15,082 results match your criteria postsurgical


Current Advancements in Animal Models of Postsurgical Lymphedema: A Systematic Review.

Adv Wound Care (New Rochelle) 2021 Jun 15. Epub 2021 Jun 15.

University of Southern California Keck School of Medicine, 12223, Division of Plastic and Reconstructive Surgery, Los Angeles, California, United States.

Significance: Secondary lymphedema is a debilitating disease caused by lymphatic dysfunction characterized by chronic swelling, dysregulated inflammation, disfigurement, and compromised wound healing. Since there is no effective cure, animal model systems that support basic science research into the mechanisms of secondary lymphedema are critical to advancing the field. Recent Advances: Over the last decade, lymphatic research has led to the improvement of existing animal lymphedema models and the establishment of new models. Read More

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Impact of median lobe on urinary function after robotic prostatectomy.

Prostate 2021 Jun 14. Epub 2021 Jun 14.

Robotic Surgery, OhioHealth Dublin Methodist Hospital, Dublin, Ohio, USA.

Background: Enlarged median lobes (ML) can be technically challenging, particularly during bladder-neck dissection, and may affect urinary functional outcomes of robotic radical prostatectomy (RARP). If known, the impact of potentially larger bladder necks on continence and chronic obstruction on postoperative urinary symptoms might aid patient counseling. We assessed the impact of intraoperatively identified median lobes (ML) on urinary function. Read More

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Outcomes Following Discectomy for Far Lateral Disc Herniation Are Not Predicted by Obstructive Sleep Apnea.

Cureus 2021 May 9;13(5):e14921. Epub 2021 May 9.

Department of Neurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.

Introduction Previous studies have demonstrated that obstructive sleep apnea (OSA) is associated with adverse postoperative outcomes, but few studies have examined OSA in a purely spine surgery population. This study investigates the association of the STOP-Bang questionnaire, a screening tool for undiagnosed OSA, with adverse events following discectomy for far lateral disc herniation (FLDH). Methods All adult patients (n = 144) who underwent FLDH surgery at a single, multihospital, academic medical center (2013-2020) were retrospectively enrolled. Read More

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Transit Time Measurement in Indicator Dilution Curves: Overcoming the Missing Ground Truth and Quantifying the Error.

Front Physiol 2021 28;12:588120. Epub 2021 May 28.

Institute of Biomedical Engineering, Karlsruhe Institute of Technology, Karlsruhe, Germany.

The vascular function of a vessel can be qualitatively and intraoperatively checked by recording the blood dynamics inside the vessel via fluorescence angiography (FA). Although FA is the state of the art in proving the existence of blood flow during interventions such as bypass surgery, it still lacks a quantitative blood flow measurement that could decrease the recurrence rate and postsurgical mortality. Previous approaches show that the measured flow has a significant deviation compared to the gold standard reference (ultrasonic flow meter). Read More

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Perioperative factors associated with persistent post-surgical pain after hysterectomy, cesarean section, prostatectomy, and donor nephrectomy: a systematic review and meta-analysis.

Pain 2021 Jun 4. Epub 2021 Jun 4.

Department of Anesthesiology, Washington University School of Medicine, St Louis, MO, USA Department of Clinical Medicine, Aarhus University, Aarhus, Denmark The University of Sydney School of Medicine, Sydney, Australia School of Medicine, St Louis University, St Louis, MO, USA Becker Medical Library, Washington University School of Medicine, St Louis, MO, USA.

Abstract: Persistent postsurgical pain (PPSP) is a common, and often disabling postoperative morbidity, but many questions remain about factors associated with PPSP. This systematic review and meta-analysis aimed to identify preoperative, intraoperative and postoperative factors associated with PPSP after gynecological surgeries, namely hysterectomy and cesarean section (C-section), and urological surgeries, namely prostatectomy and donor nephrectomy. Overall, 18 gynecological surgery studies, 4 prostatectomy studies, and 2 donor nephrectomy studies met the review criteria providing data that could be meta-analyzed. Read More

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The lung microbiome in lung transplantation.

J Heart Lung Transplant 2021 May 7. Epub 2021 May 7.

Division of Pulmonary, Allergy and Critical Care Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania; Department of Microbiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

Culture-independent study of the lower respiratory tract after lung transplantation has enabled an understanding of the microbiome - that is, the collection of bacteria, fungi, and viruses, and their respective gene complement - in this niche. The lung has unique features as a microbial environment, with balanced entry from the upper respiratory tract, clearance, and local replication. There are many pressures impacting the microbiome after transplantation, including donor allograft factors, recipient host factors such as underlying disease and ongoing exposure to the microbe-rich upper respiratory tract, and transplantation-related immunosuppression, antimicrobials, and postsurgical changes. Read More

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Case report: An epidural cavernous hemangioma mimicking a dumbbell-shaped neuroma.

Int J Surg Case Rep 2021 Jun 9;84:106069. Epub 2021 Jun 9.

Army Hospital of Rome "Celio", Clinical Pathology Department, Via S. Stefano Rotondo n. 4, 00184 Roma, Italy.

Introduction And Importance: Spinal epidural cavernous hemangiomas are a rare occurrence. This particular case is made even more distinctive by the fact that the lesion mimicked a dumbbell-shaped neuroma. Moreover, it had a very unique localization (wholly epidural, at cervical-thoracic -C7-D1- level). Read More

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Multifunctional magnesium incorporated scaffolds by 3D-Printing for comprehensive postsurgical management of osteosarcoma.

Biomaterials 2021 Jun 4;275:120950. Epub 2021 Jun 4.

Centre for Translational Medicine Research & Development, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China; Key Laboratory of Health Informatics, Chinese Academy of Sciences, Shenzhen, China; CAS-HK Joint Lab of Biomaterials, Shenzhen, China. Electronic address:

Clinical treatment of Osteosarcoma (OS) encounters great challenges of postsurgical tumor recurrence and extensive bone defect. To address these issues, innovative multifunctional PLGA/Mg porous scaffolds were designed for comprehensive postsurgical management of OS. The PLGA/Mg composite scaffolds exhibited several unique features: (1) The multiple functions of Mg particles were explored for the first time to fulfill the requirement for postsurgical management of OS. Read More

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Open Reduction on very late-presenting unreduced posterior elbow dislocation: Still promising treatment option.

Int J Surg Case Rep 2021 Jun 2;84:106056. Epub 2021 Jun 2.

Department of Orthopaedics and Traumatology - Faculty of Medicine - University Padjadjaran - Indonesia.

Background: Neglected dislocation of the elbow is associated with instability, pain, and limitation of elbow function. In developing countries, neglected dislocations of the elbow are quite common, and most patients initially go to local bonesetters, which only aggravates the problem.

Presentation Of Case: Two patients with a history of unreduced posterior elbow dislocation for more than 1 year and were treated by a traditional bonesetter were included in this case study. Read More

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Radiological evaluation of the postsurgical middle ear.

Radiologia 2021 Jun 8. Epub 2021 Jun 8.

Área clínica de Imagen Médica, Hospital Universitario y Politécnico La Fe, Valencia, España.

Objective: The radiological evaluation of the postsurgical middle ear is complex due to the intricate anatomy of this region and the wide variety of procedures and materials used iin middle ear surgery. Knowledge of these factors will enable normal postsurgical changes to be differentiated from complications. This article describes the most common surgical procedures in the middle ear, their indications, and the normal radiological appearance after these procedures. Read More

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Risk factors associated with postoperative respiratory failure in tuberculous empyema patients.

Medicine (Baltimore) 2021 Jun;100(23):e25754

Department of Thoracic Surgery.

Abstract: Our objective was to identify independent risk factors for predicting which patients in the Chinese population would likely develop respiratory failure.A descriptive analysis was conducted of demographic and clinical data of patients with tuberculous empyema (TE) admitted to the Beijing Chest Hospital, Capital Medical University between January 2001 and January 2020. Risk factors associated with postsurgical respiratory failure in TE patients were identified based on results of analyses based on univariable and multivariable logistic regression models. Read More

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Impact of Opioid Prescribing Guidelines on Postoperative Opioid Prescriptions Following Elective Spine Surgery: Results From an Institutional Quality Improvement Initiative.

Neurosurgery 2021 Jun 10. Epub 2021 Jun 10.

Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota, USA.

Background: With a dramatic rise in prescription opioid use, it is imperative to review postsurgical prescribing patterns given their contributions to the opioid epidemic.

Objective: To evaluate the impact of departmental postoperative prescribing guidelines on opioid prescriptions following elective spine surgery.

Methods: Patients undergoing elective cervical or lumbar spine surgery between 2017 and 2018 were identified. Read More

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Monitoring HOTTIP levels on extracellular vesicles for predicting recurrence in surgical non-small cell lung cancer patients.

Transl Oncol 2021 Jun 7;14(8):101144. Epub 2021 Jun 7.

Molecular Oncology and Embryology Laboratory, Human Anatomy Unit, Faculty of Medicine and Health Sciences, University of Barcelona, IDIBAPS, Casanova 143, 08036 Barcelona, Spain; Thoracic Oncology Unit, Hospital Clinic, Barcelona. Electronic address:

In resected non-small cell lung cancer (NSCLC), postsurgical recurrence is the major factor affecting long-term survival. The identification of biomarkers in extracellular vesicles (EV) obtained from serial blood samples after surgery could enhance early detection of relapse and improve NSCLC outcome. Since EV cargo contains long non-coding RNAs (lncRNAs), we aimed to analyze whether the oncogenic lncRNA HOTTIP, which higher expression in tumor tissue was related to worse outcome in NSCLC, could be detected in EV from NSCLC patients and serve as recurrence biomarker. Read More

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Evidence-Based Recommendations for Opioid Prescribing after Endourological and Minimally Invasive Urological Surgery.

J Endourol 2021 Jun 9. Epub 2021 Jun 9.

Johns Hopkins University School of Medicine, Baltimore, Maryland, United States;

Introduction: Procedure-specific guidelines for postsurgical opioid use can decrease overprescribing and facilitate opioid stewardship. Initial recommendations were based on feasibility data from limited pilot studies. This study aims to refine opioid prescribing recommendations for endourological and minimally invasive urological procedures by integrating emerging clinical evidence with a panel consensus. Read More

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Impact of intermediate to high-doses of methylprednisolone on mortality rate in patients with COVID-19 pneumonia-induced severe systemic inflammation.

Int J Clin Pract 2021 Jun 9:e14479. Epub 2021 Jun 9.

Medical Director, Doctor Peset University Hospital, Valencia, Spain.

Introduction: In addition to respiratory support needs, patients´ characteristics to guide indication or timing of corticosteroid treatment in COVID-19 patients are not completely established. This study aimed to evaluate the impact of methylprednisolone on mortality rate in patients with COVID-19 pneumonia-induced severe systemic inflammation (PI-SSI).

Methods: Between March 9 and May 5, 2020 (final follow-up July 2, 2020), a retrospective cohort study was conducted in hospitalized patients with COVID-19 PI-SSI (≥2 inflammatory biomarkers (IB): temperature ≥38ºC, lymphocyte ≤800cell/microL, C-reactive protein ≥100mg/L, lactate dehydrogenase ≥300units/L, ferritin ≥1000mcg/L, D-dimer ≥500ng/mL). Read More

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Intranodal Lymphangiography With High-Dose Ethiodized Oil Shows Efficient Results in Patients With Refractory, High-Output Postsurgical Chylothorax: A Retrospective Study.

AJR Am J Roentgenol 2021 Jun 9:1-6. Epub 2021 Jun 9.

Department of Radiology, University Hospitals Leuven, Herestraat 49, B-3000 Leuven, Belgium.

The purpose of this study is to evaluate the safety and efficacy of intranodal lymphangiography (INL) with high-dose ethiodized oil in patients with postoperative refractory chylothorax. A retrospective review of a cohort of 18 patients with refractory postoperative chylothorax seen between May 2015 and March 2019 was conducted. All patients underwent intranodal lymphangiography with high doses of ethiodized oil (mean, 75 mL; range, 40-140 mL). Read More

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Do Simulated Hospital Admissions Reflect Reality? A Qualitative Study of Volunteer Well-Being During a 24-Hr Simulated Hospitalization.

HERD 2021 Jun 9:19375867211020682. Epub 2021 Jun 9.

Department of Surgery, Radboud University Medical Center, Nijmegen, the Netherlands.

Objectives: This study aims to delineate if and how healthy volunteers admitted to simulated care can aid in understanding real well-being experiences of in-hospital surgical patients.

Background: Scientific research is necessary to understand the mediating effect of healthcare design on patient outcomes. Studies with patients are, however, difficult to conduct as they require substantial funding, time, and research capacity, and recovering patients are often not willing or able to participate. Read More

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A systematic approach to epicardial echocardiography in pediatric cardiac surgery: An important but underutilized intraoperative tool.

Ann Pediatr Cardiol 2021 Apr-Jun;14(2):192-200. Epub 2021 May 3.

Department of Pediatric and Congenital Heart Sciences, Fortis Escorts Heart Institute, New Delhi, India.

Intraoperative echocardiography is an integral component of the peri-operative management of pediatric heart disease. It confirms the adequacy of surgery, identifies residual lesions, and can provide useful hemodynamic data. It, therefore, helps to decide on the need for revision of repair and guides the postoperative management strategy. Read More

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Epidural blood patch to treat a postsurgical cerebrospinal fluid leak using central line kit.

Pain Manag 2021 Jun 9. Epub 2021 Jun 9.

Department of Anesthesiology Critical Care Medicine, Division of Pain Medicine, Children's Hospital Los Angeles, Los Angeles, CA 90027, USA.

Epidural blood patches are considered definitive treatment for postdural puncture headache in adult patients. However, they are infrequently used in children or in patients with altered spine anatomy. In patients who have undergone recent spine surgery, the lumbar epidural space can be approached safely via the caudal canal. Read More

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Volumetry and Surgical Grading Systems for Vestibular Schwannoma Size Assessment and their Relationship to Postoperative Facial Nerve Function.

J Neurol Surg A Cent Eur Neurosurg 2021 Jun 7. Epub 2021 Jun 7.

Department of Neuroradiology, University Hospital Erlangen, Erlangen, Germany.

Background And Study Aims:  Treatment modalities in vestibular schwannoma (VS) are difficult to compare since different techniques for size measurements are used. The purpose of this study was to evaluate the relation between different tumor size grading systems regarding their compatibility as well as the relationship to facial nerve outcome facilitating comparisons of different studies.

Material And Methods:  In this retrospective study, preoperative magnetic resonance imaging of 100 patients with surgically treated VS was evaluated regarding total tumor volume and anatomical extension based on the Koos and Samii classification, as well as volumetric and maximal diameter measures. Read More

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The hidden secrets of a neutral pH-blood gas analysis of postoperative patients according to the Stewart approach.

Perioper Med (Lond) 2021 Jun 8;10(1):15. Epub 2021 Jun 8.

Department of Anesthesiology, Erasmus University Medical Center, Dr. Molewaterplein 40, 3015, GD, Rotterdam, The Netherlands.

Background: The superiority of either the traditional or Stewart based approach to acid-base balance has focused primarily on analyzing metabolic acidemia, with little attention given to patients with neutral pH. In this study, we evaluate metabolic disturbances in patients in the immediate postoperative period focusing on patients with neutral pH, while comparing the Stewart and traditional approach.

Methods: We conducted a single center retrospective observational cohort study. Read More

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Long-term Outcomes After Anal Fistula Surgery: Results From Two University Hospitals in Thailand.

Ann Coloproctol 2021 Jun 7. Epub 2021 Jun 7.

Department of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Purpose: This study aimed to evaluate long-term outcomes after anal fistula surgery from university hospitals in Thailand.

Methods: A prospectively collected database of patients with cryptoglandular anal fistula undergoing surgery from 2011 to 2017 in 2 university hospitals was reviewed. Outcomes were treatment failure (persistent or recurrent fistula), fecal continence status, and chronic postsurgical pain. Read More

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Short-Term, Retrospective Radiographic Evaluation Comparing Pre- and Postoperative Measurements in the Chevron and Minimally Invasive Distal Metatarsal Osteotomy for Hallux Valgus Correction.

J Foot Ankle Surg 2021 May 1. Epub 2021 May 1.

Attending Physician, Physicians Footcare, Florence, SC.

Various techniques exist for correction of mild to moderate hallux valgus (HAV) deformity. Recently, minimally invasive distal metatarsal osteotomy (MIDMO) has gained popularity for HAV correction. This retrospective radiographic review aims to report the surgical correction obtained by the chevron and MIDMO osteotomies at a single institution between 2012 and 2017. Read More

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Editorial Commentary: Tranexamic Acid Is Beneficial in the Very Early Postoperative Period in Anterior Cruciate Ligament Reconstruction Patients.

Arthroscopy 2021 Jun;37(6):1890-1891

National Yang-Ming University.

Tranexamic acid (TXA) has been administrated in many orthopaedic surgical procedures to decrease perioperative and postsurgical bleeding. Relatively scant literature exists regarding the effect of TXA in patients after anterior cruciate ligament reconstruction. Currently, most evidence shows that within about 1 month after anterior cruciate ligament reconstruction, TXA can effectively reduce postoperative joint swelling and pain, as well as the aspiration rate. Read More

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Breast reconstruction after breast cancer surgery - persistent pain and quality of life 1-8 years after breast reconstruction.

Scand J Pain 2021 Jun 4. Epub 2021 Jun 4.

Department of Anaesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Objectives: To assess the long-term outcome of breast reconstructions with special focus on chronic postsurgical pain (CPSP) in a larger cohort of breast cancer survivors.

Methods: A cross-sectional study on 121 women with mastectomy and breast reconstruction after mean 2 years 4 months follow up. The mean time from breast reconstruction to the follow-up visit was 4 years 2 months. Read More

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Medial cortical positive support: A key factor for the postoperative stability of proximal humerus fractures.

Medicine (Baltimore) 2021 Jun;100(22):e26073

Department of Orthopaedics Surgery of Beilun People's Hospital, Ningbo, Zhejiang Province, China.

Abstract: Treatments for proximal humerus fractures (PHFs) often fail to achieve anatomical reduction. The purpose of this study was to evaluate the role of positive medial cortical support (PMCS) in the nonanatomical reduction of PHFs.A retrospective analysis was performed of 78 patients with PHFs who underwent surgery from August 2014 to September 2017 and whose treatments did not achieve anatomical reduction. Read More

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Experiences of emotional and psychosocial functioning after frontal lobe resection for epilepsy.

Epilepsy Behav 2021 Jun 1;121(Pt A):108077. Epub 2021 Jun 1.

Department of Neurology, Sahlgrenska University Hospital, SE-413 45 Göteborg, Sweden; Institute of Health and Care Sciences, Sahlgrenska Academy, University of Gothenburg, SE-413 45 Göteborg, Sweden. Electronic address:

Purpose: Frontal lobe resection (FLR) is the second most common epilepsy surgery procedure in adults. Few studies address neuropsychological consequences after FLR. The aim of this study was to explore patients' and relatives' experiences of cognitive, emotional and social cognitive functioning after frontal lobe epilepsy surgery. Read More

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Presurgical distress about bodily sensations predicts chronic postsurgical pain intensity and disability 6 months after cardiothoracic surgery.

Pain 2021 May 18. Epub 2021 May 18.

Department of Psychology, York University, Toronto, ON, Canada Department of Anesthesia and Pain Management, Toronto General Hospital, Toronto, ON, Canada Department of Anesthesiology and Pain Medicine, University of Toronto, ON, Canada Department of Anesthesia and Pain Management, St. Michael's Hospital, Toronto, ON, Canada Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada Centre for the Study of Pain, University of Toronto, Toronto, ON, Canada Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany.

Abstract: Chronic postsurgical pain (CPSP) and disability after cardiothoracic surgery are highly prevalent and difficult to treat. Researchers have explored a variety of presurgical risk factors for CPSP and disability after cardiothoracic surgery, including one study that examined distress from bodily sensations. The current prospective, longitudinal study sought to extend previous research by investigating presurgical distress about bodily sensations as a risk factor for CPSP and disability after cardiothoracic surgery while controlling for several other potential psychosocial predictors. Read More

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Structure, processes, and initial outcomes of The Ottawa Hospital Multi-Specialist Limb-Preservation Clinic and Programme: A unique-in-Canada quality improvement initiative.

Int Wound J 2021 Jun 3. Epub 2021 Jun 3.

Division of Vascular and Endovascular Surgery, Department of Surgery, University of Ottawa, Ottawa, Ontario, Canada.

In 2017, The Ottawa Hospital initiated a unique-in-Canada quality improvement initiative by opening a novel, multi-specialist limb-preservation clinic. We sought to describe the structure, processes, and initial outcomes of the clinic and evaluate whether it is achieving its mandate of providing high-quality wound clinical care, education, and research. We conducted a descriptive prospective cohort study alongside a nested study of 162 clinic patients requiring serial assessments. Read More

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Risk Factors for Kidney Stone Formation following Bariatric Surgery.

Kidney360 2020 Dec 31;1(12):1456-1461. Epub 2020 Dec 31.

Section of Nephrology, University of Chicago, Chicago, Illinois.

Kidney stones are painful, common, and increasing in incidence. Obesity and bariatric surgery rates are also on the rise in the United States. Although bariatric surgery is associated with improvements in metabolic outcomes, malabsorptive bariatric surgery procedures are also associated with increased risk of kidney stones. Read More

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December 2020