J Mol Histol 2021 Sep 12. Epub 2021 Sep 12.
Department of Endodontics, College of Stomatology, Tianjin Medical University, Num22, Road Qixiangtai, Heping District, Tianjin, 300070, China.
TRPA1 and TRPV1 channels respond to external stimulation as pain mediators and form a complex with a transmembrane protein TMEM100 in some tissues. However, their expression and interaction in dental pulp is unclear. To investigate the functional co-expression of TRPA1 channel, TRPV1 channel and TMEM100 in human odontoblasts (HODs), immunohistochemistry, immunofluorescence staining and Western blot were used to study their co-localization and expression in both native HODs and cultured HOD-like cells. Read More