Kidney Int 2021 Jun 11. Epub 2021 Jun 11.
Institut National de la Santé et de la Recherche Médicale- Centre de Physiopathologie Toulouse Purpan, Inserm UMR 1043- CNRS 5282, F-31000 Toulouse, France; Université Paul Sabatier Toulouse III, Toulouse, France; Laboratory of Immunology, Biology Department, CHU Toulouse, Toulouse, France.
Solid organ transplant recipients are at high risk for the development of severe forms of COVID-19. However, the role of immunosuppression in the morbidity and mortality of the immune phenotype during COVID-19 in transplant recipients remains unknown. In this retrospective study, we compared peripheral blood T and B cell functional and surface markers, as well as serum antibody development during 29 cases of mild (World Health Organization 9-point Ordinal Scale (WOS) of 3-4) and 22 cases of severe COVID-19 (WOS 5-8) in solid organ transplant (72% kidney transplant) recipients hospitalized in our center. Read More