84,278 results match your criteria polarization camera

Identifying key areas of imbalanced supply and demand of ecosystem services at the urban agglomeration scale: A case study of the Fujian Delta in China.

Sci Total Environ 2021 Jun 5;791:148173. Epub 2021 Jun 5.

School of Architecture, Tianjin University, Tianjin 300072, China.

The coordinated supply and demand of ecosystem services (ESs) is important for ensuring regional sustainable development. However, research identifying key areas of imbalanced supply and demand of ESs at the urban agglomeration scale is limited. Therefore, in this study, using the Fujian Delta urban agglomeration of China as the research area, based on multi-source data, and analysis tools, such as ArcGIS, ENVI, and GeoDa, we constructed a research framework and indicator system for ESs supply and demand to determine the spatial change law, matching degree, and coupling coordination degree (CCD) of the ESs. Read More

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Biglycan in hepatorenal crosstalk Biglycan: a regulator of hepatorenal inflammation and autophagy.

Matrix Biol 2021 Jun 9. Epub 2021 Jun 9.

Institute of Pharmacology and Toxicology, Goethe University, Frankfurt, Germany. Electronic address:

Soluble biglycan, a small leucine-rich proteoglycan, plays a significant role in several pathologies as it has emerged as an extracellular matrix-derived danger-associated molecular pattern. Biglycan is released from the extracellular matrix in response to tissue injury and, as a canonical danger signal, interacts with innate immune receptor, Toll-like receptors 2 and 4, thereby triggering a sustained inflammatory response. Recent evidence indicates that biglycan acts as a molecular switch between inflammation and autophagy by a specific interaction with the Toll-like co-receptor CD14 and CD44, respectively. Read More

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NF-κB inhibitor suppresses experimental autoimmune neuritis in mice via declining macrophages polarization to M1 type.

Clin Exp Immunol 2021 Jun 12. Epub 2021 Jun 12.

Neuroscience Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.

Guillain-Barre' syndrome (GBS) is an acute inflammatory and immune-mediated demyelinating disease of peripheral nervous system (PNS). Macrophages play a central role in its animal model, experimental autoimmune neuritis (EAN), which has been well-accepted. Additionally, NF-κB inhibitors has been used to treat cancers and showed beneficial effects. Read More

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Mitochondrial DNA Heteroplasmy as an Informational Reservoir Dynamically Linked to Metabolic and Immunological Processes Associated with COVID-19 Neurological Disorders.

Cell Mol Neurobiol 2021 Jun 12. Epub 2021 Jun 12.

Center for Cognitive and Molecular Neuroscience, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.

Mitochondrial DNA (mtDNA) heteroplasmy is the dynamically determined co-expression of wild type (WT) inherited polymorphisms and collective time-dependent somatic mutations within individual mtDNA genomes. The temporal expression and distribution of cell-specific and tissue-specific mtDNA heteroplasmy in healthy individuals may be functionally associated with intracellular mitochondrial signaling pathways and nuclear DNA gene expression. The maintenance of endogenously regulated tissue-specific copy numbers of heteroplasmic mtDNA may represent a sensitive biomarker of homeostasis of mitochondrial dynamics, metabolic integrity, and immune competence. Read More

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HOXA5 induces M2 macrophage polarization to attenuate carotid atherosclerosis by activating MED1.

IUBMB Life 2021 Jun 11. Epub 2021 Jun 11.

Department of Vascular Surgery, The First Hospital of China Medical University, Shenyang, China.

Macrophage polarization is of great importance in the formation of atherosclerotic plaque. Homeobox A5 (HOXA5), one of the homeobox transcription factors, has been revealed to be closely associated with macrophage phenotype switching. This study aims to investigate the role of HOXA5 in carotid atherosclerosis (CAS). Read More

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Pseudolaric acid B ameliorates synovial inflammation and vessel formation by stabilizing PPARγ to inhibit NF-κB signalling pathway.

J Cell Mol Med 2021 Jun 11. Epub 2021 Jun 11.

Department of Immunology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.

Synovial macrophage polarization and inflammation are essential for osteoarthritis (OA) development, yet the molecular mechanisms and regulation responsible for the pathogenesis are still poorly understood. Here, we report that pseudolaric acid B (PAB) attenuated articular cartilage degeneration and synovitis during OA. PAB, a diterpene acid, specifically inhibited NF-κB signalling and reduced the production of pro-inflammatory cytokines, which further decreased M1 polarization and vessel formation. Read More

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Malus-metasurface-assisted polarization multiplexing.

Light Sci Appl 2020 Jun 12;9(1):101. Epub 2020 Jun 12.

School of Physics & Astronomy, University of Birmingham, Birmingham, B15 2TT, UK.

Polarization optics plays a pivotal role in diffractive, refractive, and emerging flat optics, and has been widely employed in contemporary optical industries and daily life. Advanced polarization manipulation leads to robust control of the polarization direction of light. Nevertheless, polarization control has been studied largely independent of the phase or intensity of light. Read More

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Electrospun meshes intrinsically promote M2 polarization of microglia under hypoxia and offer protection from hypoxia-driven cell death.

Biomed Mater 2021 Jun 11. Epub 2021 Jun 11.

Department of Chemical Engineering, Indian Institute of Technology Hyderabad, IITH Main Road, Near NH 65, Kandi, Sangareddy, Hyderabad, Telanagana, Hyderabad, 502205, INDIA.

In this study, we offer new insights into the contrasting effects of electrospun fiber orientation on microglial polarization under normoxia and hypoxia and establish for the first time, the intrinsically protective roles of electrospun meshes against hypoxia-induced microglial responses. First, resting microglia were cultured under normoxia on poly(caprolactone) (PCL) fibers possessing two distinctly different fiber orientations. Matrix-guided differences in cell shape/orientation and differentially expressed Rho GTPases (RhoA, Rac1, Cdc42) were well-correlated with the randomly oriented fibers inducing a predominantly pro-inflammatory phenotype and the aligned fibers sustaining a resting phenotype. Read More

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Out-of-plane and In-plane Ferroelectricity of Atom-thick Two-dimensional InSe.

Nanotechnology 2021 Jun 11. Epub 2021 Jun 11.

Tsinghua University, School of Materials Science and Engineering, Beijing, 100084, CHINA.

Two-dimensional (2D) ferroelectric materials are promising substitutes of three-dimensional perovskite based ferroelectric ceramic materials. Yet most studies have been focused on the construction of non-centrosymmetric 2D van der Waals materials and only a few are constructed experimentally. Herein, we experimentally demonstrate the co-existence of voltage-tunable out-of-plane (OOP) and in-plane (IP) ferroelectricity in few-layer InSe prepared by a solution-processable method and fabricate ferroelectric semiconductor channel transistors. Read More

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Circular dichroism enhancement and dynamically adjustment in planar metal chiral split rings with graphene sheets arrays.

Nanotechnology 2021 Jun 11. Epub 2021 Jun 11.

Xi'an University of Posts and Telecommunications, Xi'an University of Posts and Telecommunications, No. 618, West Chang'an Avenue, Xi'an, Shaanxi, 710121, CHINA.

Chiral plasmonic nanostructures have become a promising platform for polarization converters and molecular analysis. However, the circular dichroism (CD) of planar chiral plasmonic nanostructures is always weak and difficult for dynamic adjustment. In this work, graphene sheets (GSs) are introduced in planar metal chiral split rings (MCSRs) to enhance and dynamically adjust their CD effect. Read More

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WFDC2 promotes spasmolytic polypeptide-expressing metaplasia through the upregulation of IL33 in response to injury.

Gastroenterology 2021 Jun 8. Epub 2021 Jun 8.

Severance Biomedical Science Institute, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul 03722, Korea. Electronic address:

Background & Aims: WAP four-disulfide core domain protein 2 (WFDC2), also known as human epididymis protein 4 (HE4), is a small secretory protein that is highly expressed in fibrosis and human cancers, particularly in the ovaries, lungs, and stomach. However, the role of WFDC2 in carcinogenesis is not fully understood. The present study aimed to investigate the role of WFDC2 in gastric carcinogenesis using preneoplastic metaplasia models. Read More

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Ubiquitin Signaling in the Control of Centriole Duplication.

FEBS J 2021 Jun 11. Epub 2021 Jun 11.

School of Biology, Indian Institute of Science Education and Research, Thiruvananthapuram, Vithura, Thiruvananthapuram, 695551, Kerala, India.

Centrosome plays essential roles in maintaining genetic stability, ciliogenesis and cell polarization. The core of centrosome is made of two centrioles that duplicate precisely once during every cell cycle to generate two centrosomes that are required for bipolar spindle assembly and chromosome segregation. Abundance of centriole proteins at optimal levels and their recruitment to the centrosome are tightly regulated in time and space in order to restrict aberrant duplication of centrioles, a phenomenon that is observed in many cancers. Read More

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Dressing of Cu Atom over Nickel Cluster Stimulating the Poisoning-Free CO Oxidation: An Ab Initio Study.

J Phys Chem A 2021 Jun 11. Epub 2021 Jun 11.

Department of Physics, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara 390002, Gujarat, India.

In this work using first-principles calculations based on spin-polarized density functional theory (DFT), the role of the Cu atom in degrading the poisoning of carbon monoxide (CO) over NiCu clusters is unveiled. The search has been initiated with the examination of structural, magnetic, and electronic properties of Ni and NiCu clusters (1 ≤ ≤ 12). X-ray absorption near-edge structure (XANES) spectra of Ni K-edge are computed to extract the information on the oxidation states and coordination environment of metal sites of the clusters. Read More

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Correction: prediction of cross-effect efficiency for magic angle spinning dynamic nuclear polarization.

Phys Chem Chem Phys 2021 Jun 11. Epub 2021 Jun 11.

Univ. Grenoble Alpes, CEA, CNRS, INAC-MEM, F-38000 Grenoble, France.

Correction for 'De novo prediction of cross-effect efficiency for magic angle spinning dynamic nuclear polarization' by Frédéric Mentink-Vigier et al., Phys. Chem. Read More

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A systematic CRISPR screen reveals an IL-20/IL20RA-mediated immune crosstalk to prevent the ovarian cancer metastasis.

Elife 2021 Jun 11;10. Epub 2021 Jun 11.

The School of Medicine, Nankai University, Tianjin, China.

Transcoelomic spread of cancer cells across the peritoneal cavity occurs in most initially diagnosed ovarian cancer (OC) patients and accounts for most cancer-related death. However, how OC cells interact with peritoneal stromal cells to evade the immune surveillance remains largely unexplored. Here, through an in vivo genome-wide CRISPR/Cas9 screen, we identified IL20RA, which decreased dramatically in OC patients during peritoneal metastasis, as a key factor preventing the transcoelomic metastasis of OC. Read More

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Nuclear Spin Dynamics, Noise, Squeezing, and Entanglement in Box Model.

Phys Rev Lett 2021 May;126(21):216804

Ioffe Institute, 194021 St. Petersburg, Russia.

We obtain a compact analytical solution for the nonlinear equation for the nuclear spin dynamics in the central spin box model in the limit of many nuclear spins. The total nuclear spin component along the external magnetic field is conserved and the two perpendicular components precess or oscillate depending on the electron spin polarization, with the frequency, determined by the nuclear spin polarization. As applications of our solution, we calculate the nuclear spin noise spectrum and describe the effects of nuclear spin squeezing and many body entanglement in the absence of a system excitation. Read More

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Dielectric Constant of Liquid Water Determined with Neural Network Quantum Molecular Dynamics.

Phys Rev Lett 2021 May;126(21):216403

Collaboratory for Advanced Computing and Simulations, Department of Chemical Engineering and Materials Science, Department of Physics & Astronomy, and Department of Computer Science, University of Southern California, Los Angeles, California 90089, USA.

The static dielectric constant ϵ_{0} and its temperature dependence for liquid water is investigated using neural network quantum molecular dynamics (NNQMD). We compute the exact dielectric constant in canonical ensemble from NNQMD trajectories using fluctuations in macroscopic polarization computed from maximally localized Wannier functions (MLWF). Two deep neural networks are constructed. Read More

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Widespread Negative Longitudinal Piezoelectric Responses in Ferroelectric Crystals with Layered Structures.

Phys Rev Lett 2021 May;126(21):217601

Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, USA.

In this study, we investigate the underlying mechanisms of the universal negative piezoelectricity in low-dimensional layered materials by carrying out first-principles calculations. Two-dimensional layered ferroelectric CuInP_{2}S_{6} is analyzed in detail as a typical example, but the theory can be applied to any other low-dimensional layered piezoelectrics. Consistent with the theory proposed in [Phys. Read More

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Probing the Chiral Domains and Excitonic States in Individual WS Tubes by Second-Harmonic Generation.

Nano Lett 2021 Jun 11. Epub 2021 Jun 11.

State Key Laboratory of Surface Physics, Key Laboratory of Micro and Nano Photonic Structures (MOE), and Department of Physics, Fudan University, Shanghai 200433, People's Republic of China.

Distinct from carbon nanotubes, transition-metal dichalcogenide (TMD) nanotubes are noncentrosymmetric and polar and can exhibit some intriguing phenomena such as nonreciprocal superconductivity, chiral shift current, bulk photovoltaic effect, and exciton-polaritons. However, basic characterizations of individual TMD nanotubes are still quite limited, and much remains unclear about their structural chirality and electronic properties. Here we report an optical second-harmonic generation (SHG) study on multiwalled WS nanotubes on a single-tube level. Read More

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miR-498 inhibits autophagy and M2-like polarization of tumor-associated macrophages in esophageal cancer via MDM2/ATF3.

Epigenomics 2021 Jun 11. Epub 2021 Jun 11.

Department of Anatomy, School of Basic Medicine, North Sichuan Medical College, Nanchong, 637000, Sichuan, PR China.

Structured abstract To elucidate the effect of miRNA (miR)-498 on autophagy and M2-like macrophage polarization in esophageal cancer. Autophagy was evaluated in esophageal cancer. Macrophage markers specific for M1- or M2-like phenotype were determined. Read More

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Room-Temperature Magnetic Field Effect on Excitonic Photoluminescence in Perovskite Nanocrystals.

Adv Mater 2021 Jun 10:e2008225. Epub 2021 Jun 10.

State Key Laboratory of Materials Processing and Die & Mould Technology, School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan, Hubei, 430074, P. R. China.

Magnetic-field-enhanced spin-polarized electronic/optical properties in semiconductors are crucial for fabricating various spintronic devices. However, this spin polarization is governed by weak spin exchange interactions and easily randomized by thermal fluctuations; therefore, it is only produced at cryogenic temperatures, which severely limits the applications. Herein, a room-temperature intrinsic magnetic field effect (MFE) on excitonic photoluminescence is achieved in CsPbX :Mn (X = Cl, Br) perovskite nanocrystals. Read More

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Switchable Assembly and Guidance of Colloidal Particles on an All-Dielectric One-Dimensional Photonic Crystal.

Phys Rev Appl 2020 Jan 13;13(1). Epub 2020 Jan 13.

Advanced Laser Technology Laboratory of Anhui Province and Institute of Photonics, Department of Optics and Optical Engineering, University of Science and Technology of China, Hefei, Anhui 230026, China.

Dielectric multilayer photonic-band-gap structures, called one-dimensional photonic crystals (1DPCs), have drawn considerable attention in the fields of physics, chemistry, and biophotonics. Here, experimental results verify the feasibility of a 1DPC working as a substrate for switchable manipulations of colloidal microparticles. The optically induced thermal convective force on a 1DPC can assemble colloidal particles that are dispersed in a water solution, while the photonic scattering force on the same 1DPC caused by propagating evanescent waves can guide these particles. Read More

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January 2020

Phagocytosis and Efferocytosis by Resident Macrophages in the Mouse Pancreas.

Front Endocrinol (Lausanne) 2021 25;12:606175. Epub 2021 May 25.

Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden.

The tissue microenvironment in the mouse pancreas has been shown to promote very different polarizations of resident macrophages with islet-resident macrophages displaying an inflammatory "M1" profile and macrophages in the exocrine tissue mostly displaying an alternatively activated "M2" profile. The impact of this polarization on tissue homeostasis and diabetes development is unclear. In this study, the ability of pancreas-resident macrophages to phagocyte bacterial and endogenous debris was investigated. Read More

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Haploinsufficiency of ARFGEF1 is associated with developmental delay, intellectual disability, and epilepsy with variable expressivity.

Genet Med 2021 Jun 10. Epub 2021 Jun 10.

Inserm UMR1231 team GAD, University of Burgundy and Franche-Comté, Dijon, France.

Purpose: ADP ribosylation factor guanine nucleotide exchange factors (ARFGEFs) are a family of proteins implicated in cellular trafficking between the Golgi apparatus and the plasma membrane through vesicle formation. Among them is ARFGEF1/BIG1, a protein involved in axon elongation, neurite development, and polarization processes. ARFGEF1 has been previously suggested as a candidate gene for different types of epilepsies, although its implication in human disease has not been well characterized. Read More

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Alternative activation of macrophages by prostacyclin synthase ameliorates alcohol induced liver injury.

Lab Invest 2021 Jun 10. Epub 2021 Jun 10.

Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, 230032, China.

Alcoholic liver disease (ALD) is a major cause of chronic liver disease worldwide. Macrophages exhibit different functional states and are classified as classically activated (M1) and alternatively activated (M2) macrophages. However, the mechanisms that govern M1/M2 polarization in chronic ALD remain to be elucidated. Read More

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Large scale self-assembly of plasmonic nanoparticles on deformed graphene templates.

Sci Rep 2021 Jun 10;11(1):12232. Epub 2021 Jun 10.

Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, USA.

Hierarchical heterostructures of two-dimensional (2D) nanomaterials are versatile platforms for nanoscale optoelectronics. Further coupling of these 2D materials with plasmonic nanostructures, especially in non-close-packed morphologies, imparts new metastructural properties such as increased photosensitivity as well as spectral selectivity and range. However, the integration of plasmonic nanoparticles with 2D materials has largely been limited to lithographic patterning and/or undefined deposition of metallic structures. Read More

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Optical shaping of the polarization anisotropy in a laterally coupled quantum dot dimer.

Light Sci Appl 2020 Jun 11;9(1):100. Epub 2020 Jun 11.

Department of Physics, Pusan Nat'l University, Busan, 609-735, Republic of Korea.

We find that the emission from laterally coupled quantum dots is strongly polarized along the coupled direction [1[Formula: see text]0], and its polarization anisotropy can be shaped by changing the orientation of the polarized excitation. When the nonresonant excitation is linearly polarized perpendicular to the coupled direction [110], excitons (X and X) and local biexcitons (XX and XX) from the two separate quantum dots (QD and QD) show emission anisotropy with a small degree of polarization (10%). On the other hand, when the excitation polarization is parallel to the coupled direction [1[Formula: see text]0], the polarization anisotropy of excitons, local biexcitons, and coupled biexcitons (XX) is enhanced with a degree of polarization of 74%. Read More

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Targeting monoamine oxidase A-regulated tumor-associated macrophage polarization for cancer immunotherapy.

Nat Commun 2021 06 10;12(1):3530. Epub 2021 Jun 10.

Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA, USA.

Targeting tumor-associated macrophages (TAMs) is a promising strategy to modify the immunosuppressive tumor microenvironment and improve cancer immunotherapy. Monoamine oxidase A (MAO-A) is an enzyme best known for its function in the brain; small molecule MAO inhibitors (MAOIs) are clinically used for treating neurological disorders. Here we observe MAO-A induction in mouse and human TAMs. Read More

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Interfacial ferroelectricity by van der Waals sliding.

Science 2021 Jun 10. Epub 2021 Jun 10.

School of Physics and Astronomy, Tel Aviv University, Israel.

Despite their partial ionic nature, many layered diatomic crystals avoid internal electric polarization by forming a centrosymmetric lattice at their optimal van-der-Waals stacking. Here, we report a stable ferroelectric order emerging at the interface between two naturally-grown flakes of hexagonal-boron-nitride, which are stacked together in a metastable non-centrosymmetric parallel orientation. We observe alternating domains of inverted normal polarization, caused by a lateral shift of one lattice site between the domains. Read More

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Placental chorionic plate-derived mesenchymal stem cells ameliorate severe acute pancreatitis by regulating macrophage polarization via secreting TSG-6.

Stem Cell Res Ther 2021 Jun 10;12(1):337. Epub 2021 Jun 10.

Department of General Surgery & Pancreatic Injury and Repair Key Laboratory of Sichuan Province, The General Hospital of Western Theater Command, Chengdu, 610083, China.

Background: Mesenchymal stem cells (MSCs) hold promising potential to treat systemic inflammatory diseases including severe acute pancreatitis (SAP). In our previous study, placental chorionic plate-derived MSCs (CP-MSCs) were found to possess superior immunoregulatory capability. However, the therapeutic efficacy of CP-MSCs on SAP and their underlying mechanism remain unclear. Read More

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