32,086 results match your criteria pleural effusion

Computed tomographic features of coronavirus disease-2019 (COVID-19) pneumonia in three groups of Iranian patients: A single center study.

Radiologia 2021 Mar 14. Epub 2021 Mar 14.

Centro de Investigación de Gastroenterología y Enfermedades Hepáticas, Instituto de Investigación de Gastroenterología y Enfermedades Hepáticas, Universidad de Ciencias Médicas Shahid Beheshti, Teherán, Irán.

Introduction And Objectives: The pivotal role of chest computed tomographic (CT) to diagnosis and prognosis coronavirus disease-2019 (COVID-19) is still an open field to be explored. This study was conducted to assess the CT features in confirmed cases with COVID-19.

Materials And Methods: Retrospectively, initial chest CT data of 363 confirmed cases with COVID-19 were reviewed. Read More

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Concurrent manifestations of Horner's syndrome and esophageal metastasis of breast cancer: case report of a young woman after a period of non-adherence to treatment: a case report.

J Med Case Rep 2021 Apr 9;15(1):194. Epub 2021 Apr 9.

Division of Surgical Oncology-Department of Surgery, Dr. Sardjito Hospital/Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Jl Kesehatan No. 1, Yogyakarta, 55281, Indonesia.

Background: Esophageal involvement and Horner's syndrome are rare manifestations of breast cancer distant metastases that can pose a significant challenge in diagnosis and treatment. In addition to the more aggressive behavior of breast cancer diagnosed in young women, non-adherence to treatment is associated with increased risk of distant metastasis.

Case Presentation: A 36-year-old Javanese woman presented to our institution with dysphagia, hoarseness, and frequent hiccups. Read More

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A Case of Dapsone-induced Mild Methemoglobinemia with Dyspnea and Cyanosis.

Acta Dermatovenerol Croat 2020 Dec;28(4):249-250

Hisayoshi Imanishi, MD, PhD, Division of Dermatology, Daito Central Hospital, 2-1-11 Ono, Daito, Osaka 574-0042, Japan;

Dear Editor, Dapsone is a dual-function drug with antimicrobial and antiprotozoal effects and anti-inflammatory features (1). In dermatology, it is a first choice for conditions such as leprosy, IgA pemphigus, dermatitis herpetiformis, and linear IgA bullous dermatosis, or an adjunctive treatment for, e.g. Read More

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December 2020

A fatal invasive pulmonary infection in an adult patient with malignant lung adenocarcinoma.

Curr Med Mycol 2020 Sep;6(3):61-64

Department of Infectious Diseases and Clinical Microbiology, Kayseri City Hospital, Kayseri, Turkey.

Background And Purpose: complex as a ubiquitous environmental mold is increasingly reported to cause an invasive fungal infection in immunosuppressive hosts. Herein, we present the case of an immunosuppressive 54 - year-old man who developed complex lung infection and pulmonary adenocarcinoma.

Case Report: The patient had some complaints of dyspnea and cough during a neutropenic episode. Read More

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September 2020

Clinical Misdiagnosis of COVID-19 Infection with Confusing Clinical Course.

Case Rep Infect Dis 2021 31;2021:6629966. Epub 2021 Mar 31.

Pediatric Department, Pediatric Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.

Background: Similarities in the febrile course and other manifestations of some diseases may lead to clinical misdiagnosis of COVID-19 infection. Here, we report a case in a young child with a potentially confusing clinical course. . Read More

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Corrigendum: Previous Radiotherapy Increases the Efficacy of IL-2 in Malignant Pleural Effusion: Potential Evidence of a Radio-Memory Effect?

Front Immunol 2021 23;12:649620. Epub 2021 Mar 23.

Department of Radiation Oncology, Shandong Cancer Hospital affiliated to Shandong University, Jinan, China.

[This corrects the article DOI: 10.3389/fimmu.2018. Read More

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Clinical Features and Prognosis of Nontuberculous Mycobacterial Pleuritis: A Multicenter Retrospective Study.

Ann Am Thorac Soc 2021 Apr 8. Epub 2021 Apr 8.

Keio University School of Medicine, Department of Infectious Diseases, Shinjuku-ku, Tokyo, Japan;

Rationale: The clinical features and prognosis of nontuberculous mycobacterial (NTM) pleuritis and pleural effusion combined with NTM lung disease (NTM-LD) remain unclear.

Objectives: To investigate the clinical features and prognosis of NTM pleuritis.

Methods: This retrospective observational study included patients with NTM pleuritis from January 2001 to June 2018 across eight hospitals in Japan. Read More

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[Descending Necrotizing Mediastinitis with Empyema Necessitated Two Performances of Surgical Drainage for Successful Treatment:Report of a Case].

Kyobu Geka 2021 Apr;74(4):313-316

Department of Surgery, Kagawa Prefectural Shirotori Hospital, Higashikagawa, Japan.

The case was a 57-year-old woman. She visited a local doctor with a chief complaint of sore throat. A retropharyngeal abscess was suspected, and she was referred to our otolaryngology. Read More

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The incidence of pleural effusion in COVID-19 pneumonia: State-of-the-art review.

Heart Lung 2021 Feb 27;50(4):481-490. Epub 2021 Feb 27.

Department of Pulmonary and Critical Care Medicine, Albany Medical Center, Albany, NY, USA.

Background: COVID-19-related pleural effusions are frequently described during the ongoing pandemic.

Objectives: We described the incidence, characteristics, and outcomes of COVID-19-related pleural effusions based on the current evidence available in the literature.

Methods: We searched MEDLINE, Pubmed, and Google Scholar databases using keywords of "coronavirus disease 2019 (COVID-19)," "severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)," "pleural effusion," "pleural fluid," and "pleura" from January 1st, 2020 to January 31st, 2021. Read More

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February 2021

A novel osimertinib-resistant human lung adenocarcinoma cell line harbouring mutant EGFR and activated IGF1R.

Jpn J Clin Oncol 2021 Apr 7. Epub 2021 Apr 7.

Allergy and Respiratory Medicine, Okayama University Hospital, Okayama, Japan.

Objective: A third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), osimertinib, is the standard treatment for patients with non-small cell lung cancer harbouring mutant EGFR. Unfortunately, these patients inevitably acquire resistance to EGFR-TKI therapies, including osimertinib. However, the mechanism associated with this resistance remains unclear. Read More

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Shock and Diffuse ST-elevation in a Patient with Coronavirus Disease-2019 Disease.

J Cardiovasc Echogr 2020 Oct-Dec;30(4):223-226. Epub 2021 Jan 20.

Department of Medicine, Vascular and Emergency Medicine - Stroke Unit, University of Perugia, Perugia, Italy.

The infection by the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is associated with significant cardiovascular morbidity and mortality. Cardiac events require prompt diagnosis and management, also in the SARS-CoV-2 era. A 58-year-old male, heavy smoker and with known SARS-CoV-2 infection, abruptly developed severe hypotension and asthenia. Read More

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January 2021

A 5G-powered robot-assisted teleultrasound diagnostic system in an intensive care unit.

Crit Care 2021 04 7;25(1):134. Epub 2021 Apr 7.

Henan Provincial People's Hospital, Zhengzhou University People's Hospital, No. 7, Weiwu Road, Jinshui District, Zhengzhou, 450003, Henan, China.

Background: Teleultrasound provides an effective solution to problems that arise from limited medical resources, a lack of local expertise, and scenarios where the risk of infection is high. This study aims to explore the feasibility of the application of a 5G-powered robot-assisted teleultrasound diagnostic system in an intensive care unit.

Methods: In this study, the robot-assisted teleultrasound diagnostic system MGIUS-R3 was used. Read More

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Image-guided microwave ablation of hepatocellular carcinoma (≤5.0 cm): is MR guidance more effective than CT guidance?

BMC Cancer 2021 Apr 7;21(1):366. Epub 2021 Apr 7.

Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou City, 450000, Henan Province, China.

Background: Given their widespread availability and relatively low cost, percutaneous thermal ablation is commonly performed under the guidance of computed tomography (CT) or ultrasound (US). However, such imaging modalities may be restricted due to insufficient image contrast and limited tumor visibility, which results in imperfect intraoperative treatment or an increased risk of damage to critical anatomical structures. Currently, magnetic resonance (MR) guidance has been proven to be a possible solution to overcome the above shortcomings, as it provides more reliable visualization of the target tumor and allows for multiplanar capabilities, making it the modality of choice. Read More

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Deep-Learning-Based Diagnosis of Bedside Chest X-ray in Intensive Care and Emergency Medicine.

Invest Radiol 2021 Mar 5. Epub 2021 Mar 5.

From the Department of Radiology, Charité, Berlin Department of Radiology, Berlin Institute of Health (BIH), Charité, Berlin Institute of Oral and Maxillofacial Surgery, Charité, Berlin Department of Diagnostic and Interventional Radiology, Technical Universtity of Munich, School of Medicine, Munich, Germany.

Objectives: Validation of deep learning models should separately consider bedside chest radiographs (CXRs) as they are the most challenging to interpret, while at the same time the resulting diagnoses are important for managing critically ill patients. Therefore, we aimed to develop and evaluate deep learning models for the identification of clinically relevant abnormalities in bedside CXRs, using reference standards established by computed tomography (CT) and multiple radiologists.

Materials And Methods: In this retrospective study, a dataset consisting of 18,361 bedside CXRs of patients treated at a level 1 medical center between January 2009 and March 2019 was used. Read More

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Pleural and Pericardial Infection Due to Cutibacterium acnes in a Splenectomized Patient: A Case Report of an Underreported Systemic Infection.

Cureus 2021 Mar 3;13(3):e13668. Epub 2021 Mar 3.

Infectious Disease, Piedmont Athens Regional Medical Center, Athens, USA.

Infectious pericarditis does not always present with all the classic findings. Some of the traditional signs of fever, pleuritic chest pain, and frictional rub may be missing. This presents a diagnostic challenge, thus clinical suspicion is important. Read More

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Rovalpituzumab Tesirine as a Maintenance Therapy Following First-Line Platinum-Based Chemotherapy in Patients With Extensive-Stage Small Cell Lung Cancer: Results From the Phase 3 MERU Study.

J Thorac Oncol 2021 Apr 3. Epub 2021 Apr 3.

Sheba Medical Center, Ramat Gan, Israel, and Sackler Medical School, Tel-Aviv University, Tel-Aviv, Israel.

Introduction: Rovalpituzumab tesirine (Rova-T) is an antibody-drug conjugate targeting delta-like protein 3 (DLL3), an atypical Notch ligand expressed in small cell lung cancer (SCLC) tumors. We evaluated the efficacy of Rova-T versus placebo as maintenance therapy in patients with extensive stage (ES) SCLC after platinum-based chemotherapy.

Methods: MERU was a phase 3 randomized, double-blinded, placebo-controlled study. Read More

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Rapid quantification of COVID-19 pneumonia burden from computed tomography with convolutional LSTM networks.

ArXiv 2021 Mar 31. Epub 2021 Mar 31.

Quantitative lung measures derived from computed tomography (CT) have been demonstrated to improve prognostication in coronavirus disease (COVID-19) patients, but are not part of the clinical routine since required manual segmentation of lung lesions is prohibitively time-consuming. We propose a new fully automated deep learning framework for rapid quantification and differentiation between lung lesions in COVID-19 pneumonia from both contrast and non-contrast CT images using convolutional Long Short-Term Memory (ConvLSTM) networks. Utilizing the expert annotations, model training was performed 5 times with separate hold-out sets using 5-fold cross-validation to segment ground-glass opacity and high opacity (including consolidation and pleural effusion). Read More

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Clinical characteristics of COVID-19 patients with clinically diagnosed bacterial co-infection: A multi-center study.

PLoS One 2021 5;16(4):e0249668. Epub 2021 Apr 5.

Department of Respiratory and Critical Care Medicine, The Third Xiangya Hospital of Central South University, Hunan, China.

Objective: To understand the clinical characteristics of COVID-19 patients with clinically diagnosed bacterial co-infection (CDBC), and therefore contributing to their early identification and prognosis estimation.

Method: 905 COVID-19 patients from 7 different centers were enrolled. The demography data, clinical manifestations, laboratory results, and treatments were collected accordingly for further analyses. Read More

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Spondylodiscitis presenting as pleural effusion in a geriatric female: A case report.

J Pak Med Assoc 2021 02;71(2(A)):543-546

Yedikule Chest Disease and Surgery Education and Research Hospital, Istanbul, Turkey.

Pleural effusion is a frequently seen medical problem caused by pulmonary and non-pulmonary diseases. Spondylodiscitis is a very rare cause of pleural effusion and is typically diagnosed based on clinical, laboratory, microbiological and radiological findings. The low incidence and different clinical presentations of Spondylodiscitis make its diagnosis and treatment challenging. Read More

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February 2021

Diagnostic accuracy of the cancer ratio for the prediction of malignant pleural effusion: evidence from a validation study and meta-analysis.

Ann Med 2021 Dec;53(1):558-566

Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China.

Objective: This study aimed to assess the diagnostic accuracy of serum LDH to pleural ADA ratio (cancer ratio, CR)for malignant pleural effusion (MPE) through an original study and meta-analysis.

Methods: We retrospectively collected data from 145 patients with MPE and 117 cases of benign pleural effusions (BPE). The diagnostic performance of CR and a typical biomarker of MPE, carcinoembryonic antigen (CEA), were analysed using the receiver operating characteristic (ROC) curves and the area under the curve (AUC) as a measure of accuracy. Read More

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December 2021

Comparison of clinical manifestation among Australian Indigenous and non- Indigenous patients presenting with pleural effusion.

Intern Med J 2021 Apr 5. Epub 2021 Apr 5.

College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.

Background: There is sparse evidence in the literature in relation to the nature and causes of pleural effusion among Australian Indigenous population.

Methods: In this retrospective study, Indigenous and non-Indigenous adults diagnosed to have pleural effusion over a two-year study period were included for comparative analysis.

Results: Of the 314 patients, 205 (65%) were non-Indigenous and 52% were males. Read More

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Diagnostic Accuracy of Pleural Effusion Mononuclear Cells/Leukocyte Ratio in Tuberculous Pleurisy.

Front Med (Lausanne) 2021 18;8:639061. Epub 2021 Mar 18.

Department of Pulmonary and Critical Care Medicine, Henan Provincial People's Hospital, Zhengzhou, China.

Tuberculous pleurisy (TBP) is a common clinical type of tuberculosis (TB) in China. TBP is difficult to diagnose. Whether the mononuclear cell/leukocyte (MNC/LEU) ratio in pleural effusion can contribute to accurate TBP diagnosis remains yet unclear. Read More

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A case of Sjögren's syndrome with worsening of pleural effusion due to steroid discontinuation.

Osamu Usami

Respir Med Case Rep 2021 19;33:101391. Epub 2021 Mar 19.

Kurihara Central Hospital, Department of Respiratory Medicine, Miyano Cyuo 3-11, Tsukidate, Kurihara, Miyagi, 987-2205, Japan.

The etiology of Sjögren's syndrome (SS) remains unclear and is associated with many other autoimmune diseases. In particular, symptoms of SS are not apparent when steroids are already being administered for other autoimmune diseases. This report documents a case of autoimmune hepatitis with SS, which was diagnosed on the basis of the worsening of unilateral pleural effusion after the discontinuation of steroids as well as the manifestation of symptoms, such as dry mouth. Read More

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Recurrent Large Volume Malignant Pleural Effusion in a Patient With Renal Cell Carcinoma.

Cureus 2021 Feb 27;13(2):e13593. Epub 2021 Feb 27.

Internal Medicine, NewYork-Presbyterian Brooklyn Methodist Hospital, Brooklyn, USA.

Malignant pleural effusion (MPE) due to renal cell carcinoma (RCC) is extremely rare, accounting for only 1%-2% of all malignant pleural effusions. This paper presents a case report of a 56-year-old male who presented with a chief complaint of bilateral flank pain with dyspnea and was diagnosed with RCC via immunopathologic pleural fluid analysis and who persistently had recurrent large volume pleural effusion. A 56-year-old male who had a recent admission for dyspnea secondary to a right-sided pleural effusion underwent thoracentesis and returned to the hospital for his worsening shortness of breath. Read More

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February 2021

A 6-Year-Old Boy with COVID-19-Positive Pleural Effusion and Kawasaki-Like Features.

Case Rep Pediatr 2021 17;2021:8832826. Epub 2021 Mar 17.

Department of Pediatrics, Ali Asghar Children's Hospital, Iran University of Medical Sciences, Tehran, Iran.

The ongoing outbreak of the novel coronavirus (SARS-CoV-2) has exposed many pediatric patients from around the world to coronavirus disease. Although pleural effusions are classified as atypical features of COVID-19 infection, we report a 6-year-old boy who had a positive IgG antibody ELISA test for COVID-19 and presented with respiratory distress, bilateral pleural effusions, and signs and symptoms of multisystem inflammatory syndrome. The RT-PCR test of the pleural fluid specimen was positive for novel coronavirus. Read More

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Hemorrhagic Malignant Pleural Effusion: Diagnosis, Survival Rate, and Response to Talc Pleurodesis.

Indian J Surg Oncol 2021 Mar 14;12(1):54-60. Epub 2020 Nov 14.

Department of Thoracic Surgery, western Galilee medical center, Nahariya, Israel.

Hemorrhagic malignant pleural effusion (HMPE) is diagnosed in 47-50% of all malignant pleural effusions (MPE). The aim of this study is to evaluate clinical, radiological, and morphological manifestations of HMPE and results of talc pleurodesis treatment. This is a retrospective review of the medical charts of 135 MPE patients which consists of HMPE group (42 patients) and simple MPE group (63 patients) (median age 67. Read More

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Spectrum of chest CT manifestations of coronavirus disease (COVID-19): A pictorial essay.

Indian J Radiol Imaging 2021 Jan 23;31(Suppl 1):S170-S177. Epub 2021 Jan 23.

Department of Radiodiagnosis, Government Medical College, Srinagar, Jammu and Kashmir, India.

Coronavirus disease (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is an enveloped single-stranded RNA virus belonging to the family of betacoronaviruses. Chest computed tomography (CT) has helped us in understanding this new disease. Typical CT features of COVID-19 pneumonia are ground-glass opacities (GGO), crazy paving pattern and GGO with superimposed consolidation with a basal, posterior and peripheral lung predilection. Read More

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January 2021

Role of portable chest radiography in management of COVID-19: Experience of 422 patients from a tertiary care center in India.

Indian J Radiol Imaging 2021 Jan 23;31(Suppl 1):S94-S100. Epub 2021 Jan 23.

Department of Medicine, SMS Medical College and Hospital, Jaipur, Rajsthan, India.

Objective: To analyze radiological changes in portable chest radiographs in coronavirus disease-19(COVID-19) patients to optimize the management of hospitalized patients.

Methods: We retrospectively reviewed 638 portable radiographs of 422 hospitalized COVID-19 patients with RT-PCR confirmed COVID-19 infection. All the radiographs were reported in a structured format by two experienced radiologists. Read More

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January 2021

Thoracic Multidetector Computed Tomography Evaluation of Inflammatory Myofibroblastic Tumor of the Lung in Pediatric Patients in the Era of Modern Diagnosis.

J Thorac Imaging 2021 Apr 2. Epub 2021 Apr 2.

Departments of Radiology Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA Department of Pediatric Radiology, Clinical Radiology Institute, University Medical Centre Ljubljana, Ljubljana, Slovenia Department of Radiology, College of Medicine and Health Sciences, Al Ain, United Arab Emirates.

Purpose: The purpose of this study was to investigate the characteristic thoracic multidetector computed tomography (MDCT) findings of pathologically proven inflammatory myofibroblastic tumor (IMT) of the lung in children in the era of modern understanding based on refined pathologic diagnosis.

Materials And Methods: All pediatric patients (age 18 y and above) with a known pathologic diagnosis of IMT of the lung who underwent thoracic MDCT studies from May 2008 to December 2020 were included. Two pediatric radiologists independently evaluated thoracic MDCT studies for the presence of abnormalities in the lung (nodule, mass, cyst, ground-glass opacity, consolidation), pleura (pleural effusion, pneumothorax), and mediastinum and hilum (lymphadenopathy). Read More

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Prognostic Value and Therapeutic Implications of Pleural Carcinosis and Malignant Pleural Effusion in Advanced Epithelial Ovarian Cancer.

Anticancer Res 2021 Apr;41(4):2033-2038

Department of Gynecological Oncology and Tumor Surgery, European Competence Center for Ovarian Cancer, Charité Campus Virchow Clinic, Berlin, Germany;

Aim: To demonstrate the prognostic value of pleural carcinosis/effusion in a cohort of patients with advanced epithelial ovarian cancer (EOC) and the associated therapeutic implications.

Patients And Methods: Overall, data for 388 patients with EOC with confirmed malignant pleural effusion (MPE) or pleural carcinosis were retrospectively analyzed. Exclusion criteria were non-epithelial ovarian malignancies and presence of other comorbidities associated with pleural effusions. Read More

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