594,454 results match your criteria physical activity


The effects of stroboscopic balance training on cortical activities in athletes with chronic ankle instability.

Phys Ther Sport 2021 Apr 14;50:50-58. Epub 2021 Apr 14.

Faculty of Physical Therapy and Rehabilitation Hacettepe University, Ankara, 06100, Turkey. Electronic address:

Objectives: To investigate the effect of a 6-week stroboscopic balance training program on cortical activities in athletes with chronic ankle instability.

Design: Randomized controlled trial.

Setting: Single-center. Read More

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A longitudinal investigation of landing biomechanics following anterior cruciate ligament reconstruction.

Phys Ther Sport 2021 Mar 31;50:36-41. Epub 2021 Mar 31.

School of Allied Health, Human Services and Sport, La Trobe University, Melbourne, Australia; OrthoSport Victoria Research Unit, Melbourne, Australia.

Objective: Abnormal movement patterns have been shown during landing in patients who have undergone anterior cruciate ligament (ACL) reconstruction surgery. The purpose of this study was to investigate landing biomechanics over time in this patient group to determine whether asymmetry between limbs reduced with time and after a return to physical activity.

Design: Prospective longitudinal study. Read More

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Decreased serum testosterone levels associated with 17β-hydroxysteroid dehydrogenase activity in 7-year-old children from a dioxin-exposed area of Vietnam.

Sci Total Environ 2021 Mar 30;783:146701. Epub 2021 Mar 30.

Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Japan.

Since 2008, we have conducted epidemiological cohort studies on the relationship between dioxin exposure and disruption with children in the area sprayed with defoliants during the Vietnam War. In a long-term survey of children through the age of five, we observed androgen disruption due to decreased dehydroepiandrosterone (DHEA) and testosterone levels. In this study of 7-year-old, we separately elucidated androgen disruption for boys and girls, and discussed with respect to hormone disruption with sex differences on the steroid hormone biosynthesis process. Read More

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Physical activity status and quality of life in patients with epilepsy - Survey from level four epilepsy monitoring units.

Epilepsy Res 2021 Apr 9;173:106639. Epub 2021 Apr 9.

Department of Neurology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, TX, 75390, USA. Electronic address:

Purpose: People with epilepsy (PWE) tend to have sedentary lifestyles which may predispose them to a lower perceived quality of life (QOL). Moreover, the relationship between physical activity (PA) and QOL in populations of PWE with high disease burden has been under-studied. The goal of this study was to evaluate PA level and its impact on health-related QOL in PWE who were admitted to Level-4 epilepsy monitoring units (EMU). Read More

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[Long-term effect analysis of a cognitive stimulation program in mild cognitive impairment elderly in Primary Care: A randomized controlled trial].

Aten Primaria 2021 Apr 14;53(7):102053. Epub 2021 Apr 14.

Residencia Reyes de Aragón/Orpea, Zaragoza, España. Electronic address:

Objective: To provide evidence about the efficacy of a community health intervention through a cognitive stimulation program at long term in older people with mild cognitive impairment.

Design: Randomized controlled trial (CONSORT group norms).

Location: San José Norte-Centro Primary Care Center and La Caridad Foundation (Zaragoza, Spain). Read More

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Sleep and physical activity in university students: A systematic review and meta-analysis.

Sleep Med Rev 2021 Mar 20;58:101482. Epub 2021 Mar 20.

Appleton Institute, Central Queensland University, Adelaide, Australia.

University students have low levels of physical activity and report disturbances to sleep, which are independently associated with poor health outcomes. Some research suggests that there is a bi-directional relationship between sleep and physical activity in adults. However, the relationship between sleep and physical activity in university students has not yet been evaluated. Read More

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Estimated Glomerular Filtration Rate (eGFR) based on cystatin C was associated with increased risk of hip and proximal humerus fractures in women and decreased risk of hip fracture in men, whereas eGFR based on creatinine was not associated with fracture risk in both sexes: The Tromsø Study.

Bone 2021 Apr 14:115960. Epub 2021 Apr 14.

Women's Health and Perinatalogy Research Group, Department of Clinical Medicine, UiT The Arctic University of Norway, Tromsø, Norway; Department of Gynecology and Obstetrics, University Hospital of North Norway, Tromsø, Norway; Norwegian Research Centre for Women's Health, Oslo University Hospital, Oslo, Norway. Electronic address:

Purpose: Patients with end-stage kidney disease have an increased fracture risk. Whether mild to moderate reductions in kidney function is associated with increased fracture risk is uncertain. Results from previous studies may be confounded by muscle mass because of the use of creatinine-based estimates of the glomerular filtration rate (eGFRcre). Read More

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Time-dependent effects of inspiratory muscle training and detraining on cardiac autonomic control in older women.

Exp Gerontol 2021 Apr 14:111357. Epub 2021 Apr 14.

Department of Physiology and Pharmacology, Fluminense Federal University, Niterói, Brazil. Electronic address:

Inspiratory muscle training improved maximal inspiratory pressure (MIP) and vagal-mediated heart rate variability (HRV) in older women. However, it is unknown what occurs if the training is discontinued (detraining protocol). The aim of this study was to investigate the IMT and detraining effects on resting HRV in older women. Read More

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Determinants of cardiac structure in frail and sarcopenic elderly adults.

Exp Gerontol 2021 Apr 14:111351. Epub 2021 Apr 14.

Department of Medicine and Surgery, University Medical School of Parma, Parma, Italy; University-Hospital of Parma, Parma, Italy; Geriatric Clinic Unit, University-Hospital of Parma, Parma, Italy.

Background: Cardiac structure and function change with age. The higher prevalence of left ventricular hypertrophy (LVH) with concentric remodeling is indicative of a typical geometric pattern of aging associated with a higher cardiovascular (CV) risk and diseases. The recent associations found between low left ventricular and skeletal mass in older patients with frailty and sarcopenia have raised great interest in investigating cardiac characteristics and determinants of left ventricular mass (LVM) in this population. Read More

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Effects of 5-aminolevulinic acid with iron supplementation on respiratory responses to graded cycling and interval walking training achievement in older women over 75 yrs.

Exp Gerontol 2021 Apr 14:111356. Epub 2021 Apr 14.

Departments of Sports Medical Sciences, Shinshu University Graduate School of Medicine, Matsumoto 390-8621, Japan; Departments of e-Health Sciences, Shinshu University Graduate School of Medicine, Matsumoto 390-8621, Japan.

Background: Exercise training above a given intensity is necessary to prevent age-associated physical disability and diseases; however, the physical and psychological barriers posed by deteriorated physical fitness due to aging may hinder older people from performing daily exercise training. Because 5-aminolevulinic acid (ALA), a precursor of heme, reportedly improves mitochondrial function, we examined whether ALA, combined with sodium ferrous citrate (SFC) for enhancement, improved aerobic capacity and voluntary exercise training achievement in older women aged over 75 yrs.

Methods: The study was conducted using a placebo-controlled, double-blind crossover design. Read More

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Mitochondria-associated membrane-modulated Ca transfer: A potential treatment target in cardiac ischemia reperfusion injury and heart failure.

Life Sci 2021 Apr 14:119511. Epub 2021 Apr 14.

Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Key Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang Province, China. Electronic address:

Effective Ca dependent mitochondrial energy supply is imperative for proper cardiac contractile activity, while disruption of Ca homeostasis participates in the pathogenesis of multiple human diseases. This phenomenon is particularly prominent in cardiac ischemia and reperfusion (I/R) and heart failure, both of which require strict clinical intervention. The interface between endoplasmic reticula (ER) and mitochondria, designated the mitochondria-associated membrane (MAM), is now regarded as a crucial mediator of Ca transportation. Read More

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Post-exercise recovery for the endurance athlete with type 1 diabetes: a consensus statement.

Lancet Diabetes Endocrinol 2021 May;9(5):304-317

Department of Diabetes, Endocrinology, Nutritional Medicine and Metabolism, Bern University Hospital, University of Bern, Bern, Switzerland. Electronic address:

There has been substantial progress in the knowledge of exercise and type 1 diabetes, with the development of guidelines for optimal glucose management. In addition, an increasing number of people living with type 1 diabetes are pushing their physical limits to compete at the highest level of sport. However, the post-exercise recovery routine, particularly with a focus on sporting performance, has received little attention within the scientific literature, with most of the focus being placed on insulin or nutritional adaptations to manage glycaemia before and during the exercise bout. Read More

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Post-resistance exercise photobiomodulation therapy has a more effective antioxidant effect than pre-application on muscle oxidative stress.

Photochem Photobiol Sci 2021 Apr 17. Epub 2021 Apr 17.

Universidade Nove de Julho, Programa de Pós-Graduação em Biofotônica Aplicada as Ciências da Saúde, São Paulo, SP, Brazil.

This study evaluated the effect of photobiomodulation therapy (PBMt) before or after a high-intensity resistance exercise (RE) session on muscle oxidative stress. Female Wistar rats were assigned to one of the following groups: Sham (non-exercised, undergoing placebo-PBMt); NLRE (exercised, undergoing placebo-PBMt); PBMt + RE (pre-exercise PBMt); RE + PBMt (post-exercise PBMt). The RE comprised four climbs bearing the maximum load with a 2 min rest between each climb. Read More

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Molecular mechanisms of physical exercise on depression in the elderly: a systematic review.

Mol Biol Rep 2021 Apr 17. Epub 2021 Apr 17.

Physical Education Department, Federal University of the Valleys of Jequitinhonha and Mucuri (UFVJM), Diamantina, MG, Brazil.

Depressive disorders are common among the elderly. Major depressive disorder will be one of the highest healthcare costs in middle and higher income countries by 2030. It is known that physical inactivity leads to negative effects on mental health in the elderly. Read More

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The vicious circle between physical, psychological, and physiological characteristics of shift work in nurses: a multidimensional approach.

Sleep Breath 2021 Apr 17. Epub 2021 Apr 17.

Department of Physical Education and Sport Science, University of Thessaly, Karies, 42100, Trikala, Thessaly, Greece.

Purpose: To compare physical, psychological, and physiological adaptations between rotating and morning shift health workers using objective and subjective approaches.

Methods: Forty nurses [n = 20 morning shift (MS) group; n = 20 rotating shift (RS) group] were evaluated for anthropometry, body composition, and handgrip strength. Quality of life, depression, fatigue, daytime sleepiness, and sleep quality were assessed with SF-36, Zung Self-Rating Depression Scale (SDS), Fatigue Severity Scale (FSS), Epworth Sleepiness Scale (ESS), and Pittsburgh Sleep Quality Index (PSQI), respectively. Read More

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The effect of acute low-load resistance exercise with the addition of blood flow occlusion on muscle function in boys and men.

Eur J Appl Physiol 2021 Apr 17. Epub 2021 Apr 17.

Department of Kinesiology, Faculty of Applied Health Sciences, Brock University, 1812 Sir Isaac Brock Way, St. Catharines, ON, L2S 3A1, Canada.

Purpose: In adults, low-load resistance training with blood flow occlusion (BFO) mimics strength increases that occur from high-load training, without the need to experience high mechanical stress. In view of child-adult differences in exercise responses, this study examined whether BFO during exercise elicits differential changes in maximal voluntary contraction (MVC) and electromyographical (EMG) activity in children and adults.

Methods: Sixteen men (24. Read More

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Anti-carcinogenic effects of exercise-conditioned human serum: evidence, relevance and opportunities.

Eur J Appl Physiol 2021 Apr 17. Epub 2021 Apr 17.

School of Biomedical, Nutritional and Sport Sciences, Faculty of Medical Sciences, Newcastle University Centre for Cancer, Newcastle University, Newcastle upon Tyne, UK.

Regular physical activity reduces the risk of several site-specific cancers in humans and suppresses tumour growth in animal models. The mechanisms through which exercise reduces tumour growth remain incompletely understood, but an intriguing and accumulating body of evidence suggests that the incubation of cancer cells with post-exercise serum can have powerful effects on key hallmarks of cancer cell behaviour in vitro. This suggests that exercise can impact tumour biology through direct changes in circulating proteins, RNA molecules and metabolites. Read More

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Implementation of a workplace physical activity intervention in child care: process evaluation results from the Care2BWell trial.

Transl Behav Med 2021 Apr 17. Epub 2021 Apr 17.

Department of Health Behavior, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Care2BWell was designed to evaluate the efficacy of Healthy Lifestyles (HL), a worksite health promotion intervention to increase child care workers' physical activity. The purpose of this study was to use process evaluation to describe the implementation of HL and determine if different levels of implementation are associated with changes in workers' physical activity. Data were collected from 250 workers randomized to HL, a 6 month, multilevel intervention that included an educational workshop followed by three 8 week campaigns that included self-monitoring and feedback, raffle incentive, social support, and center director coaching. Read More

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Improving the design of an oxidative stress sensing biosensor in yeast.

FEMS Yeast Res 2021 Apr 17. Epub 2021 Apr 17.

Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario, M5S 1A1, Canada.

Transcription factor (TF)-based biosensors have proven useful for increasing biomanufacturing yields, large-scale functional screening, and in environmental monitoring. Most yeast TF-based biosensors are built from natural promoters, resulting in large DNA parts retaining considerable homology to the host genome, which can complicate biological engineering efforts. There is a need to explore smaller, synthetic biosensors to expand the options for regulating gene expression in yeast. Read More

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Excessive expression of miR-1a by statin causes skeletal injury through targeting mitogen-activated protein kinase kinase kinase 1.

Aging (Albany NY) 2021 Apr 16;13. Epub 2021 Apr 16.

Department of Cardiology, Shandong Provincial Hospital, Shandong University, Jinan, China.

Backgrounds: A major side effect of statin, a widely used drug to treat hyperlipidemia, is skeletal myopathy through cell apoptosis. The aim of this study is to investigate the roles of microRNA in statin-induced injury.

Methods: Apolipoprotein E knockout (ApoE-/-) mice were administered with simvastatin (20 mg/kg/day) for 8 weeks. Read More

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Implementation of the Good Life with osteoArthritis in Denmark (GLA:D) Program across Canada for the Management of Hip and Knee Osteoarthritis.

Healthc Q 2021 Apr;24(1):54-59

A physiotherapist and the executive director of Bone and Joint Canada in Toronto, ON, where she leads system-improvement projects in orthopedics and arthritis. She is the clinical lead for the implementation of the GLA:D program across Canada. She can be contacted at

Good Life with osteoArthritis in Denmark (GLA:D®) is a program for the management of patients with hip and knee osteoarthritis (OA). Adapted for the Canadian population, the GLA:DTM Canada program implements evidence-based strategies to support the prevention, early diagnosis and effective management of hip and knee OA. GLA:D assists local communities in implementing OA strategies across the spectrum of disease severity. Read More

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Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.

Stress Health 2021 Apr 16. Epub 2021 Apr 16.

Global Medical Nutritionals, Consumer Healthcare, Sanofi-Aventis, Paris, France.

Magnesium status and vitamin B6 intake have been linked to mental health and/or quality of life (QoL). In an 8-week Phase IV randomised controlled study in individuals with low magnesemia and severe/extremely severe stress but who were otherwise healthy, greater stress reduction was achieved with magnesium combined with vitamin B6 than with magnesium alone. Here, we present a previously unreported secondary analysis of the effect of magnesium, with and without vitamin B6, on depression, anxiety, and QoL. Read More

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Neuronal androgen receptor is required for activity dependent enhancement of peripheral nerve regeneration.

Dev Neurobiol 2021 Apr 17. Epub 2021 Apr 17.

Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia, USA.

Neuronal activity after nerve injury can enhance axon regeneration and the restoration of function. The mechanism for this enhancement relies in part on hormone receptors, and we previously demonstrated that systemic androgen receptor antagonism blocked the effect of exercise or electrical stimulation on enhancing axon regeneration after nerve injury in both sexes. Here, we tested the hypothesis that the site of this androgen receptor signaling is both neuronal and involves the classical, genomic signaling pathway. Read More

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Social factors predicting improvement of frailty in community-dwelling older adults: Korean Frailty and Aging Cohort Study.

Geriatr Gerontol Int 2021 Apr 17. Epub 2021 Apr 17.

Center for Human-Caring Nurse Leaders for the Future by Brain Korea 21 (BK 21) four project, College of Nursing, Seoul National University, Seoul, Republic of Korea.

Aim: The study aimed to identify social factors predicting improvement of frailty in community-dwelling older adults after 2 years using a population-based cohort study.

Methods: We analyzed data from the 2016 and 2018 Korean Frailty and Aging Cohort Study. The participants of this study were 1428 community-dwelling older adults aged 70-84 years who were recruited from 10 medical centers across different regions. Read More

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A scoping review of workplace wellness audit tools assessing physical activity and sedentary behavior.

Health Promot J Austr 2021 Apr 16. Epub 2021 Apr 16.

Knowledge Resource Service, Alberta Health Services, Tom Baker Cancer Centre, Canada.

Background: Regular physical inactivity and excessive sedentary behaviour are public and population health concerns. The workplace is an ideal health promotion intervention setting to support employees, particularly office workers. Workplace assessments are a critical component of workplace health promotion programming. Read More

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Comparison of free-living physical activity data obtained from a Fitbit Zip, the Apple iPhone Health app and a modified Bouchard Activity Record.

Health Promot J Austr 2021 Apr 16. Epub 2021 Apr 16.

School of Population Health, UNSW Sydney, Australia.

Issue Addressed: Physical activity tracking devices have potential to improve public health, but their data needs to be reliable. No study has compared movement data between the Fitbit Zip, Apple iPhone Health app and physical activity records in a community setting over 10 days.

Methods: University students aged 18+ years wore both a Fitbit Zip and an iPhone at/near their right waist and completed a modified Bouchard Activity Record (BAR) for 10 days in a free-living setting. Read More

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Maximum dorsiflexion increases Achilles tendon force during exercise for midportion Achilles tendinopathy.

Scand J Med Sci Sports 2021 Apr 16. Epub 2021 Apr 16.

Department of Bioengineering, Imperial College London, London, United Kingdom.

Rehabilitation is an important treatment for non-insertional Achilles tendinopathy. To date, eccentric loading exercises (ECC) have been the predominant choice; however, mechanical evidence underlying their use remains unclear. Other protocols, such as heavy slow resistance loading (HSR), have shown comparable outcomes, but with less training time. Read More

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Barriers and facilitators of physical activity participation for people with disabilities: a parent's perspective.

Authors:
Cynthia Frisina

Dev Med Child Neurol 2021 Apr 16. Epub 2021 Apr 16.

Cerebral Palsy Foundation, New York, NY, USA.

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Physical capability, physical activity, and their association with femoral bone mineral density in adults aged 40 years and older: The Tromsø study 2015-2016.

Osteoporos Int 2021 Apr 16. Epub 2021 Apr 16.

Department of Chronic Diseases and Ageing, Norwegian Institute of Public Health, Marcus Thranes gate 6, 0473, Oslo, Norway.

Since muscles can influence bone growth and vice versa, we examined if level of physical activity and physical capability tests can predict areal bone mineral density (aBMD). Both high activity level and good test performance were associated with higher aBMD, especially in women.

Introduction: Muscle influences bone formation and vice versa. Read More

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