183,592 results match your criteria pregnancies birth


The impact of indomethacin on the number of oocytes retrieved and IVF outcomes in patients with poor ovarian response.

Eur J Obstet Gynecol Reprod Biol 2021 Jul 24;264:266-270. Epub 2021 Jul 24.

Center for Assisted Reproduction, Department of Obstetrics and Gynecology, Ankara University Faculty of Medicine, Ankara, Turkey.

Objective: The aim of this retrospective case-control study was to analyze the effect of administering indomethacin after triggering final oocyte maturation in patients with poor ovarian response (POR) on the cycle cancellation rate due to premature ovulation (PO), the number of oocytes retrieved and the clinical outcomes of IVF cycles.

Study Design: A total of 214 patients with POR, diagnosed according to the Bologna criteria, who underwent fresh IVF cycle via flexible gonadotrophin-releasing hormone antagonist (GnRH-ant) protocol were enrolled in the study. The control group consisted of 100 patients, whereas the indomethacin group included 114 patients who received 100 mg rectal indomethacin administered twice within the same day (twelve hours apart) -starting at twelve hours after triggering. Read More

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Congenital anomalies associated with ambient temperature variability during fetal organogenesis period of pregnancy: Evidence from 4.78 million births.

Sci Total Environ 2021 Jul 28;798:149305. Epub 2021 Jul 28.

School of Health Management, Southern Medical University, Guangzhou 510515, Guangdong Province, China. Electronic address:

Backgrounds: Evidence for the effects of temperature variability on risk of congenital anomalies is lacking. We aimed to examine the association of temperature variability during fetal organogenesis period (weeks 3-8 post-conception) with major congenital anomalies.

Methods: A retrospective cohort study comprising 4,787,356 singleton live-births and stillbirths in China was performed. Read More

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Labour induction massage: A thematic content analysis of Australian massage therapists' website pages.

Complement Ther Clin Pract 2021 Jul 29;45:101461. Epub 2021 Jul 29.

School of Health Sciences, Western Sydney University, Australia; IIMPACT in Health, University of South Australia, Australia.

Background And Purpose: There is limited evidence on the efficacy and safety of induction massage; however, there are some massage therapists in Australia who offer induction massage. The aim of this paper is to determine the information being provided to consumers on websites pages of Australian massage therapists who provide 'induction massage'.

Materials And Methods: A qualitative summative content analysis methodology employing both manifest and latent content analysis was used to examine website pages of Australian massage therapists offering 'induction massage'. Read More

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Urinary glyphosate concentration in pregnant women in relation to length of gestation.

Environ Res 2021 Jul 30:111811. Epub 2021 Jul 30.

Department of Environmental Medicine and Public Heath, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address:

Human exposure to glyphosate-based herbicides (GBH) is increasing rapidly worldwide. Most existing studies on health effects of glyphosate have focused on occupational settings and cancer outcomes and few have examined this common exposure in relation to the health of pregnant women and newborns in the general population. We investigated associations between prenatal glyphosate exposure and length of gestation in The Infant Development and the Environment Study (TIDES), a multi-center US pregnancy cohort. Read More

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Prevalence of short interpregnancy interval and its associated factors among pregnant women in Debre Berhan town, Ethiopia.

PLoS One 2021 2;16(8):e0255613. Epub 2021 Aug 2.

School of Medicine, College of Health Sciences and Medicine, Wolaita Sodo University, Wolaita Sodo, Ethiopia.

Background: Short inter-pregnancy interval is an interval of <24 months between the dates of birth of the preceding child and the conception date of the current pregnancy. Despite its direct effects on the perinatal and maternal outcomes, there is a paucity of evidence on its prevalence and determinant factors, particularly in Ethiopia. Therefore, this study assessed the prevalence and associated factors of short inter-pregnancy interval among pregnant women in Debre Berhan town, Northern Ethiopia. Read More

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Association of Expanded Prenatal Care Coverage for Immigrant Women With Postpartum Contraception and Short Interpregnancy Interval Births.

JAMA Netw Open 2021 Aug 2;4(8):e2118912. Epub 2021 Aug 2.

Center for Health Systems Effectiveness, Oregon Health & Science University, Portland.

Importance: Access to prenatal and postpartum care is restricted among women with low income who are recent or undocumented immigrants enrolled in Emergency Medicaid.

Objective: To examine the association of extending prenatal care coverage to Emergency Medicaid enrollees with postpartum contraception and short interpregnancy interval births.

Design, Setting, And Participants: This cohort study used a difference-in-differences design to compare the staggered rollout of prenatal care in Oregon with South Carolina, a state that does not cover prenatal or postpartum care. Read More

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Choline and docosahexaenoic acid during the first 1000 days and children's health and development in low- and middle-income countries.

Nutr Rev 2021 Aug 2. Epub 2021 Aug 2.

M.G. Bragg, E.L. Prado, and C.P. Stewart are with the Institute for Global Nutrition, University of California Davis, Davis, California, United States.

Choline and DHA are nutrients that, when provided during the first 1000 days from conception to age 2 years, may have beneficial effects on child neurodevelopment as well as related health factors, including birth outcomes and child growth, morbidity, and inflammation. Because these nutrients are found mainly in animal-source foods, they may be lacking in the diets of pregnant and lactating women and young children in low- and middle-income countries, potentially putting children at risk for suboptimal development and health. Prior reviews of these nutrients have mainly focused on studies from high-income countries. Read More

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Multivariate analysis of oocyte donor and recipient factors affecting cumulative live birth rate in oocyte donor IVF (OD-IVF) cycles.

JBRA Assist Reprod 2021 Aug 2;0(0). Epub 2021 Aug 2.

Department of Obstetrics & Gynaecology, All India Institute of Medical Sciences, New Delhi, India.

Objective: To study donor and recipient factors affecting cumulative live birth rate (CLBR) in oocyte donor IVF (OD- IVF) cycles.

Methods: The present retrospective study was conducted at the ART center of a tertiary care referral hospital after ethical approval, and included all OD-IVF cycles done between January 2014 - October 2019. Donor parameters included age, body mass index (BMI), ovarian reserve markers, serum estradiol (E2) on trigger day, and number of total/grade 1 oocytes; recipient parameters included age and BMI. Read More

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Characteristics, maternal and neonatal outcomes of acute kidney injury in preeclampsia: A prospective, single-center study.

Clin Nephrol 2021 Aug 2. Epub 2021 Aug 2.

Background: Preeclampsia is an important cause of pregnancy-related acute kidney injury (AKI). The objective of our study was to determine the incidence, characteristics, and maternal and neonatal outcomes of AKI in pregnant women with preeclampsia.

Materials And Methods: A prospective, observational, single-center study from January 2019 to January 2020. Read More

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Biological and clinical effects of a resveratrol-based multivitamin supplement on intracytoplasmic sperm injection cycles: a single-center, randomized controlled trial.

J Matern Fetal Neonatal Med 2021 Aug 1:1-9. Epub 2021 Aug 1.

Centre of Assisted Reproductive Technologies, S. Maria della Misericordia Hospital, Perugia, Italy.

Background: Resveratrol display's positive effects on follicle growth and development in preclinical studies while there is scantly information from clinical trials. The aim of this study was to evaluate the biological and clinical impact of a resveratrol-based multivitamin supplement on intracytoplasmatic sperm injection (ICSI) cycles.

Methods: A randomized, single-center controlled trial conducted at the University Center of Assisted Reproductive Technologies involving 101 women infertile women undergoing ICSI cycles was conducted. Read More

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Novel epigenetic link between gestational diabetes mellitus and macrosomia.

Epigenomics 2021 Aug 2. Epub 2021 Aug 2.

Center for Global Oncology, Institute for Global Health, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.

Examine maternal gestational diabetes mellitus (GDM), macrosomia and DNA methylation in candidate genes , , , , , ,  and . 1145 Children (572 GDM cases and 573 controls) from The Tianjin GDM study, including 177 with macrosomia, had blood DNA collection at median age 5.9 (range: 3. Read More

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Toxic elements in follicular fluid adversely influence the likelihood of pregnancy and live birth in women undergoing IVF.

Hum Reprod Open 2021 29;2021(3):hoab023. Epub 2021 Jul 29.

Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California at San Francisco, San Francisco, CA, USA.

Study Question: Are follicular fluid (FF), arsenic (As), mercury (Hg), cadmium (Cd) and lead (Pb) concentrations associated with IVF outcomes among women undergoing IVF?

Summary Answer: There was a non-linear association between higher FF Hg concentration and a lower likelihood of biochemical pregnancy and live birth. Higher FF Pb concentration was also associated with a lower probability of live birth.

What Is Known Already: Previous research suggests that toxic elements may affect fertility among couples conceiving with and without assistance. Read More

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Cardiac Myosarcoma in a Newborn Infant-A Case Report and Literature Review.

Front Cardiovasc Med 2021 14;8:675202. Epub 2021 Jul 14.

Faculty of Medicine, Medical University of Sofia, Sofia, Bulgaria.

Malignant cardiac neoplasms are extremely rare in neonates. Prenatal diagnosis is often not available. Initial symptoms can mimic non-cardiac diseases. Read More

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Maternal and Perinatal Outcomes of Pregnancy in Women With Autoimmune Disorder.

Cureus 2021 Jun 29;13(6):e16024. Epub 2021 Jun 29.

Obstetrics and Gynaecology, All India Institute of Medical Sciences, New Delhi, IND.

Objective Pregnancy with an autoimmune disorder is faced with several risks for mother and fetus. The aim of the present study is to analyze the course and outcome of pregnancy in women with autoimmune disorders (AIDs). Methods A retrospective cohort study was conducted at a tertiary care teaching hospital. Read More

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The role of vitamin D in perinatology. An up-to-date review.

Arch Med Sci 2021 30;17(4):992-1005. Epub 2019 Jan 30.

First Department of Obstetrics and Gynecology, Center of Postgraduate Medical Education, Warsaw, Poland.

The role of vitamin D in perinatology is a subject of major interest in current medicine. There is growing evidence about the role of maternal vitamin D levels in pregnancy outcomes. The aim of this review is to summarize the current literature about the role of vitamin D in perinatology. Read More

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January 2019

False-Positive Maternal Serum Screens in the Second Trimester as Markers of Placentally Mediated Complications Later in Pregnancy: A Systematic Review and Meta-Analysis.

Dis Markers 2021 4;2021:5566234. Epub 2021 Jun 4.

Department of Epidemiology and Population Health, University of London (London School of Hygiene and Tropical Medicine), London WC1E 7HT, UK.

Background: Multiple-marker, maternal serum screening (MSS) has been the cornerstone of prenatal diagnosis since the 1980s. While combinations of these markers are used to predict fetal risk of Down syndrome and other genetic conditions, there is some evidence that individual markers may also predict nongenetic pregnancy complications, particularly those related to placental dysfunction. The objective of this meta-analysis was to investigate the utility of false-positive, second-trimester MSS for Down syndrome as a marker of placentally mediated complications amongst singleton pregnancies globally. Read More

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Association of prenatal stress due to maternal bereavement with intellectual disability in the offspring.

Psychosom Med 2021 Jul 23. Epub 2021 Jul 23.

Clincial Research Centre, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China Department of Clinical Medicine-Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark Department of Biostatistics, School of Public Health, and The Key Laboratory of Public Health Safety of Ministry of Education, Fudan University, Shanghai, China Department of Obstetrics, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden Centre for Public Health Sciences, University of Iceland, Iceland Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, Massachusetts, USA. Department of Women & Children's Health Care, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China Ministry of Education - Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Objective: To examine the association of mother's loss of a close relative before or during pregnancy with intellectual disability (ID) in the offspring.

Methods: We performed a nationwide population-based cohort study based on Danish national registries. All live-born singletons born in Denmark during 1978-2016 (n = 2,) were followed started from birth until up to 38 years of age. Read More

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Preconception Substance Use and Risk of Unintended Pregnancy: Pregnancy Risk Assessment Monitoring System 2016-17.

J Addict Med 2021 Jul 29. Epub 2021 Jul 29.

Department of Epidemiology, West Virginia University School of Public Health, Morgantown, WV (SS, KEI, TMR); Department of Pediatrics, West Virginia University School of Medicine, Morgantown, (AU, LC); The West Virginia Clinical and Translational Science Institute (WVCTSI), Health Science Center, West Virginia University, Morgantown, WV (WF).

Objective: This study examined the association between preconception substance use and unintended pregnancy in a large, nationally representative sample of women.

Methods: In this cross-sectional study, we used data from the Pregnancy Risk Assessment Monitoring System (PRAMS) comprising, 74,543 women who had birth during 2016-17. Logistic regression was used to assess the independent association of unintended pregnancy overall and by subtypes to preconception substance use (smoking and other nicotine/tobacco use, alcohol consumption, and use of cannabis, illicit/recreational drugs) and specific medication including prescription opioids, antidepressants and over the counter pain relief. Read More

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Local Anesthetic Systemic Toxicity during Labor, Birth, and Immediate Postpartum: Clinical Review.

MCN Am J Matern Child Nurs 2021 Jul 30. Epub 2021 Jul 30.

Dr. Nicole D. Mock is a Nurse Anesthetist, Department of Anesthesiology, Harnett Health, Dunn, NC. Dr. Mock can be reached via email at Dr. Kellie M. Griggs is an Assistant Professor, Department of Academic Nursing, Wake Forest University School of Medicine, Winston-Salem, NC. Dr. Lisa A. Mileto is Director for Doctoral Education, and Assistant Professor, Department of Academic Nursing, Wake Forest University School of Medicine, Winston-Salem, NC.

Abstract: Local anesthetic systemic toxicity (LAST) is a life-threatening event caused by elevated local anesthetic plasma concentration. It is often unrecognized or misdiagnosed. Peripartum women are at increased risk for toxicity due to pregnancy-related physiological changes. Read More

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Knowing your audience: Investigating stillbirth knowledge and perceptions in the general population to inform future public health campaigns.

Women Birth 2021 Jul 29. Epub 2021 Jul 29.

Curtin Medical School, Curtin University, Bentley, WA, Australia; UniSA Clinical and Health Sciences, University of South Australia, Adelaide, South Australia, Australia.

Background: The prevalence of stillbirth in many high income countries like Australia has remained unchanged for over 30 years. The 2018 Australian government Senate Select Committee on Stillbirth Research and Education highlighted the need for a public health campaign to encourage public conversations and increase awareness. However, there is little evidence about the community's knowledge and perceptions towards pregnancy and stillbirth, nor their aspirations for a public health campaign. Read More

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Severe fetal anemia and hydrops fetalis associated with compound heterozygosity for Hb Zurich-Albisrieden (:c.178G>C) and Hb Quong Sze (:c.377T>C).

J Int Med Res 2021 Jul;49(7):3000605211031429

Medical Genetic Center, 90405Guangdong Women and Children Hospital, Guangdong Women and Children Hospital, Guangzhou, Guangdong, China.

We report on a fetus with cardiomegaly and increased middle cerebral artery-peak systolic velocity at 25 weeks of gestation. Severe fetal anemia (hemoglobin (Hb) level 37 g/L) was confirmed by cordocentesis. Hb analysis showed that Hb Bart's was 9% in cord blood. Read More

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Relationship between vitamin D status in the first trimester of the pregnancy and gestational weight gain: a mediation analysis.

Arch Gynecol Obstet 2021 Jul 31. Epub 2021 Jul 31.

Reproductive Endocrinology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, No 24, Parvane Street, Yaman Street, Velenjak, Tehran, Iran.

Purpose: To evaluate the total, and direct effects of vitamin D, measured by circulating 25-hydroxyvitamin D [25(OH)D] levels, on GWG after adjustment for confounding variables, and then assess the indirect effects by demonstrating the role of gestational age at birth as a mediator in this association.

Methods: Data collected in "Khuzestan Vitamin D Deficiency Screening Program in Pregnancy" were used for the present study; it included the data of 900 pregnant women referred to the health centers of Shushtar (Khuzestan Province, Iran), whose vitamin D status during the third trimester of pregnancy was available. A mediation analysis was applied to detect the causal relationship between serum level of 25(OH)D, covariates (maternal age, parity, education level, and baseline maternal weight), mediator (gestational age), and outcome (GWG). Read More

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Maternal selenium intake and selenium status during pregnancy in relation to preeclampsia and pregnancy-induced hypertension in a large Norwegian Pregnancy Cohort Study.

Sci Total Environ 2021 Jul 27;798:149271. Epub 2021 Jul 27.

Region Västra Götaland, Sahlgrenska University Hospital, Department of Obstetrics and Gynaecology, Gothenburg, Sweden; Department of Obstetrics and Gynaecology, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden. Electronic address:

Background: Pregnancy-induced hypertensive disorders (PIHD), including preeclampsia, cause maternal and perinatal morbidity and mortality worldwide. Several studies have linked selenium supplementation and selenium status to the risk of preeclampsia, but there are no published prospective population-based studies examining associations between dietary selenium intake and preeclampsia.

Aim: To examine associations between selenium intake from diet and supplements and selenium blood status and PIHD incidence, with sub-analyses for pregnancy-induced hypertension (PIH) and preeclampsia, in a large pregnancy cohort. Read More

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Effects of snack intake during pregnancy and lactation on reproductive outcome in mild hyperglycemic rats.

Physiol Behav 2021 Jul 29:113544. Epub 2021 Jul 29.

Department of Physiology, Institute of Biosciences of the University of São Paulo (IB/USP), Rua do Matão, trav. 14, 321, Cidade Universitária, São Paulo, São Paulo, Brazil, 05508-090; São Paulo State University (Unesp), Institute of Biosciences, Department of Structural and Functional Biology, Rua Prof. Dr. Antonio Celso Wagner Zanin, s/n, Botucatu, São Paulo, Brazil, 18618-689.

Metabolic disorders, like diabetes, as well as maternal diet, alter nutrient availability in utero, inducing adaptations in the offspring. Whether the effects of maternal hyperglycemia are modulated by diet, however, has yet to be explored. In the current study, we examined this issue by giving females rats, treated neonatally with STZ to induce mild hyperglycemia, and control littermates either ad libitum access to standard chow (Control n = 17; STZ n = 16) or standard chow and snacks (Control-snack n = 18; STZ-snack n = 19) (potato chips and a red fruit-flavored sucrose syrup solution 1. Read More

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Endometrial thickness in the prediction of neonatal adverse outcomes in frozen cycles for singleton pregnancies.

Reprod Biomed Online 2021 Apr 24. Epub 2021 Apr 24.

Department of Obstetrics and Gynaecology, Monash University, Clayton Victoria, Australia.

Research Question: Does endometrial thickness (EMT) predict adverse neonatal outcomes in singleton pregnancies after in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) frozen embryo transfer (FET)?

Design: This retrospective study involved 13,383 women undergoing IVF/ICSI FET cycles between January 2010 and December 2018 in Women's Hospital of Zhejiang University. The primary outcome was preterm delivery (PTD). The secondary outcomes were small for gestational age (SGA), large for gestational age (LGA) and low birthweight (LBW). Read More

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Factors associated with modern contraceptive use among women with no fertility intention in sub-Saharan Africa: evidence from cross-sectional surveys of 29 countries.

Contracept Reprod Med 2021 Aug 1;6(1):22. Epub 2021 Aug 1.

Department of Population and Health, University of Cape Coast, Cape Coast, Ghana.

Background: In sub-Saharan Africa, the majority of women of reproductive age who want to avoid pregnancy do not use any method of contraception. This study sought to determine the factors associated with  modern contraceptive use among women with no fertility intention in sub-Saharan Africa.

Methods: This study used data from the Demographic and Health Surveys of 29 countries in sub-Saharan Africa. Read More

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Induction of labour as compared with spontaneous labour in low-risk women: A multicenter study in Catalonia.

Sex Reprod Healthc 2021 Jul 26;29:100648. Epub 2021 Jul 26.

School of Health Sciences Blanquerna, Universitat Ramon Llull, Carrer Padilla 326, 08025 Barcelona, Spain; Catalan Health Service, Government of Catalonia, Travessera de les Corts 131, 08028 Barcelona, Spain. Electronic address:

Objective: To compare birth and neonatal outcomes in low-risk women undergoing induced labour with those undergoing spontaneous onset.

Methods: This retrospective multicentre study included 30 public maternity hospitals in Catalonia between 2016 and 2017. The study population consisted of 5,717 women. Read More

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Pregnancy outcomes during the COVID-19 pandemic in Canada, March to August 2020.

J Obstet Gynaecol Can 2021 Jul 28. Epub 2021 Jul 28.

Department of Obstetrics and Gynaecology, BC Children's and Women's Hospital and Health Centre, and the University of British Columbia, Vancouver, Canada; School of Population and Public Health, University of British Columbia, Vancouver, Canada.

Objective: Several studies have documented changes in the rates preterm birth and stillbirth during the COVID-19 pandemic. We carried out a study to examine obstetric intervention, preterm birth, and stillbirth rates in Canada from March to August 2020.

Methods: The study included all singleton hospital deliveries in Canada (excluding Québec) from March to August 2020 (and March to August for the years 2015-2019) with information obtained from the Canadian Institute for Health Information. Read More

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The relation between cigarette smoking with delivery outcomes. An evaluation of a database of more than nine million deliveries.

J Perinat Med 2021 Jul 30. Epub 2021 Jul 30.

Division of Reproductive Endocrinology and Infertility, McGill University Health Care Center, Montreal, QC, Canada.

Objectives: Smoking in pregnancy is associated with an increased risk of preterm birth (PTB), intrauterine growth restriction, placental abruption and perinatal death. The association between smoking and other delivery outcomes, such as chorioamnionitis, mode of delivery or post partum hemorrhage (PPH), however, is insufficient as only few studies addressed these issues. The aim of the study was to evaluate the association between prenatal smoking and delivery outcomes in a large database, while controlling for confounding effects. Read More

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The impact of COVID-19 visitor policy restrictions on birthing communities of colour.

J Adv Nurs 2021 Jul 30. Epub 2021 Jul 30.

School of Social Work, University of Washington, Seattle, Washington, USA.

Aims: To explore the experiences of care for pregnant and birthing people, and the nurses who cared for them, during the COVID-19 pandemic, with special emphasis on the impact of visitor restrictions policies.

Design: Qualitative study using critical thematic analysis.

Methods: We conducted semi-structured interviews with 15 community members who were pregnant and/or gave birth and 14 nurses who worked in the perinatal setting between April and August 2020. Read More

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