J Affect Disord 2021 Jul 16;294:346-356. Epub 2021 Jul 16.
Institute for Life Course Health Research, Department of Global Health, Stellenbosch University, Cape Town, South Africa; Arizona State University, Tempe, AZ, United States; School of Nursing and Midwifery, Queens University, Belfast, United Kingdom. Electronic address:
Background: While the negative impact of peri-natal depression is well-documented in high-income countries, the long-term effects across the life course in low and middle-income countries is less clear. Children's adjustment over the first five years is examined as a function of patterns of maternal depressed mood.
Methods: Pregnant women in 24 peri-urban townships (N = 1,238) were randomized to a home-visiting intervention or standard care and reassessed five times, with high retention. Read More