Search Our Scientific Publications & Authors

Am J Ophthalmol 2021 Apr 12. Epub 2021 Apr 12.

Assistant Professor, Georgetown University Hospital MedStar Washington Hospital Center; Surgeon, Ophthalmology, Visionary Eye Doctors.

Purpose: To evaluate the association of children's daily-electronic-screen-use with severe meibomian-gland-atrophy (MGA).

Design: Retrospective cross-sectional study METHODS: Children (6-17years) presenting at clinical practice December 2016-2017 were evaluated for ≥grade 2 MGA versus age-matched-controls with insignificant atrophy (Read More

Pain Ther 2021 Apr 15. Epub 2021 Apr 15.

Department of Anesthesiology and Pain Medicine, Juntendo University Faculty of Medicine, 3-1-3 Hongo, Bunkyo-ku, Tokyo, 113-8431, Japan.

Introduction: Mirogabalin, which is a selective ligand of the αδ subunit of voltage-gated Ca channels, was recently approved in Japan for peripheral neuropathic pain. The αδ ligands, including mirogabalin and pregabalin, are associated with significant risk of adverse events (AEs) such as somnolence or dizziness, leading to poor compliance and subsequent inefficacy. Safety and efficacy data for switching patients from pregabalin to mirogabalin are scarce. Read More

Ocul Immunol Inflamm 2021 Apr 15:1-7. Epub 2021 Apr 15.

Ophthalmology Division, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.

: To analyse posterior segment optical coherence tomography (OCT) findings in ocular syphilis.: Medical records of 54 patients presenting consecutively with syphilitic uveitis were reviewed. Vitreous, retina and choroid (one eye/patient) were assessed by spectral-domain OCT on presentation (54 eyes) and after treatment (31 eyes). Read More

Acta Biomed 2021 Mar 31;92(S2):e2021009. Epub 2021 Mar 31.

"Santa Chiara" Institute, Rome (RM), Italy .

Background And Aim Of The Work: Safety in hospitals is a structural variable on which depends not only on health, but also on physical safety of patients and employees, whom are increasingly exposed to risks as a result of which they may suffer from occupational diseases and/or develop important psycho-physical consequences. The study aimed to evaluate the association between work environment and perceived burnout levels in two hospitals of Southern Italy.

Method: From March to August 2019 an observational study was carried out through a survey consisting of four sections: sociodemographic data; the Post Occupancy Evaluation (POE) questionnaire; the perception of the environment and possible causes of stress; the burnout levels perceived through the Maslach Burnout Inventory (MBI). Read More

Int Med Case Rep J 2021 7;14:219-222. Epub 2021 Apr 7.

Department of Ophthalmology, Tabuk University, Tabuk, Saudi Arabia.

Purpose: To report the poor visual outcome of ruptured globe caused by camel bites.

Observations: A 48-year-old camel caregiver presented to the emergency department after being bitten by a camel in the left side of his face. Ophthalmic examination revealed a superior scleral wound from 9 to 2 o'clock, about 6 mm from the limbus extending to the equator with prolapse of uveal and vitreous tissues, an opaque cornea, total hyphema, diffuse subconjunctival hemorrhage, and a lower lid laceration involving the lid margin and the nasolacrimal duct. Read More

Klin Monbl Augenheilkd 2021 Apr 14. Epub 2021 Apr 14.

Augenheilkunde, Universitätsklinikum des Saarlandes und Medizinische Fakultät der Universität des Saarlandes, Homburg (Saar), Germany.

Purpose: To report the indications and outcomes of penetrating keratoplasties with a graft diameter > 8.5 mm in severe corneal diseases at the Department of Ophthalmology at Saarland University Medical Centre.

Study Design: Retrospective (6 years), descriptive, and observational. Read More

PLoS One 2021 14;16(4):e0250084. Epub 2021 Apr 14.

Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.

Enterococcus faecalis are hospital-associated opportunistic pathogens and also causative agents of post-operative endophthalmitis. Patients with enterococcal endophthalmitis often have poor visual outcomes, despite appropriate antibiotic therapy. Here we investigated the genomic and phenotypic characteristics of E. Read More

Optom Vis Sci 2021 Apr;98(4):404-408

Department of R&D, Clínica Baviera, Madrid, Spain.

Significance: Keratoconus can manifest asymmetrically, affecting binocularity and becoming a refractive problem that is sometimes complex to solve. We propose a therapeutic approach for correction of keratoconus based on parallel implantation of a second intrastromal corneal ring segment (ICRS).

Purpose: This study aimed to improve the refractive status of a patient affected with advanced bilateral keratoconus using implantation of a second ICRS and a phakic intraocular lens. Read More

Am J Clin Nutr 2021 Apr 13. Epub 2021 Apr 13.

Department of Psychiatry, Stanford University, Stanford, CA, USA.

Background: Functional MRI (fMRI) tasks are increasingly being used to advance knowledge of the etiology and maintenance of obesity and eating disorders. Thus, understanding the test-retest reliability of BOLD signal contrasts from these tasks is important.

Objectives: To evaluate test-retest reliability of responses in reward-related brain regions to food receipt paradigms (palatable tastes, anticipated palatable tastes), food picture paradigms (high-calorie food pictures), a monetary reward paradigm (winning money and anticipating winning money), and a thin female model picture paradigm (thin female model pictures). Read More

Int J Med Sci 2021 3;18(9):1960-1965. Epub 2021 Mar 3.

Department of Physical Medicine and Rehabilitation, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, No. 325, Sec. 2, Cheng-Kung Road, Neihu District, Taipei, Taiwan, Republic of China.

Perineural injection therapy with 5% dextrose water (D5W) is a potential and innovative treatment with long-term efficacy for carpal tunnel syndrome (CTS). However, the prognostic factors of this management are lacking; hence, the aim of this retrospective study was to identify the prognostic factors of D5W perineural injection therapy for mild-to-moderate CTS. A total of 52 patients (52 wrists) diagnosed with mild-to-moderate CTS and treated with a single ultrasound-guided 5cc D5W perineural injection were retrospectively reviewed. Read More

J Craniovertebr Junction Spine 2021 Jan-Mar;12(1):44-53. Epub 2021 Mar 4.

Department of Neurosurgery, Terai Hospital and Research Centre, Birgunj, Nepal.

Background: Recurrent lumbar disc herniation (RLDH) is one of the major causes for failure of primary surgery. The optimal surgical treatment of RLDH remains controversial.

Aim: Retrospectively, we evaluate 135 patients and compare the clinical outcomes between fusion and nonfusion treatment of RLDH. Read More

Acta Orthop Traumatol Turc 2021 Mar;55(2):166-170

Department of orthopedic Surgery, 923nd Hospital of People's Liberation Army, Guangxi Province, China.

Objective: This study aimed to investigate the therapeutic effects of full endoscopic spine surgery on clinical and radiological outcomes in elderly patients over 70 years with lumbar spinal stenosis, without any obvious segmental instability.

Methods: A total of 47 patients (27 males, 20 females; the mean age=74.23±5. Read More

Ophthalmic Genet 2021 Apr 12:1-8. Epub 2021 Apr 12.

Ophthalmology Unit, Neurosciences, Mental Health, and Sense Organs (NESMOS) Department, Sapienza University of Rome, Faculty of Medicine and Psychology, St. Andrea Hospital, Rome, Italy.

: Diffuse choroidal hemangioma (DCH) is a benign vascular tumor that is characteristically found in the Sturge-Weber syndrome (SWS). Recent genetic discoveries demonstrate that DCH occurs sporadically from an activating mutation in at codon . Mutations in or result in dysregulation of the mitogen-activated protein kinase, which influences gene transcription and results in cellular proliferation. Read More

Perception 2021 Apr;50(4):367-378

Hospital Universitario Ramón y Cajal - IRYCIS, Spain.

The objective of this study is to study the influence of ocular variables in the perception of #thedress and to develop a logistic regression model that could help predict it. This is a cross-sectional study on 1,100 subjects. People who did not report one of the two main perceptions were excluded from the study. Read More

J Fr Ophtalmol 2021 Apr 7. Epub 2021 Apr 7.

Department of Statistics, Bursa Uludag University, School of Medicine, Bursa, Turkey.

Purpose: To assess the effect of foreign body volume on visual and anatomic outcomes in patients with a posterior segment intraocular foreign body (IOFB).

Methods: Patients were divided into three groups according to the volume of the IOFB; group 1 (n=18 eyes) with IOFBs<2mm, group 2 (n=15 eyes) with 2mm≤IOFBs<6mm, group 3 (n=18 eyes) with IOFBs≥6mm. All eyes underwent pars plana vitrectomy (PPV) for removal of the IOFB. Read More

BMC Ophthalmol 2021 Apr 10;21(1):173. Epub 2021 Apr 10.

Department of Ophthalmology, Westmead Hospital, Corner of Hawkesbury and Darcy Roads, Westmead, Sydney, NSW, 2145, Australia.

Background: To identify prognostic factors determining final visual outcome following open globe injuries.

Methods: Retrospective case series of patients presenting to Westmead Hospital, Sydney, Australia with open globe injuries from 1st January 2005 to 31st December 2017. Data collected included demographic information, ocular injury details, management and initial and final visual acuities. Read More

Can J Ophthalmol 2021 Apr 7. Epub 2021 Apr 7.

Massachusetts Eye Research and Surgery Institution, Waltham, Mass.; Ocular Immunology and Uveitis Foundation, Waltham, Mass.; Harvard Medical School, Boston, Mass.. Electronic address:

Objective: To investigate the clinical features, treatment, and visual outcome of occlusive retinal vasculitis (ORV), with a focal analysis on prognostic factors associated with poor visual outcome.

Methods: We conducted a retrospective cohort study in patients diagnosed with ORV with at least 6 months of follow-up. Demographic data, ocular features, best corrected visual acuity (BCVA), fluorescein angiography, therapy regimens, and outcomes were collected from the Massachusetts Eye Research and Surgery Institution database from 2006 to 2017. Read More

Sci Rep 2021 Apr 9;11(1):7816. Epub 2021 Apr 9.

Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka, 545-8585, Japan.

We investigated the relationship between trunk muscle mass and spinal pathologies by gender. This multicenter cross-sectional study included patients aged ≥ 30 years who visited a spinal outpatient clinic. Trunk and appendicular muscle mass were measured using bioelectrical impedance analysis. Read More

Front Psychol 2021 23;12:611630. Epub 2021 Mar 23.

VU University Amsterdam, Amsterdam, Netherlands.

We investigated, by means of the Reverse Correlation Task (RCT), visual representations of the culturally dominating group of local people held by sojourners as a function of their degree of cross-cultural adaptation. In three studies, using three different methods (reduced RCT, full RCT, conceptual replication) with three independent samples of sojourners and seven independent samples of Portuguese and US-American raters, we gathered clear evidence that poor adaptation goes along with more negative representations of locals. This indicates that sojourner adaptation is reflected, at a social-cognitive level, in the valence of outgroup representations. Read More

Clin Ophthalmol 2021 31;15:1375-1389. Epub 2021 Mar 31.

Department of Ophthalmology, Eberhard-Karls-University, Tuebingen, Germany.

Purpose: To find a reliable method to determine the wearing times of glasses in adults objectively on the basis of temperature measurements of the small-sized theramon thermosensor device (TM) from orthodontics. Furthermore, the reliability of the determined wearing times during well and poor position of spectacles was explored. To address the previously reported lack of accuracy during higher outside temperatures, this study was conducted in midsummer and autumn. Read More

Sci Rep 2021 Apr 8;11(1):7735. Epub 2021 Apr 8.

Cognitive Neuroscience Center, Department of Biomedical Sciences of Cells and Systems, University Medical Center Groningen, University of Groningen, Internal Zipcode FA32, Antonius Deusinglaan 2, 9713 AW, Groningen, The Netherlands.

Although previous studies reported a link between sleep problems and the occurrence of hallucinations, more detailed information is needed to translate this association into clinical practice. This study investigates sleep quality and its relation to prevalence, type, content, and phenomenology of hallucinations, using an online survey in a large population sample (n = 10,299). Based on community-based cluster analysis, four groups could be distinguished that differed in terms of sleep quality. Read More

BMC Pediatr 2021 Apr 8;21(1):165. Epub 2021 Apr 8.

London School of Hygiene & Tropical Medicine, International Centre for Eye Health, London, UK.

Background: To describe the pattern of comorbidities in school-aged children with cerebral palsy (CP) and to identify which, if any, were associated with poor school attendance. A cross-sectional study, using the key informant methodology, between December 2017 and July 2018 was conducted in Cross River State, Nigeria. Assessments, confirmation of CP and identification of systemic comorbidities using standard tools and questionnaires were performed. Read More

Medicine (Baltimore) 2021 Apr;100(14):e24888

Department of Ophthalmology and Visual Science, Hiroshima University Graduate School of Biomedical Sciences.

Rationale: The best treatment protocol for radiation maculopathy in children has not been determined. The purpose of this study was to determine the effect of photodynamic therapy (PDT) on radiation maculopathy.

Patient Concerns: An 11-year-old boy who was originally diagnosed with orbital rhabdomyosarcoma when he was 1 year old, in October 2008. Read More

Zhonghua Yan Ke Za Zhi 2021 Apr;57(4):299-304

Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai Vision Health Center & Shanghai Children Myopia Institute, Division of Ophthalmology Shanghai General Hospital, Shanghai Jiao Tong University, National Clinical Research Center for Eye Diseases, Shanghai 200040, China.

Atropine is a classical drug with a wide use in clinical practice. In ophthalmology, atropine can be used for cycloplegia before optometry, and the treatment of amblyopia, iridocyclitis, malignant glaucoma, etc. In recent years, the "old drugs with new application " research and application of atropine for myopia prevention and control has become a hotspot and the efficacy of atropine has been preliminarily recognized. Read More

Magn Reson Med 2021 Apr 8. Epub 2021 Apr 8.

Center for Biomedical Imaging, New York University Grossman School of Medicine, New York, NY, USA.

Purpose: The general utility of diffusion kurtosis imaging (DKI) is challenged by its poor robustness to imaging artifacts and thermal noise that often lead to implausible kurtosis values.

Theory And Methods: A robust scalar kurtosis index can be estimated from powder-averaged diffusion-weighted data. We introduce a novel DKI estimator that uses this scalar kurtosis index as a proxy for the mean kurtosis to regularize the fit. Read More

Brain 2021 Apr;144(3):848-862

Experimental Neurophysiology Unit, Institute of Experimental Neurology (INSPE), San Raffaele Scientific Institute, Milan, Italy.

Optical coherence tomography (OCT) is gaining increasing relevance in the assessment of patients with multiple sclerosis. Converging evidence point to the view that neuro-retinal changes, in eyes without acute optic neuritis, reflect inflammatory and neurodegenerative processes taking place throughout the CNS. The present study aims at exploring the usefulness of OCT as a marker of inflammation and disease burden in the earliest phases of the disease. Read More

J Nematol 2020 24;52. Epub 2020 Nov 24.

Entomology and Nematology Department, University of Florida, PO Box 110620, Gainesville, FL, 32611.

Yellow () and purple () nutsedges, and coffee senna () are common weeds in the southern USA and each have been reported as alternative hosts for plant-parasitic nematodes. Our objective was to determine the host suitability of these weeds to plant-parasitic nematodes common in Florida agriculture and turfgrass systems. The root-knot nematode (RKN) species tested included , , , , , , and . Read More

Front Oncol 2021 22;11:629166. Epub 2021 Mar 22.

Neurosurgical Oncological Unit, Department of Oncology and Hemato-Oncology, Università Degli Studi di Milano, Milano, Italy.

Objective: Giant insular tumors are commonly not amenable to complete resection and are associated with a high postoperative morbidity rate. Transcortical approach and brain mapping techniques allow to identify peri-insular functional networks and, with neurophysiological monitoring, to reduce vascular-associated insults. Cognitive functions to be mapped are still under debate, and the analysis of the functional risk of surgery is currently limited to neurological examination. Read More

J Eye Mov Res 2020 May 25;13(1). Epub 2020 May 25.

Child and Adolescent Psychiatry Department, Robert Debré Hospital, Paris, France.

: Dyslexia is a disorder found in 5-10% of school-aged children. Several studies reported visual deficits and oculomotor abnormalities in dyslexic children. The objective of our study was to examine horizontal pursuit performance in dyslexic children, despite its poor involvement in reading. Read More

BMC Neurol 2021 Apr 7;21(1):151. Epub 2021 Apr 7.

Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR.

Background: The prevalence of fatigue and sleep disturbances is high in stroke populations. Sleep quality can be targeted by interventions to alleviate fatigue following a stroke. This study aimed to determine the prevalence of fatigue and poor sleep quality, and to quantify the contribution of sleep quality to fatigue following a stroke, in chronic (≥1 year) stroke survivors. Read More