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Ruminant farmers' knowledge, attitude and practices towards zoonotic diseases in Selangor, Malaysia.

Prev Vet Med 2021 Sep 6;196:105489. Epub 2021 Sep 6.

Department of Veterinary Clinical Studies, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400, UPM, Serdang, Selangor, Malaysia. Electronic address:

This study aimed to assess knowledge, attitude and practices about zoonotic diseases and associated factors among ruminant farmers in Selangor, Malaysia. A cross-sectional survey was conducted between January 2018 and December 2020. The survey was developed in English and Malay, validated, administered to ruminant farmers in Selangor. Read More

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September 2021

Seasonal variation, source identification, and risk assessment of organophosphate ester flame retardants and plasticizers in surficial sediments from Liao River estuary wetland, China.

Mar Pollut Bull 2021 Sep 15;173(Pt A):112947. Epub 2021 Sep 15.

Key Laboratory of Regional Environment and Eco-Remediation of Ministry of Education, College of Environment, Shenyang University, Shenyang 110044, China.

Organophosphate ester (OPE) flame retardants and plasticizers in surficial sediments were collected in Liao River estuarine wetland during the dry, flood, and level periods to understand the seasonal variation, potential sources, and environmental risks. The concentrations of ∑OPEs ranged from 19.5 to 67. Read More

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September 2021

Evolution of milk oligosaccharides: Origin and selectivity of the ratio of milk oligosaccharides to lactose among mammals.

Biochim Biophys Acta Gen Subj 2021 Sep 15:130012. Epub 2021 Sep 15.

School of Molecular Bioscience, The University of Sydney, Sydney, NSW 2006, Australia.

Background: The carbohydrate fraction of mammalian milk is constituted of lactose and oligosaccharides, most of which contain a lactose unit at their reducing ends. Although lactose is the predominant saccharide in the milk of most eutherians, oligosaccharides significantly predominate over lactose in the milk of monotremes and marsupials.

Scope Of Review: This review describes the most likely process by which lactose and milk oligosaccharides were acquired during the evolution of mammals and the mechanisms by which these saccharides are digested and absorbed by the suckling neonates. Read More

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September 2021

Transplantion of predominant Lactobacilli from native hens to commercial hens could indirectly regulate their ISC activity by improving intestinal microbiota.

Microb Biotechnol 2021 Sep 18. Epub 2021 Sep 18.

Department of Veterinary Medicine, Zhejiang Provincial Key Laboratory of Preventive Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, 310058, China.

In poultry, HyLine (HL) Hens are known for their excellent laying performance. However, ZhenNing (ZN) Hens, a native chicken breed in China, are known for their unique flavour. The intestinal mucosa, which is the main organ for nutrient absorption, could affect livestock product quality. Read More

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September 2021

Actinomyces capricornis sp. nov., isolated from the oral cavity of a Japanese serow.

Microbiol Immunol 2021 Sep 18. Epub 2021 Sep 18.

Department of Microbiology and Immunology, Chiba, 271-8587, Japan.

A novel gram-positive, facultatively anaerobic, rod-shaped, non-spore forming, non-motile organism was isolated from a Japanese serow oral cavity. Designated strain MAS-1 , it is most closely related to Actinomyces bowdenii DSM 15435 , with which it shares 98.07% sequence homology in the 16S rRNA gene. Read More

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September 2021

Colonization and Development of the Fecal Microflora of South China Tiger Cubs (Panthera tigris amoyensis) by Sequencing of the 16S rRNA Gene.

Microb Physiol 2021 Sep 14:1-12. Epub 2021 Sep 14.

College of Life Science, Longyan University, Longyan, China.

Postnatal colonization and development of the gut microbiota is linked to health and growth. A comprehensive understanding of the postnatal compositional changes and development of the microbial community is helpful to understand the gut health and improve the survival rate of South China tiger cubs (Panthera tigris amoyensis). Fecal samples from three tiger cubs were collected on the day of birth in 2018 (June 17-21 [G0], July 18 [G1], July 31 [G2], and August 7 [G3]). Read More

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September 2021

A machine learning approach to determine the prognosis of patients with Class III malocclusion.

Am J Orthod Dentofacial Orthop 2021 Sep 14. Epub 2021 Sep 14.

Orthodontics, Adams School of Dentistry, The University of North Carolina at Chapel Hill, Chapel Hill, NC. Electronic address:

Introduction: The conundrum of determining how to treat a patient with Class III malocclusion is significant, creating a burden on the patient and challenging the orthodontist. The objective of this study was to employ a statistical prediction model derived from our previous cephalometric data on 5 predominant subtypes of skeletal Class III malocclusion to test the hypothesis that Class III subtypes are associated with treatment modalities (eg, surgical vs nonsurgical) and treatment outcome.

Methods: Pretreatment lateral cephalometric records of 148 patients were digitized for 67 cephalometric variables, and measurements were applied to a mathematical equation to assign a Class III subtype. Read More

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September 2021

Compound heterozygous mutations in the LTBP2 gene associated with microspherophakia in a Chinese patient: a case report and literature review.

BMC Med Genomics 2021 Sep 17;14(1):227. Epub 2021 Sep 17.

Research Laboratory of Ophthalmology and Vision Sciences, State Key Laboratory of Biotherapy, West China Hospital of Sichuan University, Chengdu, 610000, Sichuan Province, China.

Background: Microspherophakia (MSP, OMIM 251,750) is a rare inherited autosomal recessive eye disorder characterized by small spherically shaped lens. Several studies have indicated that the transforming growth factor-beta (TGF-beta) binding proteins(LTBP2) gene mutation is the predominant cause of MSP. In our study, novel compound heterozygous mutations in the LTBP2 gene associated with MSP were reported, which was different from previous reported homozygous mutations. Read More

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September 2021

Prevalence and risk factors associated with asymptomatic malaria among school children: repeated cross-sectional surveys of school children in two ecological zones in Ghana.

BMC Public Health 2021 Sep 17;21(1):1697. Epub 2021 Sep 17.

Department of Epidemiology, College of Health Sciences, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.

Background: Asymptomatic Plasmodium infections significantly drive malaria transmission and impact control and elimination strategies, but are largely uncharacterized. We investigated the prevalence and risk factors of asymptomatic malaria infections to inform malaria control strategies in Ghana.

Method: Five cross-sectional surveys were conducted at the end of the peak transmission season (August-September) on 4892 school children aged between 6 and 14 years in two distinct ecological settings in Ghana between 2013 and 2017. Read More

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September 2021

Clinical relevance of interdental papilla biopsy in chronic erosive gingivitis (desquamative gingivitis): retrospective bicentric study of 148 specimens.

BMC Oral Health 2021 Sep 17;21(1):452. Epub 2021 Sep 17.

Department of Odontology, Saint Roch Hospital, Nice, France.

Background: Chronic erosive gingivitis, also called desquamative gingivitis, defines a clinical picture that can be generated by several inflammatory and immune diseases. Pathology is therefore essential for the differential diagnosis. However, when the gingival lesion is initial, exclusive or predominant, selecting the biopsy site and protocol may be problematic due to tissue fragility. Read More

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September 2021

Identification of C3H2C3-type RING E3 ubiquitin ligase in grapevine and characterization of drought resistance function of VyRCHC114.

BMC Plant Biol 2021 Sep 17;21(1):422. Epub 2021 Sep 17.

College of Horticulture and Plant Protection, Henan University of Science and Technology, Luoyang, 471023, Henan Province, China.

Background: RING is one of the largest E3 ubiquitin ligase families and C3H2C3 type is the largest subfamily of RING, which plays an important role in plant growth and development, and growth and responses to biotic and abiotic stresses.

Results: A total of 143 RING C3H2C3-type genes (RCHCs) were discovered from the grapevine genome and separated into groups (I-XI) according to their phylogenetic analysis, and these genes named according to their positions on chromosomes. Gene replication analysis showed that tandem duplications play a predominant role in the expansion of VvRCHCs family together. Read More

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September 2021

Metal(loid)s diffusion pathway triggers distinct microbiota responses in key regions of typical karst non-ferrous smelting assembly.

J Hazard Mater 2021 Sep 10;423(Pt B):127164. Epub 2021 Sep 10.

School of Water Resource and Environment, Research Center of Environmental Science and Engineering, MOE Key Laboratory of Groundwater Circulation and Environmental Evolution, China University of Geosciences (Beijing), 29 Xueyuan Road, Haidian District, Beijing 100083, China; Equipe Environnement et Microbiologie, MELODY group, Université de Pau et des Pays de l'Adour, E2S-UPPA, IPREM UMR CNRS 5254, BP 1155, 64013 Pau Cedex, France.

Non-ferrous metal(loid)s in region with karst characteristic are highly diffusible, especially by runoff or atmospheric deposition. However, microbiota in response to the diffusing metal(loid)s is still to be understood. In this study, we focused on microbiota across metal(loid)s diffusion pathways around a non-ferrous smelting assembly. Read More

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September 2021

Instruments to evaluate undergraduate healthcare student learning styles globally: A scoping review.

Nurse Educ Today 2021 Sep 11;107:105141. Epub 2021 Sep 11.

Tessália Vieira de Camargo street, 126 - Cidade Universitária, 13083-887 Campinas, SP, Brazil. Electronic address:

Background: Recognizing learning styles is important to maximizing learning outcomes and many instruments are available to investigate learning styles.

Objective: To investigate instruments with evidence of validity and reliability most commonly used to evaluate undergraduate healthcare student learning styles globally.

Method: This scoping review of literature was guided by The Joanna Briggs Institute's recommendations for conducting scoping reviews and the PRISMA-ScR (extension for scoping reviews). Read More

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September 2021

Shorter rapid eye movement sleep duration in children with attention-deficit /hyperactivity disorder: the impact on quality of life.

Sleep Med 2021 Jul 30;87:77-84. Epub 2021 Jul 30.

Institute of Psychiatry, Faculty of Medicine, Ain-Shams University, Cairo, Egypt.

Objectives: The relationship of sleep with attention deficit hyperactivity disorder (ADHD) remains complex and unclear. The current study aimed to compare the subjective and objective sleep parameters among children with and without ADHD. Moreover, to address the effect of sleep parameters on the quality of life (QoL). Read More

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Joint involvement in Noonan syndrome.A retrospective paediatric descriptive study.

Joint Bone Spine 2021 Sep 14:105270. Epub 2021 Sep 14.

Rheumatology Department, CHU Cavale Blanche, Center of Autoimmune Rare Diseases (CERAINO), Brest, France; UMR1227, INSERM, Université de Bretagne Occidentale, Brest, France. Electronic address:

Objectives: Noonan syndrome is a rare genetic disorder characterized mainly by congenital heart disease, occasional intellectual disability, and varied orthopaedic, rheumatological and haematologic anomalies. Despite potentially serious functional consequences, joint involvement has been rarely studied in the literature. Our objective was to perform a retrospective study evaluating the prevalence and characteristics of joint involvement in Noonan syndrome. Read More

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September 2021

Crosstalk between estrogen, dendritic cells, and SARS-CoV-2 infection.

Rev Med Virol 2021 Sep 17:e2290. Epub 2021 Sep 17.

Faculty of Pharmacy-FFUC, University of Coimbra, Coimbra, Portugal.

The novel coronavirus disease 2019 (Covid-19) first appeared in Wuhan and has so far killed more than four million people worldwide. Men are more affected than women by Covid-19, but the cellular and molecular mechanisms behind these differences are largely unknown. One plausible explanation is that differences in sex hormones could partially account for this distinct prevalence in both sexes. Read More

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September 2021

Retention Force of Glass Ionomer Based Luting Cements with Posterior Primary Zirconium Crowns - A Comparative in Vitro Study.

J Clin Pediatr Dent 2021 Oct;45(4):259-264

Objective: To determine the retentive force of three glass-ionomer luting cements used with prefabricated primary zirconium crowns (PPZCs) and to assess whether the retentive force was dependent on cementation material or different PPZCs brands.

Study Design: Four mandibular right second molar PPZCs were selected, one each from four manufacturers-NuSmile®ZR, Sprig Crowns, Cheng Crowns and Kinder Krowns. Silicone impressions of the outer surface of crowns were taken; stone dies prepared and reduced to fit the corresponding brand. Read More

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October 2021

Spread of ESC-, carbapenem- and colistin-resistant Escherichia coli clones and plasmids within and between food workers in Lebanon.

J Antimicrob Chemother 2021 Sep 17. Epub 2021 Sep 17.

Université de Lyon-ANSES laboratoire de Lyon, Unité Antibiorésistance et Virulence Bactériennes, Lyon, France.

Objectives: Knowledge on the dynamic of MDR Escherichia coli in the human community is still limited, especially in low- and middle-income countries. Our goal was to decipher the dynamics of E. coli lineages and plasmids resistant to ESC, carbapenem and colistin within and between food workers in Lebanon using genomic-based approaches. Read More

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September 2021

Choline acts during preimplantation development of the bovine embryo to program postnatal growth and alter muscle DNA methylation.

FASEB J 2021 Oct;35(10):e21926

Department of Animal Sciences and D.H. Barron Reproductive and Perinatal Biology Research Program, and Genetics Institute, University of Florida, Gainesville, Florida, USA.

The preimplantation period of embryonic development can be a key window for programming of postnatal development because extensive epigenetic remodeling occurs during this time. It was hypothesized that modification of one-carbon metabolism of the bovine embryo by addition of the methyl-donor choline to culture medium would change postnatal phenotype through epigenetic modification. Embryos produced in vitro were cultured with 1. Read More

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October 2021

International Changes in COVID-19 Clinical Trajectories Across 315 Hospitals and 6 Countries: a 4CE Consortium Study.

J Med Internet Res 2021 Sep 2. Epub 2021 Sep 2.

Institute for Biomedical Informatics, University of Kentucky, Lexington, US.

Background: Many countries have experienced two predominant waves of COVID-19-related hospitalizations. Comparing the clinical trajectories of patients hospitalized in separate waves of the pandemic enables further understanding of the evolving epidemiology, pathophysiology, and healthcare dynamics of the COVID-19 pandemic.

Objective: In this retrospective cohort study, we analyzed electronic health record (EHR) data from patients with SARS-CoV-2 infections hospitalized in participating healthcare systems representing 315 hospitals across six countries. Read More

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September 2021

Gambling behaviors during COVID-19: a narrative review.

J Addict Dis 2021 Sep 17:1-9. Epub 2021 Sep 17.

Texas Tech University Health Sciences Center, Lubbock, TX, USA.

The COVID-19 pandemic has ushered the world into unforeseen circumstances, prompting the authorities to impose restrictions and cut back various events including many gambling avenues. Professional sports have been postponed, land casinos are closed, and social distancing has shut home games down. The present narrative overview has addressed the following changes in gambling behavior since the start of the pandemic: - a) Change in the number of gamblers and intensity of gambling b) differences among various types of gambling modalities (land-based, horse betting, casino, online). Read More

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September 2021

A critical appraisal of tau-targeting therapies for primary and secondary tauopathies.

Alzheimers Dement 2021 Sep 17. Epub 2021 Sep 17.

Department of Neuroscience, Istituto di Ricerche Farmacologiche "Mario Negri" IRCCS, Milan, Italy.

Introduction: Primary tauopathies are neurological disorders in which tau protein deposition is the predominant pathological feature. Alzheimer's disease is a secondary tauopathy with tau forming hyperphosphorylated insoluble aggregates. Tau pathology can propagate from region to region in the brain, while alterations in tau processing may impair tau physiological functions. Read More

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September 2021

Reappraisal of the historical myopia epidemic in native Arctic communities.

Ophthalmic Physiol Opt 2021 Sep 17. Epub 2021 Sep 17.

Dr Iribarren Eye Consultants, Buenos Aires, Argentina.

Purpose: This study was developed to explain the extraordinary rise in myopia prevalence beginning after 1950 in Indigenous Arctic communities considering recent findings about the risk factors for school myopia development. Myopia prevalence changed drastically from a historical low of less than 3% to more than 50% in new generations of young adults following the Second World War. At that time, this increase was attributed to concurrent alterations in the environment and way of life which occurred in an aggressive programme of de-culturalization and re-acculturation through residential school programmes that introduced mental, emotional and physical stressors. Read More

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September 2021

Electropolymerized 1D Growth Coordination Polymer for Hybrid Electrochromic Aqueous Zinc Battery.

Adv Sci (Weinh) 2021 Sep 17:e2101944. Epub 2021 Sep 17.

School of Materials Science and Engineering, Nanyang Technological University, Singapore, 639798, Singapore.

Organic materials are always viewed as promising electrochromic (EC) materials due to their synthetic versatility, color tunability, ready processability, and derivability from sustainable feedstocks. Most organic materials, however, are prone to undesirable redox side reactions in the presence of oxygen and water. As such, redox-active organic layers are often used in tandem with organic electrolytes to preserve their electrochemical stability. Read More

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September 2021

Systematic Review: Cardiac Metastasis of Lingual Squamous Cell Carcinoma.

Spartan Med Res J 2021 30;6(2):27297. Epub 2021 Aug 30.

Metro Health Hospital-University of Michigan, Wyoming, Michigan, USA.

Introduction: Lingual squamous cell carcinoma (LSCC) is an aggressive malignancy that carries significant mortality risk and the potential for cardiac metastasis. The authors performed a systematic review designed to characterize disease progression of LSCC cardiac metastasis by evaluating patient demographics, characteristics, management, and clinical outcomes.

Methods: Two authors independently screened articles in Embase, PubMed, and Cochrane Database of Systematic Reviews up until December 2019 for study eligibility. Read More

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Pulmonary artery pressure is associated with mid-term major adverse cardiovascular events and postprocedure pericardial effusion in atrial fibrillation patients undergoing left atrial appendage occlusion.

Ann Transl Med 2021 Aug;9(16):1324

Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Disease, Shanghai, China.

Background: Patients with nonvalvular atrial fibrillation (NVAF) undergoing left atrial appendage occlusion (LAAO) are at high risk of stroke or bleeding. However, risk factors for their adverse cardiovascular events remain largely unknown. Pulmonary hypertension has been shown to be related to poor prognosis in many heart diseases. Read More

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Health benefits of docosahexaenoic acid and its bioavailability: A review.

Food Sci Nutr 2021 Sep 23;9(9):5229-5243. Epub 2021 Jul 23.

Roquette Management (Shanghai) Co., Ltd. R&D China Shanghai China.

Docosahexaenoic acid (DHA) is the predominant omega-3 long-chain polyunsaturated fatty acid found in human brain and eyes. There are a number of studies in the literature showing the health benefits of DHA. It is critical throughout all life stages from the need for fetal development, the prevention of preterm birth, and the prevention of cardiovascular disease to the improvements in the cognitive function and the eye health of adults and elderly. Read More

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September 2021

Occurrence and antimicrobial resistance of isolated from retail meats in Anhui, China.

Food Sci Nutr 2021 Sep 16;9(9):4701-4710. Epub 2021 Jul 16.

Engineering Research Center of Bio-process Ministry of Education Hefei University of Technology Hefei China.

is considered one of the major foodborne pathogens associated with severe infections. Little attempt has been focused on the distribution of in retail meats and the analysis of its phenotypic characteristics in Anhui Province. The aim of this study was to characterize the prevalence of serovars, antimicrobial susceptibility, antimicrobial resistance genes, and virulence genes in recovered from retail meats in Anhui, China. Read More

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September 2021

Succession of Fungal Communities at Different Developmental Stages of Cabernet Sauvignon Grapes From an Organic Vineyard in Xinjiang.

Front Microbiol 2021 31;12:718261. Epub 2021 Aug 31.

Food College, Shihezi University, Shihezi, China.

Fungi present on grape surface considerably impact grape growth and quality. However, information of the fungal community structures and dynamics on the worldwide cash crop, the Cabernet Sauvignon grape, from the budding to ripening stages remains limited. Here, we investigated the succession of fungal communities on Cabernet Sauvignon grapes from an organic vineyard in Xinjiang, China at different developmental stages high-throughput sequencing combined with multivariate data analysis. Read More

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RNA-Based Analysis Reveals High Diversity of Plant-Associated Active Fungi in the Atmosphere.

Front Microbiol 2021 31;12:683266. Epub 2021 Aug 31.

State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan Agricultural University, Kunming, China.

Fungi are ubiquitous in nature; that is, they are present everywhere on the planet; understanding the active state and functional capacity of airborne microbes associated with health of human, animal, and plant is critical for biosafety management. Here, we firstly and directly proved that there were about 40% active fungi in the air rRNA amplicon sequencing and imaging flow cytometry simultaneously. Amplicon sequencing analysis showed differences between structures of active and total fungal community; Ascomycota were dominant in the active community, while Basidiomycota have low transcriptional activity across all samples. Read More

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