16,516 results match your criteria peroxide catalase


Doxycycline Hyclate Modulates Antioxidant Defenses, Matrix Metalloproteinases, and COX-2 Activity Accelerating Skin Wound Healing by Secondary Intention in Rats.

Oxid Med Cell Longev 2021 17;2021:4681041. Epub 2021 Apr 17.

Departament of Animal Biology, Federal University of Viçosa, Viçosa, Minas Gerais 36570-900, Brazil.

The main objective of this study was to investigate the action of doxycycline hyclate (Dx) in the skin wound healing process in Wistar rats. We investigated the effect of Dx on inflammatory cell recruitment and production of inflammatory mediators via and analysis. In addition, we analyzed neovascularization, extracellular matrix deposition, and antioxidant potential of Dx on cutaneous repair in Wistar rats. Read More

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Oxidative stress induced by NOX2 contributes to neuropathic pain via plasma membrane translocation of PKCε in rat dorsal root ganglion neurons.

J Neuroinflammation 2021 May 6;18(1):106. Epub 2021 May 6.

Center for Experimental Medicine, the First Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China.

Background: Nicotinamide adenine dinucleotide phosphate oxidase 2 (NOX2)-induced oxidative stress, including the production of reactive oxygen species (ROS) and hydrogen peroxide, plays a pivotal role in neuropathic pain. Although the activation and plasma membrane translocation of protein kinase C (PKC) isoforms in dorsal root ganglion (DRG) neurons have been implicated in multiple pain models, the interactions between NOX2-induced oxidative stress and PKC remain unknown.

Methods: A spared nerve injury (SNI) model was established in adult male rats. Read More

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UV-B exposure and exogenous hydrogen peroxide application lead to cross-tolerance toward drought in Nicotiana tabacum L.

Physiol Plant 2021 May 4. Epub 2021 May 4.

Biosystems Engineering, School of Engineering, Autonomous University of Queretaro-Campus Amazcala, Querétaro, Mexico.

Acclimation of plants to water deficit involves biochemical and physiological adjustments. Here, we studied how UV-B exposure and exogenously applied hydrogen peroxide (H O ) potentiates drought tolerance in tobacco (Nicotiana tabacum L. cv. Read More

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Effect of lycopene on AsO induced oxidative stress in SH-SY5Y cells.

Mol Biol Rep 2021 May 4. Epub 2021 May 4.

Department of Biochemistry, Faculty of Medicine, İstanbul Medeniyet University, İstanbul, Turkey.

It is known that oxidative stress may cause neuronal injury and several experimental models showed that AsO exposure causes oxidative stress. Lycopene, a carotenoid, has been shown to have protective effect in neurological disease models due to antioxidant activity, but its effect on AsO-induced neurotoxicity is not identified yet. The aim of this study is to investigate the effects of lycopene on AsO-induced neuronal damage and the related mechanisms. Read More

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The alveolar epithelial cells are involved in pulmonary vascular remodeling and constriction of hypoxic pulmonary hypertension.

Respir Res 2021 May 4;22(1):134. Epub 2021 May 4.

Department of Pathophysiology, School of Basic Medicine, Fourth Military Medical University, 169 Changle Western Street, Xi'an, Shaanxi, 710032, People's Republic of China.

Background: Hypoxic pulmonary hypertension (HPH) is a common type of pulmonary hypertension and characterized by pulmonary vascular remodeling and constriction. Alveolar epithelial cells (AECs) primarily sense alveolar hypoxia, but the role of AECs in HPH remains unclear. In this study, we explored whether AECs are involved in pulmonary vascular remodeling and constriction. Read More

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Oxidative and antioxidative stress markers in dry eye disease: A systematic review and meta-analysis.

Acta Ophthalmol 2021 May 2. Epub 2021 May 2.

Université Clermont Auvergne, CNRS, LaPSCo, Physiological and Psychosocial Stress, CHU Clermont-Ferrand, University Hospital of Clermont-Ferrand, Preventive and Occupational Medicine, Witty Fit, Clermont-Ferrand, France.

Purpose: To conduct a systematic review and meta-analysis on the levels of oxidative stress markers and antioxidants in dry eye disease (DED) compared with healthy subject.

Method: The PubMed, Cochrane Library, Embase, Science Direct and Google Scholar databases were searched on 10 January 2021 for studies reporting oxidative and antioxidative stress markers in DED and healthy controls. Main meta-analysis was stratified by type of biomarkers, type of samples (tears, conjunctival cells or biopsies), Sjögren's syndrome (SS) (patients with or without SS) and by geographical zones (Asia or Europe). Read More

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Combined treatment with dissolved hydrogen molecule and platinum nanocolloid exerts carcinostatic/carcinocidal effects by increasing hydrogen peroxide generation and cell death in the human gastric cancer cell line NUGC-4.

Free Radic Res 2021 Apr 30:1-10. Epub 2021 Apr 30.

Laboratory of Bioscience and Biotechnology for Cell Function Control, Faculty of Life and Environmental Sciences, Prefectural University of Hiroshima, Shobara, Japan.

Many studies have shown that redox regulation is an effective therapeutic strategy for different types of cancer. We have previously demonstrated that combined treatment with dissolved hydrogen molecule (H) and platinum nanocolloid (Pt-nc) has carcinostatic effects and that increased intracellular reactive oxygen species (ROS) levels were closely associated with carcinostatic effects in Ehrlich mouse ascites tumor cells. However, it is unknown whether combined treatment-induced ROS generation can occur in human cancer cells. Read More

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Exogenous Sodium Nitroprusside Mitigates Salt Stress in Lentil ( Medik.) by Affecting the Growth, Yield, and Biochemical Properties.

Molecules 2021 Apr 28;26(9). Epub 2021 Apr 28.

Department of Agronomy, Faculty of Agriculture, Kafrelsheikh University, Kafrelsheikh 33156, Egypt.

Soil salinity disrupts the physiological and biochemical processes of crop plants and ultimately leads to compromising future food security. Sodium nitroprusside (SNP), a contributor to nitric oxide (NO), holds the potential to alleviate abiotic stress effects and boost tolerance in plants, whereas less information is available on its role in salt-stressed lentils. We examined the effect of exogenously applied SNP on salt-stressed lentil plants by monitoring plant growth and yield-related attributes, biochemistry of enzymes (superoxide dismutase (SOD), catalase (CAT), and peroxidase (POD)) amassing of leaf malondialdehyde (MDA) and hydrogen peroxide (HO). Read More

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BTH Treatment Delays the Senescence of Postharvest Pitaya Fruit in Relation to Enhancing Antioxidant System and Phenylpropanoid Pathway.

Foods 2021 Apr 13;10(4). Epub 2021 Apr 13.

South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China.

The plant resistance elicitor Benzo (1,2,3)-thiadiazole-7-carbothioic acid S-methyl ester (BTH) can enhance disease resistance of harvested fruit. Nonetheless, it is still unknown whether BTH plays a role in regulating fruit senescence. In this study, exogenous BTH treatment efficiently delayed the senescence of postharvest pitaya fruit with lower lipid peroxidation level. Read More

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Catalase (CAT) Gene Family in Rapeseed ( L.): Genome-Wide Analysis, Identification, and Expression Pattern in Response to Multiple Hormones and Abiotic Stress Conditions.

Int J Mol Sci 2021 Apr 20;22(8). Epub 2021 Apr 20.

College of Agriculture, Engineering Research Center of Ecology and Agricultural Use of Wetland of Ministry of Education, Yangtze University, Jingzhou 434025, China.

Catalase (CAT) is an antioxidant enzyme expressed by the gene family and exists in almost all aerobic organisms. Environmental stresses induce the generation of reactive oxygen species (ROS) that eventually hinder plant growth and development. The CAT enzyme translates the hydrogen peroxide (HO) to water (HO) and reduce the ROS levels to shelter the cells' death. Read More

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Relationship between Oxidative Stress and Imatinib Resistance in Model Chronic Myeloid Leukemia Cells.

Biomolecules 2021 Apr 20;11(4). Epub 2021 Apr 20.

Laboratory of Medical Genetics, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143 Street, 90-236 Lodz, Poland.

Chronic myeloid leukemia (CML) develops due to the presence of the BCR-ABL1 protein, a target of tyrosine kinase inhibitors (TKIs), such as imatinib (IM), used in a CML therapy. CML eradication is a challenge due to developing resistance to TKIs. BCR-ABL1 induces endogenous oxidative stress leading to genomic instability and development of TKI resistance. Read More

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Systemic Resistance in Chilli Pepper against Anthracnose (Caused by ) Induced by , and .

J Fungi (Basel) 2021 Apr 16;7(4). Epub 2021 Apr 16.

Laboratory of Mycopathology and Microbial Technology, Centre of Advanced Study in Botany, Institute of Science, Banaras Hindu University, Varanasi 221005, Uttar Pradesh, India.

In the present study, , and were appraised as potential biocontrol agents that induce resistance in chilli () against the devastating pathogen which causes anthracnose. Bright-field and scanning electron micrographs showed the hyphal degradation, lysis, and abnormal swelling in against in a dual plate assay. Under greenhouse conditions, chilli seeds pretreated with and + by soil soak method inflicted an induced systemic resistance (ISR) in chilli against a -challenged condition. Read More

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Modulation of the Antioxidant Defense System by Exogenous l-Glutamic Acid Application Enhances Salt Tolerance in Lentil ( Medik.).

Biomolecules 2021 Apr 16;11(4). Epub 2021 Apr 16.

Laboratory of Plant Stress Responses, Faculty of Agriculture, Kagawa University, Ikenobe 2393, Miki-Cho, Kita Gun, Kagawa 761-0795, Japan.

Salt stress greatly disturbs the growth, morpho-physiological, and biochemical performance of plants. However, different physiological processes and acclimation mechanisms can be induced under stress, while some of them can be modulated by the appropriate chemical stimulus. The objective of this study was to evaluate the impact of exogenous pretreatment with 10 mM l-glutamic acid (l-Glu) on the physiological and biochemical parameters of lentil ( Medik. Read More

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Catalase Modulates the Radio-Sensitization of Pancreatic Cancer Cells by Pharmacological Ascorbate.

Antioxidants (Basel) 2021 Apr 16;10(4). Epub 2021 Apr 16.

Free Radical and Radiation Biology Program, Department of Radiation Oncology, The University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.

Pancreatic cancer cells (PDACs) are more susceptible to an oxidative insult than normal cells, resulting in greater cytotoxicity upon exposure to agents that increase pro-oxidant levels. Pharmacological ascorbate (P-AscH), i.e. Read More

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Cerium Oxide Nanoparticles: A New Therapeutic Tool in Liver Diseases.

Antioxidants (Basel) 2021 Apr 24;10(5). Epub 2021 Apr 24.

Service of Biochemistry and Molecular Genetics, Hospital Clinic Universitari, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d'Investigacions, Biomèdiques August Pi i Sunyer (IDIBAPS), 08905 Barcelona, Spain.

Oxidative stress induced by the overproduction of free radicals or reactive oxygen species (ROS) has been considered as a key pathogenic mechanism contributing to the initiation and progression of injury in liver diseases. Consequently, during the last few years antioxidant substances, such as superoxide dismutase (SOD), resveratrol, colchicine, eugenol, and vitamins E and C have received increasing interest as potential therapeutic agents in chronic liver diseases. These substances have demonstrated their efficacy in equilibrating hepatic ROS metabolism and thereby improving liver functionality. Read More

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Ameliorative Effects of Exogenous Proline on Photosynthetic Attributes, Nutrients Uptake, and Oxidative Stresses under Cadmium in Pigeon Pea ( L.).

Plants (Basel) 2021 Apr 19;10(4). Epub 2021 Apr 19.

Key Laboratory of Plant Ecology, Northeast Forestry University, Harbin 150040, China.

Proline plays a significant role in the plant response to stress conditions. However, its role in alleviating metal-induced stresses remains elusive. We conducted an experiment to evaluate the ameliorative role of exogenous proline on cadmium-induced inhibitory effects in pigeon pea subjected to different Cd treatments (4 and 8 mg/mL). Read More

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The Effect of and Essential Oils on Biochemical Markers of Oxidative Stress in Aphids.

Insects 2021 Apr 17;12(4). Epub 2021 Apr 17.

Department of Biotechnology, Institute of Biology and Biotechnology, University of Rzeszow, Zelwerowicza 8B, 35-601 Rzeszow, Poland.

This study investigated the toxicity of essential oils (EOs) from (L.) and (L.) towards the green peach aphid (Sulzer) and the bird cherry-oat aphid (L. Read More

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Exogenous Gibberellic Acid or Dilute Bee Honey Boosts Drought Stress Tolerance in by Rebalancing Osmoprotectants, Antioxidants, Nutrients, and Phytohormones.

Plants (Basel) 2021 Apr 11;10(4). Epub 2021 Apr 11.

Horticulture Department, Faculty of Agriculture, Fayoum University, Fayoum 63514, Egypt.

The use of growth regulators such as gibberellic acid (GA) and biostimulants, including diluted bee honey (Db-H) can improve drought tolerance in many crops, including the faba bean ( L.). Db-H contains high values of osmoprotectants, mineral nutrients, vitamins, and many antioxidants making it an effective growth regulator against environmental stress effects. Read More

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Antioxidant Enzymatic Activities and Growth Response of Quinoa ( Willd) to Exogenous Selenium Application.

Plants (Basel) 2021 Apr 7;10(4). Epub 2021 Apr 7.

Department of Plant Production, King Saud University, College of Food and Agriculture Sciences, Riyadh 11461, Saudi Arabia.

Selenium is a trace element essential to many organisms, including higher plants. At low concentrations, it enhances growth and development; however, it is toxic at high concentrations. The development of crops with proper levels of selenium will be worth for both nutrition and Se-based therapeutics. Read More

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Zinc Oxide Nanoparticles and Zinc Sulfate Impact Physiological Parameters and Boosts Lipid Peroxidation in Soil Grown Coriander Plants ().

Molecules 2021 Apr 1;26(7). Epub 2021 Apr 1.

Centro de Capacitación y Desarrollo en Tecnología de Semillas, Departamento de Fitomejoramiento, Universidad Autónoma Agraria Antonio Narro, Saltillo C.P. 25315, Coahuila, Mexico.

The objective of this study was to determine the oxidative stress and the physiological and antioxidant responses of coriander plants () grown for 58 days in soil with zinc oxide nanoparticles (ZnO NPs) and zinc sulfate (ZnSO) at concentrations of 0, 100, 200, 300, and 400 mg of Zn/kg of soil. The results revealed that all Zn compounds increased the total chlorophyll content (CHLt) by at least 45%, compared to the control group; however, with 400 mg/kg of ZnSO, chlorophyll accumulation decreased by 34.6%. Read More

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Cerium oxide nanomaterial with dual antioxidative scavenging potential: Synthesis and characterization.

J Biomater Appl 2021 Apr 28:8853282211013451. Epub 2021 Apr 28.

University of Central Florida, Advanced Materials Processing and Analysis Center, Orlando, FL, USA.

Many studies have linked reactive oxygen species (ROS) to various diseases. Biomedical research has therefore sought a way to control and regulate ROS produced in biological systems. In recent years, cerium oxide nanoparticles (nanoceria, CNPs) have been pursued due to their ability to act as regenerative ROS scavengers. Read More

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Rutin maintains redox balance to relieve oxidative stress induced by TBHP in nucleus pulposus cells.

In Vitro Cell Dev Biol Anim 2021 Apr 28. Epub 2021 Apr 28.

School of Traditional Chinese Medicine, Southern Medical University, 1063 Shatai Road, Guangzhou, 510515, Guangdong, China.

Rutin is well known for its anti-inflammatory and antioxidant properties against oxidative stress. However, its protective function in nucleus pulposus cells (NPCs) remains unclear. This study was aimed to explore the effects of rutin on oxidative stress in NPCs. Read More

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Gamma-aminobutyric acid improves phenanthrene phytotoxicity tolerance in cucumber through the glutathione-dependent system of antioxidant defense.

Ecotoxicol Environ Saf 2021 Jul 24;217:112254. Epub 2021 Apr 24.

College of Horticulture, Henan Agricultural University, Zhengzhou 450002, PR China. Electronic address:

Phenanthrene (PHE), a typical organic pollutant, has drawn attention in recent years due to its toxicity to plants and human health. Gamma-aminobutyric acid (GABA) induce plant tolerance to diverse stresses. However, the role and regulatory mechanisms of GABA in PHE stress responses in plants remains largely uncharacterized. Read More

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Peroxiredoxin 2 oxidation reveals hydrogen peroxide generation within erythrocytes during high-dose vitamin C administration.

Redox Biol 2021 Apr 17;43:101980. Epub 2021 Apr 17.

Centre for Free Radical Research, Department of Pathology & Biomedical Science, University of Otago, Christchurch, New Zealand. Electronic address:

Intravenous infusion of high dose (>10 g) vitamin C (IVC) is a common alternative cancer therapy. IVC results in millimolar levels of circulating ascorbate, which is proposed to generate cytotoxic quantities of HO in the presence of transition metal ions. In this study we report on the in vitro and in vivo effects of millimolar ascorbate on erythrocytes. Read More

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Hydrogen-rich water alleviates programmed cell death induced by GA in wheat aleurone layers by modulation of reactive oxygen species metabolism.

Plant Physiol Biochem 2021 Jun 20;163:317-326. Epub 2021 Apr 20.

China Tobacco Gene Research Center, Zhengzhou Tobacco Research Institute of China National Tobacco Corporation, Zhengzhou, 450001, China. Electronic address:

Hydrogen gas (H) has been recently regarded as a novel gaseous signaling molecule that performs multiple functional roles in plant. Here, we demonstrate that hydrogen rich water (HRW)-an experimentally tractable reagent to assess the effects of the H significantly delays wheat aleurone layer programmed cell death (PCD) induced by gibberellic acid (GA). Endogenous H production exhibited lower level in aleurone layers under GA treatment, whereas the H production was apparently increased under abscisic acid (ABA) treatment. Read More

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Effect of Low Temperature and High Humidity Stress on Physiology of Cucumber at Different Leaf Stages.

Plant Biol (Stuttg) 2021 Apr 26. Epub 2021 Apr 26.

College of Horticulture, Northwest A&F University, Yangling, 71210, China.

Low temperature (LT) and high humidity (HH) are important environmental factors in green house and plastic tunnel during cold season that hamper plant growth and development. Here, we studied the effect of LT (day/night: 9/5°C with 25/18°C as the control) and HH (95% with 80% as the control) on cucumber young plants at 2, 4 or 6 leaf stage. LT and HH stress resulted in decline of shoot, root and total fresh and dry weight, and decreased net photosynthesis (Pn), stomatal conductance (Gs), transpiration rate (Tr), photochemical efficiency (Fv/Fm), photochemical quenching (qP), electron transport rate (ETR) and chlorophyll pigments, and increased malondialdehyde (MDA), hydrogen peroxide (H O ), superoxide (O ), non-photochemical quenching coefficient (NPQ) and intercellular CO rate (Ci) as compared to the control at 2 leaf stage. Read More

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[Effects of potassium-solubilizing bacteria promoting the growth of seedlings under salt stress.]

Ying Yong Sheng Tai Xue Bao 2021 Apr;32(4):1289-1297

College of Biological Science and Engineering, North Minzu University, Yinchuan 750021, China.

We investigated the effects of potassium-releasing bacteria on physiological and bioche-mical characteristics of (Cultivar Ningqi 1) under salt stress, with an experiment with treatments following randomized block design. The treatments included control (CK), 100 mmol·L NaCl stress (NaCl), 100 mmol·LNaCl stress+KSBGY01 bacteria (NaCl-M1), 100 mmol·LNaCl stress+KSBGY02 bacteria (NaCl-M2), and 100 mmol·LNaCl stress+KSBGY01+KSBGY02 (NaCl-M3). We measued chlorophyll content, polyphenol content, superoxide anion (O) content, hydrogen peroxide (HO) content, soluble sugar content, antioxidant enzyme activity and sucrose metabolic enzyme activity of seedlings. Read More

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Protective Effect of Triphala against Oxidative Stress-Induced Neurotoxicity.

Biomed Res Int 2021 7;2021:6674988. Epub 2021 Apr 7.

Laboratory of Cell and Molecular Biology, Beijing Tibetan Hospital, China Tibetology Research Center, 218 Anwaixiaoguanbeili Street, Chaoyang, Beijing 100029, China.

Background: Oxidative stress is implicated in the progression of many neurological diseases, which could be induced by various chemicals, such as hydrogen peroxide (HO) and acrylamide. Triphala is a well-recognized Ayurvedic medicine that possesses different therapeutic properties (e.g. Read More

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Protective Effect of cv. Fubaiju Hot-Water Extracts Against ARPE-19 Cell Oxidative Damage by Activating PI3K/Akt-Mediated Nrf2/HO-1 Signaling Pathway.

Front Nutr 2021 7;8:648973. Epub 2021 Apr 7.

China-Canada Joint Lab of Food Nutrition and Health (Beijing), Beijing Technology & Business University (BTBU), Beijing, China.

cv. Fubaiju is a kind of widely consumed herb tea with multiple health benefits. The present study was aimed to evaluate the protective capacity of cv. Read More

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