27,734 results match your criteria postoperative serum

Durable Response to Immunotherapy With Antiangiogenic Drug in Large-Cell Lung Carcinoma With Multiple Fulminant Postoperative Metastases: A Case Report.

Front Oncol 2021 20;11:633446. Epub 2021 May 20.

Department of Thoracic Surgery, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Immunotherapy alone or chemo-immunotherapy has recently been recommended for treating advanced lung carcinoma in patients without driver mutations. However, the efficacy of immunotherapy and molecular mechanism in large-cell lung cancer (LCLC) remains unclear. Here, we reported a rare case of multiple fulminant postoperative body and mouth metastases in LCLC treating with combination immunotherapy. Read More

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Perioperative Outcomes of Patients Who Were Not Candidates for Additional Nonsteroidal Anti-inflammatory Drugs in a Multimodal Pain Control Regimen for Total Knee Arthroplasty.

Clin Orthop Surg 2021 Jun 21;13(2):160-167. Epub 2020 Dec 21.

Department of Preventive and Social Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Backgroud: Postoperative pain following total knee arthroplasty (TKA) may hamper patients from a rapid recovery and increase perioperative blood loss and stress on the cardiovascular system. Therefore, our objective was to assess perioperative outcomes after TKA in patients who were not candidates for the additional nonsteroidal anti-inflammatory drugs (NSAIDs) in a multimodal pain control regimen.

Methods: Propensity score matching for age, sex, body mass index, American Society of Anesthesiologists class, and preoperative hemoglobin level was conducted on patients undergoing unilateral TKA, and thereby 52 patients remained in each group. Read More

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Diagnostic timing dependent characteristics of acute kidney injury following hepatectomy: a retrospective historical cohort analysis.

HPB (Oxford) 2021 May 18. Epub 2021 May 18.

Department of Gastroenterological Surgery I, Hokkaido University Hospital, N14, W5, Kita-ku, Sapporo, 060-8648, Japan.

Background: The timing of diagnosis of post-hepatectomy acute kidney injury (AKI) has rarely been investigated. The aim of this retrospective study was to reveal the differences between AKI subtypes following hepatectomy, as classified by timing of diagnosis.

Method: Post-hepatectomy AKI was classified as very transient AKI (vtAKI; criteria satisfied by the serum creatinine value immediately after surgery) or non-transient AKI (ntAKI; all other AKI types except for vtAKI). Read More

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Postoperative day 1 combination of serum C-reactive protein and drain amylase values predicts risks of clinically relevant pancreatic fistula. The "90-1000" score.

Surgery 2021 Jun 3. Epub 2021 Jun 3.

Department of Surgical Oncology, Institut Paoli-Calmettes, Aix-Marseille University, Marseille, France.

Background: Several scoring systems predict risks of clinically relevant postoperative pancreatic fistula after pancreatectomy, but none have emerged as the gold standard. This study aimed to evaluate the accuracy of postoperative day 1 drain amylase and serum C-reactive protein levels in predicting clinically relevant postoperative pancreatic fistula compared with intraoperative pancreatic characteristics.

Methods: Patients who underwent pancreatectomy between 2017 and 2019 were included prospectively. Read More

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A novel case of impaired C-reactive protein response following open-heart surgery: a case report and review of the literature.

Clin Chim Acta 2021 Jun 3. Epub 2021 Jun 3.

Department of Medical Biochemistry and Pharmacology, Haukeland University Hospital, Bergen, Norway; Department of Clinical Science, Faculty of Medicine, University of Bergen, Bergen, Norway.

Background: C-reactive protein (CRP) is expected to increase in response to a range of inflammatory stimuli such as infections or extensive tissue trauma.

Case Report: We present a novel case of severely impaired CRP response following NSTEMI, influenza A infection and open-heart surgery in which serum CRP concentrations remained < 1 mg/L during an observational period of 28 days.

Conclusion: To our knowledge, no previous publications exists describing patients with a lack of CRP response following cardiothoracic surgery. Read More

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Diagnosis of malignant versus tuberculous ascites using tumor markers and globulin ratios in serum and ascites: A Fisher discriminant model.

Arab J Gastroenterol 2021 Jun 2. Epub 2021 Jun 2.

Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, China. Electronic address:

Background And Study Aims: This study was conducted to investigate the significance of tumor and biochemical markers in serum and ascitic fluid in the differential diagnosis of tuberculous and malignant ascites.

Patients And Methods: Based on findings from natural orifice transluminal endoscopic surgery and postoperative pathology or cytology of 63 patients, they were divided into the malignant group (31 patients) and the tuberculous group (32 patients). Levels of tumor markers, albumin, globulin, and lactate dehydrogenase were measured simultaneously. Read More

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The effect of N-acetyl cysteine injection on renal function after coronary artery bypass graft surgery: a randomized double blind clinical trial.

J Cardiothorac Surg 2021 Jun 5;16(1):161. Epub 2021 Jun 5.

Department of Internal Medicine, School of Medicine. Chronic Renal Failure Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Background: This study aimed to compare the effects of N-acetyl cysteine on renal function after coronary artery bypass graft surgery.

Methods: In this randomized clinical trial conducted in Golestan Hospital, Ahvaz, Iran, 60 candidates for coronary artery bypass graft surgery were selected and divided into two N-acetyl cysteine and control groups (30 people each). Patients received 3 (2 intraoperative and 1 postoperative) doses of IV N-acetyl cysteine (100 mg/kg) (n = 30) or placebo (n = 30) over 24 h. Read More

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Risks and prediction of postoperative hypoparathyroidism due to thyroid surgery.

Sci Rep 2021 Jun 4;11(1):11876. Epub 2021 Jun 4.

Department of General Surgery, Yıldırım Beyazıt University School of Medicine, Çankaya, Ankara, Turkey.

We aimed to investigate the prevalence of postoperative hypoparathyroidism (PoH), the relevant factors, and predictors of transient or permanent hypoparathyroidism. The files of 352 patients who underwent bilateral total thyroidectomy alone or with central lymph node dissection and/or lateral neck dissection between June 1, 2019, and November 30, 2019, were retrospectively evaluated. Also, calcium and parathyroid hormone levels measured preoperatively and 4-6 h after surgery, follow-up examination results, and time to resolution of transient PoH were recorded. Read More

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The Natural Course of Serum D-Dimer, C-Reactive Protein, and Erythrocyte Sedimentation Rate Levels After Uneventful Primary Total Joint Arthroplasty.

J Arthroplasty 2021 Apr 30. Epub 2021 Apr 30.

Rothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA.

Background: This study aimed to assess the baseline levels of D-dimer, C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR) and monitor the natural course of these serum markers after uneventful primary total joint arthroplasty.

Methods: This prospective study enrolled 81 patients undergoing primary total knee arthroplasty or total hip arthroplasty. The level of serum D-dimer, CRP, and ESR was measured preoperatively and on postoperative days 1, 3, 5, 15, and 45. Read More

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Multiple endocrine neoplasia 2A with RET mutation p.Cys611Tyr: A case report.

Medicine (Baltimore) 2021 Jun;100(22):e26230

Department of Endocrinology and Metabolism, Longgang District People's Hospital of Shenzhen, The Third Affiliated Hospital (Provisional) of The Chinese University of Hong Kong, Longgang central city, Shenzhen, Guangdong, P.R. China.

Rationale: Multiple endocrine neoplasia 2A (MEN2A) is a rare autosomal-dominant genetic syndrome, frequently misdiagnosed or neglected clinically, resulting in delayed therapy to patients.

Patient Concerns: A 47-year-old Chinese male patient underwent laparoscopic right adrenal tumorectomy, and postoperative pathology confirmed the tumor as pheochromocytoma (PHEO). He was readmitted to the department of endocrinology and metabolism due to constant increase in carcinoembryonic antigen (CEA) at 5 months after the operation. Read More

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The risk factors of postoperative delirium in general anesthesia patients with hip fracture: Attention needed.

Medicine (Baltimore) 2021 Jun;100(22):e26156

Department of Emergency.

Abstract: Delirium is a common postoperative complication of patients with hip fracture, yet the risk factors for postoperative delirium in patients with hip fracture remain unclear. We aimed to evaluate the associated risk factors of postoperative delirium in patients with hip fracture, to provide evidence for formulating coping measures of postoperative delirium prevention and treatment in clinical practice.Patients undergoing surgery for hip fracture from March 1, 2018 to September 30, 2020 in our hospital were included. Read More

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Intraoperative Factors Associated With Early Recipient Death After Adult-to-Adult Living Donor Liver Transplant.

Exp Clin Transplant 2021 Jun 3. Epub 2021 Jun 3.

From the Department of Surgery, Great Western Hospitals NHS Foundation Trust, Swindon, United Kingdom.

Objectives: Living donor liver transplant is the gold standard therapy for patients with terminal hepatic disorders for whom no alternative therapy is available. The primary aim was to assess different intraoperative factors that may predict early death after adult-to-adult living donor liver transplant. The secondary aim was to assess the effect of small-for-size syndrome on mortality. Read More

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[Effect of electroacupuncture at Neiguan (PC 6) on pulmonary function during one-lung ventilation in patients with lobectomy].

Zhongguo Zhen Jiu 2021 Jun;41(6):598-602

Department of Anesthesiology, First Affiliated Hospital of Guangxi University of CM, Nanning 530023, China.

Objective: To observe the protective effect of electroacupuncture (EA) at Neiguan (PC 6) on pulmonary function during one-lung ventilation (OLV) in patients with lobectomy, and explore its action mechanism.

Methods: Sixty patients with lobectomy were randomly divided into an observation group and a control group, 30 cases in each one. The patients in the control group were treated with general anesthesia, and OLV was given when surgery began; when the surgery finished, air was removed from the thoracic cavity and two-lung ventilation was performed. Read More

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Serum C-reactive protein in dogs with paraplegia secondary to acute intervertebral disc extrusion.

J Vet Intern Med 2021 Jun 3. Epub 2021 Jun 3.

Dick White Referrals, Cambs, United Kingdom.

Background: Apart from the absence of nociception, there is no readily available prognostic test for dogs presenting with paraplegia secondary to acute intervertebral disc extrusion (IVDE).

Objective: To assess if serum C-reactive protein (CRP) can predict the postoperative outcome in paraplegic dogs undergoing surgery for IVDE and to assess the association between serum CRP and presence/absence of nociception on admission, and serum CRP and presence/absence of intramedullary changes seen on magnetic resonance imaging (MRI).

Animals: One hundred dogs that underwent surgery at our hospital between 2018 and 2020 because of acute paraplegia secondary to IVDE and in which serum CRP was measured. Read More

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Effect of Laparoscopic Ovarian Cystectomy on Ovarian Reserve in Benign Ovarian Cysts.

J Hum Reprod Sci 2021 Jan-Mar;14(1):56-60. Epub 2021 Mar 30.

Department of Biochemistry, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

Background: Laparoscopic cystectomy is one of the common modes of treatment for benign ovarian cysts. The data related to the effect of cystectomy on ovarian reserve are limited.

Aim: The aim of this study was to investigate the effect of laparoscopic ovarian cystectomy on anti-Mullerian hormone (AMH) levels in benign ovarian cysts. Read More

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Determination of calcium and parathyroid hormone levels following hemithyroidectomy.

Thyroid Res 2021 Jun 3;14(1):13. Epub 2021 Jun 3.

Universidad Católica de Valencia San Vicente Mártir, Valencia, Spain.

Background And Objective: Hypocalcemia is one of the main complications of thyroid surgery. We hypothesized that hemithyroidectomy may have an impact on serum parathyroid hormone (PTH) and calcium levels despite only one thyroid lobe is manipulated. The objective of this study was to analyze changes in serum PTH and calcium levels following hemithyroidectomy. Read More

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Analysis of frequency and risk factors for complications of enteral nutrition in children in Poland after percutaneous endoscopic gastrostomy placement.

Nutrition 2021 Apr 15;89:111265. Epub 2021 Apr 15.

Department of Gastroenterology, Hepatology, Feeding Disorders and Pediatrics, The Children's Memorial Health Institute, Warsaw, Poland.

Objectives: The aim of the study was to assess the complication rate and identify whether age, nutritional status, and history of respiratory aspiration prior to percutaneous endoscopic gastrostomy (PEG) are risk factors for post-PEG placement complications in Polish children. In addition, the safety of two enteral feeding methods (3 h vs. 8 h) after PEG insertion in children was compared. Read More

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Cryopreserved Rat Thyroid Autotransplantation in the Treatment of Postoperative Hypothyroidism.

Front Endocrinol (Lausanne) 2021 17;12:625173. Epub 2021 May 17.

Post Graduate Program in Surgical Sciences, Center of Experimental Surgery, Department of Surgery, School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

To verify the viability and functionality of cryopreserved thyroid autotransplantation in rats who underwent total thyroidectomy in the treatment of postoperative hypothyroidism. Thirty-two Wistar rats were randomly assigned into groups (G) with eight animals each: control (CG); simulation (SG); hypothyroidism (HTG) and transplanted (TG). At the beginning and in the 13th week of the experiment, serum levels of total T3, free T4, TSH and calcium were determined. Read More

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Ferric Carboxymaltose for Anemic Perioperative Populations: A Systematic Literature Review of Randomized Controlled Trials.

J Blood Med 2021 26;12:337-359. Epub 2021 May 26.

American Regent, Inc, Norristown, PA, USA.

Importance: Perioperative anemia is a common comorbid condition associated with increased risk of morbidity and mortality in patients undergoing elective surgical procedures.

Objective: We conducted a systematic literature review (SLR) to determine the efficacy and safety of the use of intravenous ferric carboxymaltose (FCM) for the treatment of perioperative anemia in preoperative, intraoperative, and postoperative elective surgical care.

Evidence Review: Studies meeting inclusion criteria for the SLR reported on treatment efficacy in an adult study population randomly allocated to FCM for the treatment of perioperative anemia during the perioperative period. Read More

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Temporary Ligation of the Bilateral Uterine Arteries During Laparoscopy Combined with Hysteroscopy in the Treatment of Caesarean Scar Pregnancy: Experience at a Chinese Teaching Hospital.

Int J Gen Med 2021 26;14:2087-2094. Epub 2021 May 26.

Department of Gynecology, Women and Children's Hospital, School of Medicine, Xiamen University, Xiamen, 361000, People's Republic of China.

Purpose: This study aimed to investigate the clinical efficacy of temporary ligation of the bilateral uterine arteries during laparoscopy combined with hysteroscopy in the treatment of caesarean scar pregnancy (CSP).

Patients And Methods: This study was a retrospective analysis of 83 patients who had initially undergone laparoscopy combined with hysteroscopy for CSP between 2012 and 2018 at Xiamen Women and Children's Hospital. Patients were assigned to the ligation group or the no ligation group according to whether they underwent temporary ligation of the bilateral uterine arteries. Read More

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Serum S100 calcium-binding protein A4 as a novel predictive marker of acute exacerbation of interstitial pneumonia after surgery for lung cancer.

BMC Pulm Med 2021 Jun 2;21(1):186. Epub 2021 Jun 2.

Department of Surgical Oncology, Hiroshima University, 1-2-3, Kasumi, Hiroshima, 734-8551, Japan.

Background: Acute exacerbation (AE) of interstitial pneumonia (IP) is the most fatal complication after lung resection for lung cancer. To improve the prognosis of lung cancer with IP, the risk factors of AE of IP after lung resection should be assessed. S100 calcium-binding protein A4 (S100A4) is a member of the S100 family of proteins and is a known marker of tissue fibrosis. Read More

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Thoracoscopic radical resection in the treatment of NSCLC patients (stage IIIA) after neoadjuvant chemotherapy.

J BUON 2021 Mar-Apr;26(2):313-319

Department of Oncology, Binzhou People's Hospital, Binzhou 256610, China.

Purpose: We aimed to investigate the efficacy and safety of thoracoscopic radical resection of lung cancer in the treatment of patients with stage IIIA non-small cell lung cancer (NSCLC) after neoadjuvant chemotherapy.

Methods: A total of 132 NSCLC patients (stage IIIA) were collected. Among them, 66 received preoperative neoadjuvant chemotherapy and thoracoscopic radical resection of lung cancer (NACT group), and 66 underwent thoracoscopic radical resection of lung cancer directly (control group). Read More

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Percutaneous nephrolithotomy versus extracorporeal shock wave lithotripsy for renal insufficiency.

World J Urol 2021 Jun 2. Epub 2021 Jun 2.

Department of Urology, Qena University Hospital, South Valley University, Qena, Egypt.

Objective: To assess the effect and outcome of percutaneous nephrolithotomy (PNL) versus extracorporeal shock wave lithotripsy (SWL) in patients with renal insufficiency.

Patients And Methods: A prospective randomized clinical study of 104 renal insufficiency patients with renal stones (serum creatinine 2-4 mg/dl and eGFR < 60 ml/min/1.73 m more than 3 months) randomized into two groups: Group A underwent PNL; Group B underwent shock wave lithotripsy (SWL). Read More

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Phase II randomized study of preoperative calcitriol to prevent hypocalcemia following thyroidectomy.

Head Neck 2021 Jun 2. Epub 2021 Jun 2.

Department of Otolaryngology-Head and Neck Surgery, University of Virginia Health System, Charlottesville, Virginia, USA.

Background: A prospective, stratified, randomized, double-blind, placebo-controlled study was conducted to observe the impact of preoperative calcitriol supplementation on serum calcium levels following total thyroidectomy.

Methods: Subjects were randomized 1:1 to receive 1 μg calcitriol or placebo for 1 week preceding thyroidectomy. The primary outcome measure was change in serum calcium from baseline to 18 h post-thyroidectomy. Read More

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Technique for Reduced Trocar Decapsulation of a Giant Nonparasitic Splenic Cyst.

Surg Laparosc Endosc Percutan Tech 2021 Jun 10. Epub 2021 Jun 10.

International School Reduced Scar Laparoscopy, Brussels, Belgium.

Background: Minimally invasive surgery is adopted for patients presenting benign splenic cysts. Reduced port laparoscopy is an evolution of conventional laparoscopy, which can be applied for splenic cysts as well. In this video, a 3-trocar laparoscopic decapsulation of a giant nonparasitic splenic cyst is reported. Read More

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Perioperative Nutritional Aspects in Total Pancreatectomy: A Comprehensive Review of the Literature.

Nutrients 2021 May 22;13(6). Epub 2021 May 22.

General Surgery Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Via Paradisa 2, 56124 Pisa, Italy.

Total pancreatectomy (TP) is a highly invasive procedure often performed in patients affected by anorexia, malabsorption, cachexia, and malnutrition, which are risk factors for bad surgical outcome and even may cause enhanced toxicity to chemo-radiotherapy. The role of nutritional therapies and the association between nutritional aspects and the outcome of patients who have undergone TP is described in some studies. The aim of this comprehensive review is to summarize the available recent evidence about the influence of nutritional factors in TP. Read More

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Developing a Novel Scoring System for Risk Stratification in Living Donor Liver Transplantation.

J Clin Med 2021 May 8;10(9). Epub 2021 May 8.

Department of Liver and Transplantation Surgery, Chang-Gung Memorial Hospital at Linkou, Taoyuan City 333, Taiwan.

Background: We aimed to develop a novel scoring system for risk stratification specific to living donor liver transplantation (LDLT) recipients, to improve the accuracy of predicting short-term outcomes.

Methods: The sequential organ failure assessment (SOFA) score at postoperative day 7 was collected and simplified by dichotomization, and these categories and other clinical factors were subjected to univariate and multivariate logistic regression analyses to select independent risks in constructing a "graft-to-recipient weight ratio (GRWR)-SOFA" scoring system.

Results: We enrolled 519 patients who underwent LDLT. Read More

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A Pilot Randomised Clinical Trial Comparing a Short-Term Perioperative Prophylaxis Regimen to a Long-Term Standard Protocol in Equine Colic Surgery.

Antibiotics (Basel) 2021 May 16;10(5). Epub 2021 May 16.

Equine Clinic: Surgery and Radiology, Freie Universität Berlin, 14163 Berlin, Germany.

Background: For surgical interventions classified as clean or clean-contaminated, including laparotomy, guidelines in human and veterinary medicine recommend a short-term perioperative antibiotic prophylaxis (PAP). In equine colic surgery, however, PAP commonly exceeds 24 h.

Objectives: The aim of this study was to compare a single-shot to a 5-day lasting PAP considering surgical site infections (SSI) and other adverse effects probably associated with the particular antimicrobial regimen. Read More

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Serum and Urine Biomarker Leucine-Rich Alpha-2 Glycoprotein 1 Differentiates Pediatric Acute Complicated and Uncomplicated Appendicitis.

Diagnostics (Basel) 2021 May 11;11(5). Epub 2021 May 11.

Department of Pediatric Surgery, Children's Clinical University Hospital, LV-1004 Riga, Latvia.

Purpose: This prospective, single-center cohort study analyzes the potential of inflammatory protein mediator leucine-rich alpha-2 glycoprotein 1 (LRG1) for the early and accurate diagnosis of acute appendicitis (AA), and differentiation of acute complicated (AcA) from uncomplicated appendicitis (AuA).

Methods: Participants were divided into the AcA, AuA, and control groups, and their serum (s-LRG1) and urine LRG1 (u-LRG1) levels were assayed preoperatively on the second and fifth postoperative days.

Results: 153 patients participated, 97 had AA. Read More

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Psoas Muscle Index Defined by Computer Tomography Predicts the Presence of Postoperative Complications in Colorectal Cancer Surgery.

Medicina (Kaunas) 2021 May 11;57(5). Epub 2021 May 11.

Surgical Clinic Mureș County Clinical Hospital, "G.E. Palade" University of Medicine, Pharmacy, Science and Technology of Târgu Mureş, 540142 Târgu Mureș, Romania.

: Sarcopenia is a recognized prognostic factor for both complications and survival in cancer patients. This study aims to analyze the relationship between sarcopenia measured by psoas muscle index on computer tomography scans and the presence of postoperative complications in colorectal cancer surgery. : In a prospective study we recorded data from 51 patients who underwent colorectal cancer surgery in the Mures County Clinical Hospital, Romania. Read More

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