25,507 results match your criteria posttraumatic stress


Hard Boiled: Alcohol Use as a Risk Factor for MDMA-Induced Hyperthermia: a Systematic Review.

Neurotox Res 2021 Sep 23. Epub 2021 Sep 23.

Department of Psychiatry, Amsterdam University Medical Center, University of Amsterdam, P.O. Box 22660, 1100 DD, Amsterdam, The Netherlands.

Although MDMA (ecstasy) is a relatively safe recreational drug and is currently considered for therapeutic use for the treatment of posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD), recreational MDMA use occasionally elicits hyperthermia and hyponatremia, sometimes with a fatal outcome. Specific risk factors for both adverse effects are profuse sweating while vigorously dancing under unfavorable conditions such as high ambient temperatures and insufficient fluid suppletion which result in dehydration. Concomitant use of MDMA and alcohol is highly prevalent, but adds to the existing risk, because alcohol facilitates the emergence of MDMA-induced adverse events, like hyperthermia, dehydration, and hyponatremia. Read More

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September 2021

Types of trauma-related blame following interpersonal trauma.

Psychol Trauma 2021 Sep 23. Epub 2021 Sep 23.

Department of Psychology, University of Minnesota Duluth.

Objective: The Diagnostic and Statistical Manual of Mental Disorders (DSM) now includes trauma-related blame as a symptom of posttraumatic stress disorder (PTSD Criterion D3; American Psychiatric Association, 2013). To date, most blame research has utilized quantitative scales, primarily for self-blame, with little attention to other forms of blame. The aims of this study were to (a) identify the common blame types reported by interpersonal trauma survivors through open-ended statements, and (b) explore how well these blame types converge with the Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5) screener's blame item and total scores. Read More

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September 2021

Unity or diversity of executive functioning in children and adolescents with post-traumatic stress symptoms? A systematic review and meta-analysis.

Child Neuropsychol 2021 Sep 23:1-20. Epub 2021 Sep 23.

PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.

For some children, psychological reactions to a traumatic event develop into severe or persistent post-traumatic stress symptoms (PTSS) or the clinical condition of post-traumatic stress disorder (PTSD). Cognitive problems in children with PTSS have been reported, but it is not clear which specific functions are affected. Executive functions is a domain of particular interest, given its importance for academic performance and social and emotional functioning. Read More

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September 2021

Physical functioning and mental health treatment initiation and retention for veterans with posttraumatic stress disorder: a prospective cohort study.

BMC Health Serv Res 2021 Sep 23;21(1):1005. Epub 2021 Sep 23.

Center for Care Delivery & Outcomes Research, Minneapolis VA Health Care System, One Veterans Dr, MN, 55417, Minneapolis, United States.

Background: Most US adults with posttraumatic stress disorder (PTSD) do not initiate mental health treatment within a year of diagnosis. Increasing treatment uptake can improve health and quality of life for those with PTSD. Individuals with PTSD are more likely to report poor physical functioning, which may contribute to difficulty with treatment initiation and retention. Read More

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September 2021

Assessing the Risk Factors for Anxiety, Depression, and Posttraumatic Stress Disorder through the International Pemphigus and Pemphigoid Foundation.

J Eur Acad Dermatol Venereol 2021 Sep 22. Epub 2021 Sep 22.

University of Illinois at Chicago, Department of Dermatology, Chicago, Illinois, USA.

Autoimmune blistering diseases (AIBD) are associated with significant impact on quality of life with numerous associated psychiatric comorbidities. We sought to investigate disease-related risk factors for the development of depression, anxiety, and posttraumatic stress disorder (PTSD) in AIBD patients. A cross-sectional cohort study was conducted at the University of Illinois at Chicago with Institutional Review Board exemption. Read More

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September 2021

The Impact of Volunteering at a Family Camp for Children and Adolescents With Cancer: The Experience of Pediatric Intensive Care Nurses.

J Nurs Adm 2021 Oct;51(10):526-531

Author Affiliations: CEO (Ms Butterworth), AIM Youth Mental Health, Carmel, California and Founder, Jacob's Heart Children's Cancer Support Services, Watsonville, California; and Director of Nursing Research (Dr Nasr), Stanford Children's Health, Stanford School of Medicine; and Nurse Scientist and Postdoctoral Fellow in Palliative Care (Dr Pyke-Grimm), Stanford Children's Health; and PICU Nurse (Ms Swisher), Stanford Children's Health, Palo Alto, California; and SVP Patient Care Services and Chief Nursing Executive (Dr Johnson), Queens Health System, Honolulu, Hawaii.

Objective: This study explored the experience of pediatric ICU (PICU) nurses who volunteered at a camp for families of children and adolescents with cancer.

Background: PICU nurses are at risk of developing symptoms of posttraumatic stress disorder, compassion fatigue, depression, and burnout due to exposure(s) to traumatic events. Spending time with patients, families, and nurse colleagues at camp may reduce the effects of this exposure. Read More

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October 2021

Health Trends among 9/11 Responders from 2011-2021: A Review of World Trade Center Health Program Statistics.

Prehosp Disaster Med 2021 Oct 2;36(5):621-626. Epub 2021 Sep 2.

Edith Cowan University, School of Medical and Health Sciences, Joondalup, Perth, Western Australia.

Introduction: In a single day, the September 11, 2001 US terrorist attacks (9/11) killed nearly 3,000 people, including 412 first responders. More than 91,000 responders were exposed to a range of hazards during the recovery and clean-up operation that followed. Various health programs track the on-going health effects of 9/11, including the World Trade Center (WTC) Health Program (WTCHP). Read More

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October 2021

Virtual Reality to Improve Sequelae of the Postintensive Care Syndrome: A Multicenter, Randomized Controlled Feasibility Study.

Crit Care Explor 2021 Sep 14;3(9):e0538. Epub 2021 Sep 14.

Department of Intensive Care, Erasmus Medical Centre, Rotterdam, The Netherlands.

Psychologic sequelae after critical illness, part of the postintensive care syndrome, significantly decrease quality of life. A robustly effective treatment intervention is currently lacking. Virtual reality has beneficial effects on several non-ICU-related psychologic disorders. Read More

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September 2021

PTSD Symptoms and Sleep Quality of COVID-19 Patients During Hospitalization: An Observational Study from Two Centers.

Nat Sci Sleep 2021 14;13:1519-1531. Epub 2021 Sep 14.

Lab for Post-Traumatic Stress Disorder, Faculty of Psychology and Mental Health, Naval Medical University, Shanghai, 200433, People's Republic of China.

Background: The outbreak of COVID-19 has developed into a pandemic. Data are required that specifically address the psychological consequences in COVID-19 confirmed patients. This study mainly aimed to examine posttraumatic stress disorder (PTSD) symptoms and sleep quality among COVID-19 confirmed patients during hospitalization. Read More

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September 2021

The Influence of a Peer Support Camp on Mitigating Emotional Distress in Siblings of Children With Cancer.

J Pediatr Oncol Nurs 2021 Sep 21:10434542211041929. Epub 2021 Sep 21.

Department of Pediatrics Hematology/Oncology, 6429Stanford University Stanford, CA, USA.

Siblings of children with cancer often experience anxiety and posttraumatic stress symptoms (PTSS), which negatively impact their self-esteem due to emotionally upsetting circumstances. The purpose of this longitudinal quantitative study was to investigate changes in anxiety, PTSS, and self-esteem of youth who participated in a peer support camp for siblings of children with cancer. A longitudinal study examined changes over time. Read More

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September 2021

Prefrontal cortex, amygdala, and threat processing: implications for PTSD.

Neuropsychopharmacology 2021 Sep 20. Epub 2021 Sep 20.

Department of Psychology, Harvard University, Cambridge, MA, USA.

Posttraumatic stress disorder can be viewed as a disorder of fear dysregulation. An abundance of research suggests that the prefrontal cortex is central to fear processing-that is, how fears are acquired and strategies to regulate or diminish fear responses. The current review covers foundational research on threat or fear acquisition and extinction in nonhuman animals, healthy humans, and patients with posttraumatic stress disorder, through the lens of the involvement of the prefrontal cortex in these processes. Read More

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September 2021

Lamotrigine for Treating Anger in Veterans With Posttraumatic Stress Disorder.

Clin Neuropharmacol 2021 Sep-Oct 01;44(5):184-185

Phoenix VA Health Care System, Phoenix, AZ.

Abstract: Lamotrigine is an antiepileptic drug that was Food and Drug Administration approved in 2003 for use in the maintenance treatment of bipolar I disorder to delay the time to recurrence of new mood episodes. The mechanism by which lamotrigine achieves its therapeutic effect in the treatment of bipolar disorder is unknown. Here, we report on 2 Veterans with combat-related posttraumatic stress disorder (PTSD) endorsing significant anger, aggression, and agitation, who were treated with selective serotonin reuptake inhibitors, but whose residual symptoms of anger and aggression were ultimately successfully managed with lamotrigine augmentation. Read More

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September 2021

The Effect of Reminiscence Therapy Using Virtual Reality on Apathy in Residential Aged Care: Multisite Nonrandomized Controlled Trial.

J Med Internet Res 2021 Sep 20;23(9):e29210. Epub 2021 Sep 20.

UniSA Justice & Society, University of South Australia, Adelaide, South Australia, Australia.

Background: Apathy is a frequent and underrecognized neurological disorder symptom. Reduced goal-directed behavior caused by apathy is associated with poor outcomes for older adults in residential aged care. Recommended nonpharmacological treatments include person-centered therapy using information and communication technology. Read More

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September 2021

Reactions to Laboratory-Based Trauma Research in a Sample of Incarcerated Women.

J Empir Res Hum Res Ethics 2021 Sep 20:15562646211043632. Epub 2021 Sep 20.

6640Idaho State University, Pocatello, USA.

An evidence-based approach to research ethics is critical to ethical research but little is known about how trauma survivors-especially those from vulnerable populations-respond to laboratory-based trauma research. One hundred four incarcerated women ( = 64 rape survivors) reported their traumatic life experiences, listened to and responded to an audio recording of a dating interaction that culminates in a completed rape, and then reported their responses to their participation. Compared to the control group ( = 40), rape survivors ( = 64) had more posttraumatic stress disorder symptoms and these symptoms were associated with more emotional responding. Read More

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September 2021

Effects of Mindfulness-Based Internet Intervention on ICD-11 Posttraumatic Stress Disorder and Complex Posttraumatic Stress Disorder Symptoms: a Pilot Randomized Controlled Trial.

Mindfulness (N Y) 2021 Sep 11:1-13. Epub 2021 Sep 11.

Center for Psychotraumatology, Institute of Psychology, Vilnius University, Vilnius, Lithuania.

Objectives: A substantial proportion of trauma survivors with posttraumatic stress disorder (PTSD) and complex PTSD (CPTSD) continue to experience symptoms even after trauma-focused therapies. Internet-based interventions could facilitate access to treatment for PTSD and CPTSD. The current pilot study aimed to investigate the effects of mindfulness-based internet intervention on PTSD and CPTSD symptoms. Read More

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September 2021

Factors associated with post-traumatic growth in response to the COVID-19 pandemic: Results from a national sample of U.S. military veterans.

Soc Sci Med 2021 Sep 15;289:114409. Epub 2021 Sep 15.

Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA; U.S. Department of Veterans Affairs National Center for PTSD, VA Connecticut Healthcare System, West Haven, CT, USA; Department of Social and Behavioral Sciences, Yale School of Public Health, New Haven, CT, USA.

Rationale: The COVID-19 pandemic has had numerous negative effects globally, contributing to mortality, social restriction, and psychological distress. To date, however, the majority of research on the psychological impact of the COVID-19 pandemic has focused on negative psychological outcomes, such as depression, anxiety, and posttraumatic stress disorder (PTSD).

Objective: Although there is debate about the constructive vs. Read More

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September 2021

After a disaster: Validation of PTSD checklist for DSM-5 and the four- and eight-item abbreviated versions in mental health service users.

Psychiatry Res 2021 Aug 29;305:114197. Epub 2021 Aug 29.

Department of Psychiatry and Mental Health, Medicine Faculty, National Autonomous University of Mexico, Avenida Universidad 3000, Colonia Universidad Nacional Autónoma de México, Ciudad Universitaria, Alcaldía de Coyoacán, Mexico City, 04510, Mexico.

Posttraumatic stress disorder (PTSD) is a common and disabling condition developing in one of four survivors after an earthquake. Brief and self-reported validated measures for assessing PTSD symptom severity are necessary to improve care access and assess disorder progress and treatment response. Therefore, we evaluated the psychometric properties of the PTSD-Checklist for the DSM-5 (PCL-5) of 20-, 8- and 4-item in patients that sought specialized mental health services after a catastrophic earthquake that stroke Mexico on September 19th, 2017. Read More

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A network analysis of two conceptual approaches to the etiology of PTSD.

J Anxiety Disord 2021 Sep 10;84:102479. Epub 2021 Sep 10.

Department of Psychological Sciences, Auburn University, Auburn, AL, USA.

Two prominent conceptual models of posttraumatic stress disorder (PTSD) are the cognitive model, associated with cognitive processing therapy (CPT; Resick & Schnicke, 1992), and the functional contextualist model, underlying acceptance and commitment therapy (ACT; Hayes et al., 1999). Network analysis was used to examine dynamic interactions among cognitive (relating to CPT) and functional contextualistic (relating to ACT) variables and PTSD symptoms in a sample of 722 trauma-exposed adults. Read More

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September 2021

A SMART approach to optimizing delivery of an mHealth intervention among cancer survivors with posttraumatic stress symptoms.

Contemp Clin Trials 2021 Sep 16;110:106569. Epub 2021 Sep 16.

Department of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America; Department of Psychology in Psychiatry, Weill Cornell Medicine, New York, NY, United States of America.

Background/aims: Many cancer survivors who received intensive treatment such as hematopoietic stem cell transplantation (HCT) experience posttraumatic stress disorder (PTSD) symptoms. PTSD is associated with lower quality of life and other symptoms that require clinical treatment. The iterative treatment decisions that happen in clinical practice are not adequately represented in traditional randomized controlled trials (RCT) of PTSD treatments. Read More

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September 2021

Distress in a Pandemic - The Association of the Coronavirus Disease-2019 (COVID-19) Pandemic with Distress and Quality of Life in Hematopoietic Stem Cell Transplantation (HSCT).

Transplant Cell Ther 2021 Sep 15. Epub 2021 Sep 15.

Harvard Medical School, Boston MA; Massachusetts General Hospital, Boston MA.

Background: The global coronavirus disease 2019 (COVID-19) pandemic has drastically disrupted cancer care, potentially exacerbating patients' distress levels. Patients undergoing HSCT may be especially vulnerable to this pandemic stress. However, the associations of the COVID-19 pandemic with distress, fatigue, and QOL are not well understood in this population. Read More

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September 2021

Neural Responsivity to Reward versus Punishment Shortly after Trauma Predicts Long-term Development of Post-Traumatic Stress Symptoms.

Biol Psychiatry Cogn Neurosci Neuroimaging 2021 Sep 14. Epub 2021 Sep 14.

Sagol Brain Institute Tel-Aviv, Wohl Institute for Advanced Imaging, Tel Aviv Sourasky Medical Center, Tel-Aviv, Israel; Sagol School of Neuroscience, Tel-Aviv University, Tel-Aviv, Israel; School of Psychological Sciences, Faculty of Social Sciences, Tel-Aviv University, Tel-Aviv, Israel; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel. Electronic address:

Background: Processing negative and positive valenced stimuli involve multiple brain regions including the amygdala and ventral striatum (VS). Post-Traumatic Stress Disorder (PTSD) is often associated with hyper-responsivity to negatively valenced, yet recent evidence also points to deficient positive valence functioning. It is yet unclear what is the relative contribution of such opposing valence processing shortly after trauma to the development of chronic PTSD. Read More

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September 2021

A community-based trial of a psychosocial eHealth intervention for parents of children with cancer.

Pediatr Blood Cancer 2021 Sep 17:e29352. Epub 2021 Sep 17.

Nemours Center for Healthcare Delivery Science, Wilmington, Delaware, USA.

Background: The Electronic Surviving Cancer Competently Intervention Program (eSCCIP), a psychosocial eHealth intervention for parents and caregivers of children with cancer (parents), was delivered in a community-based psychosocial oncology center. Primary endpoints were intervention acceptability, feasibility, and accessibility, with a secondary exploratory focus on psychosocial outcomes.

Procedure: Oncology therapists in a psychosocial oncology center were trained in eSCCIP delivery. Read More

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September 2021

The Association Between Service Connection and Treatment Outcome in Veterans Undergoing Residential PTSD Treatment.

Psychiatr Q 2021 Sep 17. Epub 2021 Sep 17.

VA Center for Clinical Management Research, VA Ann Arbor Healthcare System/Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA.

The Department of Veterans Affairs has invested significant time and resources into the treatment of posttraumatic stress disorder (PTSD). Despite concerted efforts, a significant portion of patients do not respond optimally to trauma-focused treatment. One of the factors that has been hypothesized to be associated with treatment response is participation in the Veterans Benefits Administration service-connected disability process. Read More

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September 2021

Sex differences in PTSD risk: evidence from post-conflict populations challenges the general assumption of increased vulnerability in females.

Eur J Psychotraumatol 2021 9;12(1):1930702. Epub 2021 Sep 9.

vivo International e.V, Konstanz, Germany.

: Next to the dose-dependent effect of trauma load, female sex represents a well-established risk factor for PTSD. Exposure to particularly toxic traumatic event types, different coping styles, and biological risk factors are frequently listed as potential causes for the increased PTSD vulnerability in females. Nevertheless, sex differences have not been consistently observed in all study populations. Read More

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September 2021

Mental and physical health, and long-term quality of life among service members injured on deployment.

Health Qual Life Outcomes 2021 Sep 16;19(1):220. Epub 2021 Sep 16.

Operational Readiness Directorate, Naval Health Research Center, 140 Sylvester Road, San Diego, CA, 92106, USA.

Background: More than 52,000 casualties have been documented in post-9/11 conflicts. Service members with extremity injuries (EIs) or traumatic brain injury (TBI) may be at particular risk for long-term deficits in mental and physical health functioning compared with service members with other injuries.

Methods: The present study combined medical records with patient reports of mental health and health-related quality of life (HRQOL) for 2,537 service members injured in overseas contingency operations who participated in the Wounded Warrior Recovery Project. Read More

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September 2021

Does attachment predict the outcome of cognitive processing therapy for posttraumatic stress disorder in adolescent patients with interpersonal traumatization?

Psychother Res 2021 Sep 17:1-13. Epub 2021 Sep 17.

Department of Psychology, Catholic University Eichstätt-Ingolstadt, Eichstätt, Germany.

The attachment has emerged as a significant predictor of psychotherapy outcome. However, studies on trauma-focused treatments and adolescent samples are sparse. We analyzed the data of 43 adolescents and young adults (aged 14-21 years) with clinically relevant abuse-related posttraumatic stress disorder (PTSD) who were undergoing developmentally adapted cognitive processing therapy (D-CPT) within a multicenter, randomized clinical trial (German Clinical Trials Register; identifier: DRKS00004787). Read More

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September 2021

VOICES: An efficacious trauma-informed, gender-responsive cannabis use intervention for justice and school-referred girls with lifetime substance use history.

Drug Alcohol Depend 2021 Jul 28;228:108934. Epub 2021 Jul 28.

The Warren Alpert Medical School of Brown University, Department of Psychiatry and Human Behavior, 222 Richmond St, Providence, RI, 02903, United States. Electronic address:

Background: Girls have unique developmental pathways to substance use and justice system involvement, warranting gender-responsive intervention. We tested the efficacy of VOICES (a 12-session, weekly trauma-informed, gender-responsive substance use intervention) in reducing substance use and HIV/STI risk behaviors among justice- and school-referred girls.

Methods: Participants were 113 girls (M = 15. Read More

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Reversed patterns of resting state functional connectivity for females vs. males in posttraumatic stress disorder.

Neurobiol Stress 2021 Nov 1;15:100389. Epub 2021 Sep 1.

Department of Psychiatry and the New York State Psychiatric Institute, Columbia University Medical Center, 1071 Riverside Dr., New York, NY, USA.

Background: Posttraumatic stress disorder (PTSD) is twice as prevalent among females as compared to males following potentially traumatic events. While there is evidence for aberrant functional connectivity between hubs of the central executive network (CEN), salience network (SN), and the default mode network (DMN) in PTSD, little is known regarding sex-specificity of this connectivity. The current study aims to directly examine sex-specific resting-state functional connectivity (rs-FC) in trauma exposed males and females, with and without PTSD. Read More

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November 2021