30,527 results match your criteria presented produced


Modeling of short-pulse laser-metal interactions in the warm dense matter regime using the two-temperature model.

Phys Rev E 2021 Mar;103(3-1):033204

Naval Research Laboratory, Plasma Physics Division, 4555 Overlook Avenue SW, Washington, DC 20375, USA.

A numerical model for laser-matter interactions in the warm dense matter regime is presented with broad applications, e.g., ablation, thermionic emission, and radiation. Read More

View Article and Full-Text PDF

Enhanced nail delivery of voriconazole-loaded nanomicelles by thioglycolic acid pretreatment: a study of protein dynamics and disulfide bond rupture.

Int J Pharm 2021 Apr 13:120597. Epub 2021 Apr 13.

Laboratory of Nanosystems and Drug Delivery Devices (NanoSYS), School of Pharmacy - Universidade Federal de Goiás (UFG). Rua 240, esq. com 5ª Avenida, Setor Leste Universitário. 74605-170, Goiânia - GO Brazil. Electronic address:

This work aimed to select an effective penetration enhancer (PE) for nail pretreatment, develop voriconazole (VOR)-loaded nanomicelles, and evaluate their ability to deliver VOR to the nail. A complete analysis of nail protein dynamics, bond rupture, and microstructure was performed. Alternative methods as electron paramagnetic resonance (EPR) and the Ellman's reagent (DTNB) assay were also evaluated. Read More

View Article and Full-Text PDF

β-elemene affects angiogenesis of infantile hemangioma by regulating angiotensin-converting enzyme 2 and hypoxia-inducible factor-1 alpha.

J Nat Med 2021 Apr 16. Epub 2021 Apr 16.

Department of Pediatric Surgery, Affiliated Hospital of Nantong University, Nantong University, 19 Qixiu Road, Nantong, 226001, Jiangsu, China.

Infantile hemangioma (IH) is the most common benign vascular tumor resulting from the hyper-proliferation of vascular endothelial cells. In treatment of various tumors including IH, β-elemene, a compound extracted from Rhizoma zedoariae, has been reported to have anti-tumor effect. However, the underlying mechanisms of β-elemene in hemangioma have remained uninvestigated. Read More

View Article and Full-Text PDF

Wastewater treatment by microalgae.

Physiol Plant 2021 Apr 16. Epub 2021 Apr 16.

Department of Chemistry, Umeå University, Umeå, Sweden.

The growth of the world's population expands the demand for fresh water, food, energy and technology, which on their turn lead to increasing amount of wastewater, produced both by domestic and industrial sources. These different wastewaters contain a huge variety of organic and inorganic compounds, which can cause tremendous environmental problems if released untreated. Traditional treatment systems are usually expensive and energy demanding and often still not capable of facing all challenges presented by the produced wastewaters. Read More

View Article and Full-Text PDF

Interaction of agonists of a different subtype of the nAChR and carvacrol with GABA in somatic muscle contractions.

J Nematol 2021 26;53. Epub 2021 Mar 26.

Faculty of Veterinary Medicine, University of Belgrade, Bul. oslobodjenja 18, 11000, Belgrade, Serbia.

Resistance of parasitic nematodes to anthelmintic drugs is a growing problem in human and veterinary medicine. The molecular mechanisms by which nematodes become resistant are different, but certainly one of the possible processes involves changing the drug binding site on the specific receptor. The significance of changes in individual subtypes of nicotinic acetylcholine receptors (nAChRs) for the development of resistance has not been clarified in detail. Read More

View Article and Full-Text PDF

Hepatic encephalopathy induced by Lenvatinib and anti-PD-1 mAb in a patient with advanced hepatocellular carcinoma: A case report.

Mol Clin Oncol 2021 Jun 1;14(6):110. Epub 2021 Apr 1.

Department of Gastroenterology Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong 250117, P.R. China.

Previous studies have reported that the combinational therapy of Lenvatinib and anti-programmed cell death-1 (PD-1) monoclonal antibody (mAb) produced a longer overall survival in patients with hepatocellular carcinoma (HCC). The current case report presented a a patient with HCC who had hepatic encephalopathy (HE) following treatment with Lenvatinib and anti-PD-1 mAb. The 42-year-old patient was diagnosed with stage IVa HCC accompanied with cirrhosis and Child-Pugh C. Read More

View Article and Full-Text PDF

Four-factor Prothrombin Complex Concentrate for Reversal of Factor Xa Inhibitors versus Warfarin in Life-threatening Bleeding.

West J Emerg Med 2021 Feb 26;22(2):163-169. Epub 2021 Feb 26.

Rush University Medical Center, Department of Pharmacy, Chicago, Illinois.

Introduction: Factor Xa (fXa) inhibitor reversal for life-threatening bleeding is controversial due to a lack of high-quality evidence. The purpose of this study was to determine the hemostatic efficacy of four-factor prothrombin complex concentrate (4F-PCC) for the reversal of fXa inhibitors compared to warfarin for life-threatening bleeding.

Methods: This was a multicenter, retrospective cohort study at two academic medical centers between January 1, 2014-December 31, 2019, which included patients who presented to the emergency department with a life-threatening bleed necessitating anticoagulation reversal with 4F-PCC. Read More

View Article and Full-Text PDF
February 2021

Real-time Base Excision Repair Assay to Measure the Activity of the 8-oxoguanine DNA Glycosylase 1 in Isolated Mitochondria of Human Skin Fibroblasts.

Bio Protoc 2021 Mar 20;11(6):e3954. Epub 2021 Mar 20.

Department of Life Sciences, Albstadt-Sigmaringen University of Applied Sciences, Sigmaringen, Germany.

7,8-dihydro-8-oxoguanine (8-oxoG) is one of the most common and mutagenic oxidative DNA damages induced by reactive oxygen species (ROS). Since ROS is mainly produced in the inner membranes of the mitochondria, these organelles and especially the mitochondrial DNA (mtDNA) contained therein are particularly affected by this damage. Insufficient elimination of 8-oxoG can lead to mutations and thus to severe mitochondrial dysfunctions. Read More

View Article and Full-Text PDF

First Report of Fusarium oxysporum f. sp. lactucae Race 1 Causing Fusarium Wilt of Lettuce in Norway.

Plant Dis 2021 Apr 14. Epub 2021 Apr 14.

NIBIO, 56624, As, Norway;

Lettuce (Lactuca sativa L.) is produced in Norway both in field and greenhouses. In Norway, greenhouse lettuce is one of the most important vegetables grown year-round. Read More

View Article and Full-Text PDF

Powdery Mildew of tall verbena Caused by  in China.

Plant Dis 2021 Apr 14. Epub 2021 Apr 14.

Shangqiu Normal University, 117757, College of biology and food, Shangqiu, Henan 476000, China;

Tall verbena () is widely used in landscape layout in sparse forests, botanical gardens and villa areas, and it is also a kind of Chinese herbal medicine. The flower and bud use as Chinese herbal medicine causing heat-clearing and detoxification. In August 2019, observed on tall verbena in Shangqiu, Henan Province, China. Read More

View Article and Full-Text PDF

Mindfulness and acceptance-based behavioral treatment for bulimia-spectrum disorders: A pilot feasibility randomized trial.

Int J Eat Disord 2021 Apr 14. Epub 2021 Apr 14.

Center for Weight, Eating, and Lifestyle Science, Drexel University, Philadelphia, Pennsylvania, USA.

Objective: Although existing research supports the efficacy of mindfulness- and acceptance-based treatments (MABTs) for eating disorders (EDs), few studies have directly compared outcomes from MABTs to standard CBT.

Method: Participants (N = 44), treatment-seeking adults with bulimia-spectrum EDs, were screened for eligibility, consented, and randomized to receive 20 sessions of outpatient, individual CBT or MABT treatment. Treatment outcomes (binge eating and compensatory behavior episodes, global ED severity, depressive symptoms, quality of life, emotional awareness/clarity, distress tolerance, values-based decision-making, and emotion modulation) were measured at pre-treatment, post-treatment, and 6-month follow up. Read More

View Article and Full-Text PDF

Census of the fruit and flower chafers (Coleoptera, Scarabaeidae, Cetoniinae) of the Macau SAR, China.

Zookeys 2021 25;1026:17-43. Epub 2021 Mar 25.

Macau Anglican College, 109-117 Avenida Padre Tomas Pereira, Taipa, Macau SAR, China Macau Anglican College Macau Macau.

The coleopteran fauna of the Macau SAR in southern China has historically received only limited attention and no updated information has been published since the last substantial works produced in the 1990s. An annotated and illustrated review of the fruit and flower chafers (Scarabaeidae, Cetoniinae) of this region is here presented, in order to provide an account of the current status of the taxonomic diversity and ecology of this important insect group. Eleven species were observed in the SAR during an intense investigation undertaken during the period 2017-2020, with six of these representing new records for Macau and two for the broader region of the Pearl River Delta, also known as the Greater Bay Area. Read More

View Article and Full-Text PDF

Antifungal potential against Sclerotinia sclerotiorum (Lib.) de Bary and plant growth promoting abilities of Bacillus isolates from canola (Brassica napus L.) roots.

Microbiol Res 2021 Apr 2;248:126754. Epub 2021 Apr 2.

Departamento de Genética, Instituto de Biociências, Universidade Federal do Rio Grande do Sul (UFRGS), Av. Bento Gonçalves, 9500, Caixa Postal 15.053, 91501-970, Porto Alegre, RS, Brazil. Electronic address:

Endophytic bacteria show important abilities in promoting plant growth and suppressing phytopathogens, being largely explored in agriculture as biofertilizers or biocontrol agents. Bacteria from canola roots were isolated and screened for different plant growth promotion (PGP) traits and biocontrol of Sclerotinia sclerotiorum. Thirty isolates belonging to Bacillus, Paenibacillus, Lysinibacillus, and Microbacterium genera were obtained. Read More

View Article and Full-Text PDF

Lerf-Klinowski-type models of graphene oxide and reduced graphene oxide are robust in analyzing non-covalent functionalization with porphyrins.

Sci Rep 2021 Apr 12;11(1):7977. Epub 2021 Apr 12.

Institute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224, Warsaw, Poland.

Graphene-based nanohybrids are good candidates for various applications. However, graphene exhibits some unwanted features such as low solubility in an aqueous solution or tendency to aggregate, limiting its potential applications. On the contrary, its derivatives, such as graphene oxide (GO) and reduced graphene oxide (RGO), have excellent properties and can be easily produced in large quantities. Read More

View Article and Full-Text PDF

Nature-Inspired Hierarchical Protrusion Structure Construction for Washable and Wear-Resistant Superhydrophobic Textiles with Self-Cleaning Ability.

ACS Appl Mater Interfaces 2021 Apr 12. Epub 2021 Apr 12.

Fraunhofer USA, Inc., Center Midwest, Division for Coatings and Diamond Technologies, Michigan State University, East Lansing, Michigan 48824, United States.

The use of toxic components and short longevity greatly restricted the commercial application of superhydrophobic surfaces in oil-water separation, antifouling, and self-cleaning. To address these concerns, a durable, robust, and fluorine-free superhydrophobic fabric is prepared on account of inspiration of nature. In this work, submicrometer-sized silica particles with different particle sizes are deposited onto cotton fabrics, followed by hydrophobic modification of poly(dimethylsiloxane) (PDMS), and consequently bonded the substrate and coating via powerful covalent bonds through a simple dip-coating technique. Read More

View Article and Full-Text PDF

Biodegradable Materials for Sustainable Health Monitoring Devices.

ACS Appl Bio Mater 2021 Jan 23;4(1):163-194. Epub 2020 Dec 23.

Bendable Electronics and Sensing Technologies (BEST) Group, James Watt School of Engineering, University of Glasgow, G12 8QQ Glasgow, U.K.

The recent advent of biodegradable materials has offered huge opportunity to transform healthcare technologies by enabling sensors that degrade naturally after use. The implantable electronic systems made from such materials eliminate the need for extraction or reoperation, minimize chronic inflammatory responses, and hence offer attractive propositions for future biomedical technology. The eco-friendly sensor systems developed from degradable materials could also help mitigate some of the major environmental issues by reducing the volume of electronic or medical waste produced and, in turn, the carbon footprint. Read More

View Article and Full-Text PDF
January 2021

Well-to-wake analysis of switchgrass to jet fuel via a novel co-fermentation of sugars and CO.

Sci Total Environ 2021 Mar 27;782:146770. Epub 2021 Mar 27.

Biosystems and Agricultural Engineering, Oklahoma State University, Stillwater, OK, USA.

Lignocellulosic biomass such as switchgrass can be converted to n-butanol using fermentation, which can be further processed into jet fuel. Traditional acetone-butanol-ethanol (ABE) fermentation only converts sugars derived from switchgrass to ABE. Novel co-fermentation processes convert sugars and gas (CO/H) produced during fermentation into butanol, thus increasing ABE yields by 15. Read More

View Article and Full-Text PDF

Toward sustainable remediation of oil sands fine Tailings-A review.

J Environ Manage 2021 Apr 8;288:112418. Epub 2021 Apr 8.

Natural Resources Canada, CanmetENERGY, 1 Oil Patch Drive, Devon, AB T9G 1A8, Canada. Electronic address:

Significant quantities of tailings are produced during the extraction of bitumen from oil sands. Tailings are stored in tailings ponds for several years before they can be appropriately managed. Current fine tailings management approaches include mechanical and/or chemical amendments of fine tailings (FT) to speed up tailings reclamation. Read More

View Article and Full-Text PDF

Techno-functional properties of HoPS from lactic acid bacteria of different origins as potential food additives.

Food Chem 2021 Mar 24;356:129627. Epub 2021 Mar 24.

Centro de Referencia para Lactobacilos (CERELA)-CONICET, Batalla de Chacabuco 145, San Miguel de Tucumán 4000, Tucumán, Argentina. Electronic address:

Homopolysaccharides (HoPS) produced by lactic acid bacteria (LAB) are highly versatile, biocompatible and safe compounds. In this work, six HoPS from different species of Weisella and Leuconostoc were identified as thermally stable dextrans, with endothermic crystalline deformations between 214 and 239 °C. These dextrans proved to have greater solubility and capacities to retain water and oil than similar polymers in other reports. Read More

View Article and Full-Text PDF

Hydrometallurgical enhanced liberation and recovery of anode material from spent lithium-ion batteries.

Waste Manag 2021 Apr 8;126:517-526. Epub 2021 Apr 8.

School of Chemical Engineering & Technology, China University of Mining and Technology, Xuzhou 221116, Jiangsu, China.

The efficient recycling of spent anode material (SAM) from spent lithium-ion batteries (LIBs) is generally critical in terms of electronic waste recyclingas well as increasing resource shortage and environmental problems. This research reported a novel and green method to recycle lithium, copper foil, and graphite from SAM by water leaching treatment. The results indicated that 100% of graphite was exfoliated from the anode material and 92. Read More

View Article and Full-Text PDF

Sewage sludge and solid residues from biogas production derived biochar as an effective bio-waste adsorbent of fulvic acids from water or wastewater.

Chemosphere 2021 Apr 5;278:130447. Epub 2021 Apr 5.

Department of Radiochemistry and Environmental Chemistry, Institute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Skłodowska University, Pl. Marii Curie-Skłodowskiej 3, 20-031, Lublin, Poland.

Due to environmental concern, direct utilization of sewage sludge or residues from biogas production is restricted. Conversion of problematic bio-wastes into biochars can be a very effective solution. In the presented study, the adsorption of fulvic acids onto series of biochars produced from bio-wastes such as sewage sludge, residues from biogas production, and plant (Miscanthus sp. Read More

View Article and Full-Text PDF

Biomass fuel production from cellulosic sludge through biodrying: Aeration strategies, quality of end-products, gaseous emissions and techno-economic assessment.

Waste Manag 2021 Apr 7;126:487-496. Epub 2021 Apr 7.

BETA Technological Center, Science and Technology Faculty, University of Vic-Central University of Catalonia, 08500 Vic, Barcelona, Spain. Electronic address:

This study assesses the technological, environmental and economic feasibility of biodrying to valorise cellulosic sludge as a renewable energy source. Specifically, three different aeration strategies were compared in terms of biodrying performance, energetic consumption, gaseous emissions, quality of end-products and techno-economic analysis. These strategies were based on different combinations of convective drying with biogenic heat produced. Read More

View Article and Full-Text PDF

Serotonergic inhibition of responding for conditioned but not primary reinforcers.

Pharmacol Biochem Behav 2021 Apr 6:173186. Epub 2021 Apr 6.

Global Institutes on Addictions, Miami, FL, United States of America.

Serotonin is widely implicated as a modulator of brain reward function. However, laboratory studies have not yielded a consensus on which specific reward-related processes are influenced by serotonin and in what manner. Here we explored the role of serotonin in cue-reward learning in mice. Read More

View Article and Full-Text PDF

Motif Discovery from CLIP Experiments.

Methods Mol Biol 2021 ;2284:43-50

Centre for Molecular Bioinformatics, Department of Biology, University of Rome Tor Vergata, Rome, Italy.

RNA primary and secondary motif discovery is an important step in the annotation and characterization of unknown interaction dynamics between RNAs and RNA-Binding Proteins, and several methods have been developed to meet the need of fast and efficient discovery of interaction motifs. Recent advances have increased the amount of data produced by experimental assays and there is no available method suitable for the analysis of all type of results. Here we present a simple workflow to help choosing the more appropriate method, depending on the starting situation, among the three algorithms that best cover the landscape of approaches. Read More

View Article and Full-Text PDF
January 2021

[Vocal cord dysfunction in athletes: Interest of rehabilitation to effort].

Rev Mal Respir 2021 Apr 5. Epub 2021 Apr 5.

CIC-CRB 1404, unité de physiologie respiratoire et sportive, centre hospitalier universitaire de Rouen, 1, rue de Germont, 76000 Rouen, France.

Introduction: Vocal Cord Dysfunction (VCD) is a syndrome characterized by paradoxical adduction of the vocal folds during breathing. Its non-specific clinical manifestations frequently lead to misdiagnosis and delay in its treatment. The treatment of VCD is not pharmacological but rehabilitative and remains poorly appreciated. Read More

View Article and Full-Text PDF

Support for an inhibitory model of word retrieval.

Neurosci Lett 2021 Apr 5:135876. Epub 2021 Apr 5.

Department of Psychology, Boston College, United States.

Word retrieval may involve an inhibitory process in which a target word is activated and related words are suppressed. In the current functional magnetic resonance imaging (fMRI) study, we examined the inhibition of language processing cortex by the left dorsolateral prefrontal cortex (DLPFC) during word retrieval using an anagram-solving paradigm. Participants were presented with a distractor that was read aloud followed by a to-be-solved anagram. Read More

View Article and Full-Text PDF

Association between acoustic speech features and non-severe levels of anxiety and depression symptoms across lifespan.

PLoS One 2021 8;16(4):e0248842. Epub 2021 Apr 8.

Institute of Electronics and Informatics Engineering of Aveiro, University of Aveiro, Aveiro, Portugal.

Background: Several studies have investigated the acoustic effects of diagnosed anxiety and depression. Anxiety and depression are not characteristics of the typical aging process, but minimal or mild symptoms can appear and evolve with age. However, the knowledge about the association between speech and anxiety or depression is scarce for minimal/mild symptoms, typical of healthy aging. Read More

View Article and Full-Text PDF

Phosphonates enantiomers receiving with fungal enzymatic systems.

Microb Cell Fact 2021 Apr 7;20(1):81. Epub 2021 Apr 7.

Department of Biochemistry, Molecular Biology and Biotechnology, Laboratory of Biotechnology, Wrocław University of Science and Technology, Wrocław, Poland.

Background: Phosphonates derivatives are in the area of interests because of their unique chemical-physical features. These compounds manifest variety of biological interactions within the sensitive living cells, including impact on particular enzymes activities. Biological "cause and effect" interactions are based upon the specific matching between the structures and/or compounds and this is usually the result of proper optical configurations of particular chiral moieties. Read More

View Article and Full-Text PDF

Reconstructing animated eye movements from electrooculography data to aid the diagnosis of vestibular disorders.

Int J Audiol 2021 Apr 7:1-9. Epub 2021 Apr 7.

University of East Anglia, Norwich, UK.

Objective: To develop a method of visualising electrooculography data to improve the interpretability of nystagmus eye-movements captured using the Continuous Ambulatory Vestibular Assessment (CAVA) device.

Design: We are currently undertaking a clinical investigation to evaluate the capabilities of the CAVA device to detect periods of pathological nystagmus. The work presented here was undertaken using unblinded data obtained from the preliminary phase of this investigation. Read More

View Article and Full-Text PDF

Three-dimensional biomodel use in the surgical management of basilar invagination with congenital cervical scoliosis; correction by unilateral C1-C2 facet distraction.

J Craniovertebr Junction Spine 2020 Oct-Dec;11(4):347-350. Epub 2020 Nov 26.

Department of Spine Surgery, National Institute of Traumatology and Orthopaedics, Rio de Janeiro, Brazil.

Biomodels are produced using three-dimensional printers and their use in complex spine surgeries can be quite helpful, especially when complex anatomy is faced. In this case report, we presented a 14-year-old patient who had rigid congenital cervical scoliosis and basilar invagination and abnormalities on a neurological examination. This patient underwent atlantoaxial facet distraction and C1 C2 fusion while using a biomodel of his craniocervical junction in pre-operative planning and also as an anatomical reference per-operatively. Read More

View Article and Full-Text PDF
November 2020