60,794 results match your criteria peroxidase activity

A crucial review on polycyclic aromatic Hydrocarbons - Environmental occurrence and strategies for microbial degradation.

Chemosphere 2021 Apr 28;280:130608. Epub 2021 Apr 28.

Department of Microbiology, Alagappa University, Karaikudi, Tamil Nadu, India. Electronic address:

Over the last century, contamination of polycyclic aromatic hydrocarbons (PAHs) has risen tremendously due to the intensified industrial activities like petrochemical, pharmaceutical, insecticides and fertilizers applications. PAHs are a group of organic pollutants with adverse effects on both humans and the environment. These PAHs are widely distributed in various ecosystems including air, soil, marine water and sediments. Read More

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Roles of selenium in mineral plant nutrition: ROS scavenging responses against abiotic stresses.

Plant Physiol Biochem 2021 Apr 29;164:27-43. Epub 2021 Apr 29.

Universidade Estadual Paulista "Júlio de Mesquita Filho" (UNESP), Rua Domingos da Costa Lopes 780, Postal Code 17602-496, Tupã, SP, Brazil. Electronic address:

Agronomic biofortification of crops with selenium (Se) is an important strategy to minimize hidden hunger and increase nutrient intake in poor populations. Selenium is an element that has several physiological and biochemical characteristics, such as the mitigation of different types of abiotic stress. Selenoproteins act as powerful antioxidants in plant metabolism through the glutathione peroxidase (GSH) pathway, and provide an increased activity for enzymatic (SOD, CAT, and APX) and non-enzymatic (ascorbic acid, flavonoids, and tocopherols) compounds that act in reactive oxygen species (ROS) scavenging system and cell detoxification. Read More

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Proteomic analysis of liver tissues in chicken embryo at Day 16 and Day 20 reveals antioxidant mechanisms.

J Proteomics 2021 May 4:104258. Epub 2021 May 4.

College of Food and Biological Engineering, Hefei University of Technology, 193 Tunxi Road, Hefei, Anhui 230009, PR China. Electronic address:

To investigate the mechanisms of the defense system and antioxidant defense system during chicken embryo development, protein profiling of liver tissues in chicken embryo at Day 16 and Day 20 was conducted. TMT was used to analyze the liver tissues proteomes with significantly different activity of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in chicken embryo. PRM was operated to validate the target differentially abundant proteins (DAPs) using the same samples. Read More

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A green and facile approach to a graphene-based peroxidase-like nanozyme and its application in sensitive colorimetric detection of L-cysteine.

Anal Bioanal Chem 2021 May 7. Epub 2021 May 7.

CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Anhui Key Laboratory of Environmental Toxicology and Pollution Control Technology, Hefei Institute of IntelligentAgriculture, Institute of Intelligent Machines,Hefei Institutes of Physical Science, Chinese Academy of Sciences (CAS), Hefei, 230031, Anhui, China.

A facile and green approach to the preparation of peroxidase-like nanozymes by reducing and functionalizing graphene oxide (rGO) with Ganoderma polysaccharide (GP) has been achieved in this work. Our results showed that the as-fabricated nanozyme, namely rGO-GP, possessed the excellent property of simulating peroxidase with higher catalytic activity compared with GO or rGO obtained by using chitosan, which may be due to the better dispersion of rGO-GP in the solution. Steady-state kinetics studies further showed that the catalytic process conformed to Michaelis-Menten equation and ping-pong mechanism. Read More

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pH induced conformational alteration in human peroxiredoxin 6 might be responsible for its resistance against lysosomal pH or high temperature.

Sci Rep 2021 May 6;11(1):9657. Epub 2021 May 6.

Dr. B. R. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, 110007, India.

Peroxiredoxin 6 (Prdx6), the ubiquitously expressed enzyme belonging to the family of peroxidases, namely, peroxiredoxins, exhibits a unique feature of functional compartmentalization within cells. Whereas, the enzyme localized in cytosol shows glutathione peroxidase activity, its lysosomal counterpart performs calcium independent phospholipase A2 (aiPLA2) activity. Like any true moonlighting protein, these two activities of Prdx6 are mutually exclusive of each other as a function of the pH of the cellular compartments. Read More

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Microplastic intake and enzymatic responses in Mytilus galloprovincialis reared at the vicinities of an aquaculture station.

Chemosphere 2021 Apr 24;280:130575. Epub 2021 Apr 24.

Instituto Español de Oceanografía, Centro Oceanografico de Baleares, Muelle de Poniente S/n, 07015, Palma de Mallorca, Balearic Islands, Spain.

Aquaculture is a potential source of microplastics (MPs) that could be strong stressors for marine organisms. In this study, we evaluated the effects of MPs derived from aquaculture in antioxidant defences and oxidative stress markers in gills of Mytilus galloprovincialis. Mussels were distributed in three areas with different impacts: inside aquaculture cages, Control 1 (located inside Andratx harbour) and Control 2 (located in a no-anthropized area). Read More

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Capsulation of AuNCs with AIE Effect into Metal-Organic Framework for the Marriage of a Fluorescence and Colorimetric Biosensor to Detect Organophosphorus Pesticides.

Anal Chem 2021 May 6. Epub 2021 May 6.

Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, People's Republic of China.

Organophosphorus pesticides (OPs) can inhibit the activity of acetylcholinesterase (AChE) to induce neurological diseases. It is significant to exploit a rapid and sensitive strategy to monitor OPs. Here, a metal-organic framework (MOF) acted as a carrier to encapsulate AuNCs, which can limit the molecular motion of AuNCs, trigger the aggregation-induced emission (AIE) effect, and exhibit a strong fluorescence with a fluorescence lifetime and quantum yield of 6. Read More

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2D bimetallic Ni/Fe MOF nanosheet composites as a peroxidase-like nanozyme for colorimetric assay of multiple targets.

Anal Methods 2021 May;13(17):2066-2074

Key Laboratory of Luminescence Analysis and Molecular Sensing, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.

In this contribution, 2D Ni/Fe MOF nanosheets were synthesized by a simple two-step ultrasound strategy at room temperature, i.e. the 2D Ni-MOF with a lamellar structure was first synthesized by the top-down ultrasonic assisted stripping route, followed by introducing Fe3+ ions as a metal node and terephthalic acid as an organic ligand to form 2D Ni/Fe MOF nanosheets that exhibited weak oxidase-like and strong peroxidase-like properties. Read More

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Effect of dietary flaxseed meal supplemented with dried tomato and grape pomace on performance traits and antioxidant status of laying hens.

Anim Biotechnol 2021 May 6:1-8. Epub 2021 May 6.

Department of DETO - Section of Veterinary Science and Animal Production, University of Bari "Aldo Moro", Valenzano, Italy.

This study was carried out to determine the effect of dietary flaxseed meal (FSM) supplemented with dried tomato pomace (DTP) and dried grape pomace (DGP) on performance, egg quality, biochemical parameters traits and antioxidant status of laying hens. Birds (1825 ± 87 g of body weight) were divided into 12 dietary groups with six replicates per group (eight birds per replicate), under a completely randomized design with factorial arrangement 2 × 3 × 2 consisted of two levels of DTP (0 and 15%), three FSM levels (0, 4 and 8%) and two levels of DGP (0 and 5%). As a result of this study, there were no significant differences in egg production and weight as well in feed conversion ratio (FCR) among treatments ( > 0. Read More

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Potential and safe utilization of Fly ash as fertilizer for Pisum sativum L. Grown in phytoremediated and non-phytoremediated amendments.

Environ Sci Pollut Res Int 2021 May 5. Epub 2021 May 5.

Department of Civil and Environmental Engineering, Birla Institute of Technology, Mesra, Ranchi, Jharkhand, 835215, India.

The present study focuses on the possibility of applying fly ash to agricultural fields for enhancing the production of agricultural crops. In this study, Pisum sativum L. was grown from germination stage to maturation stage in phytoremediated and non-phytoremediated or raw fly ash-amended soil. Read More

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Expression of Arabidopsis Ornithine Aminotransferase (AtOAT) encoded gene enhances multiple abiotic stress tolerances in wheat.

Plant Cell Rep 2021 May 5. Epub 2021 May 5.

Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100081, People's Republic of China.

Key Message: The drought and salt tolerances of wheat were enhanced by ectopic expression of the Arabidopsis ornithine aminotransferase (AtOAT) encoded gene. The OAT was confirmed to play a role in proline biosynthesis in wheat. Proline (Pro) accumulation is a common response to both abiotic and biotic stresses in plants. Read More

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Impact of citrus flavonoid supplementation on inflammation in lipopolysaccharide-induced periodontal disease in mice.

Food Funct 2021 May 5. Epub 2021 May 5.

Department of Physiology and Pathology, School of Dentistry, São Paulo State University (Unesp), Araraquara, São Paulo, Brazil.

In general, the consumption of flavonoid-rich foods may influence the control/dysregulation of the magnitude and duration of inflammation and oxidative stress, which are known to contribute to multiple pathologies. Information regarding the impact of citrus flavonoid dietary supplementation on periodontal disease is still scarce. Herein, we investigated whether a diet supplemented with eriocitrin and eriodictyol could alter the course of the inflammatory response associated with LPS-induced periodontal disease in mice. Read More

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UV-B exposure and exogenous hydrogen peroxide application lead to cross-tolerance toward drought in Nicotiana tabacum L.

Physiol Plant 2021 May 4. Epub 2021 May 4.

Biosystems Engineering, School of Engineering, Autonomous University of Queretaro-Campus Amazcala, Querétaro, Mexico.

Acclimation of plants to water deficit involves biochemical and physiological adjustments. Here, we studied how UV-B exposure and exogenously applied hydrogen peroxide (H O ) potentiates drought tolerance in tobacco (Nicotiana tabacum L. cv. Read More

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Preventive effect of Bacillus mojavensis levan against carbon tetrachloride and cisplatin toxicity: in vivo study.

Environ Sci Pollut Res Int 2021 May 5. Epub 2021 May 5.

Laboratory of Plants Improvement and Valorization of Agroressources, National School of Engineering of Sfax (ENIS), University of Sfax, 3038, Sfax, Tunisia.

This study is the first to investigate the hepato- and nephron-preventive effect of levan from Bacillus mojavensis (BM-levan) against toxicity induced by carbon tetrachloride (CCl) and cisplatin. Thirty-six male albino rats weighing between 230 and 250 g were used for this experiment. The groups received multiples doses of BM-levan and were compared to the untreated group. Read More

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Physiological and biochemical responses of two precious Carpinus species to high-concentration NO stress and their natural recovery.

Sci Rep 2021 May 4;11(1):9500. Epub 2021 May 4.

College of Forestry, Co-Innovation Center for Sustainable Forestry in Southern China, Nanjing Forestry of University, Nanjing, 210037, China.

Carpinus betulus and Carpinus putoensis are precious species in the world. Studies on the ecosystem function of the two species are rare. This study investigated the physiological and biochemical responses of C. Read More

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Genetically-determined variations of are associated with antioxidant, muscular, and lipid biomarkers in response to Brazil nut consumption by patients using statins.

Br J Nutr 2021 May 5:1-21. Epub 2021 May 5.

Department of Health Sciences, Division of Nutrition and Metabolism, Ribeirão Preto Medical School, University of São Paulo - FMRP/USP, Brazil.

Several single nucleotide polymorphisms (SNPs) could indirectly, as well directly, influence metabolic parameters related to health effects in response to selenium (Se) supplementation. This study aimed to investigate whether the selenoprotein SNPs were associated with the response of Se status biomarkers to the Brazil nut consumption in patients using statins, and if the variation in Se homeostasis could affect antioxidant protection, lipid profile, muscle homeostasis, and selenoproteins mRNA. The study was performed in the Ribeirão Preto Medical School University Hospital. Read More

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Peroxidase Enzyme Fractions as Markers of Somatic Embryogenesis Capacities in Olive ( L.).

Plants (Basel) 2021 Apr 29;10(5). Epub 2021 Apr 29.

Laboratoire d'Agroalimentaire, Biotechnologies et Valorisation des Bio-Ressources Végétales, Faculté des Sciences Semlalia, Université Cadi Ayyad, BP 2390, Marrakech 40000, Morocco.

As part of the search for biochemical markers of somatic embryogenesis in tissue cultures of olive ( L.), peroxidases (POXs) in both the soluble and ionically wall-bound fractions were studied in two reputed olive cultivars (cvs.): "Picholine Marocaine" and "Dahbia". Read More

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Alteration of the Immune Response and the Microbiota of the Skin during a Natural Infection by in European Seabass ().

Microorganisms 2021 Apr 29;9(5). Epub 2021 Apr 29.

Immunobiology for Aquaculture Group, Department of Cell Biology and Histology, Faculty of Biology, Campus Regional de Excelencia Internacional "Campus Mare Nostrum", University of Murcia, 30100 Murcia, Spain.

Disease outbreaks continue to represent one of the main bottlenecks for the sustainable development of the aquaculture industry. In marine aquaculture, many species from the genus are serious opportunistic pathogens responsible for significant losses to producers. In this study, the effects on the immune response and the skin microbiota of European sea bass () were studied after a natural disease outbreak caused by . Read More

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Potential Use of Amla ( L.) Fruit Extract to Protect Skin Keratinocytes from Inflammation and Apoptosis after UVB Irradiation.

Antioxidants (Basel) 2021 Apr 29;10(5). Epub 2021 Apr 29.

Department of Pharmacology, Faculty of Medicine, Srinakharinwirot University, Bangkok 10110, Thailand.

Ultraviolet B (UVB) exposure is the primary risk factor for the deadliest type of skin cancer-melanoma. Incorporating natural antioxidants in skin protection products is currently a favored research theme. For this study, we selected L. Read More

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Structural determinants of multimerization and dissociation in 2-Cys peroxiredoxin chaperone function.

Structure 2021 Apr 28. Epub 2021 Apr 28.

Department of Chemistry and Molecular Biology, University of Gothenburg, 405 30 Göteborg, Sweden; Department of Biology and Biological Engineering, Chalmers University of Technology, 405 30 Göteborg, Sweden. Electronic address:

Peroxiredoxins (PRDXs) are abundant peroxidases present in all kingdoms of life. Recently, they have been shown to also carry out additional roles as molecular chaperones. To address this emerging supplementary function, this review focuses on structural studies of 2-Cys PRDX systems exhibiting chaperone activity. Read More

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Alteration in antioxidant status in slow and fast alleles of EPHX1 gene polymorphisms among wood workers.

Environ Sci Pollut Res Int 2021 May 3. Epub 2021 May 3.

Department of Environmental and Occupational Medicine, Environmental Research Division, National Research Centre, Dokki, Giza, Egypt.

Occupational wood dust exposure may be associated with various health effects, especially in wood industry. These effects may be due to inducing oxidative stress which is related to inflammations. Biochemical assessment of antioxidant enzyme activities illustrated role of oxidative stress (OS) on its depletion. Read More

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DNA damage and biochemical responses in estuarine bivalve Donax incarnatus (Gmelin, 1791) exposed to sub-lethal concentrations of an organophosphate pesticide monocrotophos.

Environ Monit Assess 2021 May 3;193(6):317. Epub 2021 May 3.

Department of Zoology, Goa University, University Road, Taleigao, Goa, 403206, India.

Monocrotophos (MCP) is a highly toxic and broad-spectrum pesticide extensively used for agricultural and household purposes. The present study was aimed to evaluate the genotoxicity and alterations in the biochemical and physiological conditions induced by monocrotophos in a non-target organism, an estuarine bivalve, Donax incarnatus. The bivalves were exposed to three sub-lethal concentrations (6. Read More

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Mitigation of bacterial spot disease induced biotic stress in Capsicum annuum L. cultivars via antioxidant enzymes and isoforms.

Sci Rep 2021 May 3;11(1):9445. Epub 2021 May 3.

Department of Soil Science, Faculty of Agricultural Sciences and Technology, Bahauddin Zakariya University, Multan, 60800, Pakistan.

Bacterial spot, caused by a group of Xanthomonads (Xanthomonas spp.), is a devastating disease. It can adversely affect the Capsicum annum productivity. Read More

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PVP-stabilized PtRu nanozymes with peroxidase-like activity and its application for colorimetric and fluorometric glucose detection.

Colloids Surf B Biointerfaces 2021 Apr 24;204:111783. Epub 2021 Apr 24.

Department of Bionano Engineering, Center for Bionano Intelligence Education and Research, Hanyang University, Ansan, 426-791, South Korea. Electronic address:

Nanozymes have significant advantages over natural enzymes. The intrinsic peroxidase-like activity of Pt-based nanomaterials can be enhanced by alloying with other transition metals, such as Ru, that have great catalytic activity. In this study, we used polyvinylpyrrolidone (PVP) to synthesize well-dispersed and homogeneous nanostructures. Read More

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Polyoxometalate-Mediated Vacancy-Engineered Cerium Oxide Nanoparticles Exhibiting Controlled Biological Enzyme-Mimicking Activities.

Inorg Chem 2021 May 3. Epub 2021 May 3.

Nanomaterials and Toxicology Lab, Division of Biological and Life Sciences, School of Arts and Sciences, Central Campus, Ahmedabad University, Navrangpura, Ahmedabad 380009, Gujarat, India.

The biological enzyme-mimetic activity of cerium oxide nanoparticles (CeNPs) is well known to scavenge the reactive oxygen and nitrogen species in cell culture and animal models, imparting protection from the deleterious effects of oxidative and nitrosative stress. The superoxide dismutase (SOD)- and catalase-mimicking activity of CeNPs is reported to be controlled by the oxidation state of the surface "Ce" ions, where a high ratio of Ce or Ce has been considered for the displayed SOD and catalase-like activity, respectively. However, the redox behavior of CeNPs can be controlled by certain ligands that could offer changes in their enzyme-mimetic properties. Read More

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Hollow POM@MOF-derived porous NiMo6@Co3O4 for superlative biothiol colorimetric detection.

Chemistry 2021 May 2. Epub 2021 May 2.

Jining University, Chemistry and Chemical Engineering, CHINA.

Developing highly active and sensitive peroxidase mimics for L -cysteine ( L -Cys) colorimetric detection is very important for biotechnology and medical diagnosis. Herein, polyoxometalate-doped porous Co 3 O 4 composite (NiMo 6 @Co 3 O 4 ) was designed and prepared for the first time. Compared with pure and commercial Co 3 O 4 , NiMo 6 @Co 3 O 4 (n) composites exhibit the enhanced peroxidase-mimicking activities and stabilities due to the strong synergistic effect between porous Co 3 O 4 and multi-electron NiMo 6 clusters. Read More

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Qiangji Jianli Decoction Alleviates Hydrogen Peroxide-Induced Mitochondrial Dysfunction via Regulating Mitochondrial Dynamics and Biogenesis in L6 Myoblasts.

Oxid Med Cell Longev 2021 13;2021:6660616. Epub 2021 Apr 13.

Institute of Pi-Wei, Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.

Oxidative stress can cause the excessive generation of reactive oxygen species (ROS) and has various adverse effects on muscular mitochondria. Qiangji Jianli decoction (QJJLD) is an effective traditional Chinese medicine (TCM) that is widely applied to improve muscle weakness, and it has active constituents that prevent mitochondrial dysfunction. To investigate the protective mechanism of QJJLD against hydrogen peroxide- (HO-) mediated mitochondrial dysfunction in L6 myoblasts. Read More

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Chemopreventive and Anticancer Property of Selenoproteins in Obese Breast Cancer.

Front Pharmacol 2021 16;12:618172. Epub 2021 Apr 16.

Center of Excellence in Molecular Biology and Regenerative Medicine, Department of Biochemistry, JSS Medical College, JSS Academy of Higher Education & Research, Mysore, India.

Obesity is a significant risk factor for various cancers including breast cancer resulting in an increased risk of recurrence as well as morbidity and mortality. Extensive studies on various pathways have been successful in establishing a biological relationship between obesity and breast cancer. The molecular classification of breast cancer includes five groups each having different responses to treatment. Read More

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NiCoS microflowers as peroxidase mimic: A multi-functional platform for colorimetric detection of glucose and evaluation of antioxidant behavior.

Talanta 2021 Aug 23;230:122337. Epub 2021 Mar 23.

Beijing Key Laboratory of Environmentally Harmful Chemical Analysis, College of Chemistry, Beijing University of Chemical Technology, Beijing, 100029, PR China. Electronic address:

The regular design of atomic composition of materials endows a diverse range of enzyme mimics types and increases a broader application prospect. In this study, we designed a nickel-cobalt mixed metal sulfide and demonstrated that the as-prepared NiCoS microflowers possessed intrinsic peroxidase-like activity. Nickel-cobalt sulfide (NiCoS) possessed high electron transfer capacity, which lead to good peroxidase-like activity. Read More

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Magnetic nanomaterials with unique nanozymes-like characteristics for colorimetric sensors: A review.

Talanta 2021 Aug 20;230:122299. Epub 2021 Mar 20.

Ningbo Municipal Center for Disease Control and Prevention, Ningbo, Zhejiang, 315010, China. Electronic address:

Colorimetric sensors for the rapid detection of numerous analytes have been widely applied in many fields such as biomedicine, food industry and environmental science due to their highly sensitive and selective response, easy operation and visual identification by naked eyes. In this review, the recent progress of the colorimetric sensors based on the magnetic nanomaterials with unique nanozymes-like catalytic activity (magnetic nanozyme) and their colorimetric sensing applications are presented. Emerging magnetic nanozyme-based colorimetric sensors, such as metal oxide/sulfides-based, metal-based, carbon-based, and aptamer-conjugated magnetic nanomaterials, offer many desirable features for target analytes detection. Read More

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