12,639 results match your criteria potentials detection

Spontaneous activity competes with externally evoked responses in sensory cortex.

Proc Natl Acad Sci U S A 2021 Jun;118(25)

Optophysiology Lab, Institute of Biology III, University of Freiburg, 79104 Freiburg, Germany;

The interaction between spontaneous and externally evoked neuronal activity is fundamental for a functional brain. Increasing evidence suggests that bursts of high-power oscillations in the 15- to 30-Hz beta-band represent activation of internally generated events and mask perception of external cues. Yet demonstration of the effect of beta-power modulation on perception in real time is missing, and little is known about the underlying mechanism. Read More

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Neurophysiological Correlates of Asymmetries in Vowel Perception: An English-French Cross-Linguistic Event-Related Potential Study.

Front Hum Neurosci 2021 3;15:607148. Epub 2021 Jun 3.

Department of Speech, Language, and Hearing Sciences, University of Florida, Gainesville, FL, United States.

Behavioral studies examining vowel perception in infancy indicate that, for many vowel contrasts, the ease of discrimination changes depending on the order of stimulus presentation, regardless of the language from which the contrast is drawn and the ambient language that infants have experienced. By adulthood, linguistic experience has altered vowel perception; analogous asymmetries are observed for non-native contrasts but are mitigated for native contrasts. Although these directional effects are well documented behaviorally, the brain mechanisms underlying them are poorly understood. Read More

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Detection without further processing or processing without automatic detection? Differential ERP responses to lexical-semantic processing in toddlers at high clinical risk for autism and language disorder.

Cortex 2021 May 27;141:465-481. Epub 2021 May 27.

Child Psychopathology Unit, Scientific Institute, IRCCS Eugenio Medea, Bosisio Parini, Lecco, Italy.

Delays in early expressive vocabulary can reflect a specific delay in language acquisition or more general impairments in social communication. The neural mechanisms underlying the (dis)ability to establish the first lexical-semantic representations remain relatively unknown. Here, we investigate the electrophysiological underpinnings of these mechanisms during the critical phase of lexical acquisition in two groups of 19-month-old toddlers at risk for neurodevelopmental disorders, i. Read More

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Online detection of movement during natural and self-initiated reach-and-grasp actions from EEG signals.

J Neural Eng 2021 Jun 15. Epub 2021 Jun 15.

Institute of Neural Engineering, Graz University of Technology, Stremayrgasse 16/IV, Graz, Steiermark, 8010, AUSTRIA.

Movement intention detection using electroencephalography (EEG) is a challenging but important component of brain-computer interfaces (BCIs) for people with motor disabilities. Objective​: The goal of this study is to exploit low-frequency time-domain EEG signals, concretely movement-related cortical potentials (MRCPs), to perform asynchronous online detection of movement. The experimental paradigm must be easily transferable to people without any residual upper-limb movement function. Read More

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lncRNA Profiles Enable Prognosis Prediction and Subtyping for Esophageal Squamous Cell Carcinoma.

Front Cell Dev Biol 2021 28;9:656554. Epub 2021 May 28.

Department of Clinical Laboratory, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.

Long non-coding RNAs (lncRNAs) have emerged as useful prognostic markers in many tumors. In this study, we investigated the potential application of lncRNA markers for the prognostic prediction of esophageal squamous cell carcinoma (ESCC). We identified ESCC-associated lncRNAs by comparing ESCC tissues with normal tissues. Read More

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Multi-Interactive Dual-Decoder for RGB-Thermal Salient Object Detection.

IEEE Trans Image Process 2021 18;30:5678-5691. Epub 2021 Jun 18.

RGB-thermal salient object detection (SOD) aims to segment the common prominent regions of visible image and corresponding thermal infrared image that we call it RGBT SOD. Existing methods don't fully explore and exploit the potentials of complementarity of different modalities and multi-type cues of image contents, which play a vital role in achieving accurate results. In this paper, we propose a multi-interactive dual-decoder to mine and model the multi-type interactions for accurate RGBT SOD. Read More

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The Neural Correlates of Effortful Cognitive Processing Deficits in Schizophrenia: An ERP Study.

Front Hum Neurosci 2021 28;15:664008. Epub 2021 May 28.

Department of Psychiatry, The Affiliated Wuxi Mental Health Center of Nanjing Medical University, Wuxi, China.

Individuals' information processing includes automatic and effortful processes and the latter require sustained concentration or attention and larger amounts of cognitive "capacity." Event-related potentials (ERPs) reflect all neural activities that are related to a certain stimulus. Investigating ERP characteristics of effortful cognitive processing in people with schizophrenia would be helpful in further understanding the neural mechanism of schizophrenia. Read More

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Glycinergic axonal inhibition subserves acute spatial sensitivity to sudden increases in sound intensity.

Elife 2021 Jun 14;10. Epub 2021 Jun 14.

University of Leuven, Leuven, Belgium.

Locomotion generates adventitious sounds which enable detection and localization of predators and prey. Such sounds contain brisk changes or transients in amplitude. We investigated the hypothesis that ill-understood temporal specializations in binaural circuits subserve lateralization of such sound transients, based on different time of arrival at the ears (interaural time differences, ITDs). Read More

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Cortical Responses to Vowel Sequences in Awake and Anesthetized States: A Human Intracranial Electrophysiology Study.

Cereb Cortex 2021 Jun 12. Epub 2021 Jun 12.

Department of Anesthesiology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.

Elucidating neural signatures of sensory processing across consciousness states is a major focus in neuroscience. Noninvasive human studies using the general anesthetic propofol reveal differential effects on auditory cortical activity, with a greater impact on nonprimary and auditory-related areas than primary auditory cortex. This study used intracranial electroencephalography to examine cortical responses to vowel sequences during induction of general anesthesia with propofol. Read More

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Heartbeat and somatosensory perception.

Neuroimage 2021 Jun 7;238:118247. Epub 2021 Jun 7.

Department of Neurology, Max Planck Institute for Human Cognitive and Brain Sciences, 04103 Leipzig, Germany; MindBrainBody Institute, Berlin School of Mind and Brain, Humboldt-Universität zu Berlin, 10099 Berlin, Germany; Center for Stroke Research Berlin (CSB), Charité - Universitätsmedizin Berlin, 10117 Berlin, Germany.

Our perception of the external world is influenced by internal bodily signals. For example, we recently showed that timing of stimulation along the cardiac cycle and spontaneous fluctuations of heartbeat-evoked potential (HEP) amplitudes influence somatosensory perception and the associated neural processing (Al et al., 2020). Read More

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Derived loss of signal complexity and plasticity in a genus of weakly electric fish.

J Exp Biol 2021 Jun 10. Epub 2021 Jun 10.

Department of Biology, University of Oklahoma, Norman, OK, 73019, USA.

Signal plasticity can maximize the usefulness of costly animal signals such as the electric organ discharges (EODs) of weakly electric fishes. Some species of the order Gymnotiformes rapidly alter their EOD amplitude and duration in response to circadian cues and social stimuli. How this plasticity is maintained across related species with different degrees of signal complexity is poorly understood. Read More

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Hydrothermal carbonisation of mechanically dewatered digested sewage sludge-Energy and nutrient recovery in centralised biogas plant.

Water Res 2021 May 25;201:117284. Epub 2021 May 25.

Faculty of Engineering and Natural Sciences, Tampere University, P.O.Box 541, 33104 Tampere University, Finland.

This study aimed to assess the role of hydrothermal carbonisation (HTC) in digestate processing in centralised biogas plants receiving dewatered sludge from regional wastewater treatment plants and producing biomethane and fertilisers. Chemically conditioned and mechanically dewatered sludge was used as such (total solids (TS) 25%) or as diluted (15% TS) with reject water in 30 min or 120 min HTC treatments at 210 °C, 230 °C or 250 °C, and the produced slurry was filtered to produce hydrochars and filtrates. The different hydrochars contributed to 20-55% of the original mass, 72-88% of the TS, 74-87% of the energy content, 71-92% of the carbon, above 86% of phosphorous and 38-64% of the nitrogen present in the original digestates. Read More

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Visual recognition is heralded by shifts in local field potential oscillations and inhibitory networks in primary visual cortex.

J Neurosci 2021 Jun 7. Epub 2021 Jun 7.

The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, US 02139

Learning to recognize and filter familiar, irrelevant sensory stimuli eases the computational burden on the cerebral cortex. Inhibition is a candidate mechanism in this filtration process, and oscillations in the cortical local field potential (LFP) serve as markers of the engagement of different inhibitory neurons. We show here that LFP oscillatory activity in visual cortex is profoundly altered as male and female mice learn to recognize an oriented grating stimulus-low frequency (∼15 Hz peak) power sharply increases while high frequency (∼65 Hz peak) power decreases. Read More

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Thiomers of Chitosan and Cellulose: Effective Biosorbents for Detection, Removal and Recovery of Metal Ions from Aqueous Medium.

Chem Rec 2021 Jun 7. Epub 2021 Jun 7.

Department of Chemical Engineering, University of New Brunswick, E3B 5A3, Fredericton, New Brunswick, Canada.

Removal of toxic metal ions using adsorbents is a well-known strategy for water treatment. While chitosan and cellulose can adsorb weakly some types of metals, incorporating thiols as metal chelating agents can improve their sorption behaviors significantly. Presented in this review are the various chemical modification strategies applicable for thiolation of chitosan and cellulose in the forms of mercaptans, xanthates and dithiocarbamates. Read More

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Defective involuntary attention to novelty in type 1 diabetes and impaired awareness of hypoglycaemia.

Diabetes Res Clin Pract 2021 Jun 4;177:108898. Epub 2021 Jun 4.

Department of Endocrinology and Nutrition, Hospital de Santa Creu i Sant Pau, Barcelona, Spain; Department of Medicine, Autonomous University of Barcelona, Barcelona, Spain; CIBER-Bioengineering, Biomaterials and Nanotechnology (CIBER-BBN), Instituto de Salud Carlos III, Madrid, Spain. Electronic address:

Aim: To determine if there are differences in terms of neurophysiology and neurocognitive functioning in a group of type 1 diabetes (T1D) patients regarding hypoglycaemia awareness.

Methods: 27 patients with T1D were classified according to Clarke score as having impaired awareness of hypoglycaemia (IAH; n = 11) or normal awareness to hypoglycaemia (NAH; n = 16). We measured several clinical and sociodemographic variables and cognitive performance using neuropsychological tests. Read More

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Quantitative proteomics characterization of cancer biomarkers and treatment.

Mol Ther Oncolytics 2021 Jun 20;21:255-263. Epub 2021 Apr 20.

National Engineering Laboratory for Deep Process of Rice and Byproducts, College of Food Science and Engineering, Central South University of Forestry and Technology, Changsha 410004, Hunan, China.

Cancer accounted for 16% of all death worldwide in 2018. Significant progress has been made in understanding tumor occurrence, progression, diagnosis, treatment, and prognosis at the molecular level. However, genomics changes cannot truly reflect the state of protein activity in the body due to the poor correlation between genes and proteins. Read More

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Potentials of MicroRNA in Early Detection of Ovarian Cancer by Analytical Electrical Biosensors.

Crit Rev Anal Chem 2021 Jun 7:1-13. Epub 2021 Jun 7.

Institute of Microengineering and Nanoelectronics, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia.

The importance of nanotechnology in medical applications especially with biomedical sensing devices is undoubted. Several medical diagnostics have been developed by taking the advantage of nanomaterials, especially with electrical biosensors. Biosensors have been predominantly used for the quantification of different clinical biomarkers toward detection, screening, and follow-up the treatment. Read More

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Exploitation of optical and SAR amplitude imagery for landslide identification: a case study from Sikkim, Northeast India.

Environ Monit Assess 2021 Jun 5;193(7):386. Epub 2021 Jun 5.

G. B. Pant, National Institute of Himalayan Environment and Sustainable Development, Sikkim Regional Center, Gangtok (Sikkim), India.

Detection and mapping of landslides is one of the most important techniques used for reducing the impact of natural disasters especially in the Himalaya, owing to its high amount of tectonic deformation, seismicity, and unfavorable climatic conditions. Moreover, the northeastern part of the Himalaya, severely affected by landslides every monsoon, is poorly studied. The information on the inventories is inhomogeneous and lacking. Read More

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Neurophysiological evaluation of visual function in iRBD: potential role in stratifying RBD conversion risk.

Sleep Med 2021 May 15;84:26-31. Epub 2021 May 15.

Neurology and Stroke Unit, ASST Sette Laghi Ospedale di Circolo, Varese; DMC University of Insubria, Varese, Italy.

Study Objectives: To evaluate neurophysiological alterations of visual function in idiopathic REM sleep Behavior Disorder (iRBD) both as markers and predictors of neurodegenerative disorders.

Methods: In a longitudinal follow-up study of 46 consecutive iRBD patients (follow-up duration 8.4 ± 3. Read More

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The Amygdala Responds Rapidly to Flashes Linked to Direct Retinal Innervation: A Flash-evoked Potential Study Across Cortical and Subcortical Visual Pathways.

Neurosci Bull 2021 Jun 4. Epub 2021 Jun 4.

State Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, 650500, China.

Rapid detection and response to visual threats are critical for survival in animals. The amygdala (AMY) is hypothesized to be involved in this process, but how it interacts with the visual system to do this remains unclear. By recording flash-evoked potentials simultaneously from the superior colliculus (SC), lateral posterior nucleus of the thalamus, AMY, lateral geniculate nucleus (LGN) and visual cortex, which belong to the cortical and subcortical pathways for visual fear processing, we investigated the temporal relationship between these regions in visual processing in rats. Read More

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Temporal coherency of mechanical stimuli modulates tactile form perception.

Sci Rep 2021 Jun 3;11(1):11737. Epub 2021 Jun 3.

Research Institute for Electronic Science, Hokkaido University, Sapporo, Japan.

The human hand can detect both form and texture information of a contact surface. The detection of skin displacement (sustained stimulus) and changes in skin displacement (transient stimulus) are thought to be mediated in different tactile channels; however, tactile form perception may use both types of information. Here, we studied whether both the temporal frequency and the temporal coherency information of tactile stimuli encoded in sensory neurons could be used to recognize the form of contact surfaces. Read More

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Physiological diversity influences detection of stimulus envelope and fine structure in neurons of the medial superior olive.

J Neurosci 2021 Jun 1. Epub 2021 Jun 1.

Department of Neuroscience, University of Texas at Austin, Austin, TX 78712

The neurons of the medial superior olive (MSO) of mammals extract azimuthal information from the delays between sounds reaching the two ears (interaural time differences, or ITDs). Traditionally, all models of sound localization have assumed that MSO neurons represent a single population of cells with specialized and homogeneous intrinsic and synaptic properties that enable detection of synaptic coincidence on a time scale of tens to hundreds of microseconds. Here, using patch-clamp recordings from large populations of anatomically labeled neurons in brainstem slices from male and female Mongolian gerbils (s), we show that MSO neurons are far more physiologically diverse than previously appreciated, with properties that depend regionally on cell position along the topographic map of frequency. Read More

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Detection of movement related cortical potentials in freehand drawing on digital tablet.

J Neurosci Methods 2021 May 31;360:109231. Epub 2021 May 31.

Dipartimento di Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili (DINOGMI), Università degli Studi di Genova, Largo Daneo 3, 16132, Genova, Italy. Electronic address:

Background: Cortical activity connected to movements has been investigated long since, and is related, among other factors, to saliency of the gesture. However, experiments performed on movements in actual situations are rare, as most of them have been performed in laboratory simulations. Besides, no research seems to have been carried out on subjects during freehand drawing. Read More

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A new and facile route to prepare gold nanoparticle clusters on anodic aluminium oxide as a SERS substrate.

Talanta 2021 Sep 15;232:122426. Epub 2021 Apr 15.

Department of Nanotechnology and Nanomedicine, Hacettepe University, Beytepe, 06800, Ankara, Turkey; Department of Food Engineering, Faculty of Engineering, Hacettepe University, Beytepe, 06800, Ankara, Turkey. Electronic address:

In the present study, a new SERS-active gold nanoparticle clusters having a flower-shape have been prepared easily on nano porous anodic aluminium oxide (AAO) by immersing it in auric chloride solution without any need for complex production steps. In this process, presented for the first time, the metallic aluminum which were released under the influence of chloride ions due to pitting corrosion act as a reducing agent, while gold ions were reduced onto the AAO layer based on the difference in standard reduction potentials between aluminum and gold. Gold nanoparticle clusters on AAO layer formed "hot spots" providing enhanced Raman signal. Read More

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September 2021

[Cognitive function analysis of chronic lead poisoning in adults].

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2021 May;39(5):343-345

Hubei General Hospital, Wuhan 430060, China.

To explore the changes of the auditory event-related potentials P300 and the Montreal Cognitive Assessment (MoCA) in the chronic mild lead poisoning in order to find out the impairment of cognitive function and intervene early. In February 2020, 50 patients with chronic mild lead poisoning in Wuhan Center for Prevention and Treatment of Occupational Diseases from June 2011 to June 2015 were selected as the case group, and 50 healthy people were selected as the control group. The changes of auditory event-related potential P300 and MOCA of the two groups were analyzed. Read More

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Platinum-Based Interdigitated Micro-Electrode Arrays for Reagent-Free Detection of Copper.

Sensors (Basel) 2021 May 19;21(10). Epub 2021 May 19.

Nanotechnology Group, Tyndall National Institute, T12 R5CP Cork, Ireland.

Water is a precious resource that is under threat from a number of pressures, including, for example, release of toxic compounds, that can have damaging effect on ecology and human health. The current methods of water quality monitoring are based on sample collection and analysis at dedicated laboratories. Recently, electrochemical-based methods have attracted a lot of attention for environmental sensing owing to their versatility, sensitivity and their ease of integration with cost effective, smart and portable readout systems. Read More

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On the Wireless Microwave Sensing of Bacterial Membrane Potential in Microfluidic-Actuated Platforms.

Sensors (Basel) 2021 May 14;21(10). Epub 2021 May 14.

Department of Signal Theory and Communications, Universitat Politècnica de Catalunya-BarcelonaTech, 08034 Barcelona, Spain.

The investigation of the electromagnetic properties of biological particles in microfluidic platforms may enable microwave wireless monitoring and interaction with the functional activity of microorganisms. Of high relevance are the action and membrane potentials as they are some of the most important parameters of living cells. In particular, the complex mechanisms of a cell's action potential are comparable to the dynamics of bacterial membranes, and consequently focusing on the latter provides a simplified framework for advancing the current techniques and knowledge of general bacterial dynamics. Read More

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A Comparison among Different Ways to Investigate Composite Materials with Lock-In Thermography: The Multi-Frequency Approach.

Materials (Basel) 2021 May 12;14(10). Epub 2021 May 12.

Politecnico di Bari, Department of Mechanics, Mathematics & Management, Via Orabona 4, 70125 Bari, Italy.

The main goal of non-destructive testing is the detection of defects early enough to avoid catastrophic failure with particular interest for the inspection of aerospace structures; under this aspect, all methods for fast and reliable inspection deserve special attention. In this sense, active thermography for non-destructive testing enables contactless, fast, remote, and not expensive control of materials and structures. Furthermore, different works have confirmed the potentials of lock-in thermography as a flexible technique for its peculiarity to be performed by means of a low-cost set-up. Read More

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Event-related potentials in insomnia reflect altered perception of sleep.

Sleep 2021 Jun 1. Epub 2021 Jun 1.

Medical Center - University of Freiburg, Department of Psychiatry and Psychotherapy, Section of Clinical Psychology and Psychophysiology, Hauptstraße, Freiburg, Germany.

Study Objectives: Insomnia is defined by the subjective complaint of poor sleep as well as daytime impairments. Since polysomnography (PSG) typically shows only modest sleep impairment, some still unidentified property of sleep, not mirrored in PSG, may be modified in insomnia.One possible mechanistic hypothesis is that insomnia patients may be more sensitive to inevitably occurring internal or external stimuli during the night, causing brief sleep disruptions then perceived as wake time. Read More

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Optical Spike Detection and Connectivity Analysis With a Far-Red Voltage-Sensitive Fluorophore Reveals Changes to Network Connectivity in Development and Disease.

Front Neurosci 2021 13;15:643859. Epub 2021 May 13.

Department of Chemistry, University of California, Berkeley, Berkeley, CA, United States.

The ability to optically record dynamics of neuronal membrane potential promises to revolutionize our understanding of neurobiology. In this study, we show that the far-red voltage sensitive fluorophore, Berkeley Red Sensor of Transmembrane potential-1, or BeRST 1, can be used to monitor neuronal membrane potential changes across dozens of neurons at a sampling rate of 500 Hz. Notably, voltage imaging with BeRST 1 can be implemented with affordable, commercially available illumination sources, optics, and detectors. Read More

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