135,528 results match your criteria pregnant women


Frequency of unscheduled visits to the Obstetrical Triage Assessment unit by pregnant adolescents in an urban Canadian Center compared to a matched cohort of pregnant women.

J Obstet Gynaecol Can 2022 Jun 22. Epub 2022 Jun 22.

Division of Pediatric and Adolescent Gynecology, Department of Surgery, Children's Hospital of Eastern Ontario; University of Ottawa, Department of Obstetrics and Gynecology, Ottawa, Canada; Clinical Research Unit, Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada; Ottawa Hospital Research Institute, Ottawa, Canada.

Objectives: People from marginalized and vulnerable populations present more frequently for unscheduled, emergency obstetrical services at labour and delivery triage units. Based on our clinical experience, pregnant adolescents visit the obstetrical triage assessment units (OTAU) more often than adults do. This study was designed to assess this phenomenon by quantifying and describing the frequency of unscheduled visits to the OTAU by pregnant adolescents (age <20 y) compared with a matched cohort of adult pregnant patients (age ≥20 y). Read More

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Environmental exposure to per- and polyfluoroalkyl substances and sleep disturbance in pregnant women: A prospective cohort study.

Sci Total Environ 2022 Jun 22:156869. Epub 2022 Jun 22.

Ministry of Education-Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang Road, Shanghai 200092, China; School of Public Health, Shanghai Jiao Tong University School of Medicine, 227 South Chongqing Road, Shanghai 200052, China. Electronic address:

Previous studies on the association between exposure to per- and polyfluoroalkyl substances (PFAS) and sleep patterns in pregnant women are limited. This cohort study aims to assess the associations between PFAS and sleep quality in pregnant women. Of the 4127 women who participated in the Shanghai Birth Cohort, 3174, 3070, and 2887 women in their first, second, and third trimesters of gestation, respectively, were included in our analysis. Read More

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The relationship between adverse childhood experiences and common mental disorders among pregnant women living with HIV in Malawi.

J Affect Disord 2022 Jun 22. Epub 2022 Jun 22.

Baylor College of Medicine Children's Foundation Malawi, Tingathe Outreach Community Program, Lilongwe, Malawi; Baylor International Pediatric AIDS Initiative at Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.

Introduction: Adverse childhood experiences (ACEs) have been linked to common mental disorders (CMDs) such as anxiety and depressive thoughts. We examined the prevalence of ACEs and their association with CMDs among pregnant women living with HIV (PWLHIV) in Malawi-an HIV endemic resource-limited setting.

Methods: This is a cross-sectional study of 798 PWLHIV enrolled in the VITAL Start trial in Malawi (10/2018 to 06/2021) (NCT03654898). Read More

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In missed abortion the decrease of IGF-1 down-regulates PI3K/AKT signaling pathway reducing the secretion of progesterone and β-hCG.

Growth Horm IGF Res 2022 Jun 14;65:101479. Epub 2022 Jun 14.

Institute of Maternal, Child and Adolescent Health, School of Public Health, Lanzhou University, Lanzhou 730000, China. Electronic address:

Objective: To explore whether the reduction of IGF-1 in missed abortion down-regulates PI3K/AKT signaling pathway, thereby causing trophoblast cell apoptosis and reducing the secretion of β-hCG and progesterone.

Design: 12 pairs of serum and villous tissues were selected from missed abortion patients and normal early pregnant women who had terminated pregnancy by artificial abortion. The subjects in two groups had same age and gestational week. Read More

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The effect of phthalates exposure during pregnancy on asthma in infants aged 0 to 36 months: a birth cohort study.

Environ Geochem Health 2022 Jun 25. Epub 2022 Jun 25.

Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, 230032, Anhui, China.

This cohort study sought to investigate the effects of phthalates exposure during pregnancy on offspring asthma and its association with placental stress and inflammatory factor mRNA expression levels. A total of 3474 pregnant women from the China Ma'anshan birth cohort participated in this study. Seven phthalate metabolites were detected in urine samples during pregnancy by solid phase extraction-high-performance liquid chromatography tandem mass spectrometry. Read More

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Differential effects of delayed cord clamping on bilirubin levels in normal and diabetic pregnancies.

Eur J Pediatr 2022 Jun 25. Epub 2022 Jun 25.

Department of Obstetrics and Gynecology, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325027, China.

The purpose of the study is to investigate the effects of delayed cord clamping on bilirubin levels and phototherapy rates in neonates of diabetic mothers. This was a prospective study that enrolled pregnant women without pregnancy complications and those with diabetes. Their neonates were randomized in a 1:1 ratio to delayed cord clamping. Read More

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An Emerging Pattern? A Further Case of Anticipated Capacity Loss in Pregnancy: North Middlesex University Hospital NHS Trust V SR [2021] EWCOP 58.

Authors:
Aimee V Hulme

Med Law Rev 2022 Jun 25. Epub 2022 Jun 25.

School of Law and Social Justice, University of Liverpool, Liverpool L69 7ZR, UK.

In 2021, the Court of Protection made a third anticipatory declaration that it was lawful for a capacitous pregnant woman to be subject to possible forcible treatment contingent on her losing capacity before or during birth. North Middlesex University Hospital v SR raises three interesting questions for discussion which this commentary will explore. First, it is submitted that there is a growing, yet alarming, trend in the use of anticipatory or contingent declarations to manage such challenging cases of future loss of, or fluctuating, capacity in pregnant women. Read More

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Expression and role of miR-146a and SMAD4 in placental tissue of pregnant women with preeclampsia.

J Obstet Gynaecol Res 2022 Jun 25. Epub 2022 Jun 25.

Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.

Introduction: To investigate the expression of miR-146a in severe preeclampsia (PE) and its effect on trophoblast cell proliferation, invasion and apoptosis, as well as its relationship with SMAD4.

Material And Methods: Participants were divided into the severe PE group (n = 30) and the normal group (n = 30). The expression of miR-146a and SMAD4 in placenta tissue was detected by immunohistochemistry, qRT-PCR, and western blot. Read More

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Low-dose aspirin for prevention of preeclampsia: Implementation of the NICE guideline in Thailand.

J Obstet Gynaecol Res 2022 Jun 24. Epub 2022 Jun 24.

Department of Obstetrics and Gynecology, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.

Aim: To evaluate the effectiveness of a preeclampsia (PE) screening program using the National Institute for Health and Care Excellence (NICE) guideline in pregnant Thai women.

Methods: A total of 2552 pregnancies received antenatal care and were delivered at Songklanagarind Hospital between November 2016 and April 2020. PE screening with the NICE guideline was used to identify mothers at risk. Read More

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Minding the Baby versus usual care: study protocol for a quasi-cluster-randomized controlled study in Denmark of an early interdisciplinary home-visiting intervention for families at increased risk for adversity.

Trials 2022 Jun 24;23(1):529. Epub 2022 Jun 24.

Yale Child Study Center, 230 S Frontage Rd, New Haven, CT, USA.

Background: Inequality in health can have profound effects on a child's opportunities later in life. To prevent these downstream effects in families at increased risk of adversity, programs are needed to provide support and improve well-being across several domains. The present trial is aimed at assessing the effectiveness of the Minding the Baby® (MTB) home visiting intervention in improving the mother-child relationship, parental reflective functioning, well-being, and mental health, as well as child development and well-being in families at known risk of adverse health, relational, and developmental outcomes. Read More

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How are women with a disability identified in maternity services in Australia? A cross-sectional survey of maternity managers.

Women Birth 2022 Jun 21. Epub 2022 Jun 21.

Judith Lumley Centre, La Trobe University, Bundoora, VIC 3086, Australia; School of Nursing & Midwifery, La Trobe University, Bundoora, VIC 3086, Australia.

Background: Women with a disability have poorer perinatal outcomes, but little is known about the prevalence of women with a disability accessing maternity services, how they are identified and what care and services are available. Estimates suggest that nine percent of women of childbearing age have a disability.

Aim: To explore how public maternity services in Australia identify pregnant women with a disability, what (if any) routine disability identification questions are used, and to examine availability and adequacy of services for women. Read More

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American College of Preventive Medicine: Addressing the Opioid Epidemic Through a Prevention Framework.

Am J Prev Med 2022 Jun 21. Epub 2022 Jun 21.

Department of Family Medicine and Community Health, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin.

The opioid epidemic has resulted in significant morbidity and mortality in the U.S. Health systems, policymakers, payers, and public health have enacted numerous strategies to reduce the harms of opioids, including opioid use disorder (OUD). Read More

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WHO's support for COVID-19 research and knowledge management in the Eastern Mediterranean Region.

BMJ Glob Health 2022 Jun;7(Suppl 3)

Department of Science, Information and Dissemination, WHO Regional Office for the Eastern Mediterranean, Cairo, Egypt.

Health research, innovation and knowledge management remain major priorities of the WHO's response to the COVID-19 pandemic. WHO's Eastern Mediterranean Regional Office (EMRO) supports priority research initiatives that address gaps in current knowledge regarding the COVID-19 pandemic. Through a specific call for proposals, 122 research proposals were received and reviewed in 2020, of which 17 were recommended for funding from eight countries. Read More

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Impaired fasting glucose in pregnancy: improved perinatal outcomes with active glycemic management.

Am J Perinatol 2022 Jun 24. Epub 2022 Jun 24.

Perinatology, Kaiser Permanente Oakland Medical Center, Oakland, United States.

Objective: To assess the association between active glycemic management and large for gestational age (LGA) neonates and cesarean delivery (CD) among pregnant women with impaired fasting glucose (IFG).

Study Design: Retrospective cohort study using electronic health record data of women with IFG who delivered at Kaiser Permanente Northern California from 2012-2017. IFG was defined as isolated fasting glucose ≥95 mg/dL. Read More

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Being a mother under the COVID-19 pandemic lockdown: Evaluation of perinatal anxiety, prenatal attachment, and maternal-infant attachment.

Am J Perinatol 2022 Jun 24. Epub 2022 Jun 24.

Obstetrics and Gynecology, TC Saglik Bakanligi Izmir Il Saglik Mudurlugu Izmir Saglik Bilimleri Universitesi Tepecik Egitim ve Arastirma Hastanesi, Izmir, Turkey.

Objectives: The COVID-19 pandemic has caused both physical and emotional stress throughout the population due to its worldwide impact. The unknowns about the disease, the social isolation, and pregnant women's concerns regarding exposure to the COVID-19, inaccessibility to necessary care, and the possibility of harm to their fetus, may cause increased psychological distress during the perinatal period. We aimed to evaluate the association between perinatal anxiety, prenatal attachment, and maternal-infant attachment status among women with those who delivered their child in a tertiary care center with rigid hospital restrictions. Read More

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Maternal obesity-associated disruption of polarized lactate transporter MCT4 expression in human placenta.

Reprod Toxicol 2022 Jun 21. Epub 2022 Jun 21.

Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address:

Maternal obesity is associated with an increased risk of adverse pregnancy outcomes including stillbirth, and their etiology is thought to be related to placental and fetal hypoxia. In this study, we sought to investigate the levels of lactate in maternal and umbilical cord blood, a well characterized biomarker for hypoxia, and expression of plasma membrane lactate transporter MCT1 and MCT4 in the placental syncytiotrophoblast (STB), which are responsible for lactate uptake and extrusion, respectively, from pregnant women with a diagnosis of obesity following a Cesarean delivery at term. With use of approaches including immunofluorescence staining, Western blot, RT-qPCR and ELISA, our results revealed that in controls the expression of MCT1 was equally observed between basal (fetal-facing, BM) and microvillous (maternal-facing, MVM) membrane of the STB, whereas MCT4 was predominantly expressed in the MVM but barely detected in the BM. Read More

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Evaluation of placental oxygenation in fetal growth restriction using blood oxygen level-dependent magnetic resonance imaging.

Placenta 2022 Jun 18;126:40-45. Epub 2022 Jun 18.

Department of Obstetrics and Gynecology, Mie University Faculty Medicine, Mie, Japan.

Introduction: Abnormalities in placental function can lead to fetal growth restriction (FGR), but there is no consensus on their evaluation. Using blood oxygen level-dependent magnetic resonance imaging (BOLD MRI), we compared placental oxygenation between FGR cases and previously reported normal pregnancies.

Methods: Eight singleton pregnant women (>32 weeks of gestation) diagnosed with fetal growth failure during pregnancy were recruited. Read More

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Maternal Distress in Disclosing a Nonlethal Fetal Anomaly Diagnosis to Family and Friends.

MCN Am J Matern Child Nurs 2022 Jul-Aug 01;47(4):220-226

Purpose: To describe experiences of women disclosing a nonlethal fetal anomaly diagnosis to family and friends from initial prenatal diagnosis through postpartum.

Study Design And Methods: A descriptive, qualitative approach was used to explore women's perceptions of nonlethal fetal anomaly diagnosis in a high-risk obstetric clinic. In-depth interviews were conducted with 10 pregnant women, followed by postpartum interviews with 8 women. Read More

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Sex Hormone-Binding Globulin Level Enhances Prediction of Gestational Diabetes Mellitus in a Sub-Saharan African Population.

West Afr J Med 2022 Jun;39(6):580-587

Department of Chemical Pathology, Benue State University, Makurdi, Nigeria.

Background: The burden of Gestational Diabetes Mellitus (GDM) in the Sub-Saharan African region has been on the rise despite increased diagnosis and treatment. Current risk factor-based prediction approaches in the region lack strong predictive value, hence the need for effective early prediction and preventive interventions.

Aim: The aim of this study was to assess the diagnostic improvement in prediction of GDM by the addition of Sex Hormone-Binding Globulin (SHBG) assay to current approaches which assess early pregnancy maternal clinical risk factors in the study population. Read More

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Fear of childbirth and mental health among lesbian, bisexual, transgender and queer people: a cross-sectional study.

J Psychosom Obstet Gynaecol 2022 Jun 24:1-6. Epub 2022 Jun 24.

Department of Obstetrics and Gynecology in Norrköping, and Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.

Most studies of fear of childbirth (FOC) are conducted on heterosexual cisgender pregnant populations of birth-giving parents. Among lesbian and bisexual women, as well as transgender and queer people (LBTQ), minority stress can add an extra layer to FOC. Gender binary and cisnormative assumptions leave it to the patient to educate and navigate healthcare providers, which can increase mental health problems. Read More

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The influence of blood donation before pregnancy on neonatal birth weight.

PLoS One 2022 24;17(6):e0269367. Epub 2022 Jun 24.

Department of Blood Transfusion, Ningbo Medical Center Lihuili Hospital, Ningbo University, Ningbo, China.

Objective: To evaluate the effect of blood donation before pregnancy on neonatal birth weight.

Methods: A total of 14996 women with singleton pregnancies at full-term in Ningbo Medical Center Lihuili Hospital and Ningbo Women's and Children's Hospital from November 2019 to November 2020 were enrolled in this study. Detailed records of whole blood donation before pregnancy were obtained through Alipay software. Read More

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Association between Consumption of Geophagic Substance and Helminthic Infection among Pregnant Women, in Kisii County, Kenya.

West Afr J Med 2022 Jun;39(6):557-562

South Eastern Kenya University, P.O Box 170-90200, Kitui, Kenya.

Background: Soil-transmitted helminths constitutes the commonest of human parasitic infections worldwide. Millions of pregnant women who consume geophagic substances across the globe are predisposed to adverse maternal and prenatal outcomes including risk of helminthic infections. The association between type of geophagic substances consumed and helminthic infections among pregnant women in Kisii County is not documented. Read More

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The ability of a low value on an early GCT to identify women not needing repeat testing in the second trimester.

J Matern Fetal Neonatal Med 2022 Jun 24:1-7. Epub 2022 Jun 24.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Maimonides Medical Center, Brooklyn, NY, USA.

Objective: To evaluate the predictive value of a low early glucose challenge test (GCT) in ruling out a subsequent diagnosis of gestational diabetes in the second trimester.

Methods: This was a retrospective cohort study of women at a single clinic who had a normal early GCT between 2016 and 2020. Patients who did not have repeat screening in the late second trimester were excluded. Read More

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Estimates of Stillbirths, Neonatal Mortality, and Medically Vulnerable Live Births in Amhara, Ethiopia.

JAMA Netw Open 2022 Jun 1;5(6):e2218534. Epub 2022 Jun 1.

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.

Importance: Data on birth outcomes and early mortality are scarce, especially in settings with limited resources. Total births, both stillbirths and live births, are often not counted, yet such data are critical to allocate resources and target interventions to improve survival.

Objective: To estimate the prevalence of stillbirths, neonatal deaths, and medically vulnerable phenotypes, such as preterm births, small-for-gestational-age (SGA), large-for-gestational-age (LGA), and low-birth-weight (LBW) births, in a setting where these key indicators remain largely unknown. Read More

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Effects of an attachment-based intervention on autonomic regulation among opioid-exposed infants.

Dev Psychobiol 2022 Sep;64(6):e22286

Department of Psychological and Brain Sciences, University of Delaware, Newark, Delaware, USA.

Little is known about whether postnatal intervention enhances autonomic regulation among infants at risk for dysregulation due to prenatal opioid exposure. The present study evaluated the effects of modified Attachment Behavioral Catch-up (mABC) on autonomic regulation for opioid-exposed infants in a pilot randomized clinical trial. We hypothesized that, compared to a control intervention (modified Developmental Education for Families [mDEF]), mABC would be associated with higher resting respiratory sinus arrhythmia (RSA) and pre-ejection period (PEP) as well as greater reactivity to and recovery from a social stressor (Still-Face Paradigm). Read More

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September 2022

Socio-culturally adapted educational videos increase maternal and newborn health knowledge in pregnant women and female community health volunteers in Nepal's Khotang district.

Womens Health (Lond) 2022 Jan-Dec;18:17455057221104297

One Heart Worldwide, Lalitpur, Nepal.

Objectives: While Nepal has made significant improvements in maternal and newborn health overall, the lack of maternal and newborn health-related knowledge in the more rural parts of the country has led to significant disparities in terms of both maternal and newborn health service utilization and maternal and newborn health outcomes. This study aimed to assess whether viewing culturally adapted maternal and newborn health educational films had a positive impact on (1) the maternal and newborn health knowledge levels among pregnant women and (2) the postpartum hemorrhage-related knowledge levels among Female Community Health Volunteers in rural Nepal.

Methods: Four locations were selected for their remoteness and comparatively high number of pregnancies. Read More

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Improving access to maternal health services among rural hard-to-reach fishing communities in Uganda, the role of community health workers.

Womens Health (Lond) 2022 Jan-Dec;18:17455057221103993

Ghent University International Centre for Reproductive Health, Ghent, Belgium.

Objectives: To explore whether community health worker household-based maternal health visits improve antenatal care and skilled birth attendance among hard-to-reach fishing villages on Lake Victoria, Uganda.

Methods: This quasi-experimental 18-month prospective study involved 486 consenting women aged 15-49 years, who were pregnant or had a pregnancy outcome in the past 6 months, from 6 island fishing communities. The community health worker household-based intervention (community health workers' household visits to provide counseling, blood pressure measurement, anemia, and HIV testing) involved 243 women from three fishing communities. Read More

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Risk factors for low birth weight in El Jadida province, Morocco. Case-control study.

Rocz Panstw Zakl Hig 2022 ;73(2):209-214

Laboratory of Biotechnology, Biochemistry and Nutrition.Training and Research Unit on Nutrition & Food Sciences.Department of Biology.Faculty of Sciences.Chouaib Doukkali University. El Jadida, 24000. Morocco.

Background: Low birth weight (LBW) is considered to be one of the most important indicators of a newborn's chances of survival, and a major risk of medium- and long-term morbidity.

Objective: To identify risk factors associated with low birth weight newborns among pregnant women during childbirth in Moroccan hospital environment with a view to proposing avenues of intervention for its prevention.

Material And Methods: Data concerning the weight of newborns at birth, nutritional education, pregnancy monitoring and other risk factors, etc. Read More

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January 2022

Evaluation of the tolerability of monoclonal antibody therapy for pregnant patients with COVID-19.

J Obstet Gynaecol Res 2022 Jun 24. Epub 2022 Jun 24.

Department of Obstetrics and Gynecology, Mie University Faculty Medicine, Mie, Japan.

Aim: To evaluate the tolerability of casirivimab and imdevimab (CAS/IMB) therapy in pregnant women with COVID-19 in Japan and its impact on the neonate and process of delivery.

Methods: Eight cases of pregnancy complicated by COVID-19 and requiring hospitalization during the delta variant epidemic were included. Gestational age, initial symptoms, pregnancy complications and outcome, severity of illness, blood test findings at the time of treatment initiation and on days 3-5 after administration, body temperature at administration, and 8, 24, and 48 h post-administration, delivery outcome, and neonatal findings were recorded. Read More

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