112 results match your criteria predictors psd


The incidence and risk factors for venous thromboembolic events in patients with psoriasis and psoriatic arthritis.

Semin Arthritis Rheum 2021 Apr 18;51(3):547-552. Epub 2021 Apr 18.

Division of Rheumatology, Women's College Hospital, Toronto, ON, Canada; Department of Medicine, University of Toronto, Toronto, ON, Canada. Electronic address:

Objectives: The risk of arterial vascular events is increased in patients with psoriatic disease (PsD), however, limited information exists about the risk of venous thromboembolism (VTE) in these patients. We assessed the incidence and risk factors for VTE in patients with PsD.

Methods: A multicentre cohort study was conducted involving patients with PsD followed prospectively from 1994 to 2020. Read More

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Prevalence and predictors of new onset depression in the acute phase of stroke.

Asian J Psychiatr 2021 May 6;59:102636. Epub 2021 Apr 6.

Department of Medicine, University of Sri Lanka, Sri Lanka.

Introduction: Post-stroke depression (PSD) is known to be associated with poor functional outcome and high mortality. There is limited data on the prevalence and associated factors of depression in the acute phase after stroke.

Objectives: To determine the prevalence of PSD in the acute phase and its correlates among patients with stroke in a tertiary care hospital in Sri Lanka. Read More

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Layer-specific strain and dyssynchrony index alteration in new-onset systemic lupus erythematosus patients without cardiac symptoms.

Quant Imaging Med Surg 2021 Apr;11(4):1271-1283

Department of Rheumatology, Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.

Background: Layer-specific speckle-tracking echocardiography (STE) is a noninvasive approach that assesses subclinical left ventricular dysfunction. We aimed to investigate the (I) alteration of layer-specific STE parameters and the dyssynchrony index; and (II) the disease parameters associated with layer-specific STE change in drug-naïve patients with new-onset systemic lupus erythematosus (SLE) without cardiac symptoms.

Methods: Thirty-five drug-naïve patients with new-onset SLE and twenty-five healthy controls were enrolled. Read More

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Mental health and psychosocial support in conflict: children's protection concerns and intervention outcomes in Syria.

Confl Health 2021 Apr 1;15(1):19. Epub 2021 Apr 1.

Division of Psychology, Department of Life Sciences, College of Health, Medicine and Life Sciences, Brunel University London, Kingston Lane, Uxbridge, London, UB8 3PH, UK.

Child protection and mental health during conflict intersects with a variety of adverse conflict-related factors, and intervention outcomes in the field are often difficult to predict. Using the casefiles of 376 school children registered in a Mental Health and Psychosocial Support (MHPSS) project in the Northwest governorate of Idleb in Syria, this study aimed to determine (i) the rates of various protection concerns (potential mental health conditions, psychosocial deprivation issues, and social, behavioural and emotional issues) for students enrolled in this project, (ii) whether the rates of any of the protection concerns varied between children and adolescents, or between boys and girls, and (iii) which of the identified demographic and protection sector factors predicted the presence of potential mental health conditions and MHPSS intervention outcomes. MHPSS interventions (including individual MHPSS sessions tailored for children in conflict, resilience building activities, tutoring, peer building activities, community awareness, and other tailored services) were implemented at schools operated by the UK-based organization, Syria Relief. Read More

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Risk and Predictors of Depression Following Acute Ischemic Stroke in the Elderly.

Neurology 2021 04 15;96(17):e2184-e2191. Epub 2021 Mar 15.

From the Icahn School of Medicine at Mount Sinai (N.M., J.E.); Department of Neurology (L.K.S., S.T., N.J., M.D.), Icahn School of Medicine at Mount Sinai, New York, NY; and University of Pennsylvania Health System (A.K.), Philadelphia.

Objective: We sought to comprehensively evaluate predictors of poststroke depression (PSD) in the United States and to compare PSD to post-myocardial infarction (MI) depression to determine whether ischemic stroke uniquely elevates risk of depression.

Methods: This is a retrospective cohort study of 100% deidentified inpatient, outpatient, and subacute nursing Medicare data from 2016 to 2017 for US patients ≥65 years of age from July 1, 2016, to December 31, 2017. We calculated Kaplan-Meier unadjusted cumulative risk of depression up to 1. Read More

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Prehabilitative exercise hastens recovery from isoflurane in diabetic and non-diabetic rats.

Neurosci Lett 2021 04 8;751:135808. Epub 2021 Mar 8.

Neuroscience Program, Emory University, Atlanta, GA, USA; School of Medicine, Emory University, Atlanta, GA, USA; Center for Visual and Neurocognitive Rehabilitation, Atlanta VA Health Care System, Decatur, GA, USA; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA; Department of Anesthesiology, Emory University School of Medicine, Atlanta, GA, USA; Department of Anesthesiology, Columbia University Medical Center, New York, NY, USA. Electronic address:

Diabetes has been demonstrated to be one of the strongest predictors of risk for postoperative delirium and functional decline in older patients undergoing surgery. Exercise is often prescribed as a treatment for diabetic patients and regular physical activity is hypothesized to decrease the risk of postoperative cognitive impairments. Prior studies suggest that anesthetic emergence trajectories and recovery are predictive of risk for later postoperative cognitive impairments. Read More

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Delirium REduction after administration of melatonin in acute ischemic stroke (DREAMS): A propensity score-matched analysis.

Eur J Neurol 2021 Mar 3. Epub 2021 Mar 3.

Department of Neurology & Stroke, Eberhard-Karls University of Tübingen, Tübingen, Germany.

Background And Purpose: Poststroke delirium (PSD) comprises a common and severe complication after stroke. However, treatment options for PSD remain insufficient. We investigated whether prophylactic melatonin supplementation may be associated with reduced risk for PSD. Read More

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Effect of intravenous alteplase on post-stroke depression in the WAKE UP trial.

Eur J Neurol 2021 Mar 3. Epub 2021 Mar 3.

Klinik und Poliklinik für Neurologie, Kopf- und Neurozentrum, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.

Background And Purpose: The aim was to study the effect of intravenous alteplase on the development of post-stroke depression (PSD) in acute stroke patients, and to identify predictors of PSD.

Methods: This post hoc analysis included patients with unknown onset stroke randomized to treatment with alteplase or placebo in the WAKE-UP trial (ClinicalTrials.gov number, NCT01525290), in whom a composite end-point of PSD was defined as a Beck Depression Inventory ≥10, medication with an antidepressant, or depression recorded as an adverse event. Read More

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How demographic and clinical characteristics contribute to the recovery of post-stroke dysphagia?

Medicine (Baltimore) 2021 Jan;100(4):e24477

Department of Rehabilitation Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Abstract: According to the analysis to find out how demographic and clinical characteristics influent the dysphagia outcome after stroke, furthermore, giving some insights to clinical treatment.One hundred eighty post-stroke dysphagia (PSD) patients were enrolled in this retrospective study at the stroke rehabilitation department. The outcome measurements are beside water swallow test at discharge and length of stay at hospital. Read More

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January 2021

Course and Recognition of Poststroke Delirium: A Prospective Noninferiority Trial of Delirium Screening Tools.

Stroke 2021 Jan 31;52(2):471-478. Epub 2020 Dec 31.

Department of Neurology, University Medicine Greifswald, Germany (R.F., S.W., T.A., R.K., C.W., B.v.S.).

Background And Purpose: Poststroke delirium (PSD) is an independent predictor of unfavorable outcome. Despite its individual and socioeconomic burden, its frequency, clinical course, and routine detection remain unresolved. This study aimed to assess psychometric properties of established delirium screening tools and investigate the natural course of PSD. Read More

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January 2021

Prevalence, predictors, and prognoses of prestroke neuropsychiatric symptoms at 3 months poststroke.

Int Psychogeriatr 2020 Dec 30:1-8. Epub 2020 Dec 30.

Department of Psychiatry, College of Medicine, University of Ibadan, Ibadan, Nigeria.

Objectives: Prior neuropsychiatric disturbances are risk factors for stroke. There is a knowledge gap on the predictors of prestroke psychopathology, as well as their association with stroke outcomes in survivors living in low- and middle-income countries (LMICs). We estimated prevalence, predictors, and association of prestroke neuropsychiatric symptoms with poststroke depression (PSD), disability, and mortality. Read More

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December 2020

Prognostic value of left ventricular mechanical dyssynchrony in hypertrophic cardiomyopathy patients with low risk of sudden cardiac death.

Nucl Med Commun 2021 Feb;42(2):182-189

Department of Applied Computing, Michigan Technological University, Houghton, Michigan, USA.

Purposes: This study aims to explore the prognostic value of left ventricular mechanical dyssynchrony (LVMD) in hypertrophic cardiomyopathy (HCM) patients with low risk of sudden cardiac death (SCD).

Methods: This retrospective study was performed in 50 patients with HCM who underwent Tc-99m sestamibi GSPECT-MPI. All patients were at low risk of SCD, defined as HCM risk-SCD scores <6%. Read More

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February 2021

Biomarkers are associated with clinical and endoscopic outcomes with vedolizumab treatment in Crohn's disease.

Therap Adv Gastroenterol 2020 12;13:1756284820971214. Epub 2020 Nov 12.

Inflammatory Bowel Disease Center, Division of Gastroenterology, Department of Medicine, University of California, San Diego, 9500 Gilman Drive, #0956, La Jolla, CA 92093-0956, USA.

Background: Vedolizumab, an α4β7 integrin antagonist, is an effective therapy for Crohn's disease (CD). Biomarkers are needed to guide therapy and predict outcomes. This study evaluated biomarker concentrations and outcomes in patients with CD undergoing vedolizumab treatment. Read More

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November 2020

Clinical and gated SPECT MPI parameters associated with super-response to cardiac resynchronization therapy.

J Nucl Cardiol 2020 Nov 5. Epub 2020 Nov 5.

Emory University, Atlanta, GA, USA.

Purpose: We sought to evaluate the behavior of cardiac mechanical synchrony as measured by phase SD (PSD) derived from gated MPI SPECT (gSPECT) in patients with super-response after CRT and to evaluate the clinical and imaging characteristics associated with super-response.

Methods: 158 subjects were evaluated with gSPECT before and 6 months after CRT. Patients with an improvement of LVEF > 15% and NYHA class I/II or reduction in LV end-systolic volume > 30% and NYHA class I/II were labeled as super-responders (SR). Read More

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November 2020

Pre-Stroke Depression in Ghana and Nigeria: Prevalence, Predictors and Association With Poststroke Depression.

J Geriatr Psychiatry Neurol 2020 Oct 19:891988720968274. Epub 2020 Oct 19.

University of California, San Francisco, CA, USA.

Objectives: Depression is a risk factor for stroke. There is a knowledge gap on the predictors of prestroke depression in stroke survivors living in low- and middle-income countries (LMICs). We estimated prevalence and predictors of prestroke depression, as well as its association with poststroke depression (PSD) in the largest study of stroke in Africa. Read More

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October 2020

The Prevalence and Predictors of Post-Stroke Depression and Anxiety During COVID-19 Pandemic.

J Stroke Cerebrovasc Dis 2020 Dec 10;29(12):105315. Epub 2020 Sep 10.

Division of Neurology, Department of Medicine, University of Alberta, Edmonton, AB, Canada.

Introduction: Stroke is associated with a rise in post-stroke depression (PSD) and anxiety (PSA). In this study, we evaluated the impact of COVID-19 pandemic on the rates of PSD and PSA.

Methods: All stroke admissions to two hospitals in Saudi Arabia during two months were prospectively evaluated for PSD and PSA. Read More

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December 2020

PREDICTORS OF EARLY-ONSET DEPRESSION AFTER FIRST-EVER STROKE.

Acta Clin Croat 2020 Mar;59(1):81-90

1Department of Neurology, Clinical Centre of Vojvodina, Novi Sad, Serbia; 2University of Novi Sad, Faculty of Medicine, Department of Neurology, Novi Sad, Serbia; 3Department of Neurology, Clinical Centre of Republic of Srpska, Banjaluka, Republic of Srpska, Bosnia and Herzegovina; 4University of Banjaluka, Faculty of Medicine, Banjaluka, Republic of Srpska, Bosnia and Herzegovina; 5Department of Endocrinology, Diabetes and Metabolic Diseases, Clinical Centre of Vojvodina, Novi Sad, Serbia; 6Global Prevent, Institute for Occupational Health, Novi Sad, Serbia.

Post-stroke depression (PSD) is a severe and frequent stroke complication and one of the crucial factors for the outcome of rehabilitation and life quality after stroke. However, mood disorders frequently remain unnoticed and therefore untreated. The aim of the study was to examine all the potential risk factors and determine the independent predictors of early-onset depression after first-ever stroke, which would help identify high-risk patients, establish early diagnosis and timely treatment that would improve the course and prognosis of this disorder. Read More

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High-dose vitamin B supplementation for persistent visual deficit in multiple sclerosis: a pilot study.

Drug Discov Ther 2020 ;14(3):122-128

Department of Sense Organs, Sapienza University of Rome, Rome, Italy.

The aim of this study is to investigate the potential neuroprotective effect of high-doses vitamins B1, B6 and B12 in patients with relapsing-remitting multiple sclerosis (RRMS) and persistent visual loss after acute optic neuritis (AON). Sixteen patients (20 eyes) diagnosed with RRMS and visual permanent disability following AON were enrolled for the present open, pilot study. Each patient was treated with oral high-doses 300 mg of vitamin B1, 450 mg of vitamin B6 and 1,500 mcg of vitamin B12, as add-on treatment to concomitant disease-modifying therapies (DMTs) for consecutive 90 days. Read More

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Risk Factors for Pseudarthrosis After Surgical Site Infection of the Spine.

Int J Spine Surg 2019 Dec 31;13(6):507-514. Epub 2019 Dec 31.

Rothman Institute, Philadelphia, Pennsylvania.

Background: Pseudarthrosis following spinal fusion is a complication that frequently requires revision surgery. Reported rates of pseudarthrosis after surgical site infection (SSI) range from 30% to 85%, but few studies have identified infection as an independent risk factor for its development. The purpose of this study was to determine the incidence of clinically symptomatic pseudarthrosis in patient who developed SSI following lumbar fusion and to identify factors associated with its development. Read More

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December 2019

Assessment of the Progression of Poststroke Depression in Ischemic Stroke Patients Using the Patient Health Questionnaire-9.

J Stroke Cerebrovasc Dis 2020 Apr 13;29(4):104561. Epub 2020 Jan 13.

The Institute for Stroke and Cerebrovascular Diseases, Department of Neurology, The University of Texas Health Science Center at Houston, Houston, Texas.

Background: Poststroke depression (PSD) affects one-third of stroke patients and is linked with higher stroke morbidity, mortality, and recurrence. Current guidelines do not direct when to screen for PSD, and predictors of PSD are not well understood. We sought to understand progression of PSD symptoms early after ischemic stroke, identify predictors of PSD, and describe the use of antidepressants in PSD. Read More

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TREATMENT OF INTERNAL CAROTID ANEURYSMS USING PIPELINE EMBOLIZATION DEVICES: MEASURING THE RADIATION DOSE OF THE PATIENT AND DETERMINING THE FACTORS AFFECTING IT.

Radiat Prot Dosimetry 2020 Jun;188(3):389-396

Health Research Institute, Department of Life Science and Biotechnology, National Institute of Advanced Industrial Science and Technology (AIST), Central 6, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566, Japan.

The purpose of this study was to measure the peak skin dose (PSD) and bilateral lens doses using radiophotoluminescence glass dosimeters and to determine the factors influencing the radiation dose in cases of cerebral aneurysm treated with pipeline embolization devices (PEDs). The cumulative dose, PSD and right and left lens doses were 3818.1 ± 1604. Read More

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Discriminative factors for post-stroke depression.

Asian J Psychiatr 2020 Feb 5;48:101863. Epub 2019 Nov 5.

Department of Occupational therapy, Musculoskeletal Research Center, School of Rehabilitation Sciences, Isfahan University of Medical Sciences, Isfahan, Iran. Electronic address:

Background: Depression is the most common mood disorder following stroke. It can negatively affects different domains of patient's life. The present study aimed to explore demographic and clinical predictors of post stroke depression and determine discriminative cognitive, motor, and functional factors in stroke patients with and without depression. Read More

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February 2020

Depression and Apathy After Transient Ischemic Attack or Minor Stroke: Prevalence, Evolution and Predictors.

Sci Rep 2019 11 7;9(1):16248. Epub 2019 Nov 7.

Clinical Neuroscience Group of the Biomedical Research Institute of Lleida (IRBLleida), Universitat de Lleida, Lleida, Spain.

Few previous studies have focused on affective impairment after transient ischemic attack (TIA) and/or minor stroke. The aim was to establish the prevalence, evolution and predictors of post-stroke depression (PSD) and post-stroke apathy (PSA) over a 12-month follow-up period. We prospectively included TIA and minor stroke patients (NIHSS ≤4) who had undergone magnetic resonance imaging <7 days. Read More

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November 2019

Severe Periodontitis Is Associated with Early-Onset Poststroke Depression Status.

J Stroke Cerebrovasc Dis 2019 Dec 30;28(12):104413. Epub 2019 Sep 30.

Department of Neurology, The Affiliated Yuebei People's Hospital of Shantou University Medical College, Shaoguan, Guangdong Province, China; Cognitive Impairment Ward of Neurology Department, The Third Affiliated Hospital of Shenzhen University Medical College, Shenzhen, China. Electronic address:

Background: Poststroke depression (PSD) is one of the most common complications after ischemic stroke, and periodontitis is associated with depression. However, whether severe periodontitis is associated with early-onset PSD status remains unknown. In this study, we aimed to investigate whether there is an association between severe periodontitis and PSD status in acute ischemic stroke patients. Read More

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December 2019

The association between serum growth differentiation factor-15 and 3-month depression after acute ischemic stroke.

J Affect Disord 2020 01 10;260:695-702. Epub 2019 Sep 10.

Department of Anus and Bowel, Central Hospital of Zhoukou, Zhoukou, PR China.

Objective: The aim of this study was to assess the association between serum growth differentiation factor-15(GDF-15) and 3-month depression after acute ischemic stroke.

Methods: In this single-center prospective study, patients with first-ever acute ischemic stroke between March 2017 and November 2018 were included. Neurological and neuropsychological evaluations were conducted during the 3-month follow-up. Read More

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January 2020

The dynamics of Poststroke depression among Ghanaians.

J Neurol Sci 2019 Oct 23;405:116410. Epub 2019 Jul 23.

Department of Neurology, University of California, San Francisco, USA.

Objective: The very few published data on post-stroke depression (PSD) among indigenous Africans have covered its prevalence and predictors. We sought to evaluate the dynamics of PSD in a cohort of Ghanaian stroke survivors followed for 9 months after an acute stroke.

Methods: Stroke survivors in this prospective cohort were adults aged >18 years with CT scan confirmed stroke, recruited into a randomized controlled trial to assess the feasibility of an mHealth technology-enabled, nurse guided intervention for blood pressure control. Read More

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October 2019

Serum lipid profiles and post-stroke depression in acute ischemic stroke patients.

Neuropsychiatr Dis Treat 2019 17;15:1573-1583. Epub 2019 Jun 17.

First School of Clinical Medicie, Wenzhou Medical University, Wenzhou, 325000, People's Republic of China.

Post-stroke depression (PSD) is a psychiatric complication after stroke that leads to poorer stroke outcomes. Recent observational studies have indicated that lipid profiles were associated with a higher risk of stroke and depression. This study aims to further explore the possible relationship between serum lipid profiles and the development of PSD. Read More

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[Predictive value of inflammatory indicators for post-stroke depression in patients with ischemic stroke].

Nan Fang Yi Ke Da Xue Xue Bao 2019 Jun;39(6):665-671

Department of Neurology, First Affiliated Hospital of Soochow University, Suzhou 215000, China.

Objective: To investigate the association of venous blood neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) and levels of interleukin-17 (IL-17) and IL-6 at 2 weeks after admission with the occurrence of post-stroke depression (PSD) in patients with first-ever acute ischemic stroke.

Methods: The hospitalized patients with first-ever acute ischemic stroke were recruited consecutively from the Department of Neurology of Yijishan Hospital from March, 2015 to September, 2017. The demographic and baseline clinical data on admission and the imaging data were collected. Read More

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Treatment of Post-Stroke Depression.

Curr Treat Options Neurol 2019 Jun 25;21(7):31. Epub 2019 Jun 25.

Division of Psychiatry, School of Medicine, University of Western Australia, Fremantle Hospital T-7 UWA, Fremantle, 6959, Australia.

Purpose Of Review: This review presents a critical appraisal of current therapeutic strategies for patients with post-stroke depression (PSD). We present the reader with the most recent evidence to support pharmacological, psychosocial, and neuromodulation interventions in PSD. We also discuss the relevance of using antidepressants and psychotherapy to prevent PSD and discuss evidence that antidepressant treatment may reduce mortality after stroke. Read More

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Predictors of Remission of Early-Onset Poststroke Depression and the Interaction Between Depression and Cognition During Follow-Up.

Front Psychiatry 2018 8;9:738. Epub 2019 Jan 8.

Department of Neuropsychiatry and Behavioral Neurology and Clinical Psychology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

This study aimed to examine the rate of remission in individuals experiencing early-onset poststroke depression (PSD) in China and to identify predictors of remission during a 3-month follow-up. This study also explored the interaction between cognitive impairment and depression. A total of 820 patients with PSD from a massive multicenter prospective cohort project in China (PRIOD) were included in the present study. Read More

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January 2019