40,288 results match your criteria pregnant patients


Current understanding of autophagy in intrahepatic cholestasis of pregnancy.

Placenta 2021 Sep 20;115:53-59. Epub 2021 Sep 20.

Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, 610041, China; Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Chengdu, 610041, China. Electronic address:

Intrahepatic cholestasis of pregnancy (ICP) is the most common liver disease during pregnancy. Manifested with pruritus and elevation in bile acids, the etiology of ICP is still poorly understood. Although ICP is considered relatively benign for the mother, increased rates of adverse fetal outcomes including sudden fetal demise are possible devastating outcomes associated with ICP. Read More

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September 2021

Cervical adenocarcinoma in situ during pregnancy and subsequent fertility-sparing therapy challenge.

Int J Gynaecol Obstet 2021 Sep 24. Epub 2021 Sep 24.

Department of Obstetrics and Gynecology, Infanta Sofía University Hospital, San Sebastián de los Reyes, Madrid, Spain.

Objective: Adenocarcinoma in situ (AIS) of the cervix is a premalignant lesion, precursor of invasive disease. It is less frequent than its squamous counterpart. During pregnancy, AIS is a scarcely described scenario, whose diagnosis barely differs from non-pregnant patients. Read More

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September 2021

Predictors of a successful vaginal delivery in women with type 1 diabetes: a retrospective analysis of 20 years.

Arch Gynecol Obstet 2021 Sep 24. Epub 2021 Sep 24.

Department of Obstetrics, University Hospital Jena, Am Klinikum 1, 07747, Jena, Germany.

Purpose: To evaluate the independent factors associated with the success of a trial of vaginal birth (TVB) in women with type 1 diabetes. Despite all therapeutic efforts and technological innovations, rates of caesarean sections (CS) in pregnant women with type 1 diabetes remain unchanged above 60%. Our aim was to point out influencing factors to improve the quality of antepartum counseling. Read More

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September 2021

Ultraviolet/Visible and Near-Infrared Dual Spectroscopic Method for Detection and Quantification of Low-Level Malaria Parasitemia in Whole Blood.

Anal Chem 2021 Sep 24. Epub 2021 Sep 24.

Centre for Biospectroscopy, School of Chemistry, Faculty of Science, Monash University, Wellington Road, Clayton, Victoria 3800, Australia.

The scourge of malaria infection continues to strike hardest against pregnant women and children in Africa and South East Asia. For global elimination, testing methods that are ultrasensitive to low-level ring-staged parasitemia are urgently required. In this study, we used a novel approach for diagnosis of malaria infection by combining both electronic ultraviolet-visible (UV/vis) spectroscopy and near infrared (NIR) spectroscopy to detect and quantify low-level (1-0. Read More

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September 2021

Predictive value of vascular endothelial growth factor and placenta growth factor for placenta accreta spectrum.

J Obstet Gynaecol 2021 Sep 24:1-6. Epub 2021 Sep 24.

Maternal-Fetal Medicine Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

This study aimed to assess the maternal features, Vascular Endothelial Growth Factor (VEGF) and Placenta Growth Factor (PLGF) in the Placenta Accreta Spectrum (PAS); then, to determine a predictive value of VEGF and PLGF in the PAS. This prospective case-control study was conducted on 90 pregnant women including 45 PAS, and 45 Normal Placenta (NP). Maternal age, gravidity, C/S, and serum levels of VEGF and PLGF were assessed between NP and PAS, and among NP and PAS sub-groups, including Placenta Accreta (PA), Placenta Increta (PI), and Placenta Percreta (PP). Read More

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September 2021

Fusarium keratitis as a growing problem - case report and literature review.

Ann Agric Environ Med 2021 Sep 23;28(3):409-413. Epub 2020 Nov 23.

Department of Vitreoretinal Surgery, Medical University, Lublin, Poland.

Introduction And Objectives: With the rising number of contact lens users, there has been observed an increasing number of patients admitted to ophthalmology wards with severe keratitis, including those of fungal etiology. One of the most devastating specimens is Fusarium spp. If not diagnosed and treated from the onset of the symptoms, it can lead to severe visual loss, or even blindness. Read More

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September 2021

The impact of family physicians in rural maternity care.

Birth 2021 Sep 23. Epub 2021 Sep 23.

Department of Environmental and Occupational Health, University of Colorado School of Public Health, Aurora, Colorado, USA.

Background: Reduced access to maternity care in rural areas of the United States presents a significant burden to pregnant persons and infants. The objective of this study was to estimate the impact of family physicians (FPs) on access to maternity care in rural United States hospitals, especially where other providers may not be available.

Methods: We administered a survey to 216 rural hospitals in 10 US states inquiring about the number of babies delivered from 2013 to 2017, the types of delivering physicians, and the maternity services offered. Read More

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September 2021

Predictors of periodontal and caries related perinatal oral healthcare, investigation of dentists' practices: a cross-sectional study.

PeerJ 2021 1;9:e12080. Epub 2021 Sep 1.

School of Dentistry, Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad, Pakistan.

Background: The objectives of the study were to assess the knowledge, attitude, and practice of dentists towards providing oral health care to pregnant women and to identify barriers and predictors of periodontal and caries related perinatal oral healthcare practices.

Methods: A cross-sectional analytical survey was conducted on dentists by using a random sampling technique, and a pre-validated questionnaire was delivered to 350 dentists from May 2018 to October 2018. Data were analyzed by utilizing SPSS software. Read More

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September 2021

Alpha-1 Antitrypsin Z Variant (AAT PI*Z) as a Risk Factor for Intrahepatic Cholestasis of Pregnancy.

Front Genet 2021 7;12:720465. Epub 2021 Sep 7.

Department of Genetics and Clinical Immunology, National Institute of Tuberculosis and Lung Diseases, Warsaw, Poland.

Intrahepatic cholestasis of pregnancy (ICP; prevalence 0.2-15.6%) is the most common pregnancy-related liver disorder. Read More

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September 2021

Vaginal microbiome as a tool for prediction of chorioamnionitis in preterm labor: a pilot study.

Sci Rep 2021 Sep 23;11(1):18971. Epub 2021 Sep 23.

Department of Obstetrics and Gynecology, Faculty of Medicine, Fukuoka University, 7-45-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan.

Intra-amniotic infection (IAI) is a major cause of preterm birth with a poor perinatal prognosis. We aimed to determine whether analyzing vaginal microbiota can evaluate the risk of chorioamnionitis (CAM) in preterm labor cases. Vaginal discharge samples were collected from 83 pregnant women admitted for preterm labor. Read More

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September 2021

Breast cancer and pregnancy: Why special considerations prior to treatment are needed in multidisciplinary care.

Biosci Trends 2021 Sep 23. Epub 2021 Sep 23.

Laboratory for Reproductive Immunology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.

Breast cancer diagnosed during pregnancy poses ethical and professional challenges. Clinical management of that condition should ensure the safety of both the mother and fetus. Clinical trials on breast cancer exclude pregnant women, so sufficient evidence with which to formulate guidelines for the management of these patients is lacking. Read More

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September 2021

Recent advances in pericarditis.

Eur J Intern Med 2021 Sep 20. Epub 2021 Sep 20.

University of Milano, Department of biomedical and clinical sciences "Luigi Sacco", Fatebenefratelli Hospital, Piazzale Principessa Clotilde 3, 20121, Milano, Italy. Electronic address:

Pericardial diseases are an heterogeneous group of entities, ranging from acute pericarditis to asymptomatic pericardial effusions. New advances in understanding the processes underlying them have been made. In 2020 a prospective study defined the reference intervals of the component of normal pericardial fluid, that was found to be rich in nucleated cells, proteins, albumin and LDH, at levels compatible with the inflammatory exudates of other biological fluids such as pleural or peritoneal fluid; Light's criteria should not be used to evaluate it. Read More

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September 2021

Validity of the ACTS intimate partner violence screen in antenatal care: a cross sectional study.

BMC Public Health 2021 Sep 24;21(1):1733. Epub 2021 Sep 24.

School of Clinical Sciences Auckland, Auckland University of Technology, Auckland, New Zealand.

Background: Intimate partner violence (IPV) is a major public health problem with harmful consequences. In Australia, there is no national standard screening tool and screening practice is variable across states. The objectives of this study were to assess in the antenatal healthcare setting: i) the validity of a new IPV brief screening tool and ii) women's preference for screening response format, screening frequency and comfort level. Read More

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September 2021

A comparative analysis and review of how national guidelines for chronic disease monitoring are made in low- and middle-income compared to high-income countries.

J Glob Health 2021 4;11:04055. Epub 2021 Sep 4.

Division of Epidemiology & Biostatistics, School of Public Health & Family Medicine, University of Cape Town, Cape Town, South Africa.

Background: Understanding how clinical practice guidelines and recommendations are adopted in high-income and low-income settings will help contextualise the value and validity of recommendations in different settings. We investigate how major guidelines and recommendations are developed for management and monitoring of post-diagnosis treatment for three important chronic diseases: HIV, hypertension and type 2 diabetes mellitus (T2DM).

Methods: Eligible guidelines were searched for using PubMed, Google, and health ministry websites for all three conditions. Read More

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September 2021

Trimester-based changes in urogenital symptoms and their impact on the quality of life in pregnant women: A preliminary report.

Curr Urol 2021 Sep 25;15(3):167-171. Epub 2021 May 25.

Division of Perinatalogy, Department of Obstetrics and Gynecology, Ankara, Turkey.

Background: This study is aimed to determine the trimester-based changes in urogenital symptoms and their impact on the quality of life in pregnant women.

Materials And Methods: Fifty-one pregnant women participated in this study. Self-reported symptom-based questionnaires, Urogenital Distress Inventory-Short Form (UDI-6), Incontinence Severity Index (ISI), and Incontinence Impact Questionnaire (IIQ-7) were administered to determine urogenital symptoms, incontinence severity, and the quality of life in all participants in the first, second, and third trimesters. Read More

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September 2021

Subjective Sleep Quality and Sleep Architecture in Patients With Migraine: A Meta-analysis.

Neurology 2021 Sep 22. Epub 2021 Sep 22.

Wolfson Centre for Age-Related Diseases, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom

Objectives: Sleep disturbance is often associated with migraine. However, there is a paucity of research investigating objective and subjective measures of sleep in migraine patients. This meta-analysis aims to determine whether there are differences in subjective sleep quality measured using the Pittsburgh Sleep Quality Index (PSQI), and objective sleep architecture measured using polysomnography between adult and pediatric patients, and healthy controls. Read More

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September 2021

Can Anakinra and corticosteroid treatment be an effective option in pregnant women with severe Covid-19?

Women Health 2021 Sep 22:1-8. Epub 2021 Sep 22.

Department of Internal Medicine, Division of Rheumatology, Ankara City Hospital, Yıldırım Beyazıt University, Ankara, Turkey.

Anakinra, which is an Interleukin-1 (IL-1) receptor antagonist with the advancing disease process, has started to be considered as an alternative treatment for Covid-19 patients with cytokine storms. We evaluated the effect of corticosteroids and IL-1 receptor blockage with anakinra on pregnant patients with Covid-19 at high risk for respiratory distress, ongoing fever, deterioration in their general condition and consequently maternal and fetal complications. Fourteen pregnant women who received anakinra (median dosage: 400 mg) and corticosteroid (methylprednisolone-median dosage: 80 mg) treatment were evaluated retrospectively. Read More

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September 2021

Development of standard definitions and grading for Maternal and Fetal Adverse Event Terminology.

Prenat Diagn 2021 Sep 22. Epub 2021 Sep 22.

Elizabeth Garrett Anderson Institute for Women's Health, University College London, 74 Huntley Street, London, WC1E 6AU, UK.

Objective: Adverse event (AE) monitoring is central to assessing therapeutic safety. The lack of a comprehensive framework to define and grade maternal and fetal AEs in pregnancy trials severely limits understanding risks in pregnant women. We created AE terminology to improve safety monitoring for developing pregnancy drugs, devices and interventions. Read More

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September 2021

Serum Neurofilament Light: a Potential Diagnostic and Prognostic Biomarker in Obstetric Posterior Reversible Encephalopathy Syndrome.

Mol Neurobiol 2021 Sep 22. Epub 2021 Sep 22.

Department of Obstetrics, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical Center for Critical Pregnant Women, No. 63, Duobao Road, Guangzhou, 510150, Guangdong, China.

Obstetric posterior reversible encephalopathy syndrome (PRES), caused by preeclampsia (PE) or eclampsia, is a clinical imaging syndrome and a critical maternal complication, with vasogenic edema in white matter as a typical imaging characteristic. Serum neurofilament light (NFL) is a marker of neuroaxonal injury. Therefore, we performed this study to explore the diagnostic and prognostic role of NFL in obstetric PRES. Read More

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September 2021

An Exploratory Study of the Role of Birth Stories in Shaping Expectations for Childbirth among Nulliparous Black Women: Everybody is Different (but I'm Scared).

J Midwifery Womens Health 2021 Sep 21. Epub 2021 Sep 21.

Central Carolina OB/BYN, Greensboro, North Carolina.

Introduction: Birth stories area source of information and vicarious experience for nulliparous women. Although health disparities research suggests that the childbirth experiences of Black women differ from those of white women, little research has been conducted about the nature of birth stories shared and their subsequent effect on expectations.

Methods: Pregnant nulliparous Black women were recruited from a women's health practice in the southeastern United States. Read More

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September 2021

Epidemiology of Sepsis-Associated Acute Kidney Injury in Beijing, China: A Descriptive Analysis.

Int J Gen Med 2021 14;14:5631-5649. Epub 2021 Sep 14.

Department of Intensive Care Unit, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People's Republic of China.

Background: Sepsis is the most common contributing factor towards development of acute kidney injury (AKI), which is strongly associated to poor prognostic outcomes. There are numerous epidemiological studies about sepsis-associated acute kidney injury (S-AKI), however current literature is limited with the majority of studies being conducted only in the intensive care unit (ICU) setting. The aim of this study was to assess the epidemiology of S-AKI in all hospitalized in-patients. Read More

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September 2021

[Analysis of the effect of modified cervical cerclage in the treatment of cervical insufficiency].

Zhonghua Fu Chan Ke Za Zhi 2021 Sep;56(9):609-615

Department of Obstetrics, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao 266035, China.

To discuss the surgical effect of modified cervical cerclage for the treatment of pregnant women with cervical insufficiency. The clinical data of 225 pregnant women who underwent modified cervical cerclage in Qilu Hospital (Qingdao) were selected for retrospective analysis from April 2014 to June 2020. Surgical success rate, full-term birth rate, preterm birth rate, prolonged pregnancy weeks and newborn birth weight were compared between singleton and twin pregnancies, preventive cerclage and emergency cerclage, surgery before and after 18 weeks, naturally and in vitro fertilization and embryo transfer (IVF-ET) conceived pregnant women respectively. Read More

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September 2021

Long-term infant outcomes after hyperbaric oxygen treatment for acute carbon monoxide poisoning during pregnancy.

Diving Hyperb Med 2021 Sep;51(3):248-255

Department of Undersea and Hyperbaric Medicine, Saglik Bilimleri Universitesi, Gulhane Egitim ve Arastirma Hastanesi, Ankara, Turkey.

Introduction: Carbon monoxide (CO) poisoning in pregnant women is linked to foetal mortality of 36-67%. This study assessed long-term fetal outcomes following hyperbaric oxygen treatment (HBOT) for acute CO poisoning in pregnant women. The effects of clinical severity parameters and pregnancy trimester were also analysed. Read More

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September 2021

Machine learning based early mortality prediction in the emergency department.

Int J Med Inform 2021 Sep 8;155:104570. Epub 2021 Sep 8.

School of Computer Science and Engineering, University of Electronic Science and Technology of China, Chengdu, China; Big Data Research Center, University of Electronic Science and Technology of China, Chengdu, China. Electronic address:

Background: It is a great challenge for emergency physicians to early detect the patient's deterioration and prevent unexpected death through a large amount of clinical data, which requires sufficient experience and keen insight.

Objective: To evaluate the performance of machine learning models in quantifying the severity of emergency department (ED) patients and identifying high-risk patients.

Methods: Using routinely-available demographics, vital signs and laboratory tests extracted from electronic health records (EHRs), a framework based on machine learning and feature engineering was proposed for mortality prediction. Read More

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September 2021

Maternal-Neonatal Transfer of SARS CoV-2 IgG Antibodies among Parturient Women Treated with BNT162b2 mRNA Vaccine during Pregnancy.

Am J Obstet Gynecol MFM 2021 Sep 18:100492. Epub 2021 Sep 18.

Department of Obstetrics and Gynecology, Sheba Medical Center, Tel Hashomer, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address:

Background: The exclusion of pregnant women from COVID-19 mRNA vaccine trials raised hesitancy regarding the benefit of vaccination of pregnant women, hence little is known about the vaccine's efficacy in this population.

Objective: To determine the maternal-neonatal transplacental transfer of SARS CoV-2 antibodies among vaccinated parturient women. A control group of COVID 19 recovered patients was included in order to compare IgG levels between vaccinated and recovered patients. Read More

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September 2021

Preterm birth among women with and without severe acute respiratory syndrome coronavirus 2 infection.

Acta Obstet Gynecol Scand 2021 Sep 21. Epub 2021 Sep 21.

Department of Obstetrics and Gynecology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, USA.

Introduction: Studies directly comparing preterm birth rates in women with and without severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are limited. Our objective was to determine whether preterm birth was affected by SARS-CoV-2 infection within a large integrated health system in New York with a universal testing protocol.

Material And Methods: This retrospective cohort study evaluated data from seven hospitals in New York City and Long Island between March 2020 and June 2021, incorporating both the first and second waves of the coronavirus disease 2019 (COVID-19) pandemic in the USA. Read More

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September 2021

Evaluation of the effect of gestational diabetes mellitus on fetal cardiac functions with myocardial performance index.

Minerva Obstet Gynecol 2021 Sep 21. Epub 2021 Sep 21.

Department of Pediatric Cardiology, Faculty of Medicine, Celal Bayar University, Manisa, Turkey.

Objective: We aimed to evaluate the fetal cardiac functions with myocardial performance index( MPI) in gestational diabetes mellitus (GDM).

Materials And Methods: In this study, 35 patients who were diagnosed with GDM and 35 pregnant without glucose intolerance and their babies were evaluated. Fetal echocardiographic, biometric measurements, umbilical artery pulsatility indices (UAPI) and ductus venosus pulsatility indices (DVPI) measurements were performed to evaluate fetal well-being between the groups. Read More

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September 2021

[Study of the specific toxic effects of the substance 1-[2-(2-benzoylphenoxy)ethyl]-6-methyluracil, the original non-nucleoside inhibitor of human immunodeficiency virus type 1 (Retroviridae; Orthoretrovirinae; Lentivirus: Human immunodeficiency virus 1) reverse transcriptase].

Vopr Virusol 2021 Sep 18;66(4):279-288. Epub 2021 Sep 18.

FSBEI HE «Lomonosov Moscow State University».

Introduction: Combination antiretroviral therapy is currently the main component of treatment for human immunodeficiency virus (HIV) infected patients. At the same time, the high mutational potential of the virus and the frequency of side effects of existing drugs dictate the need for the development and preclinical study of new, more effective and safer compounds.The aim of the study is to evaluate the specific types of toxicity of a new non-nucleoside inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RNA-dependent DNA revertase) (NNRTI) based on the substance 1-[2-(2-benzoylphenoxy)ethyl]-6-methyluracil, a benzophenone derivative. Read More

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September 2021

Effect of antithrombin Ⅲ among patients with disseminated intravascular coagulation in obstetrics: a nationwide observational study in Japan.

BJOG 2021 Sep 21. Epub 2021 Sep 21.

Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.

Objective: Pregnant women may develop disseminated intravascular coagulation (DIC), possibly resulting in massive maternal haemorrhage and perinatal death. The Japan guideline recommends use of antithrombin Ⅲ (ATⅢ) for DIC in obstetrics; however, its effect remains uncertain. The present study aimed to investigate the effect of ATⅢ for DIC in obstetrics, using a national inpatient database in Japan. Read More

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September 2021

The Effect of Using In Vitro Fertilization (IVF) on Increasing the Prevalence of Craniosynostosis.

J Craniofac Surg 2021 Sep 20. Epub 2021 Sep 20.

Department of Plastic and Craniofacial Surgery, Medical College of Shahid Beheshti University of Medical Science (SBUM), 15 Khordad Hospital Department of Neurosurgery, School of Medicine, Mofid Children's Hospital, Shahid Beheshti University of Medical Sciences Tehran University of Medical Sciences, Pharmacology Department, Tehran, Iran Brain Imaging Center, Douglas Hospital Mental Health University Institute, Montreal, Quebec, Canada Tehran University of Medical Sciences (TUMS), Tehran, Iran.

Background: Craniosynostosis, a malformation caused by premature closure of one or more cranial sutures, is a rare congenital disability usually of unknown cause; however, it is often associated with assisted reproductive technology. Given the increasing prevalence of craniosynostosis and the use of the in vitro fertilization (IVF) method, the authors evaluated the association between IVF and the prevalence of craniosynostosis.

Methods: This retrospective study reviewed records of patients with nonsyndromic craniosynostosis who underwent surgery in Mofid Hospital, a tertiary children's hospital affiliated to Shahid Beheshti University of Medical Sciences, between 2010 and 2019. Read More

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September 2021