Ann Biomed Eng 2021 Feb 26. Epub 2021 Feb 26.
Department of Biomedical Engineering, The Pennsylvania State University, Chemical and Biomedical Engineering Building, 122, University Park, PA, 16802, USA.
Transcatheter aortic valve replacements (TAVRs) provide minimally invasive delivery of bioprosthetic heart valves (BHVs) for the treatment of aortic valve disease. While surgical BHVs show efficacy for 8-10 years, long-term TAVR durability remains unknown. Pre-clinical testing evaluates BHV durability in an ISO:5840 compliant accelerated wear tester (AWT), yet, the design and development of AWTs and their accuracy in predicting in vivo performance, is unclear. Read More