Search Our Scientific Publications & Authors

Int Braz J Urol 2021 Jul-Aug;47(4):829-840

Department of Urology and Renal Transplantation, JIPMER, Puducherry, India.

Objective: The diagnosis and treatment of female urethral stricture disease (FUSD) are practiced variably due to the scarcity of data on evaluation, variable definitions, and lack of long-term surgical outcomes. FUSD is difficult to rule out solely on the basis of a successful calibration with 14F catheter. In this study, we have tried to characterize the variable clinical presentation of FUSD, the diagnostic utility of calibration, videourodynamic study(VUDS), and urethroscopy in planning surgical management. Read More

Indian J Tuberc 2021 Apr 12;68(2):236-241. Epub 2020 Sep 12.

Infectious Diseases Unit, Prince Sultan Military Medical City (PSMMC), Riyadh, Saudi Arabia.

Objectives: Abdominal tuberculosis (ATB) is the second most common type of extra-pulmonary tuberculosis. Though it does not usually pose a significant risk of infectivity, ATB can go unidentified and progress to disseminated infection. The aim of this study is to highlight the incidence and outcome of this infection in a tertiary care centre in the Kingdom of Saudi Arabia (KSA). Read More

Front Oncol 2021 24;11:639395. Epub 2021 Mar 24.

Department of Endocrinology and Internal Medicine, Medical University of Gdańsk, Gdańsk, Poland.

Background: Renal cell cancer may cause various paraneoplastic syndromes; however, paraneoplastic hypereosinophilia occurs exceedingly rare. Thus far, only two cases of clear cell renal cell carcinoma (CCRCC) associated with hypereosinophilia have been reported. In this paper, we present a case of paraneoplastic hypereosinophilia associated with renal cell carcinoma and a review of the reported cases of hypereosinophilia in solid tumors. Read More

Indian J Nephrol 2020 Nov-Dec;30(6):420-423. Epub 2020 Oct 9.

Department of Nephrology, Centro Hospitalar Lisboa Central EPE, Hospital Curry Cabral, R. Beneficência 8, Lisboa, Portugal.

Nutcracker phenomenon (NCP) refers to compression of the left renal vein (LRV), most frequently between the aorta and the superior mesenteric artery, with impaired blood outflow often accompanied by distention of the distal portion of the vein. The nutcracker syndrome (NCS) is the terminology used when the nutcracker phenomenon is accompanied by a complex of symptoms such as pain (abdominal, flank, and pelvic), hematuria and orthostatic proteinuria. Diagnosis can be made with Doppler ultrasound (DUS), computed tomography (CT), magnetic resonance imaging (MRI), and venography. Read More

Indian J Nephrol 2020 Nov-Dec;30(6):409-415. Epub 2020 Nov 7.

Department of Nephrology, Manipal Hospital, Old HAL Airport Road, Bengaluru, Karnataka, India.

Background: Hypertension is prevalent in 35%-46% of the general population; 1% of them experience accelerated hypertension. Among patients with accelerated hypertension, acute worsening of renal functions occur in 22%-55%. Morbidity and mortality rates are high. Read More

Indian J Nephrol 2020 Nov-Dec;30(6):370-376. Epub 2020 Feb 7.

Department of Pathology, Jaslok Hospital and Medical Research Institute, Mumbai, Maharashtra, India.

Introduction: There is paucity of data of C3 glomerulopathy in Indian children.

Methods: First Indian pediatric case series where consecutive renal biopsies done over a period of ten years were reviewed to identify those patients who had isolated or predominant C3 deposits on immunofluorescent microscopy, fulfilling the criteria for C-3 glomerulopathy. The clinical, biochemical, serological, histopathological profile, eGFR and the need for renal replacement therapy was analyzed. Read More

Jpn J Radiol 2021 Apr 11. Epub 2021 Apr 11.

Department of Maternal and Child Health Research Center, Hiroshima Prefectural Hospital, Hiroshima, Japan.

Hemato/hydrocolpos due to congenital urogenital anomalies are rare conditions discovered in neonatal, infant, and adolescent girls. Diagnosis is often missed or delayed owing to its rare incidence and nonspecific symptoms. If early correct diagnosis and treatment cannot be performed, late complications such as tubal adhesion, pelvic endometriosis, and infertility may develop. Read More

Eur J Trauma Emerg Surg 2021 Apr 11. Epub 2021 Apr 11.

Division of Neurological Surgery, Department of Surgery, Lagos State University Teaching Hospital (LASUTH), Ikeja, Lagos, Nigeria.

Introduction: Chronic subdural haematoma (CSH) has multifactorial mechanisms involved in its development and progression. Identifying readily available inflammatory and coagulation indices that can predict the prognosis of CSH will help in clinical care, prognosis, generating objective criteria for assessing efficacy of treatment strategies and comparisons of treatment efficacy between clinical studies. We conducted a study in which we evaluated the impact value of neutrophil to lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), inflammatory biomarkers (erythrocyte sedimentation rate and C-reactive protein), activated partial thromboplastin time (APTT), prothrombin time (PT) and international normalized ratio (INR) at presentation on CSH severity and outcome using Glasgow outcome scale (GOS), Markwalder grading scale (MGS) and Lagos brain disability examination scale (LABDES). Read More

Int J Surg Case Rep 2021 Apr 1;82:105857. Epub 2021 Apr 1.

S. K. Lerik Public General Hospital, Kupang City, East Nusa Tenggara, Indonesia. Electronic address:

Introduction: Although rare, electrical injury in pediatrics is potentially life threatening and has significant and long-term impact in life. It is challenging to manage such cases in rural areas.

Presentation Of Case: A fully conscious 13-year-old boy was admitted to the emergency room after being electrocuted by high-voltage power cable, with superficial partial thickness burn over right arm, trunk, and left leg (26 % of total body surface area). Read More

Int J Surg Case Rep 2021 Apr 6;82:105867. Epub 2021 Apr 6.

Department of Digestive Surgery, Toulouse University Hospital, 31059, Toulouse, France.

Introduction: Renal cell carcinoma (RCC) represents above 3 % of all cancers. At diagnosis, above 25 % of patients with RCC present an advanced disease. Gastric metastasis of RCC is associated with poor outcome. Read More

Int J Surg Case Rep 2021 Apr 1;82:105849. Epub 2021 Apr 1.

Department of Surgery, Shonan Kamakura General Hospital, Kanagawa, Japan.

Introduction: There are limited reports regarding renal paratransplant hernia (RPH), which is a rare type of internal hernia. Herein, we report a case of successful laparoscopic treatment of RPH.

Presentation Of Case: A kidney transplant recipient presented to our emergency department with a 6-h history of abdominal pain and vomiting. Read More

Cancer Treat Res Commun 2021 Mar 31;27:100367. Epub 2021 Mar 31.

University of Colorado Anschutz Medical Campus, Department of Medicine, Division of Medical Oncology. Electronic address:

Brain metastases from renal cell carcinoma are associated with poor prognosis. Sunitinib is a multi-targeted tyrosine kinase inhibitor used for the treatment of metastatic renal cell carcinoma. It is taken orally on a traditional dosing schedule of 4-week on/2-week off cycles or an alternate dosing schedule of 2-week on/1-week off cycles. Read More

BMC Nephrol 2021 Apr 9;22(1):127. Epub 2021 Apr 9.

Department of Urology, Peking Union Medical College Hospital, Chinese Academy of Science, Beijing, China.

Background: Renal tumors during pregnancy are rare and the treatment requires evaluation of both the patient and the fetus. No consensus or guidelines has been proposed or verified in this field. We successfully managed three renal tumor cases during pregnancy and reviewed the relative literature. Read More

J Bras Nefrol 2021 Apr 9. Epub 2021 Apr 9.

Instituto de Cardiologia do Distrito Federal, Brasília, DF, Brasil.

Introduction: Tuberculosis (TB) is a possible serious complication of solid organ transplantation, associated with high mortality and morbidity. Post-transplant TB has varied pathogenesis with many approaches to its prevention, which is the most important way to reduce its incidence. Treatment of TB in organ recipients is challenging because of drug toxicity and interaction with immunosuppressants. Read More

Pediatr Nephrol 2021 Apr 9. Epub 2021 Apr 9.

Division of Nephrology, Seattle Children's Hospital, Seattle, WA, USA.

Background: Current guidelines for initiation of kidney replacement do not include specific recommendations for prescription parameters and monitoring.

Case Outline: A 16-year-old girl presented with kidney failure with creatinine of 19.8 mg/dL and BUN of 211 mg/dL. Read More

Pediatr Nephrol 2021 Apr 8. Epub 2021 Apr 8.

Hospital Universitario Central de Asturias, Avd. Roma SN, 33011, Oviedo, Spain.

Background: Recent reports indicate that chronic reduction of glomerular filtration rate (GFR) is common in patients with distal renal tubular acidosis (DRTA). Factors responsible for decreased GFR need clarification.

Methods: We reviewed records of 25 patients with genetically confirmed DRTA included in the RenalTube database. Read More

Int Orthop 2021 Apr 9. Epub 2021 Apr 9.

Department of Orthopaedics, School of Clinical Medicine, University of KwaZulu-Natal, Durban, South Africa.

Background: The deleterious effects of hypoalbuminaemia in the peri-operative period are well documented. We aimed to review serum albumin levels in a cohort of orthopaedic trauma patients to determine the prevalence of hypoalbuminaemia. Secondarily, we aimed to identify factors associated with an increased risk of hypoalbuminaemia. Read More

Cureus 2021 Mar 4;13(3):e13697. Epub 2021 Mar 4.

Internal Medicine, Hamad Medical Corporation, Doha, QAT.

Tumor-induced osteomalacia (TIO), otherwise known as oncogenic osteomalacia, is a rare paraneoplastic syndrome, characterized by hypophosphatemia due to decreased tubular reabsorption and low or inappropriately normal level of active vitamin D. The syndrome, first recognized by Robert McCance in 1947, is well described in the medical literature. However, the diagnosis can be delayed due to the nonspecific nature of its presentation. Read More

Am J Forensic Med Pathol 2021 Apr 7. Epub 2021 Apr 7.

From the University of South Carolina School of Medicine, Columbia, SC Edward Via College of Osteopathic Medicine, Auburn, AL Volusia County Medical Examiner's Office, Daytona Beach, FL Pathology Associates of Greenville, Greenville Office of the Medical Examiner, Greenville County University of South Carolina School of Medicine Greenville, Greenville, SC.

Abstract: Atherosclerotic cardiovascular disease (ASCVD) is often investigated by medical examiners as a cause of sudden death. Because of the variation in presentation of atherosclerotic cardiovascular disease, the examiner must be cautious when assigning a final diagnosis. The presented case depended upon histologic examination of coronary artery lesions to reach an appropriate final diagnosis of vasculitis with mixed features. Read More

BMJ Case Rep 2021 Apr 8;14(4). Epub 2021 Apr 8.

Neurology, Kantonsspital Baden, Baden, Switzerland

An 86-year-old woman was diagnosed with hospital-acquired pneumonia with and treated with cefepime adjusted to her renal clearance. After 4 days, she developed acute-onset negative myoclonus without signs of altered mental status. After ruling out an acute intracranial haemorrhagic or ischaemic stroke as well as other metabolic and endocrine causes of negative myoclonus, the antibiotic was switched to piperacillin/tazobactam due to a suspicion of cefepime neurotoxicity. Read More

J Med Case Rep 2021 Apr 9;15(1):154. Epub 2021 Apr 9.

Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-Ku, Chiba-shi, Chiba, 260-8677, Japan.

Background: Mayfield skull clamps are widely used and indispensable in current neurosurgery. Complications such as skull fractures or intracranial hematoma from using a Mayfield skull clamp have largely been reported in the pediatric population, are likely related to the relative thinness of the skull, such as in patients with hydrocephalus, and are extremely rare in adults. Here, we report a case of skull fracture and epidural hematoma caused by a Mayfield skull clamp used for posterior decompression surgery in an adult patient with chronic hemodialysis. Read More

PLoS One 2021 8;16(4):e0249592. Epub 2021 Apr 8.

Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.

Introduction: IgA nephropathy (IgAN) has a heterogeneous presentation and the progression to end stage renal disease (ESRD) is often influenced by demographics, ethnicity, as well as choice of treatment regimen. In this study, we investigated the long term survival of IgAN patients in our center and the factors affecting it.

Methods: This study included all biopsy-proven IgAN patients with ≥ 1year follow-up. Read More

Vet Rec 2021 Jan 24:e72. Epub 2021 Jan 24.

Anderson Moores Veterinary Specialists, Winchester, UK.

Background: One hundred seventy-eight dogs with cutaneous and renal glomerular vasculopathy (CRGV) were evaluated to further the understanding of the natural course of CRGV. CRGV, a form of thrombotic microangiopathy, can cause skin lesions and potentially acute kidney injury (AKI) with a high mortality rate.

Methods: Cases were submitted from multiple practices from 2012 until June 2019. Read More

Front Neurol 2021 22;12:635856. Epub 2021 Mar 22.

Department of Neuropsychiatry, Faculty of Medicine, Aswan University Hospital, Aswan, Egypt.

There is little information on the acute cerebrovascular complications of coronavirus disease 2019 (COVID-19) in Egypt. The aim of this study was to estimate the proportion of acute cerebrovascular disease (CVD) among COVID-19 patients and evaluate their clinical and radiological characteristics in comparison with non-COVID-19 CVD. In a retrospective study, COVID-19 patients whom presented with CVD in Assiut and Aswan University Hospitals were compared with non-COVID-19, CVD patients, admitted to Qena University Hospital, prior to the pandemic. Read More

BMC Urol 2021 Apr 7;21(1):56. Epub 2021 Apr 7.

Department of Urology, Hospital Universitario Ramón Y Cajal. Instituto Ramón Y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.

Background: Xanthogranulomatous pyelonephritis (XGP) is an inflammatory condition of the kidney and its treatment most often involves a combination of antibiotics and nephrectomy. This study aimed to define the clinical features and management of XGP, focusing on microbiological aspects and antibiotic therapy.

Methods: We performed a retrospective study of 27 cases of XGP diagnosed between January 2001 and January 2020 to analyse their clinical and management characteristics. Read More

BMC Nephrol 2021 Apr 7;22(1):122. Epub 2021 Apr 7.

Department of Internal Medicine, Kushiro Red Cross Hospital, 21-14, Shinei-cho, Kushiro, 085-8512, Japan.

Background: Behçet's disease (BD) is a systemic inflammatory vasculitis with both autoimmune and autoinflammatory properties. Renal involvement in BD and its spontaneous remission have been rare. We herein describe a case of parallel disease activity of BD with entero and renal involvements, followed by a spontaneous remission without corticosteroid treatment. Read More

BMC Nephrol 2021 Apr 7;22(1):121. Epub 2021 Apr 7.

Department of Internal Medicine, College of Medicine, Gyeongsang National University, Jinju, South Korea.

Background: The Japanese chaff flower, Achyranthes japonica, is used as complementary medicine to control degenerative arthritis. Although commonly used in South Korea, there has been no report of side effects. We report the first case of acute interstitial nephritis (AIN) that occurred in a woman who ingested A. Read More

Am J Nephrol 2021 Apr 7:1-9. Epub 2021 Apr 7.

Division of Renal Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.

Background: End-stage kidney disease patients on dialysis are particularly susceptible to COVID-19 infection due to comorbidities, age, and logistic constraints of dialysis making social distancing difficult. We describe our experience with hospitalized dialysis patients with COVID-19 and factors associated with mortality.

Methods: From March 1, 2020, to May 31, 2020, all dialysis patients admitted to 4 Emory Hospitals and tested for COVID-19 were identified. Read More

Ocul Immunol Inflamm 2021 Apr 7:1-3. Epub 2021 Apr 7.

The Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Republic of Korea.

: To report a unique case of Stevens-Johnson syndrome (SJS) with severe ocular complications induced by pembrolizumab, an immune checkpoint inhibitor.: A 64-year-old man with urothelial cancer presented with bilateral corneal epithelial defect and conjunctival pseudo-membrane formation with erythematous patches on the four extremities, abdomen, and back. He had urothelial cancer with multifocal lesions in the renal pelvis and left ureter, and para-aortic metastatic lymph nodes. Read More

SA J Radiol 2021 26;25(1):2012. Epub 2021 Feb 26.

Department of Radiodiagnosis, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

Background: The claw sign is advocated as a discriminant of renal versus non-renal origin of tumours. The accuracy of the claw sign on magnetic resonance imaging (MRI) is unknown and is potentially hindered by the inferior spatial resolution and the larger tumour sizes at presentation in developing countries.

Objectives: To define and evaluate the claw sign in differentiating renal from non-renal retroperitoneal masses in children undergoing MRI. Read More