Neurology 2021 08 25;97(8):367-377. Epub 2021 Jun 25.
From the Department of Neurology (R.G.B., J.W.C.), University of Maryland, Baltimore; Department of Emergency Medicine (L.H.), Washington University, St. Louis, MO; Department of Clinical Sciences, Lund (A.L.), Lund University; Department of Neurology (A.G.L.), Skåne University Hospital, Lund, Sweden; Departments of Neurology (A.d.H.) and Health and Kinesiology (J.A.D., K.R.L.), University of Utah, Salt Lake City; Department of Neurology (S.C.C.), University of California, Los Angeles; California Rehabilitation Institute (S.C.C.), Los Angeles; and Departments of Neurology and Public Health Sciences (B.B.W.), University of Virginia, Charlottesville.
Global outcome measures that are widely used in stroke clinical trials, such as the modified Rankin Scale (mRS), lack sufficient detail to detect changes within specific domains (e.g., sensory, motor, visual, linguistic, or cognitive function). Read More