636 results match your criteria predicting postnatal

Use of an online screening algorithm - Weight, Insulin-derived growth factor 1, Neonatal Retinopathy of Prematurity (WINROP) for predicting retinopathy of prematurity in Indian preterm babies.

Indian J Ophthalmol 2021 May;69(5):1214-1218

Department of Ophthalmology, Government Medical College and Hospital, Chandigarh, India.

Purpose: Inopathy of prematurity (WINROP) Weight, insulin-derived growth factor 1, neonatal ROP algorithm is an online tool that has been validated as a predictor of retinopathy of prematurity (ROP) in various countries. The current study was designed to evaluate the predictive ability of WINROP algorithm (http://winrop.com) using postnatal weight gain in detecting Type 1 ROP in Indian babies. Read More

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Supporting routine psychosocial assessment in the perinatal period: The concurrent and predictive validity of the Antenatal Risk Questionnaire-Revised.

Women Birth 2021 Apr 22. Epub 2021 Apr 22.

Perinatal and Women's Mental Health Unit, St John of God Burwood Hospital, Australia; School of Psychiatry, UNSW Medicine, NSW, Australia; Royal Hospital for Women, NSW, Australia.

Background: Australian clinical practice guidelines support comprehensive psychosocial assessment as a routine component of maternity care.

Aim: To examine the concurrent and predictive validity of the Antenatal Risk Questionnaire-Revised (ANRQ-R) when used across the perinatal period.

Methods: Women completed the ANRQ-R and a diagnostic reference standard (SAGE-SR) in the second and third trimesters and at 3-months postpartum. Read More

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Prenatal diagnosis of exomphalos and prediction of outcome.

Sci Rep 2021 Apr 22;11(1):8752. Epub 2021 Apr 22.

Department of Obstetrics and Gynecology, University Clinic of Carl Gustav Carus Dresden, Technische Universität Dresden, 01307, Dresden, Germany.

The aim of this study was to detect a parameter for predicting prenatal complications or postnatal surgical options after detecting a fetal exomphalos. This was a retrospective analysis of prenatal diagnosis and outcome of fetuses with 41 cases of exomphalos in between 2007 and 2017, considering the measurement of ratios. The 41 fetuses with exomphalos were examined, 34 cases (82. Read More

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Reproducibility of the Edinburgh Postnatal Depression Scale during the Postpartum Period.

Am J Perinatol 2021 Apr 21. Epub 2021 Apr 21.

Department of Obstetrics and Gynecology, Texas Tech University Health Sciences Center, Amarillo, Texas.

Objective:  This study was aimed to evaluate the efficacy of the Edinburgh Postnatal Depression Scale (EPDS) in the immediate postpartum period, which we defined as between 3 and 24 hours postpartum for the purpose of this research. This is such that if it can predict scores obtained at the postpartum visit, it will be an opportunity to access psychiatric services for the patient that may otherwise be more difficult to access in the outpatient setting.

Study Design:  Longitudinal observational study, which included an analysis of 848 consecutive participants screened with the EPDS in the hospital and at the 6-week postpartum visit. Read More

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Early-life childhood obesity risk prediction: A Danish register-based cohort study exploring the predictive value of infancy weight gain.

Pediatr Obes 2021 Mar 29:e12790. Epub 2021 Mar 29.

Public Health and Epidemiology Group, Department of Health Science and Technology, Aalborg University, Aalborg East, Denmark.

Background: Information on postnatal weight gain is important for predicting later overweight and obesity, but it is unclear whether inclusion of this postnatal predictor improves the predictive performance of a comprehensive model based on prenatal and birth-related predictors.

Objectives: To compare performance of prediction models based on predictors available at birth, with and without information on infancy weight gain during the first year when predicting childhood obesity risk.

Methods: A Danish register-based cohort study including 55. Read More

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Predicting Hyperoxia-Induced Lung Injury from Associated Intestinal and Lung Dysbiosis in Neonatal Mice.

Neonatology 2021 Mar 5:106-116. Epub 2021 Mar 5.

Joint Biobank, Office of Human Research, Taipei Medical University, Taipei, Taiwan.

Background: Preclinical studies have demonstrated that hyperoxia disrupts the intestinal barrier, changes the intestinal bacterial composition, and injures the lungs of newborn animals.

Objectives: The aim of the study was to investigate the effects of hyperoxia on the lung and intestinal microbiota and the communication between intestinal and lung microbiota and to develop a predictive model for the identification of hyperoxia-induced lung injury from intestinal and lung microbiota based on machine learning algorithms in neonatal mice.

Methods: Neonatal C57BL/6N mice were reared in either room air or hyperoxia (85% O2) from postnatal days 1-7. Read More

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Recent advances in the diagnosis and management of pre-eclampsia.

Fac Rev 2020 16;9:10. Epub 2020 Nov 16.

Women's Health Academic Centre, King's College London, Westminster Bridge Road, London, SE1 7EH, UK.

Pre-eclampsia is an elusive condition to diagnose and a complex disease to manage. There have been recent developments in prediction, prevention, diagnosis, and management. Risk modelling has been used to identify women at highest risk of developing pre-eclampsia as well as predicting maternal adverse outcomes in confirmed disease. Read More

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November 2020

Evaluation of pro-oxidant antioxidant balance in retinopathy of prematurity.

Eye (Lond) 2021 Mar 1. Epub 2021 Mar 1.

Department of Midwifery, School of Medical Sciences, Tonekabon Branch, Islamic Azad University, Tonekabon, Iran.

Introduction: Retinopathy of prematurity (RoP) is a vasoproliferative disorder caused by the abnormal development of retinal vessels in premature neonates. It is one of the major causes of childhood blindness, which is increasing with the increasing survival rate of low birth weight and premature neonates. This study has aimed to evaluate the role of oxidative stress and peroxidant antioxidant balance (PAB) in the pathogenesis and prediction of RoP. Read More

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Are fetal bilirubin levels associated with the need for neonatal exchange transfusions in hemolytic disease of the fetus and newborn?

Am J Obstet Gynecol MFM 2021 Feb 18;3(3):100332. Epub 2021 Feb 18.

Division of Neonatology, Department of Pediatrics, Leiden University Medical Center, Leiden, the Netherlands (Dr Ree, Ms Oever, and Dr Lopriore).

Background: Fetal bilirubin is routinely measured at our center when taking a pretransfusion blood sample at intrauterine transfusions in hemolytic disease of the fetus and newborn. However, the clinical value of fetal bilirubin assessment is not well known, and the information is rarely used. We speculated that there could be a role for this measurement in predicting the need for neonatal exchange transfusion. Read More

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February 2021

Using ROPScore and CHOP ROP for early prediction of retinopathy of prematurity in a Chinese population.

Ital J Pediatr 2021 Feb 18;47(1):39. Epub 2021 Feb 18.

Department of Neonatology, Children's Hospital of Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, 33 Longhuwaihuan Road, Zhengzhou, 450018, China.

Purpose: Retinopathy of prematurity (ROP) is a disease that causes vision loss, vision impairment, and blindness, most frequently manifesting among preterm infants. ROPScore and CHOP ROP (Children's Hospital of Philadelphia ROP) are similar scoring models to predict ROP using risk factors such as postnatal weight gain, birth weight (BW), and gestation age (GA). The purpose of this study was to compare the accuracy and difference between using ROPScore and CHOP ROP for the early prediction of ROP. Read More

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February 2021

Natural history of pulmonary atresia with intact ventricular septum (PAIVS) and critical pulmonary stenosis (CPS) and prediction of outcome.

Arch Gynecol Obstet 2021 Feb 14. Epub 2021 Feb 14.

Division of Prenatal Medicine, Department of Obstetrics and Gynecology, Justus-Liebig-University Giessen and University Hospital Giessen & Marburg, Giessen, Germany.

Objectives: To analyse prenatal parameters predicting biventricular (BV) outcome in pulmonary atresia with intact ventricular septum/critical pulmonary stenosis (PAIVS/CPS).

Methods: We evaluated 82 foetuses from 01/08 to 10/18 in 3 centres in intervals 1 (< 24 weeks), 2 (24-30 weeks) and 3 (> 30 weeks).

Results: 61/82 (74. Read More

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February 2021

Relations of Maternal Depression and Parenting Self-Efficacy to the Self-Regulation of Infants in Low-Income Homes.

J Child Fam Stud 2020 Aug 25;29(8):2330-2341. Epub 2020 Jun 25.

The Ohio State University Crane Center for Early Childhood Research and Policy.

There is increasing recognition that young children's self-regulation provides a foundation for overall wellness later in life. Yet, infants reared in poverty may exhibit less-developed self-regulation compared to their more advantaged peers. Factors associated with poverty that may influence early self-regulation include maternal depression and parenting self-efficacy. Read More

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Physiologically Based Pharmacokinetic Modeling Framework to Predict Neonatal Pharmacokinetics of Transplacentally Acquired Emtricitabine, Dolutegravir, and Raltegravir.

Clin Pharmacokinet 2021 Feb 2. Epub 2021 Feb 2.

Bayer AG, Clinical Pharmacometrics, Leverkusen, Germany.

Background And Objective: Little is understood about neonatal pharmacokinetics immediately after delivery and during the first days of life following intrauterine exposure to maternal medications. Our objective was to develop and evaluate a novel, physiologically based pharmacokinetic modeling workflow for predicting perinatal and postnatal disposition of commonly used antiretroviral drugs administered prenatally to pregnant women living with human immunodeficiency virus.

Methods: Using previously published, maternal-fetal, physiologically based pharmacokinetic models for emtricitabine, dolutegravir, and raltegravir built with PK-Sim/MoBi, placental drug transfer was predicted in late pregnancy. Read More

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February 2021

Error simulation modeling to assess the effects of bias and precision on bilirubin measurements used to screen for neonatal hyperbilirubinemia.

Clin Chem Lab Med 2021 May 20;59(6):1069-1075. Epub 2021 Jan 20.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.

Objectives: Error simulation models have been used to understand the relationship between analytical performance and clinical outcomes. We developed an error simulation model to understand the effects of method bias and precision on misclassification rate for neonatal hyperbilirubinemia using an age-adjusted risk assessment tool.

Methods: For each of 176 measured total bilirubin (TSB) values, 10,000 simulated total bilirubin (TB) values were generated at each combination of bias and precision conditions for coefficient of variation (CV) between 1 and 15%, and for biases between -51. Read More

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Efficacy of the WINROP algorithm for retinopathy of prematurity screening in Southern China.

Int J Ophthalmol 2021 18;14(1):127-132. Epub 2021 Jan 18.

Department of Ophthalmology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, Guangdong Province, China.

Aim: To evaluate the predicting efficacy of severe retinopathy of prematurity (ROP) by the WINROP algorithm (http://winrop.com) in Southern China.

Methods: All preterm infants with the gestational age (GA) less than 32wk were included. Read More

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January 2021

Late gestation predictors of a postnatal biventricular circulation after fetal aortic valvuloplasty.

Prenat Diagn 2021 Mar 2;41(4):479-485. Epub 2021 Feb 2.

Department of Cardiology, Boston Children's Hospital, Boston, Massachusetts, USA.

Objectives: Fetal aortic valvuloplasty (FAV) for severe aortic stenosis (AS) has shown promise in averting progression to hypoplastic left heart syndrome. After FAV, predicting which fetuses will achieve a biventricular (BiV) circulation after birth remains challenging. Identifying predictors of postnatal circulation on late gestation echocardiography will improve parental counseling. Read More

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Biphasic Postnatal Umbilical Cord Shortening.

Pediatr Dev Pathol 2021 Mar-Apr;24(2):116-120. Epub 2021 Jan 13.

Department of Mathematics and Statistics, University of South Alabama, Mobile, Alabama.

Introduction: Variations in postnatal length of refrigerated, unfixed umbilical cords were studied over time to elucidate natural changes and times of stability.

Methods: Length was measured in 132 cords following severance, repeated at varying timed intervals and studied by analysis of variance and regression analysis.

Results: Data show immediate rapid initial phase shortening (mean 4. Read More

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January 2021

An investigation of systemic exposure to bisphenol AF during critical periods of development in the rat.

Toxicol Appl Pharmacol 2021 01 15;411:115369. Epub 2020 Dec 15.

Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.

Due to structural similarity to bisphenol A and lack of safety data, the National Toxicology Program (NTP) is evaluating the potential toxicity of bisphenol AF (BPAF) in rodent models. The current investigation reports the internal exposure data for free (unconjugated BPAF) and total (free and conjugated forms) BPAF during critical stages of development following perinatal dietary exposure in Hsd:Sprague Dawley®SD® rats to 0 (vehicle control), 338, 1125, and 3750 ppm BPAF from gestation day (GD) 6 to postnatal day (PND) 28. Free and total BPAF concentrations in maternal plasma at GD 18, PND 4, and PND 28 increased with the exposure concentration; free BPAF concentrations were ≤ 1. Read More

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January 2021

Evaluation of Extrauterine Head Growth From 14-21 days to Discharge With Longitudinal Intergrowth-21st Charts: A New Approach to Identify Very Preterm Infants at Risk of Long-Term Neurodevelopmental Impairment.

Front Pediatr 2020 19;8:572930. Epub 2020 Nov 19.

Neonatal Care Unit, Department of Public Health and Pediatric Sciences, University of Turin, Turin, Italy.

ExtraUterine Growth Restriction (EUGR) is a common definition for in-hospital growth failure of very preterm infants. Wide heterogeneity is found in definitions and anthropometric charts used to describe EUGR. We aim to compare two traditional definitions of EUGR with a newly proposed one, based on a longitudinal evaluation, that takes into account the physiological period of fluid loss after birth. Read More

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November 2020

Predicting Long-Term Respiratory Outcomes in Premature Infants: Is It Time to Move beyond Bronchopulmonary Dysplasia?

Children (Basel) 2020 Dec 10;7(12). Epub 2020 Dec 10.

Division of Neonatology, Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA.

Premature birth has been shown to be associated with adverse respiratory health in children and adults; children diagnosed with bronchopulmonary dysplasia (BPD) in infancy are at particularly high risk. Since its first description by Northway et al. about half a century ago, the definition of BPD has gone through several iterations reflecting the changes in the patient population, advancements in knowledge of lung development and injury, and improvements in perinatal care practices. Read More

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December 2020

Multi-Regression based supervised sample selection for predicting baby connectome evolution trajectory from neonatal timepoint.

Med Image Anal 2021 02 17;68:101853. Epub 2020 Oct 17.

BASIRA lab, Faculty of Computer and Informatics, Istanbul Technical University, Istanbul, Turkey; School of Science and Engineering, Computing, University of Dundee, UK. Electronic address:

The connectional map of the baby brain undergoes dramatic changes over the first year of postnatal development, which makes its mapping a challenging task, let alone learning how to predict its evolution. Currently, learning models for predicting brain connectomic developmental trajectories remain broadly absent despite their great potential in spotting atypical neurodevelopmental disorders early. This is most likely due to the scarcity and often incompleteness of longitudinal infant neuroimaging studies for training such models. Read More

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February 2021

Congenital diaphragmatic hernia.

Pediatr Radiol 2020 12 30;50(13):1855-1871. Epub 2020 Nov 30.

E. B. Singleton Department of Radiology, Texas Children's Hospital, Baylor College of Medicine, 6701 Fannin St., Suite 470, Houston, TX, 77030, USA.

Congenital diaphragmatic hernia (CDH) is a potentially severe anomaly that should be referred to a fetal care center with expertise in multidisciplinary evaluation and management. The pediatric radiologist plays an important role in the evaluation of CDH, both in terms of anatomical description of the anomaly and in providing detailed prognostic information for use in caring for the fetus and pregnant mother as well as planning for delivery and postnatal care. This article reviews the types of hernias, including distinguishing features and imaging clues. Read More

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December 2020

Meconium proteases and antiproteases as a potential source of biomarkers for the assessment of the intrauterine environment of the fetus.

J Matern Fetal Neonatal Med 2020 Nov 18:1-7. Epub 2020 Nov 18.

Department of Biochemistry and Clinical Chemistry, Medical University of Warsaw, Warsaw, Poland.

Background: A protease-antiprotease balance is required to maintain the homeostasis of the intrauterine environment in which the fetus develops. Proteases and antiproteases accumulate in meconium exclusively during intrauterine life and are excreted after birth.

Methods: Proteomic analysis was used to investigate the protein composition in pooled 50 serial meconium portions from 10 neonates. Read More

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November 2020

Juvenile stress facilitates safety learning in male and female high alcohol preferring mice.

Behav Brain Res 2021 02 6;400:113006. Epub 2020 Nov 6.

Department of Psychological Sciences, Purdue University, West Lafayette, IN, USA; Purdue Institute for Integrative Neuroscience, Purdue University, West Lafayette, IN, USA. Electronic address:

Adversities during juvenility increase the risk for stress-related disorders, such as post-traumatic stress disorder (PTSD) and alcohol use disorder. However, stress can also induce coping mechanisms beneficial for later stressful experiences. We reported previously that mice selectively bred for high alcohol preference (HAP) exposed to stress during adolescence (but not during adulthood) showed enhanced fear-conditioned responses in adulthood, as measured by fear-potentiated startle (FPS). Read More

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February 2021

Exploring the predicted yield of prenatal testing by evaluating a postnatal population with structural abnormalities using a novel mathematical model.

Prenat Diagn 2021 Feb 4;41(3):354-361. Epub 2020 Nov 4.

The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, Texas, USA.

Objective: To determine the yield of prenatal testing and screening options after identification of fetal structural abnormalities using a novel mathematical model.

Method: A retrospective chart review was conducted to collect structural abnormality and genetic testing data on infants who were evaluated postnatally by a medical geneticist. A novel mathematical model was used to determine and compare the predicted diagnostic yields of prenatal testing and screening options. Read More

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February 2021

Maternal exposure to childhood traumatic events, but not multi-domain psychosocial stressors, predict placental corticotrophin releasing hormone across pregnancy.

Soc Sci Med 2020 12 17;266:113461. Epub 2020 Oct 17.

Departments of Psychiatry and Pediatrics, University of California San Francisco, USA.

Maternal psychosocial stress increases the risk of adverse birth and postnatal outcomes for the mother and child, but the role of maternal exposure to childhood traumatic events (CTE) and multi-domain psychosocial stressors for the level and rise of placental Corticotrophin-Releasing Hormone (pCRH) across pregnancy has been understudied. In a sociodemographically and racially diverse sample of 1303 women (64% Black, 36% White/others) with low-medical risk pregnancies at enrollment from Shelby County, Tennessee, USA, blood samples were drawn twice, corresponding roughly to second and third trimester, and extracted prior to conducting radioimmune assays for pCRH. Mothers reported CTE (physical abuse, sexual abuse, or family violence, in childhood), adulthood traumatic events, and interpersonal violence during pregnancy. Read More

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December 2020

Reduced Intellectual Ability in Offspring Born from Preeclamptic Mothers: A Prospective Cohort Study.

Risk Manag Healthc Policy 2020 8;13:2037-2046. Epub 2020 Oct 8.

Department of Gynecology and Obstetrics, Fuzhou First Hospital Affiliated to Fujian Medical University, Fuzhou 350004, People's Republic of China.

Background: Severe preeclampsia may affect placental development, and high homocysteine (Hcy) levels are linked to intellectual disability. However, the correlation between perinatal Hcy levels and intellectual ability remains unknown in severe preeclampsia-affected offspring.

Objective: We aimed to investigate the intellectual ability in offspring born from preeclamptic mothers and examine the role of prenatal Hcy in the prediction of intellectual disability in preschool-aged offspring. Read More

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October 2020

Consistency of EEG asymmetry patterns in infants of depressed mothers.

Dev Psychobiol 2020 Oct 16. Epub 2020 Oct 16.

Department of Psychology, Emory University, Atlanta, GA, USA.

We evaluated frontal electroencephalogram (EEG) asymmetry across multiple contexts as an index of a general affective response predisposition in 12-month-old infants whose mothers were at elevated risk for perinatal depression due to their mother's history of depression. We further examined mothers' prenatal, postnatal, and concurrent depressive symptom levels in relation to infants' frontal EEG asymmetry consistency. Mothers (n = 132) with a history of depression prior to pregnancy completed depressive symptom scales repeatedly during pregnancy and the first year postpartum. Read More

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October 2020

It Is Complex: Predicting Gastroschisis Outcomes Using Prenatal Imaging.

J Surg Res 2021 02 10;258:381-388. Epub 2020 Oct 10.

Section of Pediatric Surgery, Riley Hospital for Children, Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana. Electronic address:

Background: Gastroschisis occurs in one of 2000 births with survival rates partially contingent on intestinal complications and time to establishing feeding. Enhancements in prenatal imaging have given better insight into postnatal outcomes. The goal of this study was to examine the gastroschisis patient population at a single children's hospital in the modern era and to use prenatal ultrasound (US) to develop new prenatal prognostic indicators. Read More

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February 2021

'Postnatal growth during the first five years of life in SGA and AGA neonates with reduced fetal growth'.

Early Hum Dev 2020 12 23;151:105199. Epub 2020 Sep 23.

Department of Obstetrics & Gynaecology, GROW School of Oncology and Developmental Biology, Maastricht University Medical Centre (MUMC+), Maastricht, the Netherlands.

Background: Even though a lot of research has been done on postnatal growth and the occurrence of catch-up growth in small-for-gestational age (SGA) neonates, this phenomenon has not been studied well in appropriate-for-gestational age (AGA) neonates. Postnatal catch-up growth may also occur in AGA neonates indicating a compensatory mechanism for undiagnosed intrauterine growth restriction, especially in AGA neonates with reduced fetal growth velocity.

Aims: To describe postnatal growth during the first 5 years of life in SGA and AGA neonates and evaluating the role of fetal growth velocity in catch-up growth. Read More

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December 2020