PLoS Genet 2019 10 18;15(10):e1008448. Epub 2019 Oct 18.
Department of Biology, Indiana University, Bloomington, Indiana, United States of America.
Bacterial type IV pili are critical for diverse biological processes including horizontal gene transfer, surface sensing, biofilm formation, adherence, motility, and virulence. These dynamic appendages extend and retract from the cell surface. In many type IVa pilus systems, extension occurs through the action of an extension ATPase, often called PilB, while optimal retraction requires the action of a retraction ATPase, PilT. Read More