Behav Brain Res 2015 Jun 6;286:128-35. Epub 2015 Mar 6.
Department of Medical Neuroscience, 5850 College Street, PO Box 15000, Halifax, NS B3H 4R2, Canada; Department of Urologic Sciences, Gordon & Leslie Diamond Care Centre, 2775 Laurel St., University of British Columbia, Vancouver, BC V5Z 1M9, Canada; Australian Research Centre in Sex, Health and Society, La Trobe University 215 Franklin Street, Melbourne, Victoria 3000, Australia. Electronic address:
Androgen deprivation in males has detrimental effects on various tissues and bodily functions, some of which can be restored by estradiol (E2) administration. We investigated how the duration of androgen deprivation affects the autoregulation of estrogen receptors (ERs) levels in core brain areas associated with sexual behavior and cognition, as well as in pelvic floor muscles (PFM). We also measured c-Fos levels in brain areas associated with sexual behavior shortly after the rats mated. Read More