Soc Pedod Prev Dent 2021 Apr-Jun;39(2):183-188

Department of Pediatric and Preventive Dentistry, K.M.Shah Dental College and Hospital, Sumandeep Vidyapeeth, Gujarat, India.

Context: The impact of periodontal disease during pregnancy and its effect on adverse pregnancy outcomes is seen in the literature. When it comes to the link of disease related to periodontium to that of adverse pregnancy outcomes, a need can arise if a significant cause-effect relationship does exist or not between them.

Aim: The study was aimed to determine the association of periodontal health status in pregnant women with the occurrence of preterm low birth weight (LBW) infants in Vadodara, Gujarat. Read More

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Nephrotoxicity in Neonates.

Neoreviews 2021 Aug;22(8):e506-e520

Department of Gynecology-Obstetrics and Pediatrics, Faculty of Medicine of Porto University, Porto, Portugal.

Acute kidney injury (AKI) is classified based on prerenal, intrinsic, and postrenal causes. In the newborn, AKI can occur after an insult during the prenatal, perinatal, or postnatal period. AKI is usually an underrecognized condition and its true incidence is unknown. Read More

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Parental Stress and Mental Health Symptoms in the NICU: Recognition and Interventions.

Neoreviews 2021 Aug;22(8):e496-e505

Division of Child Psychiatry, Stanford University School of Medicine, Palo Alto, CA.

Parental experiences in the NICU are often characterized by psychological stress and anxiety following the birth of a critically ill or premature infant. Such stress can have a negative impact on parents and their vulnerable infants during NICU hospitalization as well as after discharge. These infants are also at increased risk for adverse developmental, cognitive, academic, and mental health outcomes. Read More

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Parental Depression After Preterm Birth: An Opportunity for Prevention.

Michael W Yogman

Pediatrics 2021 Aug 18;148(2). Epub 2021 Jun 18.

Department of Pediatrics, Cambridge Hospital, Harvard Medical School, Harvard University, Cambridge, Massachusetts

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Advancing the Evidence Base in the Care of Term and Late Preterm Infants.

Hosp Pediatr 2021 Aug 2. Epub 2021 Aug 2.

Stead Family Department of Pediatrics, University of Iowa Stead Family Children's Hospital, Iowa City, Iowa.

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Improving the admission temperatures of preterm infants in the neonatal unit.

Arch Dis Child Educ Pract Ed 2021 Aug 2. Epub 2021 Aug 2.

Women's and Babies' Division, Women's and Children's Health Network, North Adelaide, South Australia, Australia.

Use of plan-do-study-act cycles to increase the proportion of preterm infants born at <32 weeks' gestation admitted to a neonatal unit with a body temperature of 36.5-37.4°C. Read More

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Hypothyroxinaemia in refractory shock: a clue to diagnose hypopituitarism.

BMJ Case Rep 2021 Aug 2;14(8). Epub 2021 Aug 2.

Department of Neonatology, Sri Ramachandra Institute of Higher Education and Research, Chennai, India

The rarity of congenital hypopituitarism (CHP) makes it essential for clinicians to be aware of its varying clinical manifestations. We report a neonate with one such unique presentation. A preterm girl baby was managed for respiratory distress. Read More

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[Neuromonitoring of the extremely preterm infant].

An Pediatr (Barc) 2021 Jul 30. Epub 2021 Jul 30.

Neurología Neonatal, Fundación NeNe, España.

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Investigation of a cluster of Bacillus cereus bacteremia in neonatal care units.

J Microbiol Immunol Infect 2021 Jul 19. Epub 2021 Jul 19.

Department of Pediatrics, Chang Gung Memorial Hospital at Linkou, Kweishan, Taoyuan, Taiwan; School of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan. Electronic address:

Background: Bacillus cereus is a well-known pathogen for self-limited foodborne illness, and rarely an opportunistic pathogen associated with invasive infections among immunocompromised patients. Nosocomial outbreaks have been rarely reported.

Methods: Between August and November 2019, four preterm neonates in neonatal care units of a medical center developed late-onset B. Read More

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The impact of indomethacin on the number of oocytes retrieved and IVF outcomes in patients with poor ovarian response.

Eur J Obstet Gynecol Reprod Biol 2021 Jul 24;264:266-270. Epub 2021 Jul 24.

Center for Assisted Reproduction, Department of Obstetrics and Gynecology, Ankara University Faculty of Medicine, Ankara, Turkey.

Objective: The aim of this retrospective case-control study was to analyze the effect of administering indomethacin after triggering final oocyte maturation in patients with poor ovarian response (POR) on the cycle cancellation rate due to premature ovulation (PO), the number of oocytes retrieved and the clinical outcomes of IVF cycles.

Study Design: A total of 214 patients with POR, diagnosed according to the Bologna criteria, who underwent fresh IVF cycle via flexible gonadotrophin-releasing hormone antagonist (GnRH-ant) protocol were enrolled in the study. The control group consisted of 100 patients, whereas the indomethacin group included 114 patients who received 100 mg rectal indomethacin administered twice within the same day (twelve hours apart) -starting at twelve hours after triggering. Read More

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Performance in Hand Coordination Tasks and Concurrent Functional MRI Findings in 13-Year-Olds Born Very Preterm.

Pediatr Neurol 2021 Jul 10;123:21-29. Epub 2021 Jul 10.

Department of Pediatric Neurology, University of Turku, Turku, Finland; Turku University Hospital, Turku, Finland.

Background: Fine motor and coordination problems are frequently reported among adolescents born preterm. We aimed to assess performance in hand coordination tasks and to compare concurrent brain activation between adolescents born very preterm and at term at 13 years.

Methods: A total of 34 right-handed adolescents born very preterm (gestational age less than 32 weeks/birth weight ≤1500 grams) and 37 controls born at term during 2003 to 2006 in Turku University Hospital, Finland, were recruited. Read More

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Urinary glyphosate concentration in pregnant women in relation to length of gestation.

Environ Res 2021 Jul 30:111811. Epub 2021 Jul 30.

Department of Environmental Medicine and Public Heath, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address:

Human exposure to glyphosate-based herbicides (GBH) is increasing rapidly worldwide. Most existing studies on health effects of glyphosate have focused on occupational settings and cancer outcomes and few have examined this common exposure in relation to the health of pregnant women and newborns in the general population. We investigated associations between prenatal glyphosate exposure and length of gestation in The Infant Development and the Environment Study (TIDES), a multi-center US pregnancy cohort. Read More

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Evaluation of nutrition status of very preterm infants in neonatal intensive care units using different growth indicators.

Nutr Clin Pract 2021 Aug 2. Epub 2021 Aug 2.

Nanjing Maternity and Child Health Care Hospital, Women's Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.

Background:  Nutrition status of very preterm infants in the neonatal intensive care unit (NICU) is strongly associated with postnatal growth. This study aimed to develop indicators of nutrition status using growth data of very preterm infants during hospitalization.

Methods: The data of 596 newborns from eight NICUs were retrospectively analyzed. Read More

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Distended abdomen due to a pseudocyst around a ventriculoperitoneal shunt.

Wien Med Wochenschr 2021 Aug 2. Epub 2021 Aug 2.

Department of Pediatric Cardiology, University Medical Center of Saarland, Homburg, Germany.

Described herein is a case of distended abdomen in a 4-year-old boy with a ventriculoperitoneal (VP) shunt due to bilateral intraventricular hemorrhage following premature birth. Physical examination and laboratory tests revealed tenderness in the lower quadrants, with mild leukocytosis and normal C‑reactive protein levels. X‑ray demonstrated an intact VP shunt catheter but cranial displacement of the large intestine. Read More

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Soft tissue infection as a rare cause of neonatal sepsis.

Wien Med Wochenschr 2021 Aug 2. Epub 2021 Aug 2.

Department of Pediatrics and Neonatology, Saarland University Medical Center, Homburg/Saar, Germany.

Umbilical venous and peripherally inserted central venous catheters are often used in preterm infants, but complications include late-onset catheter-associated infections. Conversely, other sites of infection have to be taken into account in the case of clinical deterioration. In this Image in Science and Medicine paper, we report on a preterm infant with a rare cause of neonatal sepsis. Read More

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Neonatal Intensive Care for Very Preterm Infants in China.

JAMA Netw Open 2021 Aug 2;4(8):e2118940. Epub 2021 Aug 2.

Division of Neonatology, Stead Family Department of Pediatrics, University of Iowa, Iowa City.

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Assessment of Neonatal Intensive Care Unit Practices, Morbidity, and Mortality Among Very Preterm Infants in China.

JAMA Netw Open 2021 Aug 2;4(8):e2118904. Epub 2021 Aug 2.

Division of Neonatology, Children's Hospital of Fudan University, Shanghai, China.

Importance: The Chinese Neonatal Network was established in 2018 and maintains a standardized national clinical database of very preterm or very low-birth-weight infants in tertiary neonatal intensive care units (NICUs) throughout China. National-level data on outcomes and care practices of very preterm infants (VPIs) in China are lacking.

Objective: To assess the care practices in NICUs and outcomes among VPIs in China. Read More

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Association of Expanded Prenatal Care Coverage for Immigrant Women With Postpartum Contraception and Short Interpregnancy Interval Births.

JAMA Netw Open 2021 Aug 2;4(8):e2118912. Epub 2021 Aug 2.

Center for Health Systems Effectiveness, Oregon Health & Science University, Portland.

Importance: Access to prenatal and postpartum care is restricted among women with low income who are recent or undocumented immigrants enrolled in Emergency Medicaid.

Objective: To examine the association of extending prenatal care coverage to Emergency Medicaid enrollees with postpartum contraception and short interpregnancy interval births.

Design, Setting, And Participants: This cohort study used a difference-in-differences design to compare the staggered rollout of prenatal care in Oregon with South Carolina, a state that does not cover prenatal or postpartum care. Read More

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