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Surgeon Factors Have a Larger Effect on Vascular Access Type and Outcomes than Patient Factors.

J Surg Res 2021 Apr 18;265:33-41. Epub 2021 Apr 18.

Division of Vascular Surgery, Department of Surgery, University of California, Los Angeles, California. Electronic address:

Background And Objectives: Though patient factors are frequently linked to hemodialysis vascular access selection and outcomes, variability by surgeon and surgeon specialty may play a role as well. The objective of this study is to examine the extent to which individual surgeons influence selection of vascular access type, removal of tunneled hemodialysis catheter (THC), and repeat vascular access.

Design, Setting, Participants, & Measurements: A national claims database was used to identify patients initiating hemodialysis via a THC between 2011 and 2017. Read More

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Predictors of Vision-Related Quality of Life After Endothelial Keratoplasty in the Descemet Endothelial Thickness Comparison Trials.

Cornea 2021 Apr;40(4):449-452

*F. I. Proctor Foundation, University of California, San Francisco, CA; †Casey Eye Institute, Oregon Health Sciences University, Portland, OR; ‡Byers Eye Institute, Stanford University, Palo Alto, CA; §Lions VisionGift, Portland, OR; ¶Department of Ophthalmology, University of California, San Francisco, CA; ‖Department of Epidemiology and Biostatistics, University of California, San Francisco, CA; and **Department of Research, Kaiser Permanente Northern California.

Purpose: To determine which baseline characteristics are associated with vision-related quality of life (QOL) after endothelial keratoplasty.

Methods: A patient- and outcome-masked randomized clinical trial. Consecutive patients presenting with isolated endothelial disease requiring endothelial keratoplasty at Oregon Health Sciences University and Stanford University. Read More

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Persistent Visual and Vestibular Impairments for Postural Control Following Concussion: A Cross-Sectional Study in University Students.

Sports Med 2021 Apr 21. Epub 2021 Apr 21.

Department of Kinesiology & Applied Physiology and Interdisciplinary Biomechanics and Movement Science Program, University of Delaware, Newark, DE, 19713, USA.

Objective: To examine how concussion may impair sensory processing for control of upright stance.

Methods: Participants were recruited from a single university into 3 groups: 13 participants (8 women, 21 ± 3 years) between 2 weeks and 6 months post-injury who initiated a return-to-play progression (under physician management) by the time of testing (recent concussion group), 12 participants (7 women, 21 ± 1 years) with a history of concussion (concussion history group, > 1 year post-injury), and 26 participants (8 women, 22 ± 3 years) with no concussion history (control group). We assessed sensory reweighting by simultaneously perturbing participants' visual, vestibular, and proprioceptive systems and computed center of mass gain relative to each modality. Read More

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The Meaning and Role of Spirituality for Older Adults: A Qualitative Study.

J Relig Health 2021 Apr 21. Epub 2021 Apr 21.

MSc Program Student in Psychiatric and Mental Health Nursing, Institute of Health Sciences, Kocaeli University, Izmit, Kocaeli, Turkey.

This study is designed to identify the meaning and effects perceived by a person concerning religion and spirituality as that person grows old. A total of nineteen adults aged 65-88, five of whom were male and fourteen of whom were female, participated in semistructured interviews. As per the results of the thematic analysis, four main themes emerged: the meaning of spirituality, spiritual practices, the effect of spirituality and the meaning of growing old for the person. Read More

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Associations of dietary and lifestyle oxidative balance scores with mortality risk among older women: the Iowa Women's Health Study.

Eur J Nutr 2021 Apr 21. Epub 2021 Apr 21.

Department of Epidemiology, Rollins School of Public Health, Emory University, Mailstop 1518-002-3BB, 1518 Clifton Road NE, Atlanta, GA, 30322, USA.

Purpose: Substantial basic science evidence suggests that oxidative stress may play a role in aging-related health outcomes, including cardiovascular diseases (CVD) and cancer, and oxidative stress markers were linked with all-cause and cause-specific mortality in epidemiologic studies. However, the associations of many individual dietary and lifestyle anti-/pro-oxidant exposures with mortality are inconsistent. Oxidative balance scores (OBS) that incorporated multiple dietary and lifestyle factors were previously developed and reported to reflect the collective oxidative effects of multiple exposures. Read More

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Development of cancer support services for patients and their close ones from the Cancer Society of Finland's perspective.

Int J Qual Stud Health Well-being 2021 Dec;16(1):1915737

Clinical Oncology, Department of Oncology, University of Turku, Turku, Finland.

: This study examined what support cancer patients and their close ones need and how this support should be organized when developing cancer care pathways. The study focused on the opinions of professionals of the Cancer Society of Finland (CSF), who play a central role in presenting the third sector's perspective on care pathways.: Six semi-structured group interviews were carried out with counselling nurses (n = 12) and managers (n = 9) of the CSF during summer 2017. Read More

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December 2021

Assessing Knowledge and Attitudes Regarding Pain Management Among Nurses Working in a Geriatric Hospital in Vietnam.

J Multidiscip Healthc 2021 12;14:799-807. Epub 2021 Apr 12.

Department of Geriatrics, Hanoi Medical University, Hanoi, 100000, Vietnam.

Background: Nurses play a pivotal role in pain management. Knowing more about nurses' knowledge and attitudes regarding pain is important as we develop multidisciplinary pain services. Therefore, this study aimed to assess knowledge and attitudes regarding pain management among nurses in a geriatric hospital and its associated factors. Read More

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Prognostic value of long noncoding RNA urothelial carcinoma-associated 1 in esophageal carcinoma: A protocol for meta-analysis, TCGA data and bioinformatics analysis.

Medicine (Baltimore) 2021 Apr;100(16):e25452

Department of Thoracic Surgery, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, 401120, China.

Background: Currently, an increasing number of long noncoding RNAs (LncRNAs) have been reported to be abnormally expressed in human carcinomas and play a vital role in tumourigenesis. Some studies have been carried out to investigate the influence of the expression of LncRNA human urothelial carcinoma associated 1 (UCA1) on prognosis and clinical significance in patients with esophageal cancer, but the results are contradictory and uncertain. A meta-analysis and was conducted with controversial data to accurately assess the issue. Read More

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Predicting disability progression and cognitive worsening in multiple sclerosis using patterns of grey matter volumes.

J Neurol Neurosurg Psychiatry 2021 Apr 20. Epub 2021 Apr 20.

NMR Research Unit, Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK.

Objective: In multiple sclerosis (MS), MRI measures at the whole brain or regional level are only modestly associated with disability, while network-based measures are emerging as promising prognostic markers. We sought to demonstrate whether data-driven patterns of covarying regional grey matter (GM) volumes predict future disability in secondary progressive MS (SPMS).

Methods: We used cross-sectional structural MRI, and baseline and longitudinal data of Expanded Disability Status Scale, Nine-Hole Peg Test (9HPT) and Symbol Digit Modalities Test (SDMT), from a clinical trial in 988 people with SPMS. Read More

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Mothers as perpetrators and bystanders of child sexual abuse.

Child Abuse Negl 2021 Apr 17;117:105068. Epub 2021 Apr 17.

Department of Child and Adolescent Psychiatry/Psychotherapy, University Hospital Ulm, Germany; Center for Child Protection in Medicine in Baden-Württemberg, Germany.

Background: In research and literature, little attention has been paid to the role of women, especially mothers, in child sexual abuse.

Objective: In order to estimate prevalences on mothers as perpetrators and bystanders, data was collected in a German nationwide representative survey.

Participants And Setting: A total of 2,531 participants (53. Read More

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Effect of NEUROG3 Polymorphism Rs144643855 on Regional Spontaneous Brain Activity in Major Depressive Disorder.

Behav Brain Res 2021 Apr 17:113310. Epub 2021 Apr 17.

Department of Psychosomatics and Psychiatry, ZhongDa Hospital, School of Medical, Southeast University, Nanjing, China; The Key Laboratory of Developmental Genes and Human Disease, Southeast University, Nanjing, China. Electronic address:

Purpose: Our previous study identified a significant association between a single nucleotide polymorphism (SNP) located in the neurogenin3 (NEUROG3) gene and post-stroke depression (PSD) in Chinese populations. The present work explores whether polymorphism rs144643855 affects regional brain activity and clinical phenotypes in major depressive disorder (MDD).

Method: A total of 182 participants were included: 116 MDD patients and 66 normal controls. Read More

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Performance After Concussion in National Hockey League Players.

J Athl Train 2021 Apr;56(4):404-407

School of Medicine, University of Maryland, Baltimore.

Context: Concussions in ice hockey players are an interesting area of study due to the fast-paced and high-impact nature of the sport. Recently, researchers have focused on player performance after return from concussion to evaluate subclinical deficits that were previously missed.

Objective: To examine National Hockey League (NHL) player performance from 2013 to 2019 and compare performance before a concussion with performance immediately after recovering to assess the current NHL return-to-play protocol. Read More

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Parents' attitudes towards school students' overuse of smartphones and its detrimental health impacts: A qualitative study.

JMIR Pediatr Parent 2021 Apr 20. Epub 2021 Apr 20.

Department of Immunology, Ministry of Health-Kuwait, Kuwait, KW.

Background: Parents' awareness of the risks of the overuse of smartphones (SPs) among their children and parents' attitudes towards this societal phenomenon are crucial factors to consider when investigating the causes and effects of, as well as interventions to control, this public health issue.

Objective: This study aimed to explore the awareness and attitudes of parents regarding SP overuse among their children and the detrimental impacts associated with it.

Methods: The qualitative method of semi-structured face-to-face interviews was used to collect data from fathers and mothers of children aged 6-18 years. Read More

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A Computational Evaluation of Two Models of Retrieval Processes in Sentence Processing in Aphasia.

Cogn Sci 2021 Apr;45(4):e12956

Department of Linguistics, University of Potsdam.

Can sentence comprehension impairments in aphasia be explained by difficulties arising from dependency completion processes in parsing? Two distinct models of dependency completion difficulty are investigated, the Lewis and Vasishth (2005) activation-based model and the direct-access model (DA; McElree, 2000). These models' predictive performance is compared using data from individuals with aphasia (IWAs) and control participants. The data are from a self-paced listening task involving subject and object relative clauses. Read More

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Association between cardiovascular diseases and depressive symptoms in adults. A pooled analysis of population-based surveys WOBASZ, NATPOL2011 and WOBASZ II.

Pol Arch Intern Med 2021 Apr 20. Epub 2021 Apr 20.

Introduction: Psychosocial risk factors play an important role in the origins of cardiovascular risk.

Objectives: To evaluate the prevalence of depressive symptoms (DS) in relation to some socio-demographic characteristics and selected cardiovascular diseases (CVD) and to assess the relationship between self-reported CVD and severity of DS.

Patients And Methods: Three cross-sectional population-based surveys: WOBASZ (2003-2005), NATPOL2011 (2011) and WOBASZ II (2013-2014) covered a total sample of 20,514 participants (9,614 men and 10,900 women), aged 20 - 74 years, who all completed a Beck Depression Inventory. Read More

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The Role of the Patients' Companion in the Transitional Care from the Open Heart Surgery ICU to the Cardiac Surgery Ward: A Qualitative Content Analysis.

Int J Community Based Nurs Midwifery 2021 Apr;9(2):117-126

Department of Medical-Surgical Nursing, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran.

Background: The patients' companions can help improve transitional care as an important missing link, but their role is not clear. The aim of this study was to explore the role of the patients' companion in the transitional care from the open heart surgery intensive care unit (OH-ICU) to the cardiac surgery ward.

Methods: This was a qualitative descriptive study using conventional content analysis that was conducted from September 2019 to February 2020 in Tehran, Iran. Read More

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Critical incidents in anorexia nervosa: perspectives of those with a lived experience.

J Eat Disord 2021 Apr 19;9(1):53. Epub 2021 Apr 19.

School of Education, University of Bristol, Bristol, UK.

Background: Although social-emotional difficulties are believed play a key role in anorexia nervosa (AN), there is uncertainty regarding what these difficulties might look like. Previous research has largely focused on a "disease model" of social-emotional processing in AN with little attention paid to positive emotions and experiences. Therefore, the aim of the present study was to obtain a fuller picture of critical life events as identified by those with lived AN experience. Read More

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Regulation of circulating CTRP-2/CTRP-9 and GDF-8/GDF-15 by intralipids and insulin in healthy control and polycystic ovary syndrome women following chronic exercise training.

Lipids Health Dis 2021 Apr 19;20(1):34. Epub 2021 Apr 19.

Qatar Metabolic Institute, Department of Medicine and Academic Health System, Hamad Medical Corporation, Doha, Qatar.

Background: Polycystic ovary syndrome (PCOS) is associated with obesity, diabetes, and insulin resistance. The circulating C1Q/TNF-related proteins (CTRP-2, CTRP-9) and growth differentiation factors (GDF-8, GDF-15) contribute to glucose and lipid homeostasis. The effects of intralipids and insulin infusion on CTRP-2, CTRP-9, GDF-8 and GDF-15 in PCOS and control subjects before and after chronic exercise training were examined. Read More

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The Impact of Eye-gaze Controlled Computer on Communication and Functional Independence in Children and Young People with Complex Needs - A Multicenter Intervention Study.

Dev Neurorehabil 2021 Apr 19:1-14. Epub 2021 Apr 19.

Department of Special Education, Stockholm University, Stockholm, Sweden.

Introduction: Children and young people with complex needs (severe motor impairments and without speech) have few opportunities to use alternative devices for communication. Eye-gaze controlled computers (EGCCs) might provide individuals with complex needs increased opportunities for communication and participation in society.

Objective: To investigate the impact of EGCCs on communication, functional independence and participation in activities in children and young people with complex needs. Read More

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Rights-Based Training Enhancing Engagement of Health Providers With Communities, Cape Metropole, South Africa.

Front Sociol 2019 30;4:35. Epub 2019 Apr 30.

Health and Human Rights Programme, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.

Community participation, the central principle of the primary health care approach, is widely accepted in the governance of health systems. Health Committees (HCs) are community-based structures that can enable communities to participate in the governance of primary health care. Previous research done in the Cape Town Metropole, South Africa, reports that HCs' potential can, however, be limited by a lack of local health providers' (HPs) understanding of HC roles and functions as well as lack of engagement with HCs. Read More

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Effect of Inflammatory Cytokines/Chemokines on Pulmonary Tuberculosis Culture Conversion and Disease Severity in HIV-Infected and -Uninfected Individuals From South Africa.

Front Immunol 2021 1;12:641065. Epub 2021 Apr 1.

Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.

Novel tuberculosis (TB) prevention and control strategies are urgently required. Utilising specimens from the Improving Retreatment Success (NCT02114684) trial we assessed the associations between inflammatory markers, measured during active TB, with treatment response and disease severity in HIV-infected and uninfected individuals. Multiplex immunoassays and ELISA were used to measure plasma expression of 24 cytokines/chemokines. Read More

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Pregnancy or Psychological Outcomes of Psychotherapy Interventions for Infertility: A Meta-Analysis.

Front Psychol 2021 31;12:643395. Epub 2021 Mar 31.

Department of Neurology, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.

The pregnancy and psychological status of infertile couples has always been a concern, but there is no clear evidence for the efficacy of psychotherapy for infertile couples. This study aimed to summarize the current evidence of the effects of psychotherapy on psychological and pregnancy outcomes for infertile couples. We searched Ovid MEDLINE, Ovid EMbase, The Cochrane Library, and Web of Science (ISI) for articles published from 1946 to June 26, 2020. Read More

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Physical Activity Levels of Adult Virtual Football Players.

Front Psychol 2021 26;12:596434. Epub 2021 Mar 26.

Portugal Football School, Portuguese Football Federation, FPF, Cruz Quebrada, Portugal.

Esports, including virtual football, are a worldwide phenomenon. Yet, little is known about the physical activity levels of individuals engaged in virtual football game play. Therefore, we aimed to perform a preliminary evaluation of the levels of physical activity, sedentarism, and habits of physical training of adults engaged with virtual football in Portugal. Read More

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Study Protocol: The Heart and Brain Study.

Front Physiol 2021 31;12:643725. Epub 2021 Mar 31.

Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, United Kingdom.

Background: It is well-established that what is good for the heart is good for the brain. Vascular factors such as hypertension, diabetes, and high cholesterol, and genetic factors such as the apolipoprotein E4 allele increase the risk of developing both cardiovascular disease and dementia. However, the mechanisms underlying the heart-brain association remain unclear. Read More

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Using a machine learning approach to explore predictors of healthcare visits as missed opportunities for HIV diagnosis.

AIDS 2021 May;35(Suppl 1):S7-S18

South Carolina SmartState Center for Healthcare Quality.

Objectives: A significant number of individuals with a new HIV diagnosis are still late presenters despite numerous healthcare encounters prior to HIV diagnosis. We employed a machine learning approach to identify the predictors for the missed opportunities for earlier HIV diagnosis.

Methods: The cohort comprised of individuals who were diagnosed with HIV in South Carolina from January 2008 to December 2016. Read More

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Incivility among nursing faculty: A multi-country study.

J Prof Nurs 2021 Mar-Apr;37(2):379-386. Epub 2020 Apr 6.

Majmaah University, Saudi Arabia. Electronic address:

Background: In nursing programs, incivility can be a main issue affecting future registered nurses, and this may threaten patient safety. Nursing faculty play an important role in this scenario to reduce incivility.

Purpose: The aim of this study was to assess incivility among nursing faculty in different countries. Read More

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Creating a community of researchers: Fostering global collaboration for doctoral prepared nurses and nursing students.

J Prof Nurs 2021 Mar-Apr;37(2):354-358. Epub 2020 Apr 18.

Johns Hopkins School of Nursing, 525 North Wolfe Street, Baltimore, MD 20125, United States of America.

Background: Few publications have explored the role that professional organizations play in facilitating global partnerships; particularly regarding research and educational collaboration between doctoral prepared nurses and students residing in low- and middle-income countries with those from high-income countries.

Objective: To describe a pilot Spotlight Project which was developed to foster communication and collaboration among global doctoral prepared nurses and nursing students within an international nursing organization.

Methods: Twenty-seven members were identified and sent requests to complete the spotlight form created for this project. Read More

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Altered relationship between subjective perception and central representation of touch hedonics in adolescents with autism-spectrum disorder.

Transl Psychiatry 2021 Apr 17;11(1):224. Epub 2021 Apr 17.

Center for Social and Affective Neuroscience, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.

An impairment of social communication is a core symptom of autism-spectrum disorder (ASD). Affective touch is an important means of social interaction, and C-Tactile (CT) afferents are thought to play a key role in the peripheral detection and encoding of these stimuli. Exploring the neural and behavioral mechanisms for processing CT-optimal touch (~3 cm/s) may therefore provide useful insights into the pathophysiology of ASD. Read More

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