426,049 results match your criteria prepared prepared

Floquet dynamical quantum phase transitions in periodically quenched systems.

J Phys Condens Matter 2021 Jun 15. Epub 2021 Jun 15.

Department of Physics, Ocean University of China, Shandong, Qingdao, 266100, CHINA.

Dynamical quantum phase transitions (DQPTs) are characterized by nonanalytic behaviors of physical observables as functions of time. When a system is subject to time-periodic modulations, the nonanalytic signatures of its observables could recur periodically in time, leading to the phenomena of Floquet DQPTs. In this work, we systematically explore Floquet DQPTs in a class of periodically quenched one-dimensional system with chiral symmetry. Read More

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Emission tuning of highly efficient quaternary Ag-Cu-Ga-Se/ZnSe quantum dots for white light-emitting diodes.

J Colloid Interface Sci 2021 May 23;602:307-315. Epub 2021 May 23.

Institute for Electric Light Sources, School of Information Science and Technology, Fudan University, Shanghai 200433, China; Institute of Future Lighting, Academy for Engineering and Technology, Fudan University, Shanghai 200433, China; Zhongshan - Fudan Joint Innovation Center, Zhongshan 528437, China. Electronic address:

With the blooming development of zero-dimensional nanomaterials, I-III-VI alloying quantum dots (QDs) with outstanding photoelectrical properties have emerged to attract much attention as promising environmentally-friendly substitutions for conventional binary Cd-based QDs. In this work, a facile one-pot method was introduced to synthesize unreported quaternary Ag-Cu-Ga-Se/ZnSe (ACGSe/ZnSe) QDs. A relatively high photoluminescence quantum yield (PL QY) of 71. Read More

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Nitrogen-carbon materials base on pyrolytic graphene hydrogel for oxygen reduction.

J Colloid Interface Sci 2021 Jun 8;602:274-281. Epub 2021 Jun 8.

Lab of Advanced Nano-structures & Transfer Processes, Department of Chemical Engineering, Tianjin University, Tianjin 300354, China; Chemistry and Chemical Engineering Guangdong Laboratory, Shantou 515031 China. Electronic address:

Hypothesis: Oxygen reduction reaction (ORR) has played a significant role in the utilization of energy nowadays. Nitrogen-doped carbon materials are seen as promising catalysts for ORR, so it is of great significance in studying the functions of different nitrogen moieties.

Experiments: The graphene hydrogel-based nitrogen-arbon materials (GH N-C) were fabricated by first obtaining a gel through hydrothermal treatment using graphene oxide (GO) as precursor, and then calcined in an ammonia atmosphere at different temperatures to form N-doped graphitized materials with divers nitrogen configuration. Read More

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Synergistic adsorption and degradation of sulfamethoxazole from synthetic urine by hickory-sawdust-derived biochar: The critical role of the aromatic structure.

J Hazard Mater 2021 Jun 9;418:126366. Epub 2021 Jun 9.

Department of Civil Engineering, University of Louisiana at Lafayette, Lafayette, LA, 70504, USA; Energy Institute of Louisiana, University of Louisiana at Lafayette, Lafayette, LA, 70504, USA. Electronic address:

This study investigated the adsorptive removal and subsequent degradation of sulfamethoxazole (SMX) from a synthetic urine by biochar (BC). The BCs used in this study were prepared using two different feedstocks with different temperatures. Element analysis and Fourier transform infrared spectroscopy (FTIR) results suggested that the aromaticity of one of the BCs, 700HSBC was significantly different from the 700PSBC although both of them were prepared at the same temperature (700 °C) with similar pore size distributions and specific surface areas. Read More

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Efficient heavy metal removal from water by alginate-based porous nanocomposite hydrogels: The enhanced removal mechanism and influencing factor insight.

J Hazard Mater 2021 Jun 8;418:126358. Epub 2021 Jun 8.

School of Hydraulic Engineering, Changsha University of Science & Technology, Changsha 410114, China; Key Laboratory of Dongting Lake Aquatic Eco-Environmental Control and Restoration of Hunan Province, Changsha 410114, China. Electronic address:

Novel porous alginate-based nanocomposite hydrogels were prepared by incorporating polyaniline-polypyrrole modified graphene oxide ([email protected]) as reinforcing fillers into the alginate matrix ([email protected]/SA) for Cr(VI) and Cu(II) removal from water. Different in-situ co-polymerization functionalized GO with Py-to-An mass ratios of monomers (from nil to 1:1) and contents of [email protected] (from nil to 2.0%(w/v)) were embedded into the alginate backbone to improve the sorption performance. Read More

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Removal of trace DNA toxic compounds using a Poly(deep eutectic solvent)@Biomass based on multi-physical interactions.

J Hazard Mater 2021 Jun 9;418:126369. Epub 2021 Jun 9.

College of Pharmaceutical Science, Institute of Life Science and Green Development, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Hebei University, Baoding 071002, China. Electronic address:

DNA toxic compounds (DNA-T-Cs), even in trace amounts, seriously threaten human health and must be completely eliminated. However, the currently used separation media face great challenges in removing trace DNA-T-Cs. Based on the functional advantages of deep eutectic solvents (DESs) and the natural features of biomass (BioM), a series of Poly(DES)@BioMs functioning as adsorbents were prepared for the removal of aromatic/hetero-atomic DNA-T-Cs at the ppm level. Read More

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Glioblastoma-specific anticancer activity of newly synthetized 3,5-disubstituted isoxazole and 1,4-disubstituted triazole-linked tyrosol conjugates.

Bioorg Chem 2021 Jun 8;114:105071. Epub 2021 Jun 8.

University of Monastir, Faculty of Science of Monastir, Laboratory of Heterocyclic, Chemistry, Natural Products and Reactivity, TeamMedicinal Chemistry and Natural, Products (LR11ES39), Department of Chemistry, Avenue of Environment, 5019 Monastir, Tunisia. Electronic address:

Two series of 3,5-disubstituted isoxazoles (6a-e) and 1,4-disubstituted triazoles (8a-e) derivatives have been synthesized from tyrosol (1), a natural phenolic compound, detected in several natural sources such as olive oil, and well-known by its wide spectrum of biological activities. Copper-catalyzed microwave-assisted 1,3-dipolar cycloaddition reactions between tyrosol-alkyne derivative 2 and two series of aryl nitrile oxides (5a-e) and azides (7a-e) regiospecifically afforded 3,5-disubstituted isoxazoles (6a-e) and 1,4-triazole derivatives (8a-e), respectively in quantitative yields. Synthesized compounds were purified and characterized by spectroscopic means including 1D and 2D NMR techniques and HRMS analysis. Read More

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Lactoferrin-ginsenoside Rg3 complex ingredients: Study of interaction mechanism and preparation of oil-in-water emulsion.

Food Chem 2021 May 29;363:130239. Epub 2021 May 29.

College of Food Science and Engineering, Jilin University, Changchun 130062, Jilin, China. Electronic address:

Revealing the interaction mechanism between bovine lactoferrin (LF) and 20(S)-ginsenoside Rg3 (Rg3), thereby introducing Rg3 to LF and even into stable emulsions will contribute significantly to food valorization and food industry. Adding Rg3 to LF caused slight absorbance increment and static fluorescence quench of LF, implying the successful combination. Synchronous fluorescence, three-dimensional fluorescence and circular dichroism spectroscopy indicated the conformation changing of LF after binding with Rg3. Read More

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Facile and rapid detection of SARS-CoV-2 antibody based on a noncompetitive fluorescence polarization immunoassay in human serum samples.

Biosens Bioelectron 2021 Jun 5;190:113414. Epub 2021 Jun 5.

Division of Applied Chemistry, Faculty of Engineering, Hokkaido University, Kita 13 Nishi 8, Kita-ku, Sapporo, 060-8628, Japan; Innovative Research Centre for Preventive Medical Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan; Institute of Innovation for Future Society, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan. Electronic address:

Antibody detection methods for viral infections have received broad attention due to the COVID-19 pandemic. In addition, there remains an ever-increasing need to quantitatively evaluate the immune response to develop vaccines and treatments for COVID-19. Here, we report an analytical method for the rapid and quantitative detection of SARS-CoV-2 antibody in human serum by fluorescence polarization immunoassay (FPIA). Read More

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Effect of chlorhexidine-loaded poly(amido amine) dendrimer on matrix metalloproteinase activities and remineralization in etched human dentin in vitro.

J Mech Behav Biomed Mater 2021 Jun 10;121:104625. Epub 2021 Jun 10.

Stomatological Hospital of Chongqing Medical University, Chongqing, 401147, China. Electronic address:

To investigate the effect of chlorhexidine (CHX)-loaded carboxyl-terminated poly (amido amine) dendrimer (CHX-PAMAM-COOH) on matrix metalloproteinase (MMP) activities and remineralization in human dentin, CHX-PAMAM-COOH was prepared and characterized by Fourier-transform infrared spectroscopy. The inhibitory effects of CHX, PAMAM-COOH, and CHX-PAMAM-COOH on soluble recombinant human matrix metalloproteinase (rhMMP-2) and dentin-bound endogenous MMP activity were measured using an MMP Activity Assay Kit. In situ zymography was performed to evaluate the gelatinase activity in dentin pretreated with CHX, PAMAM-COOH, and CHX-PAMAM-COOH. Read More

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Methodology for altering omega-3 EPA+DHA and omega-6 linoleic acid as controlled variables in a dietary trial.

Clin Nutr 2021 May 12;40(6):3859-3867. Epub 2021 May 12.

Department of Neurology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Background & Aims: Increasing dietary intake of n-3 EPA+DHA and lowering dietary n-6 LA is under investigation as a therapeutic diet for improving chronic pain syndromes as well as other health outcomes. Herein we describe the diet methodology used to modulate intake of n-3 and n-6 PUFA in a free living migraine headache population and report on nutrient intake, BMI and diet acceptability achieved at week 16 of the intensive diet intervention and week 22 follow-up time-point.

Methods: A total of 178 participants were randomized and began one of three diet interventions: 1) a high n-3 PUFA, average n-6 PUFA (H3) diet targeting 1500 mg EPA+DHA/day and 7% of energy (en%) from n-6 linoleic acid (LA), 2) a high-n-3 PUFA, low-n-6 PUFA (H3L6) targeting 1500 mg EPA+DHA/day and <1. Read More

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Analysis of neurosurgical cases before and during the COVID-19 pandemic from a tertiary care centre in India.

World Neurosurg 2021 Jun 12. Epub 2021 Jun 12.

Professor, Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi India.

Objective: We present the unique administrative issues as well as specific patient and surgeon related challenges and solutions implemented while treating neurosurgical cases during the COVID pandemic vis-à-vis the pre COVID times at our tertiary care center.

Methods: This is a retrospective study comparing the outcome of the neurosurgical patients treated from the beginning of lockdown in India on 25 March 2020 to 30 November 2020 with that of same period in the previous year, 2019.

Results: We had a total of 687 admissions under neurosurgery this year during the study period as compared to 2550 admissions in 2019. Read More

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Ultrasound-assisted CF-filled PLGA nanobubbles for enhanced FGF21 delivery and improved prophylactic treatment of diabetic cardiomyopathy.

Acta Biomater 2021 Jun 12. Epub 2021 Jun 12.

Department of Ultrasound in Medicine, Shanghai Institute of Ultrasound in Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yishan Road, Shanghai 200233, P.R. China.; Department of Ultrasound in Medicine, Shanghai Eighth People's Hospital, 8 Caobao Road, Shanghai 200235, P.R. China.

Diabetic cardiomyopathy (DCM) is a serious cardiac complication of diabetes that currently lacks specific treatment. Fibroblast growth factor 21 (FGF21) has been proved to have cardioprotective effect in DCM. However, the insufficient cardiac delivery effect of FGF21 limits its application in DCM. Read More

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Reconstituted mRNA Covid-19 vaccines may maintain stability after continuous movement.

Clin Microbiol Infect 2021 Jun 12. Epub 2021 Jun 12.

Laboratory of Neuropharmacology-Neurophar, Department of Experimental and Health Sciences, Universitat Pompeu Fabra (UPF), Barcelona, Spain; Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain. Electronic address:

Objectives: There is an urgent need to ameliorate the possibilities to transport the reconstituted mRNA vaccines from the centralized preparation centers to the vaccination sites to improve the COVID-19 vaccination campaigns. We have analyzed Pfizer-BioNTech and Moderna vaccine integrity under different movement conditions to provide information that may improve the distribution of vaccines to the target population.

Methods: Syringes of reconstituted Pfizer-BioNTech or Moderna COVID-19 vaccines were prepared in a laminar flow chamber to be subjected to a stability analysis in order to evaluate the impact of movement conditions on mRNA integrity. Read More

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Eggshells biowaste for hydroxyapatite green synthesis using extract piper betel leaf - Evaluation of antibacterial and antibiofilm activity.

Environ Res 2021 Jun 12;200:111493. Epub 2021 Jun 12.

School of Renewable Energy, Maejo University, Chiang Mai, 50290, Thailand; College of Medical and Health Science, Asia University, Taichung, Taiwan. Electronic address:

The present research work reports the biosynthesis of hydroxyapatite (HAp) from eggshells and green synthesis of HAp from eggshells with incorporation of Piper betel leaf extract (PBL-HAp) using microwave conversion method. Although there are several works on synthesis of HAp from eggshells and other calcium and phosphorus rich substrates, the incorporation of herbal extract with HAp to promote antimicrobial and antibiofilm activity is less explored and reported. This research work highlights a simple and cost-effective method for development of antimicrobial biomaterials by combining the concepts of waste management, biomaterial science, and herbal medicine. Read More

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Chemoattractants driven and microglia based biomimetic nanoparticle treating TMZ-resistant glioblastoma multiforme.

J Control Release 2021 Jun 12;336:54-70. Epub 2021 Jun 12.

Department of Pharmaceutics, School of Pharmacy, Air Force Medical University, Xi'an 710032, China. Electronic address:

Currently, clinical treatment for temozolomide (TMZ)-resistant glioblastoma multiforme (GBM) is still a difficult problem. The aim of this paper is to set up a new GBM-targeted drug delivery system to treat TMZ-resistant GBM. Zoledronate (ZOL) not only induces apoptosis of TMZ-resistant GBM cells by down-regulation of farnesyl pyrophosphate synthetase (FPPS) but also increases the proportion of M1-type GBM associated macrophages (GAM). Read More

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A Fluorescence Sensor Array Based on Zinc(II)-carboxyamidoquinolines: Toward Quantitative Detection of ATP.

Chemistry 2021 Jun 15. Epub 2021 Jun 15.

BGSU: Bowling Green State University, Chemistry, UNITED STATES.

The newly prepared fluorescent carboxyamidoquinolines ( 1 - 3 ) and their Zn(II) complexes ( [email protected] - [email protected] ) were used to bind and sense various phosphate anions utilizing a relay mechanism, in which the Zn(II) ion migrates from the [email protected] - [email protected] complexes to the phosphate, namely adenosine 5'-triphosphate (ATP) and pyrophosphate (PPi), a process accompanied by a dramatic change in fluorescence. [email protected] - [email protected] assemblies bind adenine nucleotide phosphates while displaying an analyte-specific response. This process was investigated using UV-vis, fluorescence and NMR spectroscopy. Read More

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Autophagy activity in cholangiocarcinoma is associated with anatomical localization of the tumor.

PLoS One 2021 15;16(6):e0253065. Epub 2021 Jun 15.

2nd Department of Pathology, Semmelweis University, Budapest, Hungary.

The presence of autophagy has been indicated in cholangiocarcinoma (CC), which disease has poor prognosis and limited treatment options. Recently, CC has been classified by anatomical localization as intrahepatic (iCC), perihilar (pCC) and distal (dCC), showing different clinical and molecular characteristics. Thus, our aim was to compare autophagy activity in CC samples resected from different anatomical locations. Read More

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Removal of triclosan from water by sepiolite supported bimetallic Fe/Ni nanoparticles.

Environ Technol 2021 Jun 15:1-10. Epub 2021 Jun 15.

Institute of Environmental pollution and health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai, People's Republic of China.

A simple and low-cost route to fabricate sepiolite-supported bimetallic Fe/Ni (Sep-Fe/Ni) nanoparticles was obtained by synchronous liquid phase reduction method. The as prepared composite was used to remove triclosan (TCS) from aqueous solutions. X-ray diffraction, scanning electron microscopy, transmission electron microscopy, and Brunauer-Emmett-Teller (BET) analysis were used for characterization of the materials. Read More

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Elena Alexandrovna Timofeeva-Resovskaya at the forefront of radiobiology in the XX century.

S N Kulikov

Int J Radiat Biol 2021 Jun 15:1-25. Epub 2021 Jun 15.

Ural State Medical University, Human Anatomy, Ekaterinburg, Repina, 3, Human Anatomy Department, to Kulikov S.N., Ekaterinburg, 620028 Russian Federation.

The purpose of the work was to show the outstanding contribution of Elena Alexandrovna Timofeeva-Resovskaya (1898-1973) to the development of radiobiology. This article was prepared on the basis of the author's memoirs, using materials from the personal archive, as well as literary and electronic sources. For the first time the autobiography of Elena A. Read More

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Efavirenz Loaded Mixed Polymeric Micelles: Formulation, Optimization, and Characterization.

Assay Drug Dev Technol 2021 Jun 14. Epub 2021 Jun 14.

Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo, New South Wales, Australia.

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First Report of Leaf Spot Caused by Ramularia sphaeroidea on Vicia villosa var. glabrescens in China.

Plant Dis 2021 Jun 15. Epub 2021 Jun 15.

Lanzhou University, College of Pastoral Agriculture Science and Technology, No. 768, Jiayuguan West Road, Lanzhou, Gansu, China, 730020.

Hairy vetch is widely grown in southwestern China for green manure and forage. In December 2019, a leaf disease occurred on 80% plants of in an eight-hectare field in Qujing(N 25°28'12″, E 103°36'22″), Yunnan Province, China. The disease leaves had irregular, brown to dark brown leaf spots with white mold. Read More

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First Report of Brown Spot Needle Blight on Pinus thunbergii Parl. Caused by Aureobasidium pullulans in China.

Plant Dis 2021 Jun 15. Epub 2021 Jun 15.

Nanjing Forestry University, 74584, College of Forestry, 159 Longpan Road, Nanjing, China, 210037;

Pinus thunbergii Parl., known as black pine, is widely distributed all over China. This pine variety can prevent soil desertification and promote soil conservation and is excellent for constructing fast-growing forests and shelter belts. Read More

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Convenient and large-scale fabrication of cost-effective superhydrophobic aluminum alloy surface with excellent reparability.

Langmuir 2021 Jun 15. Epub 2021 Jun 15.

School of Chemical Engineering and Technology, Xi'an Jiaotong University, Xi'an 710049, China.

Superhydrophobic surfaces are widely used in industry and daily life, yet their practical application is limited by their complicated preparation process, high cost, and poor repairability. We propose a low-cost, facile process for preparing superhydrophobic surfaces to address this limitation. Through a simple three-step spraying process, the rough structure was first constructed on the aluminum alloy, and upon modification by modifier, the superhydrophobic aluminum alloy surface was successfully prepared. Read More

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Photoacid Generators Activated through Sequential Two-Photon Excitation: 1-Sulfonatoxy-2-alkoxyanthraquinone Derivatives.

J Phys Chem A 2021 Jun 15. Epub 2021 Jun 15.

Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland 20742, United States.

Two sulfonate ester derivatives of anthraquinone, 1-tosyloxy-2-methoxy-9,10-anthraquinone () and 1-trifluoromethylsulfonoxy-2-methoxy-9,10-anthraquinone (), were prepared and their ability to produce strong acids upon photoexcitation was examined. It is shown that these compounds generate acid with a yield that increases with light intensity when the applied photon dose is held constant. Additional experiments show that the rate of acid generation increases fourfold when visible light (532 nm) laser pulses are combined with ultraviolet (355 nm) compared with ultraviolet alone. Read More

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Amphiphilic Near-IR-Emitting 3,5-(2-Pyrrolylethenyl)BODIPY Derivatives: Synthesis, Characterization, and Comparison with Other (Hetero)Arylethenyl-Substituted BODIPYs.

J Org Chem 2021 Jun 15. Epub 2021 Jun 15.

Department of Chemistry and Biochemistry, University of Maryland, Baltimore County, 1000 Hilltop Circle, Baltimore 21250, Maryland, United States.

A series of 3,5-(hetero)arylethenyl-substituted BODIPY derivatives have been prepared by Knoevenagel-type condensation of alkyl-substituted BODIPY with the corresponding aldehydes. 2-Pyrrolylethenyl-substituted derivatives feature near-IR emission (λ > 700 nm) with a high fluorescence quantum yield. Both the emission maxima and fluorescence quantum yields are relatively insensitive to solvent polarity, contrary to the corresponding near-IR-emitting 4-(,-dimethylaminophenyl)ethenyl derivatives. Read More

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Photoinduced Reversible Semicrystalline-to-Amorphous State Transitions of Stereoregular Azopolyesters.

Angew Chem Int Ed Engl 2021 Jun 15. Epub 2021 Jun 15.

Dalian University of Technology, State Key Laboratory of Fine Chemicals, CHINA.

Precise control over both the chirality and sequence of a synthetic polymer is critical for manipulating its material performance. Herein, we report the synthesis of a variety of isotactic azobenzene-based polyesters (azopolyesters) with main-chain chirality via highly enantioselective resolution copolymerization of racemic azobenzene-containing epoxides with cyclic anhydrides, using an enantiopure binuclear catalyst system. All the prepared polyesters bearing trans -azobenzene moieties were found to be typical semicrystalline materials with melting temperatures in the range of 153 to 231 °C, while the corresponding isotactic cis -azopolyesters were amorphous. Read More

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Influence of Iron Sulfide Nanoparticle Sizes in Solid-State Batteries.

Angew Chem Int Ed Engl 2021 Jun 15. Epub 2021 Jun 15.

Westfalische Wilhelms-Universitat Munster, Institute für Anorganische und Analytische Chemie, Correnstrasse 30, 48149, Münster, GERMANY.

Given the inherent performance limitations of intercalation-based lithium-ion batteries, solid-state conversion batteries are promising systems for future energy storage. A high specific capacity and natural abundancy make iron disulfide (FeS 2 ) a promising cathode active material. In this work, FeS 2  nanoparticles were prepared solvothermally. Read More

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Reductive and adsorptive elimination of U(VI) ions in aqueous solution by [email protected] composites.

Environ Sci Pollut Res Int 2021 Jun 15. Epub 2021 Jun 15.

School of Life Science, Shaoxing University, Shaoxing, 312000, People's Republic of China.

The novel biochar supported by starch and nanoscale iron sulfide ([email protected]) composites were successfully prepared through coupling of biochar derived from peanut shell with nanoscale ferrous sulfide and starch under nitrogen atmosphere. It had the advantages of biochar, starch, and nanoscale ferrous sulfide. Therefore, it could overcome some shortcomings. Read More

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Bi-polymeric Spongy Matrices Through Cross-linking Polymerization: Synthesized and Evaluated for Solubility Enhancement of Acyclovir.

AAPS PharmSciTech 2021 Jun 15;22(5):181. Epub 2021 Jun 15.

Department of Pharmaceutics, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Punjab, Pakistan.

In this study, two hydrophilic polymers hydroxypropyl methyl cellulose and beta-cyclodextrin (β-CD) are used to synthesize highly responsive and spongy polymeric matrices. Porous and stimulus-responsive polymeric network was developed to improve the solubility of acyclovir (ACV) at significant level. Grafting was successfully carried out by free radical polymerization technique. Read More

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