713,313 results match your criteria pre- postsurgical

Impact of Preoperative Opioid Use on Patient-Reported Outcomes after Revision Total Knee Arthroplasty: A Propensity Matched Analysis.

J Knee Surg 2021 May 15. Epub 2021 May 15.

Department of Orthopaedic Surgery, Bioengineering Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

This is a retrospective study. Prior studies have characterized the deleterious effects of narcotic use in patients undergoing primary total knee arthroplasty (TKA). While there is an increasing revision arthroplasty burden, data on the effect of narcotic use in the revision surgery setting remain limited. Read More

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Recovering chemical sludge from the zero liquid discharge system of flue gas desulfurization wastewater as flame retardants by a stepwise precipitation process.

J Hazard Mater 2021 May 7;417:126054. Epub 2021 May 7.

Shanghai Engineering Research Center of Energy - Saving in Heat Exchange Systems, College of Environmental and Chemical Engineering, Shanghai University of Electric Power, Shanghai 200090, China.

In this study, a five-stage stepwise precipitation process, including pre-sedimentation, magnesium removal, gypsum precipitation, ettringite precipitation and calcium removal, was proposed as a softening pretreatment for zero liquid discharge system for flue gas desulfurization wastewater. Batch tests and long-term bench-scale experiment showed that magnesium, sulfate and calcium were efficiently removed with efficiencies all above 98.0%, leaving a clean effluent majorly containing NaCl and NaOH. Read More

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Pre-registration nursing and occupational therapy students' experience of interprofessional simulation training designed to develop communication and team-work skills: A mixed methods study.

Nurse Educ Pract 2021 May 3;53:103073. Epub 2021 May 3.

Centre for Quality and Patient Safety Research, Institute of Health Transformation, School of Nursing and Midwifery, Deakin University, Geelong, VIC 3228, Australia. Electronic address:

To bridge the gap between university and the clinical environment, the university where this study was conducted incorporated interprofessional simulation sessions into the curricula for pre-registration nursing and occupational therapy students. The purpose of the study was to evaluate the effectiveness of simulation training to support the development of students' interprofessional communication and teamwork skills. Study participants were first-year students. Read More

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Multidisciplinary treatment strategy for locally advanced gastric cancer: A systematic review.

Surg Oncol 2021 May 11;38:101599. Epub 2021 May 11.

Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Background: Multidisciplinary management of patients with locally advanced gastric cancer (LAGC) remains unstandardized worldwide. We performed a systemic review to summarize the advancements, regional differences, and current recommended multidisciplinary treatment strategies for LAGC.

Methods: Eligible studies were identified through a comprehensive search of PubMed, Web of Science, Cochrane Library databases and Embase. Read More

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Immobilization of cadmium and lead using phosphorus-rich animal-derived and iron-modified plant-derived biochars under dynamic redox conditions in a paddy soil.

Environ Int 2021 May 12;156:106628. Epub 2021 May 12.

University of Wuppertal, School of Architecture and Civil Engineering, Institute of Foundation Engineering, Water- and Waste-Management, Laboratory of Soil- and Groundwater-Management, Pauluskirchstraße 7, 42285 Wuppertal, Germany; University of Sejong, Department of Environment, Energy and Geoinformatics, Guangjin-Gu, Seoul 05006, Republic of Korea. Electronic address:

Functionalized biochar has gained extensive interests as a sustainable amendment for an effective remediation of paddy soils contaminated with heavy metals (HMs). We examined the efficiency of pig carcass-derived biochar (P-rich biochar, total P = 8.3%) and pristine (raw biochar, total Fe = 0. Read More

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Assessment of the ANDE 6C Rapid DNA system and investigative biochip for the processing of calcified and muscle tissue.

Forensic Sci Int Genet 2021 May 7;53:102526. Epub 2021 May 7.

DNA Support Unit, Federal Bureau of Investigation Laboratory, 2501 Investigation Parkway, Quantico, VA 22135, USA. Electronic address:

The ANDE 6C Rapid DNA system could offer a potential alternative for the processing of calcified and soft tissue samples, often encountered in mass disaster scenarios. While originally designed for single source buccal swabs, interest in the performance of these instruments when using other types of single source samples continues to grow. To enhance the recovery of otherwise lesser quality samples, the manufacturer developed the investigative biochip, an alternative to the NDIS approved Arrestee biochip for reference sample buccal swabs. Read More

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Functional performance tests in interstitial lung disease: Impairment and measurement properties.

Respir Med 2021 Apr 28;184:106413. Epub 2021 Apr 28.

Laboratory of Research in Respiratory Physiotherapy (LFIP), Department of Physiotherapy, State University of Londrina, Londrina, Brazil; Department of Rehabilitation Sciences, University Pitágoras UNOPAR, Londrina, Brazil. Electronic address:

Background: There is limited information regarding impairment in functional performance tests and their measurement properties in ILD. The present study aimed to verify the impairment and measurement properties of functional performance tests in ILD.

Methods: ILD and healthy individuals underwent assessments of pulmonary function, peripheral muscle strength (handgrip force and maximum isometric contraction of quadriceps femoris - MIVCq) and exercise capacity (6-min walk test - 6MWT). Read More

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Predictive processing, cognitive control, and tonality stability of music: An fMRI study of chromatic harmony.

Brain Cogn 2021 May 12;151:105751. Epub 2021 May 12.

Graduate Institute of Musicology, National Taiwan University, Taipei, Taiwan; Neurobiology and Cognitive Science Center, National Taiwan University, Taipei, Taiwan. Electronic address:

The present study aimed at identifying the brain regions which preferentially responded to music with medium degrees of key stability. There were three types of auditory stimuli. Diatonic music based strictly on major and minor scales has the highest key stability, whereas atonal music has the lowest key stability. Read More

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Functions of the GABAergic system on serum LH concentrations in pre-pubertal Nellore heifers.

Anim Reprod Sci 2021 May 12;229:106764. Epub 2021 May 12.

Department of Animal Production and Health, Sao Paulo State University, Aracatuba, Brazil. Electronic address:

This study was conducted to evaluate the luteinizing hormone (LH) secretion pattern after gamma-aminobutyric acid (GABA) antagonist to determine the effects of the GABAergic system on LH secretion during reproductive maturation in pre-pubertal Nellore heifers. Nellore heifers (n = 10) were administered a picrotoxin injection of 0.18 mg/kg, i. Read More

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Ammonia nitrogen removal from coking wastewater and high quality gypsum recovery by struvite recycling by using calcium hydroxide as decomposer.

J Environ Manage 2021 May 12;292:112712. Epub 2021 May 12.

School of Environment and Civil Engineering, Dongguan University of Technology, Dongguan, 523808, China.

This study deals with the highly significant and cost-effective pretreatment of the high concentration of the Total Ammonia Nitrogen (TAN) in coking wastewater to improve the biodegradability. Struvite crystallization is a promising process for TAN removal, but the high operating cost hinders its application. To solve this problem, a novel struvite recycling process was proposed for pre-treating TAN present in the coking wastewater, within which struvite was decomposed in the solid-liquid system using Ca(OH) as the decomposer. Read More

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Even Mists Have Silver Linings: Promoting LGBTQ+ Acceptance and Solidarity through Community-Based Theatre in India.

Public Health 2021 May 12;194:252-259. Epub 2021 May 12.

Department of Community Health and Epidemiology, University of Saskatchewan, Canada.

Objectives: This project aimed to assess the effectiveness of a community-based theatre intervention to improve attitudes towards and increase knowledge about LGBTQ+ communities among audiences in Mumbai, India.

Study Design: This study was a program evaluation using pre- and post-show surveys that incorporated an adapted version of The Riddle Scale: Attitudes Towards Difference and questions assessing self-reported knowledge about LGBTQ+-related issues to assess changes in attitudes and knowledge after viewing the theatre intervention.

Methods: An original 90-min devised play was created by a company of Indian, American, and Canadian theatre artists using Participatory Action Research methods and was designed to bring audiences to a deeper understanding of LGBTQ+ identity. Read More

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Preoperative non-palpable breast lesion localization, innovative techniques and clinical outcomes in surgical practice: A systematic review and meta-analysis.

Breast 2021 Apr 22;58:93-105. Epub 2021 Apr 22.

Breast Surgery Unit, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy.

Pre-operative localization of non-palpable breast lesions with non-wired non-ionizing (NWNI) techniques may improve clinical outcomes as reoperation rate, cosmetic outcome and contribute to organizational aspects improvement in breast-conserving surgery (BCS). However only limited literature is available and clinical studies involving these forefront devices are often small and non-randomized. Furthermore, there is a lack of consensus on free margins and cosmetic outcomes definitions. Read More

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Pre-saccadic attention spreads to stimuli forming a perceptual group with the saccade target.

Cortex 2021 Apr 15;140:179-198. Epub 2021 Apr 15.

Berlin School of Mind and Brain, Humboldt-Universität zu Berlin, Germany; Department of Psychology, Humboldt-Universität zu Berlin, Germany; Exzellenzcluster Science of Intelligence, Technische Universität Berlin, Berlin, Germany.

The pre-saccadic attention shift-a rapid increase in visual sensitivity at the target-is an inevitable precursor of saccadic eye movements. Saccade targets are often parts of the objects that are of interest to the active observer. Although the link between saccades and covert attention shifts is well established, it remains unclear if pre-saccadic attention selects the location of the eye movement target or rather the entire object that occupies this location. Read More

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Clinical Outcomes and Safety of Mechanical Thrombectomy for Acute Ischaemic Stroke in Patients with Pre-Existing Dependency.

J Stroke Cerebrovasc Dis 2021 May 12;30(7):105848. Epub 2021 May 12.

Univ. Lille, Inserm U1172, CHU Lille, Department of Neurology, Stroke unit, France.

Objectives: Pre-stroke dependency (PSD) is associated with poor outcome after stroke. The aim of the study was to evaluate the clinical outcomes and safety of mechanical thrombectomy (MT) in pre-stroke dependent patients compared to pre-stroke independent patients.

Material And Methods: We included consecutive patients with anterior circulation acute ischaemic stroke related to large vessel occlusion (AIS-LVO), treated by MT between January 1 2015 and July 1 2018 in our single comprehensive stroke center. Read More

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Tropical cyclone effects on water and sediment chemistry and the microbial community in estuarine ecosystems.

Environ Pollut 2021 May 5;286:117228. Epub 2021 May 5.

Department of Civil and Environmental Engineering, Princeton University, Princeton, NJ, 08544, USA. Electronic address:

Frequent and intense storm disturbances can have widespread and strong effects on the nitrogen and iron cycles and their associated microbial communities in estuary systems. A three-year investigation was conducted in the Pearl River and Zhanjiang estuaries in Guangdong Province, China through repeated sampling at three timepoints, defined as pre-storm (<1 month before storm), post-storm (<1 month after storm), and non-storm (6-8 months after storm). Increased nutrient concentrations (total organic carbon, nitrate, nitrite, ammonium, and sulfate) in both the sediment and water column were observed immediately after storm. Read More

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Pre-transplant red blood cell and platelet transfusion burden in de novo myelodysplastic syndrome undergoing allogeneic transplantation: Pre-transplant red blood cell and platelet transfusion burden in de novo MDS after allogeneic transplantation.

Transplant Cell Ther 2021 May 12. Epub 2021 May 12.

Japanese Data Center for Hematopoietic Cell Transplantation, Nagoya, Japan; Department of Healthcare Administration, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Background: Most patients of myelodysplastic syndrome (MDS) require red blood cell (RBC) and/or platelet transfusion during their disease courses, which could cause an increased risk of iron overload and alloimmunization. However, it remains less clear whether pre-transplant RBC or platelet transfusion burden affects transplant outcomes in patients with MDS.

Objective: The objective was to examine the significance of pre-transplant RBC and platelet transfusion burden on transplant outcomes after allogeneic HCT for adults with de novo MDS. Read More

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Perinatal Outcomes in Twin Pregnancies Complicated by Gestational Diabetes.

Am J Obstet Gynecol MFM 2021 May 12:100396. Epub 2021 May 12.

Department of Obstetrics, Gynecology, and Reproductive Sciences, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania; Magee-Womens Research Institute, Pittsburgh, Pennsylvania. Electronic address:

Background: Gestational diabetes in singleton pregnancies increases the risk of large for gestational age infants, hypertensive disorders of pregnancy, and neonatal morbidity.[1,2,3,4] Compared to singleton gestations, twin gestations are at increased risk for fetal growth abnormalities, hypertensive disorders and neonatal morbidity.[5] Whether gestational diabetes further increases the risk of these outcomes is unclear. Read More

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LayNii: A software suite for layer-fMRI.

Neuroimage 2021 May 12:118091. Epub 2021 May 12.

Brain Innovation, Maastricht, Netherlands.

High-resolution fMRI in the sub-millimeter regime allows researchers to resolve brain activity across cortical layers and columns non-invasively. While these high-resolution data make it possible to address novel questions of directional information flow within and across brain circuits, the corresponding data analyses are challenged by MRI artifacts, including image blurring, image distortions, low SNR, and restricted coverage. These challenges often result in insufficient spatial accuracy of conventional analysis pipelines. Read More

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Diagnostic accuracy of elastography and magnetic resonance imaging in patients with NAFLD: a systematic review and meta-analysis.

J Hepatol 2021 May 12. Epub 2021 May 12.

Oxford Centre for Clinical Magnetic Resonance Research, Radcliffe Department of Medicine, University of Oxford, Oxford, UK; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust and the University of Oxford, Oxford, UK. Electronic address:

Background And Aims: Vibration-controlled transient elastography (VCTE), point shear wave elastography (pSWE), two-dimensional shear wave elastography (2DSWE), magnetic resonance elastography (MRE), and magnetic resonance imaging (MRI) are proposed as non-invasive tests for patients with non-alcoholic fatty liver disease (NAFLD). This study evaluated their diagnostic accuracy for liver fibrosis and non-alcoholic steatohepatitis (NASH).

Methods: PubMED/MEDLINE, EMBASE and the Cochrane Library were searched for studies examining the diagnostic accuracy of these index tests against histology as the reference standard, in adult patients with NAFLD. Read More

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Effect of thoracic spinal cord injury on forelimb somatosensory evoked potential.

Brain Res Bull 2021 May 12. Epub 2021 May 12.

Department of Electrical Engineering, College of Engineering, American University of Sharjah, ESB-2018, Engineering Science Building, American University of Sharjah, University City, Sharjah, 26666, United Arab Emirate. Electronic address:

In this paper, we investigate the forelimbs somatosensory evoked potential (SSEP) signals, which are representative of the integrity of ascending sensory pathways and their stability as well as function, recorded from corresponding cortices, post thoracic spinal cord injury (SCI). We designed a series of distinctive transection SCI to investigate whether forelimbs SSEPs change after right T10 hemi-transection, T8 and T10 double hemi-transection and T8 complete transection in rat model of SCI. We used electrical stimuli to stimulate median nerves and recorded SSEPs from left and right somatosensory areas of both cortices. Read More

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Deep Learning Applied to Electroencephalogram Data in Mental Disorders: A systematic Review.

Biol Psychol 2021 May 12:108117. Epub 2021 May 12.

Department for Psychiatry, Psychotherapy and Psychosomatics, Psychiatric University Hospital Zurich (PUK), Switzerland; University Hospital Zurich, Switzerland; University Zurich, Switzerland. Electronic address:

In recent medical research, tremendous progress has been made in the application of deep learning (DL) techniques. This article systematically reviews how DL techniques have been applied to electroencephalogram (EEG) data for diagnostic and predictive purposes in conducting research on mental disorders. EEG-studies on psychiatric diseases based on the ICD-10 or DSM-V classification that used either convolutional neural networks (CNNs) or long -short-term-memory (LSTMs) networks for classification were searched and examined for the quality of the information they contained in three domains: clinical, EEG-data processing, and deep learning. Read More

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Structure-guided design of ultrapotent disruptive IgE inhibitors to rapidly terminate acute allergic reactions.

J Allergy Clin Immunol 2021 May 12. Epub 2021 May 12.

Department of Structural Biology, Stanford University School of Medicine, Stanford California 94305; Progam in Immunology, Stanford University School of Medicine, Stanford California 94305; Sean N. Parker Center for Allergy Research at Stanford University. Electronic address:

Background: Anaphylaxis represents one of the most severe and fatal forms of allergic reactions. Like most other allergies, it is caused upon activation of basophils and mast cells by allergen-mediated cross-linking of immunoglobulin E (IgE) bound to its high affinity receptor FcεRI on the cell surface. The systemic release of soluble mediators induces an inflammatory cascade rapidly causing symptoms with peak severity in minutes to hours after allergen exposure. Read More

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Association between a pre-admission limitation in walking ability and post-discharge adverse outcomes among hospitalized patients with heart failure: Report from a multicenter prospective cohort study.

Int J Cardiol 2021 May 12. Epub 2021 May 12.

Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan. Electronic address:

Background Although limited walking ability at discharge is a known risk factor for adverse outcomes in older patients with heart failure (HF), the association between pre-admission limitations and adverse outcomes is unknown. Therefore, we evaluated the prevalence of a pre-admission limitation in walking ability and its relationship with post-discharge outcomes among patients with HF with reduced, mid-range, and preserved left-ventricular ejection fraction (HFrEF, HFmrEF, and HFpEF). Methods We followed 2042 patients aged ≥65 years (HFrEF, n = 668; HFmrEF, n = 360; HFpEF, n = 1014) from a multicenter cohort study in Japan. Read More

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Delivery of oxaliplatin to colorectal cancer cells by folate-targeted UiO-66-NH.

Toxicol Appl Pharmacol 2021 May 12:115573. Epub 2021 May 12.

Department of Medical Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran; Metabolic syndrome Research center, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address:

Oxaliplatin is being used in different malignancies and several side effects are reported for patients taking Oxaliplatin, including peripheral neuropathy, nausea and vomiting, diarrhea, mouth sores, low blood counts, fatigue, loss of appetite, etc. Here we have developed a targeted anticancer drug delivery system based on folate-conjugated amine-functionalized UiO-66 for the delivery of oxaliplatin (OX). UiO-66-NH (U) and UiO-66-NH-FA(FU) were pre-functionalized by the incorporation of folic acid (FA) into the structure via coordination of the carboxylate group of FA. Read More

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Descemet membrane endothelial keratoplasty (DMEK) in eyes with chronic ocular hypotony following glaucoma surgery.

Am J Ophthalmol 2021 May 12. Epub 2021 May 12.

Department of Ophthalmology, Rabin Medical Center, Petach Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Medica medical center, Tel Aviv, Israel.

Purpose: To assess the outcomes of Descemet membrane endothelial keratoplasty (DMEK) in patients with ocular hypotony following glaucoma surgery.

Design: retrospective case series.

Methods: SETTING: Multicenter retrospective case series. Read More

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Effect of whole-body vibration after a resistance exercise bout on heart rate variability in hypertensive population.

J Complement Integr Med 2021 May 17. Epub 2021 May 17.

Centre for Physiotherapy and Rehabilitation Sciences, Jamia Millia Islamia (A Central University), New Delhi, India.

Objectives: To investigate the effect of whole-body vibration (WBV) in the recovery phase after resistance exercise (RE) bout on heart rate variability (HRV) and blood pressure (BP) in a hypertensive population.

Methods: Twenty hypertensive males and females were randomly allocated into group A (RE bout), and group B (RE bout with WBV). Pre-test and post-test measure of HRV, systolic blood pressure, and diastolic blood pressure were taken before and after RE and placebo WBV in one group and in another group of RE with WBV in the recovery phase. Read More

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The use of statistical modelling to identify important parameters for the shape of the torso following surgery for adolescent idiopathic scoliosis.

J Anat 2021 May 15. Epub 2021 May 15.

Institute of Clinical Science, University of Birmingham, Birmingham, UK.

The surgical strategy in adolescent idiopathic scoliosis (AIS) aims to recreate the symmetry of the torso. This requires the minimisation of both the size of the scoliosis and the angulation between the sides of the torso, along with the recreation of a normal thoracic kyphosis. This study uses predictive modelling to identify the significance of the value of the pre-operative parameters, and the change in the magnitude of the parameters as a result of an operation on the shape of the torso using the 'most prominent points'; two areas of maximum prominence on either side of the spine with x, y and z coordinates. Read More

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Incidence, characteristics and clinical profile of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in patients with pre-existing primary immune thrombocytopenia (ITP) in Spain.

Br J Haematol 2021 May 15. Epub 2021 May 15.

Hospital Universitario Virgen del Rocío, Sevilla, Spain.

Infections are one of the well-known precipitating factors for relapses in patients with immune thrombocytopenia (ITP). Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection can sometimes lead to or be associated with thrombocytopenia due to an increase in peripheral platelet destruction from inflammatory hyperactivation. Currently, we do not know if SARS-CoV-2 infection modifies the natural evolution of chronic or persistent ITP or if previous immunosuppression of patients with ITP influences the incidence and severity of coronavirus disease 2019 (COVID-19) in this group. Read More

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Do natural ingredients in a dentifrice contribute to prevention of plaque and gingivitis?

Int J Dent Hyg 2021 May 15. Epub 2021 May 15.

Department of Periodontology, Academic Centre for Dentistry Amsterdam (ACTA), Faculty of Dentistry, University of Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

Objective: To test the effectiveness of a dentifrice containing the turmeric and licorice extract compared to a control for preventing plaque and gingivitis over a four-month period.

Material And Methods: Ninety (non-dental) participants with moderate gingival inflammation(≥40%) were selected. The triple blind study consisted of two phases, namely at first a 3-week pre-experimental phase of using an oxygenating and chlorhexidine (CHX) mouthrinse. Read More

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Coronavirus Disease 2019 (COVID-19) Vaccines: A Concise Review.

Oral Dis 2021 May 15. Epub 2021 May 15.

Department of Preventive and Restorative Dentistry, College of Dental Medicine, University of Sharjah, UAE.

The development of a successful vaccine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the agent of coronavirus disease 2019 (COVID-19), in an unmatched period of ten months, is a tribute to human ingenuity in the face of a vicious pandemic. A return to pre-pandemic `normalcy` depends on the successful delivery of the vaccine to a majority (~70%) so as to develop herd immunity critical to arrest the community spread of infection. Vaccination against COVID-19 is particularly important for dentistry as the dental team works in an environment replete with aerosol-generating procedures (AGP) that facilitate virus spread. Read More

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