1,037,662 results match your criteria pregnancy


Air pollution and preterm birth: A time-stratified case-crossover study in the San Joaquin Valley of California.

Paediatr Perinat Epidemiol 2021 Dec 6. Epub 2021 Dec 6.

Department of Public Health, School of Social Sciences, Humanities and Arts, University of California, Merced, California, USA.

Background: Air pollution is linked to preterm birth (PTB), but existing studies are primarily focused on chronic exposures, conducted in areas with moderate pollution, and/or subject to confounding.

Objectives: We investigated short-term associations between two pollutants [particulate matter <2.5 microns (PM ) and ozone] and PTB, and estimated excess PTB cases potentially attributed to these pollutants. Read More

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December 2021

Review article: Management of hyperemesis gravidarum and nausea and vomiting in pregnancy.

Emerg Med Australas 2021 Dec 6. Epub 2021 Dec 6.

Royal Darwin Hospital, Darwin, Northern Territory, Australia.

Nausea and vomiting in pregnancy (NVP) are common in early pregnancy but there is a wide spectrum of severity in terms of the duration and acuity of symptoms throughout gestation. Adverse maternal and fetal outcomes have been seen in women who experience severe symptoms, also known as hyperemesis gravidarum (HG). Evidence-based, assessment and management can reduce symptom severity, avoid physical and psychological deterioration and minimise the impact on quality of life and function. Read More

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December 2021

Can Prenatal and Postnatal Cell Phone Exposure Increase Adverse Maternal, Infant and Child Outcomes?

Rev Bras Ginecol Obstet 2021 Nov 6;43(11):870-877. Epub 2021 Dec 6.

Non-communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran.

Objective:  To determine the association between maternal mobile phone use and adverse outcomes in infants, children, and mothers.

Method:  In March 202, we conducted a search on the MEDLINE, Embase, and Scopus databases. Data extraction and an assessment of the quality of the studies were performed by two authors. Read More

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November 2021

Dyspnea and COVID-19: A Review of Confounding Diagnoses during the Postpartum Period.

Rev Bras Ginecol Obstet 2021 Nov 6;43(11):862-869. Epub 2021 Dec 6.

Department of Gynecology and Obstetrics, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.

The puerperium is a complex period that begins with placental delivery and lasts for 6 weeks, during which readaptation of the female organism and redistribution of blood volume occur. This period is conducive to the occurrence of thromboembolic events. In the context of the SARS-CoV-2 pandemic, the virus responsible for COVID-19, the attention of the scientific community and health professionals has been focused on obtaining insights on different aspects of this disease, including etiology, transmission, diagnosis, and treatment. Read More

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November 2021

Perinatal Outcomes and Factors Associated with Ethnic Group in cases of Preterm Birth: the Multicenter Study on Preterm Birth in Brazil.

Rev Bras Ginecol Obstet 2021 Nov 6;43(11):811-819. Epub 2021 Dec 6.

Department of Obstetrics and Gynecology, Faculdade de Ciências Médicas, Universidade Estaudual de Campinas, Campinas, SP, Brazil.

Objective:  To investigate the characteristics of women who had preterm birth (PTB) and related outcomes according to ethnicity.

Methods:  A secondary analysis of a multicenter cross-sectional study conducted in Brazil. Women who had PTB were classified by self-report as white and non-white. Read More

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November 2021

Association Between PON1 (L55M and Q192R) Genetic Polymorphism and Recurrent Pregnancy Loss in North Indian Women Exposed to Pesticides.

Rev Bras Ginecol Obstet 2021 Nov 6;43(11):805-810. Epub 2021 Dec 6.

Department of Obstetrics and Gynecology, King George's Medical University, Lucknow, Uttar Pradesh, India.

Objective:  The aim of the present study was to examine the relation between the PON1 polymorphisms and recurrent pregnancy loss (RPL).

Methods:  In a cross-sectional study, blood samples were collected from 100 females. DNA was extracted and PON1 genotypes were determined by polymerase chain reaction (PCR) amplification. Read More

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November 2021

Maternal Serum and Cord Blood Leptin Concentrations at Delivery in Normal Pregnancies and in Pregnancies Complicated by Intrauterine Growth Restriction.

Obes Facts 2021 Dec 6:1-8. Epub 2021 Dec 6.

Department of Obstetrics and Gynecology Didactics, Medical University of Warsaw, Warsaw, Poland.

Introduction: Leptin is a polypeptide hormone, and in pregnancy, it is secreted by the placenta and maternal and fetal adipose tissues. Normal leptin production is a factor responsible for uncomplicated gestation, embryo development, and fetal growth. The study compared maternal serum and cord blood leptin concentrations at delivery in normal pregnancies and in pregnancies complicated by intrauterine growth restriction (IUGR). Read More

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December 2021

Preconception health service provision among women with and without substance use disorders.

Drug Alcohol Depend 2021 Nov 26;230:109194. Epub 2021 Nov 26.

Department of Family and Community Medicine, Saint Louis University School of Medicine, SLUCare Academic Pavilion, 1008S. Spring Ave. 3rd Floor, Saint Louis, MO 63110, United States. Electronic address:

Background: Drug and alcohol use during pregnancy is associated with significant adverse birth outcomes and maternal morbidity. Addressing health and risky behaviors before pregnancy, in the preconception period, can improve both maternal and infant outcomes. However, the prevalence of preconception service delivery among women with substance use disorders (SUD) is unknown. Read More

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November 2021

The Charité external cephalic version for leading twin breech without regional anesthesia and tocolysis. A prospective study on feasibility, sonographic assessment and outcomes.

Eur J Obstet Gynecol Reprod Biol 2021 Nov 24;268:62-67. Epub 2021 Nov 24.

Dept. of Obstetrics, Charité Hospital, Humboldt University, Berlin, Germany.

Objectives: To assess the feasibility of external cephalic version (ECV) for the leading twin (twin A) in breech presentation in dichorionic and diamniotic twin pregnancies without the use of regional anesthetics and tocolysis and to characterize the sonographic parameters, maternal and neonatal outcomes.

Study Design: Prospective study performed in the Charité University Hospital outpatient obstetric department in Berlin, Germany. A total of 23 women from the 35th completed week of pregnancy with confirmed dichorionic-diamniotic twin pregnancy were recruited. Read More

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November 2021

Non-esterified fatty acids as biomarkers of diet and glucose homeostasis in pregnancy: The impact of fatty acid reporting methods: NEFA reporting methods affect dietary and cardiometabolic endpoints.

Prostaglandins Leukot Essent Fatty Acids 2021 Nov 23;176:102378. Epub 2021 Nov 23.

Department of Chemistry and Chemical Biology, McMaster University, Hamilton, ON, Canada.

Background: Sparse data exists on the utility of individual serum non-esterified fatty acids (NEFAs) as clinical and dietary biomarkers and how reporting methods could affect these associations. We investigated the associations of 19 serum NEFAs expressed as µM or mol%, with self-reported dietary intake data, and cardiometabolic health indicators in pregnant women.

Methods: In this cross-sectional study, 273 pregnant women in their second trimester each completed a semi-quantitative food-frequency questionnaire and provided fasting serum samples. Read More

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November 2021

Fatty acid compositions of immature and mature testis are differently responsive to dietary docosahexasenoic acid during development in rats exposed to prenatal ethanol.

Prostaglandins Leukot Essent Fatty Acids 2021 Nov 20;176:102379. Epub 2021 Nov 20.

Department of Food and Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, Canada; Division of Neurodegenerative Disorders, Winnipeg, Manitoba, Canada; Canadian Centre for Agri-Food Research in Health and Medicine, St. Boniface Hospital Albrechtsen Research Centre, Winnipeg, Manitoba, Canada. Electronic address:

Background: Ethanol (EtOH) exposure impairs, but docosahexaenoic acid (DHA) supports testis functions. This study investigated whether dietary DHA and prenatal EtOH exposure affected fatty acid profiles equally in immature and mature testis during developmental stages.

Methods: Female rats were exposed to ± EtOH (3g/kg BW, twice a day via gavage) throughout pregnancy, while consuming a diet supplemented ± DHA (1. Read More

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November 2021

Maternal cradling bias: A marker of the nature of the mother-infant relationship.

Authors:
Jacques Vauclair

Infant Behav Dev 2021 Dec 3;66:101680. Epub 2021 Dec 3.

Center for Research on the Psychology of Cognition, Language and Emotion (PsyCLE), Aix-Marseille University, Aix-en-Provence, France. Electronic address:

The tendency of mothers to cradle their infant on their left side was first demonstrated by Salk back in 1960, but has been the subject of renewed interest in recent years. In this paper, I examine the different aspects of this tendency, making a short detour to explore this behavioral bias in other mammals and in nonhuman primates. The left cradling bias has been investigated not only in mothers, but also in fathers, children and students, as well as in different cultures. Read More

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December 2021

Pregnancy, Preeclampsia and Maternal Aging: From Epidemiology to Functional Genomics.

Ageing Res Rev 2021 Dec 3:101535. Epub 2021 Dec 3.

Department of Obstetrics and Gynecology, Columbia University Irving Medical Center, New York, NY, USA; Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY, USA. Electronic address:

Women live longer than men but experience greater disability and a longer period of illness as they age. Despite clear sex differences in aging, the impact of pregnancy and its complications, such as preeclampsia, on aging is an underexplored area of geroscience. This review summarizes our current knowledge about the complex links between pregnancy and age-related diseases, including evidence from epidemiology, clinical research, and genetics. Read More

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December 2021

Preconception care and severe maternal morbidity in the United States.

Am J Obstet Gynecol MFM 2021 Dec 3:100549. Epub 2021 Dec 3.

Department of Family Medicine, University of Chicago, Chicago, IL.

Background: In the United States, approximately 52,000 women per year (1.46% of births) experience severe maternal morbidity, defined as a complication that causes significant maternal harm or risk of death. Severe maternal morbidity disproportionately affects women from racial or ethnic minorities, people with chronic diseases, and those with Medicaid or no insurance. Read More

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December 2021

Robotic Transvaginal Natural Orifice Transluminal Endoscopic Surgery for resection of Parametrial and Bowel Deeply Infiltrated Endometriosis.

J Minim Invasive Gynecol 2021 Dec 3. Epub 2021 Dec 3.

Division of Urogynecology, Shanghai First Maternity and Infant Hospital, Tongji University, Shanghai, China.

Objective: To demonstrate stepwise techniques for the successful utilization of the Robotic-assisted transvaginal Natural Orifice Transluminal Endoscopy Surgery (NOTES) technique for safely surgical managing deeply infiltrated endometriosis (DIE) Design: Stepwise demonstration with narrated video footage.

Setting: An academic tertiary care hospital.

Interventions: A 38-year-old G3P3, NSVDx1 and CSx1 for twin pregnancy with worsening chronic pelvic pain. Read More

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December 2021

Integrating in vitro chemical transplacental passage into a generic PBK model: A QIVIVE approach.

Toxicology 2021 Dec 3:153060. Epub 2021 Dec 3.

Centre for Nutrition, Prevention and Health Services, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.

With the increasing application of cell culture models as primary tools for predicting chemical safety, the quantitative extrapolation of the effective dose from in vitro to in vivo (QIVIVE) is of increasing importance. For developmental toxicity this requires the scaling in vitro observed dose-response characteristics to in vivo fetal exposure, while integrating maternal in vivo kinetics during pregnancy, in particular transplacental transfer. Here the transfer of substances across the placental barrier, has been studied using the in vitro BeWo cell assay and six embryotoxic compounds of different kinetic complexity. Read More

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December 2021

Racial and ethnic disparities in pregnancy complications and the protective role of greenspace: A retrospective birth cohort study.

Sci Total Environ 2021 Dec 3:152145. Epub 2021 Dec 3.

Department of Geography and Planning, Appalachian State University, P.O. Box 32066, Boone, NC 28608, USA. Electronic address:

Greenspace may positively impact pregnancy health for racially and economically minoritized women; few studies have examined local availability and accessibility of green/park space in reducing maternal morbidity. The objective of this retrospective birth cohort study was to examine the association between residential exposure to greenspace and adverse pregnancy health outcomes in a Southern US state characterized by high poverty and racial disparities in maternal health (2013-2017). National data from the Protected Area database - United States (PAD-US) and ParkServe estimated three publicly available and accessible residential greenspace measures-a more direct proxy than using remotely-sensed greenness indicators (e. Read More

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December 2021

Antioxidants in male infertility.

Authors:
Scott D Lundy

Urology 2021 Dec 3. Epub 2021 Dec 3.

Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA. Electronic address:

Objective: To study the effect of three antioxidants viz. selenium, carnitine and coenzyme Q10, alone or in combination, on both semen parameters and pregnancy rates in couples with male factor infertility.

Methods: Using PRISMA guidelines, a systematic search was performed of the PubMed®, Scopus®, EMBASE®, and Web of Science® databases for randomized studies comparing selenium, carnitine or coenzyme Q10 with placebo in the treatment of male infertility and reporting semen and pregnancy outcomes. Read More

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December 2021

Maternal serum-derived exosomal lactoferrin as a marker in detecting and predicting ventricular septal defect in fetuses.

Exp Biol Med (Maywood) 2021 Dec 6:15353702211060517. Epub 2021 Dec 6.

Department of Reproductive Endocrinology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.

Among different types of congenital heart diseases, ventricular septal defect is the most frequently diagnosed type and is frequently missed in early prenatal screening programs. Herein, we explored the role of maternal serum-derived exosomes in detecting and predicting ventricular septal defect in fetuses in the early stage of pregnancy. A total of 104 pregnant women consisting of 52 ventricular septal defect cases and 52 healthy controls were recruited. Read More

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December 2021

Histopathological profile of women who had previously failed IVF and the association to the outcome in the subsequent IVF cycle.

Obstet Gynecol Sci 2021 Dec 6. Epub 2021 Dec 6.

Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, McGill University, Montreal, Canada.

Objective: To evaluate the endometrial histopathological profile of patients undergoing curettage and the association of the histopathological profile with the pregnancy outcome during the subsequent IVF cycle.

Methods: In this retrospective cohort study, a total of 248 women with at least one failed attempt of IVF and who underwent curettage and a subsequent IVF were included. Demographic data, endometrial histopathological records, stimulation information, and pregnancy outcomes were collected and analyzed. Read More

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December 2021

Echogenicities in the fetal gallbladder: Prevalence, sonographic findings, and postnatal outcomes.

J Clin Ultrasound 2021 Oct 20. Epub 2021 Oct 20.

Specialist, Department of Obstetric and Gynecology, Şehit Prof. Dr. Ilhan Varank Training and Research Hospital, Istanbul, Turkey.

Purpose: To investigate the prevalence of echogenicity in the fetal gallbladder (EFG) and to present prenatal sonographic findings and their postnatal outcomes.

Materials And Methods: We performed a retrospective study within 17420 pregnant women during a 66-month period. Fetuses with an incidental finding of EFG in their 2nd or 3rd trimester of pregnancy were followed until birth per two weeks with sonographic examinations. Read More

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October 2021

Rebound of platelet count in a patient with type 2 calreticulin-mutant essential thrombocythemia in the postpartum period: A case report.

Medicine (Baltimore) 2021 Nov;100(44):e27725

National Center for Cancer Care and Research, Department of Oncology, Hematology and BMT Section, Hamad Medical Corporation, Doha, Qatar.

Introduction: Essential thrombocythemia (ET) is an uncommon myeloproliferative neoplasm. It is more common in females; 20% of them are below 40 years old. The optimal management of ET during pregnancy and postpartum periods is still not well established. Read More

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November 2021

Predictors of oral pre-exposure prophylaxis (PrEP) uptake among individuals in a HIV vaccine preparedness cohort in Masaka, Uganda.

Medicine (Baltimore) 2021 Nov;100(44):e27719

Department of HIV and Emerging Infections, Medical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda.

Abstract: Oral pre-exposure prophylaxis (PrEP) significantly reduces human immunodeficiency virus (HIV) acquisition risk. However, data on predictors of PrEP uptake in sub-Saharan Africa are limited. We assessed predictors of PrEP uptake among HIV-uninfected high risk individuals enrolled in a HIV vaccine preparedness study in Masaka, Uganda. Read More

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November 2021

Survey of physician knowledge of congenital cytomegalovirus infection and clinical practices in Japan: A web-based survey.

Medicine (Baltimore) 2021 Nov;100(44):e27589

Department of Pediatrics and Child Health, Nihon University School of Medicine, 30-1 Oyaguchikamicho, Itabashi-ku, Tokyo, Japan.

Abstract: Congenital cytomegalovirus infection (cCMVi) can cause serious and long-term effects in newborns. Without available vaccines or antiviral prophylaxis, prevention strategies for cCMVi and cytomegalovirus disease during pregnancy are limited to hygiene and behavioral interventions to prevent transmission. The objective of this study was to assess cCMVi-related awareness, knowledge, and physicians' actual and preferred clinical practices in Japan. Read More

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November 2021

Maternal health indicators in Brazil: A time series study.

Medicine (Baltimore) 2021 Nov;100(44):e27118

Nurse. Doctor of Health Sciences. Department of Nurse. Federal University of Rio Grande do Norte, Natal, Brazil.

Abstract: In addition to the maternal death indicator, Stork Network proposes the number of prenatal consultations, the gestational age of onset of prenatal care and the number of children breastfeeding.The study aims to analyze maternal health indicators representative of the actions proposed by Stork Network in Brazil, after its implementation. Therefore, this is an ecological study of maternal health indicators in Brazil from 2012 to 2017. Read More

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November 2021

Comparison of intrapartum glycemic management strategies in pregnant women with type 1 diabetes mellitus.

J Matern Fetal Neonatal Med 2021 Dec 6:1-5. Epub 2021 Dec 6.

Department of Obstetrics and Gynecology, University of Massachusetts Memorial Medical Center, University of Massachusetts Medical School, Worcester, MA, USA.

Background: Achieving intrapartum maternal euglycemia in women with type 1 diabetes mellitus (T1DM) is critical to reducing the risk of neonatal hypoglycemia.

Objective: This study sought to compare the maternal and neonatal outcomes among women with T1DM by different intrapartum glycemic control strategies of continuation of subcutaneous insulin pumps versus intravenous insulin infusion.

Methods: A retrospective cohort study was performed to identify all women with type 1 diabetes mellitus in pregnancy between 1 October 2017 and 1 August 2020 at our tertiary medical center. Read More

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December 2021

Reasons for unfulfilled breeding and transfer recommendations in zoos and aquariums.

Zoo Biol 2021 Dec 6. Epub 2021 Dec 6.

Alexander Center for Applied Population Biology, Lincoln Park Zoo, Chicago, Illinois, USA.

One of the primary tools for cooperatively managing animal populations within the Association of Zoos and Aquariums is through Breeding and Transfer Plan (BTP) recommendations. These recommendations consider population demographics, genetics, husbandry, and institutional needs and aim to improve population viability and long-term sustainability. However, fulfilling (i. Read More

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December 2021

Differentiation and Expansion of Human Extra-Embryonic Endoderm Cell Lines from Naïve Pluripotent Stem Cells.

Methods Mol Biol 2022 ;2416:105-116

Novo Nordisk Foundation Center for Stem Cell Biology, University of Copenhagen, Copenhagen, Denmark.

In human, endoderm is induced in two waves, with the first being the extra-embryonic primitive endoderm (PrE), otherwise known as hypoblast, induced during blastocyst development, and the second being gastrulation-stage definitive endoderm (DE). The PrE gives rise to the primary and secondary yolk sac, and has supportive functions during pregnancy for nutrient provision, with descendants of this extra-embryonic lineage also playing a role in embryonic patterning. As in DE specification, we recently found that PrE could be induced in vitro by Wnt and Nodal-related signaling, but that the critical difference was in the pluripotent starting point for differentiation. Read More

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January 2022

Generating Trophoblast Stem Cells from Human Naïve Pluripotent Stem Cells.

Methods Mol Biol 2022 ;2416:91-104

Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA.

The placenta is a transient organ that mediates the exchange of nutrients, gases, and waste products between the mother and the developing fetus and is indispensable for a healthy pregnancy. Epithelial cells in the placenta, which are termed trophoblasts, originate from the trophectoderm (TE) compartment of the blastocyst. The human trophoblast lineage consists of several distinct cell types, including the self-renewing and bipotent cytotrophoblast and the terminally differentiated extravillous trophoblast and syncytiotrophoblast. Read More

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January 2022