124,489 results match your criteria presenting case

Differential diagnosis of acute traumatic hip pain in the elderly.

Acta Orthop Belg 2021 Mar;87(1):1-7

Elderly patients who present with an inability to weight bear following a fall, with normal radiographs, should be appropriately investigated to rule out an occult hip fracture (OHF). We aim to identify both the range and incidence of the differential diagnosis of acute traumatic hip pain in a large series of patients investigated for OHF. A retrospective analysis of consecutive patients investigated for an OHF with magnetic resonance imaging (MRI) was performed. Read More

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Management of traumatic posterior fossa epidural hematomas in pediatrics: our experience and review of the literature.

Childs Nerv Syst 2021 Jun 15. Epub 2021 Jun 15.

Faculty of Medicine, Jordan University of Science and Technology, Irbid, 22110, Jordan.

Background And Aims: Conservative management of posterior fossa epidural hematoma in the pediatric age group has been increasingly considered in the last decade with good clinical outcomes and comparable results to surgical intervention in carefully selected patients. The purpose of this study is to evaluate the outcome of observation in the management of pediatric patients with posterior fossa epidural hematoma (PFEDH) in our tertiary hospital and present a literature review on PFEDH pediatric patients.

Methods: We conducted a retrospective observational study at King Abdullah University Hospital (KAUH), a tertiary hospital in North Jordan. Read More

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Sphenoid sinus pseudoaneurysm with carotid cavernous fistula presenting with delayed subarachnoid hemorrhage: A case report.

Medicine (Baltimore) 2021 Jun;100(24):e26383

Department of Radiology.

Rationale: Sphenoid sinus pseudoaneurysm arising from the cavernous segment of the internal carotid artery (ICA) caused by traumatic vessel injury is rare, and rarer is a concomitant carotid-cavernous fistula (CCF). In particular, delayed subarachnoid hemorrhage (SAH) due to pseudoaneurysm rupture has not been reported to-date in literature. Here, we report a case of sphenoid sinus pseudoaneurysm with CCF presenting with delayed SAH. Read More

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Antiviral and Immunological Activity of Zinc and Possible Role in COVID-19.

Br J Nutr 2021 Jun 15:1-21. Epub 2021 Jun 15.

Universidade Federal do Piauí, Teresina, PI, Brazil.

Zinc deficiency compromises its biological functions, its effect on the immune system and its antiviral activity, increasing vulnerability to infectious diseases. This narrative review aims at presenting and discussing functional aspects and possible mechanisms involved in the potential role of zinc in the immune response and antiviral activity for COVID-19 prevention and control. The searches were conducted in PubMed and Science Direct databases, using clinical trials, experimental studies in animals and humans, case-control studies, case series, letters to the editor, and review articles published in English, without restrictions on year of publication. Read More

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A Case of Rapid Transformation from Hydatidiform Mole to Invasive Mole: The Importance of β-hCG (Human Chorionic Gonadotropin) Serum Levels in Follow-Up Evaluation.

Am J Case Rep 2021 Jun 15;22:e931156. Epub 2021 Jun 15.

Division of Pharmacology and Therapy, Department of Anatomy, Histology, and Pharmacology, Faculty of Medicine Universitas Airlangga, Surabaya, Indonesia.

BACKGROUND Gestational trophoblastic disease (GTD) is a spectrum of disorders consisting of premalignant (ie, complete [CHM] and partial hydatidiform moles [PHM]) and malignant conditions (ie, invasive moles, choriocarcinoma, placental site trophoblastic tumors, and epithelioid trophoblastic tumor). If GTD persists after initial treatment and has persistent elevated beta human chorionic gonadotropin (ß-hCG), it is referred to as post-molar gestational trophoblastic neoplasia (pGTN). To date, there is no detailed information regarding how fast invasive moles can develop from CHM. Read More

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Iris metastasis from breast cancer successfully treated with Abemaciclib and Letrozole.

Retin Cases Brief Rep 2021 Jun 11. Epub 2021 Jun 11.

Bascom Palmer Eye Institute, University of Miami Miller School of Medicine Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine Moffitt Cancer Center, University of South Florida, Morsani College of Medicine.

Purpose: To describe a patient with an unusual presentation of iris metastasis from breast cancer and her response to systemic therapy.

Methods: Retrospective chart review of one patient.

Results: A 57-year-old woman presented with a superonasal translucent vascularized iris stromal mass with fish egg-like structures budding from the surface. Read More

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Cerebrospinal fluid HIV RNA escape symptomatology.

AIDS 2021 Jun 15. Epub 2021 Jun 15.

Mildmay Hospital, London, UK Unit of Infectious Diseases, San Raffaele Hospital, Milan, Italy Section of Retrovirology, Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK Department of HIV Medicine, St. Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK Unit of Neuroradiology, ASST Papa Giovanni XXIII, Bergamo, Italy Lazzaro Spallanzani National Institute of Infectious Diseases, Rome, Italy San Paolo Hospital, University of Milan, Milan, Italy University of Bari, Bari, Italy Unit of Infectious Diseases, Department of Medical Sciences, University of Turin, Turin, Italy Department of Neurology, St. Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK Neurosciences, Blizard Institute, Queen Mary University of London, London, UK Grahame Hayton Unit, I&I and Neurology Department, Barts Health NHS Trust, London, UK.

Objective: To characterise the clinical, laboratory and radiological characteristics of persons with HIV (PWH) presenting with cerebrospinal fluid (CSF) HIV RNA escape.

Design: Retrospective case review of PWH presenting with symptomatic CSF HIV RNA escape at seven tertiary HIV clinical sites in UK and Italy.

Method: PWH with symptomatic CSF HIV RNA escape episodes were identified and data obtained from medical records. Read More

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Can PIMS-TS lead to a facial nerve palsy?

BMJ Case Rep 2021 Jun 14;14(6). Epub 2021 Jun 14.

Department of Infectious Diseases and Tropical Medicine, Guys and St Thomas Hospital, London, UK.

Paediatric inflammatory multisystem syndrome-temporally associated with SARS-CoV-2 (PIMS-TS) is a recently described syndrome. We describe the case of a 17-year-old man presenting with a recent illness consistent with COVID-19 who presented with fever, chest pain and anterior uveitis. He was treated with aspirin, pulsed methylprednisolone and tocilizumab followed by oral steroids. Read More

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Methylphenidate-Induced Chorea Due to Possible Cytochrome P450 Metabolism Heterogeneity - A Rare Case.

CNS Spectr 2021 Apr;26(2):176-177

University of Colorado, Department of Neurosurgery, Aurora, CO, USA.

Background: Chorea is defined as a hyperactive movement disorder associated with involuntary, quick, and unpredictable muscle contractions of the limbs, face, and trunk. The unpredictable nature of these movements includes variation in speed, timing, and direction of movement. A wide variety of medications, medical conditions and illicit drugs have been associated with movement disorders. Read More

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A Multiparametric MRI Protocol for Evaluation of Cognitive Insufficiency, Dementia and Traumatic Brain Injury (TBI): A Case Series.

CNS Spectr 2021 Apr;26(2):179

Colorado Springs Neurological Associates, Colorado Springs, CO, USA.

Background: The purpose of this work was to determine the extent to which a multiparametric magnetic resonance imaging (MRI) approach to patients with dementia and/or traumatic brain injury (TBI) can help to determine the most likely diagnosis and the prognosis of these patients.

Objective: Volumetric brain MRI alone is recognized as a useful imaging tool to differentiate behavioral variant frontotemporal dementia (bvFTD) from the more common Alzheimer's disease (AD). Our objective is to create a protocol that will provide additional non-standard, objective imaging data that can be utilized clinically to distinguish common and uncommon forms of dementia and TBI. Read More

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Evaluation of patients admitted with musculoskeletal tuberculosis: sixteen years' experience from a single center in Turkey.

BMC Musculoskelet Disord 2021 Jun 14;22(1):542. Epub 2021 Jun 14.

Osmaniye State Hospital Pathology Department, Akyar Central Location Hospital Street Center, 80010, Osmaniye, Turkey.

Background: The aim of our study was to describe musculoskeletal system tuberculosis (TB) as a single-center experience.

Methods: This is a retrospective observational study conducted at a TB Dispensary in the east Mediterranean part of Turkey between 2004 and 2020. The clinical and demographic characteristics including age, gender, involvement location and duration of illness, presenting complaint, local examination findings, treatment outcome were retrieved and analyzed from the case files. Read More

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Clinical utility of the ECLECTIC framework in providing culturally-informed autism spectrum disorder evaluations: a pediatric case-based approach.

Clin Neuropsychol 2021 Jun 14:1-24. Epub 2021 Jun 14.

Department of Pediatrics, Division of Developmental-Behavioral Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Social cognition does not exist within a vacuum. One's culture and surrounding social environment influence 1) development of social skills and behaviors, and 2) society's expectations regarding "normal" behavior versus behaviors consistent with the diagnosis of Autism Spectrum Disorder (ASD). Use of a comprehensive cultural framework such as Fujii's ECLECTIC model undergirds valid ASD testing by enhancing clinician awareness of potential biases during clinical decision-making and by supporting culturally relevant recommendations. Read More

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The Sensorineural Hearing Loss Related to a Rare Infratentorial Developmental Venous Angioma: A Case Report and Review of Literature.

J Neurol Surg A Cent Eur Neurosurg 2021 Jun 14. Epub 2021 Jun 14.

Department of Neurosurgery, Skull Base Research Center, Shahid Beheshti University of Medical Sciences, Loghman Hakim Hospital, Tehran, Iran.

Background:  Developmental venous anomaly (DVA) is a benign venous abnormality draining normal brain parenchyma. It is mostly asymptomatic; however, rare complications such as hemorrhage may lead to symptomatic conditions. Headache and seizure are the most common symptoms. Read More

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Subcutaneous emphysema and spontaneous pneumomediastinum in non-intubated COVID-19 patient: Presenting unusual case report.

Int J Surg Case Rep 2021 Jun 10;84:106071. Epub 2021 Jun 10.

Department of Critical Care Nursing, College of Nursing, Urmia University of Medical Science, Iran. Electronic address:

Introduction And Importance: In non-intubated COVID-19 patients, subcutaneous emphysema and spontaneous pneumomediastinum (SPM) remain rarely, with incidence rates of 3.0 and 1.2 per 100,000, respectively; nevertheless, the occurrence of these conditions in COVID-19 patients is unclear. Read More

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IGF1 Haploinsufficiency in Children with Short Stature: A Case Series.

Eur J Endocrinol 2021 Jun 1. Epub 2021 Jun 1.

D Beckers, Pediatric Endocrinology, Université Catholique de Louvain, CHU UCL Namur, Yvoir, Belgium.

Context: Short stature in children is a common reason for referral to pediatric endocrinologists. The underlying cause of short stature remains unclear in many cases and patients often receive unsatisfactory, descriptive diagnoses. While textbooks underline the rarity of genetic causes of growth hormone (GH) insensitivity and the severity of its associated growth failure, increased genetic testing in patients with short stature of unclear origin has revealed gene defects in the GH/ insulin-like growth factor (IGF-I) axis associated with milder phenotypes. Read More

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Effects of Vitamin D Supplefmentation on Outcome of Low-Calorie Diet in Workers Presenting Obesity or Overweight: A Retrospective Observational Study.

J Am Coll Nutr 2021 Jun 14:1-9. Epub 2021 Jun 14.

Department of Preventive Medicine, Occupational Health Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.

Aim: Growing evidence underscores the inverse association between serum vitamin D (vit D) and chronic conditions such as metabolic syndrome, diabetes and obesity. The aim of this retrospective study was to compare weight loss and metabolic serum biomarkers in subjects on low-calorie diet receiving vit D supplementation versus those not receiving it.

Methods: The study considered 405 indoor sedentary workers with overweight/obesity and vit D insufficiency, who participated to a health fitness program between 2011-2013. Read More

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Immediate Endoscopic Dacryocystorhinostomy in Patients With New Onset Acute Dacryocystitis.

Laryngoscope 2021 Jun 14. Epub 2021 Jun 14.

Department of Orbital and Oculoplastic Surgery, Eye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

Objectives: To compare the results of immediate endoscopic dacryocystorhinostomy (En-DCR) and delayed En-DCR in the treatment of new-onset acute dacryocystitis (AD).

Study Design: This report describes a prospective randomized controlled interventional case series.

Methods: Between April 2009 and May 2019, 176 adults presenting at a tertiary eye care center with new-onset AD manifesting within the last 48 hours were randomized into two groups. Read More

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Sport Concussion Assessment Tool-5th Edition (SCAT5): Normative Reference Values for the National Rugby League Women's Premiership.

Front Sports Act Living 2021 26;3:653743. Epub 2021 May 26.

Hunter New England Local Health District Sports Concussion Program, Newcastle, NSW, Australia.

To establish normative reference values for the Sport Concussion Assessment Tool-5th Edition (SCAT5) for the new National Rugby League Women's Premiership. Preseason SCAT5 baseline testing was administered individually to all National Rugby League Women's Premiership players ( = 117). Testing was completed by the medical staff. Read More

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Successful implantation of a leadless pacemaker in a patient with complete atrioventricular block and congenital absence of superior vena cava: a case report.

Eur Heart J Case Rep 2021 May 12;5(5):ytab167. Epub 2021 May 12.

Department Cardiovascular Medicine, Juntendo University Shizuoka Hospital, 1129 Nagaoka, Izunokuni-shi, Shizuoka-ken 410-2295, Japan.

Background: Congenital absence of superior vena cava (CASVC) is an extremely rare vascular anomaly often associated with conduction disturbances which makes implantation of a pacemaker difficult. We report a case of pacemaker implantation in a patient presenting with complete atrioventricular block (c-AVB) with bilateral absence of the SVC.

Case Summary: A 68-year-old man who had experienced dyspnoea on exertion by c-AVB was admitted to our hospital for treatment and management. Read More

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Interventricular septum mass presenting as a late acute coronary syndrome with ST-segment elevation: a case report.

Eur Heart J Case Rep 2021 May 12;5(5):ytab164. Epub 2021 May 12.

Radiology Department, Hopital Saint-Joseph, 185 Rue Raymond Losserand, 75014 Paris, France.

Background: Intracardiac masses are relatively rare but the diagnosis can be challenging for the cardiologist and the clinical presentation can be misleading. While most of the cardiac masses are benign, malignant masses are mostly metastatic tumours.

Case Summary: An 81-year-old man was admitted to the cardiology department for congestive heart failure with the complaint of recent dyspnoea. Read More

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Percutaneous management strategies for STEMI with coexisting aneurysmal coronary- to-pulmonary artery fistula: a case report.

Eur Heart J Case Rep 2021 May 16;5(5):ytab157. Epub 2021 May 16.

Section of Cardiovascular Medicine, Dartmouth-Hitchcock Medical Center, 1 Medical Center Drive, Lebanon, NH 03766, USA.

Background: Coexistence of coronary artery fistulas and atherosclerotic coronary artery disease (CAD) is rare.

Case Summary: We present a unique case of a patient initially presenting with an anterior ST-elevation myocardial infarction, subsequently found to have two-vessel CAD and an aneurysmal left coronary-to-right pulmonary artery fistula.

Discussion: After discussion with the patient and a multidisciplinary discussion with the heart team, consisting of cardiovascular surgery, interventional cardiology, and vascular surgery, a percutaneous approach was chosen. Read More

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A 'shark'-masked electrocardiogram: case report of a Tako-Tsubo syndrome.

Eur Heart J Case Rep 2021 May 7;5(5):ytab132. Epub 2021 May 7.

Division of Cardiology, Ospedale degli Infermi, ASL Biella, Via dei Ponderanesi, 13900 Biella, Italy.

Background: Triangular ST-segment elevation or 'shark-fin' sign has been described as a specific indicator of acute coronary occlusion and large myocardial ischaemia, translating into poorer prognosis. However, this electrocardiographic presentation has been reported in rare cases of Tako-Tsubo syndrome and associated with more severe physical stressors and neurological involvement.

Case Summary: We present a rare case of a 51-year-old woman presenting with incoming epileptic attacks and concomitant pyometra. Read More

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Carcinoid heart disease of gonadal primary presenting with hypoxia: a case report.

Eur Heart J Case Rep 2021 May 14;5(5):ytaa536. Epub 2021 May 14.

Department of Cardiology, St George Hospital, Gray Street, Kogarah 2217, NSW, Australia.

Background: Carcinoid heart disease is a potential sequela of metastatic neuroendocrine tumour that has characteristic valve appearances. Patients can present with symptoms of carcinoid syndrome or be relatively asymptomatic until symptoms of progressive heart failure manifest.

Case Summary: We present a case of a 54-year-old male who was admitted to the hospital for investigation of hypoxia. Read More

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Bullet-associated ventricular tachycardia: a case report.

Eur Heart J Case Rep 2021 Apr 26;5(4):ytab101. Epub 2021 Apr 26.

Department of Cardiology II (Electrophysiology), University Hospital Münster, Albert-Schweitzer-Campus 1, 48149 Münster, Germany.

Background: The majority of ventricular tachycardias (VTs) occurs in patients with structural heart disease and is associated with an increased risk of sudden cardiac death. These VT are scar-related and may develop in patients with ischaemic or non-ischaemic cardiomyopathies.

Case Summary: We describe a 44-year-old patient without any pre-existing cardiovascular disease, presenting with the first documentation of a haemodynamically unstable sustained fast VT with a cycle length of 250 ms. Read More

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Primary Care Case Management of Febrile Children: Insights From the ePOCT Routine Care Cohort in Dar es Salaam, Tanzania.

Front Pediatr 2021 28;9:626386. Epub 2021 May 28.

Swiss Tropical and Public Health Institute, Basel, Switzerland.

To provide insight in the primary health care (PHC) case management of febrile children under-five in Dar es Salaam, and to identify areas for improving quality of care. We used data from the routine care arm of the ePOCT trial, including children aged 2-59 months who presented with an acute febrile illness to two health centers in Dar es Salaam (2014-2016). The presenting complaint, anthropometrics, vital signs, test results, final diagnosis, and treatment were prospectively collected in all children. Read More

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Diagnostic Bias in the COVID-19 Pandemic: A Series of Short Cases.

Eur J Case Rep Intern Med 2021 11;8(5):002575. Epub 2021 May 11.

Milton Keynes University Hospital, Milton Keynes, UK.

During the COVID-19 pandemic, healthcare systems have faced unprecedented pressures. One challenge has been to promptly recognise non-COVID-19 conditions. Cognitive bias due to the availability heuristic may cause difficulties in reaching the correct diagnosis. Read More

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Monocular Diplopia in Idiopathic Intracranial Hypertension: A Case Report and Literature Review.

Eur J Case Rep Intern Med 2021 4;8(5):002509. Epub 2021 May 4.

Department of Neuroscience, Reproductive Science and Odontostomatology, Federico II University, Naples, Italy.

Background: Diplopia is the double vision of a single object, and can be binocular or monocular. Binocular diplopia is caused by the misalignment of the visual axes, with images falling on the fovea of the fixating eye and on the extra-foveal retina of the non-fixating eye, as a consequence of both neurological (i.e. Read More

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SARS CoV-2 infection in a patient with sickle cell disease - Atypical presentation.

J Family Med Prim Care 2021 Apr 29;10(4):1792-1794. Epub 2021 Apr 29.

Jazan Health, Kingdom of Saudi Arabia.

Severe acute respiratory syndrome coronavirus-2 (SARS CoV-2) infection causes the disease known as coronavirus disease that started in Wuhan (China) in December 2019, leading to the current COVID-19 pandemic. The common presenting symptoms include fever, dry cough, shortness-of-breath, while sore throat, diarrhea, and abdominal and chest pain are the least. The atypical presentation of SARS CoV-2 infection poses a challenge for family physicians to screen and manage such patients for COVID-19 and specifically those at high risk with underlying disease such a sickle cell disease. Read More

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COVID-19 presenting as acute transient flaccid limb paralysis.

J Family Med Prim Care 2021 Apr 29;10(4):1789-1791. Epub 2021 Apr 29.

Department of Pulmonary Medicine, Rajagiri Hospital, Chunangamvely, Aluva, Kochi, Kerala, India.

Novel corona virus pandemic in 2020 has created havoc across the world. Since its entry into Indian subcontinent in February 2020, it has become the second most affected country in the world. In this context we wish to share the case of a young man who presented with periodic paralysis was eventually diagnosed to have COVID-19 infection. Read More

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