1,220 results match your criteria pig permanent

Comparison of Uterine Necrosis After Uterine Artery Embolization with Soluble Gelatin Sponge Particles or Tris-acryl Gelatin Microspheres in Swine.

Cardiovasc Intervent Radiol 2021 Jul 6. Epub 2021 Jul 6.

Department of Radiology, Wakayama Medical University, 811-1 Kimiidera, Wakayama City, 641-8510, Japan.

Purpose: To compare the recanalization of the uterine arteries and uterine necrosis after uterine artery embolization (UAE) using either soluble gelatin sponge particles (SGS), which dissolve in saline, or tris-acryl gelatin microspheres (MS), which are permanent embolic materials, in swine.

Methods: Fourteen uteri in seven swine were divided into two groups for embolization with either 500-1000 µm SGS (SGS group) or 500-700 µm MS (MS group) (seven uteri per group). The uterine arteries were embolized using SGS or MS, and angiography was performed to evaluate recanalization of the uterine arteries immediately, 1, 2, 3, 4, 5, and 6 h, and 3 days after embolization. Read More

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Applying basic principles of surgery may pave the way for more effective endoscopic bariatric techniques.

Endosc Int Open 2021 Jul 17;9(7):E1049-E1054. Epub 2021 Jun 17.

Department of Digestive Endoscopy, Hospital Sírio-Libanês, São Paulo, Brazil.

 In the last decade, gastroenterologists have been attempting to use endoscopy to reproduce the great success of traditional surgical suture techniques. Despite recent advances, we still lack a reliable method that results in a permanent suture with minimal incidence of suture failure. This was an experimental study in pigs with an innovative technique that applied basic surgical concepts to endoscopy to evaluate the effectiveness of a novel suture technique. Read More

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A multiplex assay for the detection of antibodies to relevant swine pathogens in serum.

Transbound Emerg Dis 2021 Jul 2. Epub 2021 Jul 2.

Research Department, Eurofins-Ingenasa, Madrid, Spain.

Livestock industry supports the livelihood of around 1.3 billion people in the world, with swine industry contributing with 30% of total livestock production worldwide. To maintain and guarantee this production, a pivotal point according to the OIE is addressing potential biohazards. Read More

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Effects of temperature on proliferation of myoblasts from donor piglets with different thermoregulatory maturities.

BMC Mol Cell Biol 2021 Jun 26;22(1):36. Epub 2021 Jun 26.

Institute of Muscle Biology and Growth, Leibniz Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196, Dummerstorf, Germany.

Background: Climate change and the associated risk for the occurrence of extreme temperature events or permanent changes in ambient temperature are important in the husbandry of farm animals. The aim of our study was to investigate the effects of permanent cultivation temperatures below (35 °C) and above (39 °C, 41 °C) the standard cultivation temperature (37 °C) on porcine muscle development. Therefore, we used our porcine primary muscle cell culture derived from satellite cells as an in vitro model. Read More

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Neuropathological and Motor Impairments after Incomplete Cervical Spinal Cord Injury in Pigs.

J Neurotrauma 2021 Jul 15. Epub 2021 Jul 15.

Neural Repair Laboratory, Hospital Nacional de Parapléjicos, Toledo, Spain.

Humans, primates, and rodents with cervical spinal cord injury (SCI) show permanent sensorimotor dysfunction of the upper/forelimb as consequence of axonal damage and local neuronal death. This work aimed at characterizing a model of cervical SCI in domestic pigs in which hemisection with excision of 1 cm of spinal cord was performed to reproduce the loss of neural tissue observed in human neuropathology. Posture and motor control were assessed over 3 months by scales and kinematics of treadmill locomotion. Read More

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One Health initiative in the Bolivian Altiplano human fascioliasis hyperendemic area: Lymnaeid biology, population dynamics, microecology and climatic factor influences.

Rev Bras Parasitol Vet 2021 28;30(2):e025620. Epub 2021 May 28.

Departamento de Parasitologia, Facultad de Farmacia, Universidad de Valencia, Valencia, Spain.

Fascioliasis is a freshwater snail-borne zoonotic disease. The Northern Bolivian Altiplano is a very high altitude endemic area where the highest human prevalences and intensities have been reported. Preventive chemotherapy by treatment campaigns is yearly applied. Read More

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Ecological Adaptations of Gut Microbiota Members and Their Consequences for Use as a New Generation of Probiotics.

Int J Mol Sci 2021 May 22;22(11). Epub 2021 May 22.

Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic.

In this review, we link ecological adaptations of different gut microbiota members with their potential for use as a new generation of probiotics. Gut microbiota members differ in their adaptations to survival in aerobic environments. Interestingly, there is an inverse relationship between aerobic survival and abundance or potential for prolonged colonization of the intestinal tract. Read More

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Domestic pig prioritized in one health action against fascioliasis in human endemic areas: Experimental assessment of transmission capacity and epidemiological evaluation of reservoir role.

One Health 2021 Dec 16;13:100249. Epub 2021 Apr 16.

Departamento de Parasitología, Facultad de Farmacia, Universidad de Valencia, Av. Vicent Andrés Estellés s/n, 46100 Burjassot, Valencia, Spain.

The Northern Bolivian Altiplano is the human fascioliasis hyperendemic area where the highest prevalences and intensities in humans have been reported. Preventive chemotherapy was implemented in the last ten years. Surveillance showed high human infection and re-infection rates in between the annual triclabendazole monodose treatments. Read More

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December 2021

Exploring the influence of impact severity and posture on vertebral joint mechanics in an in-vitro porcine model.

J Biomech 2021 06 25;122:110479. Epub 2021 Apr 25.

Department of Kinesiology, University of Waterloo, Waterloo, ON, Canada. Electronic address:

To date, no in vitro studies have been conducted to explore lumbar soft tissue injury potential and altered mechanical properties from exposure to impact forces. After a motor vehicle collision (MVC), the cause of reported acute onset low back pain is difficult to associate with potential soft tissue strain injury sites including the facet joint and innervated facet joint capsule ligament (FJC). Thus, the purpose of this investigation was to quantify intervertebral anterior-posterior (AP) translation and facet joint capsule strain under varying postures and impact severities. Read More

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[Research progress in studies on tooth development based on diphyodont mammals].

Zhonghua Kou Qiang Yi Xue Za Zhi 2021 May 9;56(5):497-501. Epub 2021 May 9.

Department of Prosthodontics, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.

For decades, the molecular and cellular mechanisms that govern tooth development have been extensively investigated. However, most of the studies are based on mice, whose teeth are quite different from human teeth in morphological and developmental aspects. Mice are not the ideal model for understanding the development of permanent teeth as they have only one set of dentition. Read More

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Determining insulin sensitivity from glucose tolerance tests in Iberian and landrace pigs.

PeerJ 2021 10;9:e11014. Epub 2021 Mar 10.

Department of Physiology and Biochemistry of Animal Nutrition, Estación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas, Granada, Spain.

As insulin sensitivity may help to explain divergences in growth and body composition between native and modern breeds, metabolic responses to glucose infusion were measured using an intra-arterial glucose tolerance test (IAGTT). Iberian ( = 4) and Landrace ( = 5) barrows (47.0 ± 1. Read More

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Improvement of tangential microfiltration of gelatin solution using a permanent magnetic field.

J Food Sci Technol 2021 Mar 9;58(3):1093-1100. Epub 2020 Jul 9.

Laboratory of Membrane Processes, LABSEM, Department of Chemical and Food Engineering, Federal University of Santa Catarina, Florianópolis, SC 88040-900 Brazil.

Membrane technology is an interesting alternative to conventional gelatin clarification methods, resulting in the elimination of refining chemical agents. In this work, the application of a permanent magnetic field as a pre-treatment of the gelatin solutions was proposed as a strategy to improve the microfiltration (MF) performance. Filtration tests were performed using a 1. Read More

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Vascular Response of a Polymer-Free Paclitaxel-Coated Stent (Zilver PTX) versus a Polymer-Coated Paclitaxel-Eluting Stent (Eluvia) in Healthy Swine Femoropopliteal Arteries.

J Vasc Interv Radiol 2021 06 4;32(6):792-801.e5. Epub 2021 Mar 4.

CVPath Institute, Gaithersburg, Maryland; Department of Medicine, School of Medicine, University of Maryland, Baltimore, Maryland. Electronic address:

Purpose: To compare the long-term vascular healing responses of healthy swine iliofemoral arteries treated with a polymer-free paclitaxel-eluting stent (Z-PES, Zilver PTX) or a fluoropolymer-based paclitaxel-eluting stent (FP-PES, Eluvia).

Materials And Methods: Bilateral iliofemoral arteries in 20 swine were treated with a Z-PES (n = 16) or a FP-PES (n = 24) and were examined histologically at 1, 3, 6, and 12 months.

Results: Morphometric analysis revealed larger external and internal elastic lamina, stent expansion, and lumen area in the FP-PES than in the Z-PES at all timepoints. Read More

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Osteogenic potential of dental and oral derived stem cells in bone tissue engineering among animal models: An update.

Tissue Cell 2021 Feb 24;71:101515. Epub 2021 Feb 24.

Laboratory of Cancer Biology and Molecular Immunology, Faculty of Sciences-I, Lebanese University, Hadath- Beirut, Lebanon. Electronic address:

Small bone defects can heal spontaneously through the bone modeling process due to their physiological environmental conditions. The bone modeling cycle preserves the reliability of the skeleton through the well-adjusted activities of its fundamental cell. Stem cells are a source of pluripotent cells with a capacity to differentiate into any tissue in the existence of a suitable medium. Read More

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February 2021

An ultralow dose paclitaxel coated drug balloon with an outer protective sheath for peripheral arterial disease treatment.

J Mater Chem B 2021 03;9(10):2428-2435

National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, P. R. China.

Use of a drug-eluting coated balloon (DCB) represents a promising therapeutic method for peripheral arterial disease (PAD) due to its advantages such as no implant permanently retained in the patient and no inflammatory reaction and endothelialization barrier caused by a permanent stent. However, there is still a huge challenge of controlling the release of drugs from the DCB into vessel tissue. The uncontrolled release of drugs and high drug loading amounts could potentially lead to distal embolization and mortality events. Read More

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[Ex-vivo experimental study of ultrasound-guided radiofrequency ablation for the treatment of hepatocellular carcinoma].

Q Wang C Sun L J Niu

Zhonghua Zhong Liu Za Zhi 2021 Feb;43(2):188-193

Department of Ultrasound, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

To explore the effective mode of ultrasound-guided radiofrequency ablation for the treatment of hepatocellular carcinoma (HCC). The morphological changes of human liver cancer cells HepG2 and human permanent liver cells LO2 after high temperature treatment were observed. The cell counting kit 8 (CCK-8) array was used to detect cell proliferation ability. Read More

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February 2021

Assessment of lying down behaviour in temporarily crated lactating sows.

Animal 2021 Feb 25;15(2):100130. Epub 2020 Dec 25.

Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, Kamýcká 129, 160 21 Praha-Suchdol, Czech Republic.

Temporary crating may be a more acceptable housing system for lactating sows than permanent crating from an animal welfare point of view. It remains unclear whether opening the crate leads to changes in sow lying down behaviour and piglet activity that may pose an increased risk of injury to piglets. This study aimed to assess whether the lying down behaviour of lactating sows housed in temporary crating changed shortly after removal of confinement, whether it was influenced by piglets' behaviour and age and whether sows preferentially used some support during lying down after crate opening. Read More

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February 2021

Chronic Hyperglycemia Drives Functional Impairment of Lymphocytes in Diabetic Transgenic Pigs.

Front Immunol 2020 22;11:607473. Epub 2021 Jan 22.

Chair of Physiology, Department of Veterinary Sciences, LMU Munich, Munich, Germany.

People with diabetes mellitus have an increased risk for infections, however, there is still a critical gap in precise knowledge about altered immune mechanisms in this disease. Since diabetic transgenic pigs exhibit elevated blood glucose and a stable diabetic phenotype soon after birth, they provide a favorable model to explore functional alterations of immune cells in an early stage of diabetes mellitus . Hence, we investigated peripheral blood mononuclear cells (PBMC) of these diabetic pigs compared to non-diabetic wild-type littermates. Read More

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Magnetic Resonance Imaging and Gait Analysis Indicate Similar Outcomes Between Yucatan and Landrace Porcine Ischemic Stroke Models.

Front Neurol 2020 21;11:594954. Epub 2021 Jan 21.

Regenerative Bioscience Center, University of Georgia, Athens, GA, United States.

The Stroke Therapy Academic Industry Roundtable (STAIR) has recommended that novel therapeutics be tested in a large animal model with similar anatomy and physiology to humans. The pig is an attractive model due to similarities in brain size, organization, and composition relative to humans. However, multiple pig breeds have been used to study ischemic stroke with potentially differing cerebral anatomy, architecture and, consequently, ischemic stroke pathologies. Read More

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January 2021

Semi-Automated Cell and Tissue Analyses Reveal Regionally Specific Morphological Alterations of Immune and Neural Cells in a Porcine Middle Cerebral Artery Occlusion Model of Stroke.

Front Cell Neurosci 2020 22;14:600441. Epub 2021 Jan 22.

Regenerative Bioscience Center, University of Georgia, Athens, GA, United States.

Histopathological analysis of cellular changes in the stroked brain provides critical information pertaining to inflammation, cell death, glial scarring, and other dynamic injury and recovery responses. However, commonly used manual approaches are hindered by limitations in speed, accuracy, bias, and the breadth of morphological information that can be obtained. Here, a semi-automated high-content imaging (HCI) and CellProfiler histological analysis method was developed and used in a Yucatan miniature pig permanent middle cerebral artery occlusion (pMCAO) model of ischemic stroke to overcome these limitations. Read More

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January 2021

Experimental near-infrared spectroscopy-guided minimally invasive segmental artery occlusion.

Eur J Cardiothorac Surg 2021 07;60(1):48-55

University Department for Cardiac Surgery, Leipzig Heart Center, Saxony, Germany.

Objectives: Minimally invasive staged segmental artery (SA) coil- and plug embolization is a new method for paraplegia prevention associated with extensive aortic procedures. Near-infrared spectroscopy of the paraspinal collateral network (cnNIRS) has emerged as a non-invasive method for spinal cord monitoring. The aim of this study was to evaluate cnNIRS to guide minimally invasive SA occlusion. Read More

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In Vivo Intravascular Pacing Using a Wireless Microscale Stimulator.

Ann Biomed Eng 2021 Feb 3. Epub 2021 Feb 3.

Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, 90095, USA.

Millions of patients worldwide are implanted with permanent pacemakers for the treatment of cardiac arrhythmias and conduction disorders. The increased use of these devices has established a growing clinical need to mitigate associated complications. Pacemaker leads, in particular, present the primary risks in most implants. Read More

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February 2021

Genetic relationship between litter size traits at birth and body measurement and production traits in purebred Duroc pigs.

Anim Sci J 2020 Jan;91(1):e13497

Graduate School of Agricultural Science, Tohoku University, Sendai, Japan.

Heritabilities of litter size traits at birth (total number born (TNB), number born alive (NBA), and number still born (NSB)) and their genetic correlations with body measurement (body height, body length, front width (FW), chest width (CW), hind width, chest depth, chest girth, front cannon circumference, and rear cannon circumference) and production traits (ages at the start and end of performance testing (D30 and D105), average daily gain (ADG), backfat thickness, and loin muscle area) in purebred Duroc pigs were estimated. Records of performance testing for 2,835 animals and farrowing records of 1,168 litters from 437 dams were used. Genetic parameters were estimated using single-trait and two-trait animal models. Read More

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January 2020

Secreted frizzled protein 3 is a novel cardioprotective mechanism unique to the clinically relevant fourth window of ischemic preconditioning.

Am J Physiol Heart Circ Physiol 2021 02 18;320(2):H798-H804. Epub 2020 Dec 18.

Department of Cell Biology and Molecular Medicine, Rutgers University, New Jersey Medical School, Newark, New Jersey.

Most studies on ischemic preconditioning (IPC) use one or two ischemic stimuli before examining cardioprotection. To better simulate the clinical situation, we examined, in pigs, the effects of six episodes of 10 min coronary artery occlusion (CAO) 12 h apart, followed by 60 min CAO. We named this model the fourth window of IPC. Read More

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February 2021

Novel 3D-printed hollow microneedles facilitate safe, reliable, and informative sampling of perilymph from guinea pigs.

Hear Res 2021 Feb 2;400:108141. Epub 2020 Dec 2.

Department of Otolaryngology - Head and Neck Surgery, Columbia University Vagelos College of Physicians and Surgeons, 180 Fort Washington Avenue, Harkness Pavilion, 8th Floor, New York, NY 10032, United States; Department of Mechanical Engineering, Columbia University, New York, NY, United States. Electronic address:

Background: Inner ear diagnostics is limited by the inability to atraumatically obtain samples of inner ear fluid. The round window membrane (RWM) is an attractive portal for accessing perilymph samples as it has been shown to heal within one week after the introduction of microperforations. A 1 µL volume of perilymph is adequate for proteome analysis, yet the total volume of perilymph within the scala tympani of the guinea pig is limited to less than 5 µL. Read More

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February 2021

African swine fever: A permanent threat to Indian pigs.

Vet World 2020 Oct 29;13(10):2275-2285. Epub 2020 Oct 29.

Indian Council of Agricultural Research-National Institute of Veterinary Epidemiology and Disease Informatics, Bengaluru, Karnataka, India.

India has 9 million pigs, of which 45% are in the North eastern (NE) states of India. Viral diseases affecting pigs are a major concern of mortality causing huge loss to the pig farmers. One such disease is African swine fever (ASF) that has already knocked the porous borders of NE states of India. Read More

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October 2020

Evaluation of a cross-linked versus non-cross-linked collagen matrix in full-thickness skin defects.

Burns 2021 02 2;47(1):150-156. Epub 2020 Dec 2.

Department of Plastic, Reconstructive, Hand and Burn Surgery, BG-Trauma Center Tuebingen, Eberhard Karls University Tuebingen, Germany. Electronic address:

Autologous skin transplantation is the gold standard for treatment of full-thickness skin defects such as deep burn injuries, but has the disadvantages of limited donor sites and donor site morbidities. Alternative skin replacement products, such as xenografts and allografts, are not a permanent solution. Numerous manufactured skin substitutes already show promising approaches, but have limited efficacy. Read More

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February 2021

[Clinical, ethologic, endokrinologic, and metabolic aspects of the peripartal period in pigs].

Tierarztl Prax Ausg G Grosstiere Nutztiere 2020 Dec 4;48(6):414-421. Epub 2020 Dec 4.

Klinik für Geburtshilfe, Gynäkologie und Andrologie der Groß- und Kleintiere, Justus-Liebig-Universität Gießen.

The aim of this review article is to provide an overview of the literature relevant to the peripartal period in swine. As in all other mammals, the farrowing process in pigs is divided into 3 phases (I-III; opening, expulsion, and postnatal stage), during which various essential endocrine and metabolic mechanisms initiate or maintain parturition. These include the hormones progesterone, cortisol, prostaglandin F, oxytocin, estradiol, relaxin as well as electrolytes, enzymes, and metabolites such as calcium, magnesium, inorganic phosphate, glucose, creatine kinase, lactate, non-esterified free fatty acids, and β-hydroxybutyrate. Read More

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December 2020

Comparative scanning electron microscope analysis of the enamel of permanent human, bovine and porcine teeth.

J Vet Sci 2020 Nov;21(6):e83

Department of Conservative Dentistry, Medical University of Lodz, 92-217 Łódź, Poland.

Background: Bovine and porcine teeth are often used in experiments as substitutes of human teeth.

Objectives: The aim of the present study was to perform a comparative analysis of enamel morphology of permanent human, bovine and porcine teeth under the scanning electron microscope.

Methods: As many as 10 human, 10 bovine, and 10 porcine teeth were studied. Read More

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November 2020

Thromboresistance and endothelial healing in polymer-coated versus polymer-free drug-eluting stents: Implications for short-term dual anti-platelet therapy.

Int J Cardiol 2021 03 23;327:52-57. Epub 2020 Nov 23.

CVPath Institute, Gaithersburg, MD, United States of America; University of Maryland, Baltimore, MD, United States of America. Electronic address:

Background: Short-term dual antiplatelet therapy (DAPT) is a suitable strategy after stent implantation especially in patients at high risk for bleeding. The thromboresistant characteristics and the healing profile permanent polymer stents such as the Resolute Onyx- drug-eluting stent (DES) has never been tested against the current approved stents for short-term DAPT, the polymer free (PF) biolimus-eluting stent (PF-BES) and bare metal stents (BMS) in dedicated preclinical models.

Methods: An ex-vivo porcine arteriovenous shunt and in-vivo flow loop model were used to evaluate thromboresistance. Read More

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