20,421 results match your criteria peripheral intravenous

Midline Catheters - a good alternative device?

Anaesth Crit Care Pain Med 2021 May 7:100885. Epub 2021 May 7.

Nursing and Midwifery Research Centre, Royal Brisbane and Women's Hospital, Queensland, Australia; Herston Infectious Diseases Institute (HEiDI), Metro North Hospitals and Health Service, Queensland, Australia; School of Nursing, Midwifery and Social Work, UQ Centre for Clinical Research, University of Queensland, Australia; School of Nursing and Midwifery, Menzies Health Institute Queensland, Griffith University, Australia.

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Successful early introduction of mepolizumab for peripheral neuropathy with a peripheral circulatory disorder in a patient with myeloperoxidase anti-neutrophil cytoplasmic antibody-negative eosinophilic granulomatosis with polyangiitis.

Mod Rheumatol Case Rep 2021 May 10:1-6. Epub 2021 May 10.

Division of Hematology and Rheumatology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan.

A 26-year-old woman presented with abdominal pain, diarrhoea, vomiting, fever, and progressive paralysis in the lower limbs. She had a history of bronchial asthma and experienced sinusitis, progressive peripheral neuropathy, polyarthritis, and leukocytosis with prominent eosinophilia. The patient was diagnosed with eosinophilic granulomatosis with polyangiitis (EGPA). Read More

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Intravenous Delayed Gadolinium-Enhanced MR Imaging of the Endolymphatic Space: A Methodological Comparative Study.

Front Neurol 2021 22;12:647296. Epub 2021 Apr 22.

Department of Neurology, University Hospital, Ludwig-Maximilians-Universität, Munich, Germany.

non-invasive verification of endolymphatic hydrops (ELH) by means of intravenous delayed gadolinium (Gd) enhanced magnetic resonance imaging of the inner ear (iMRI) is rapidly developing into a standard clinical tool to investigate peripheral vestibulo-cochlear syndromes. In this context, methodological comparative studies providing standardization and comparability between labs seem even more important, but so far very few are available. One hundred eight participants [75 patients with Meniere's disease (MD; 55. Read More

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Prevalence of Chemotherapy-Induced Peripheral Neuropathy in Multiple Myeloma Patients and its Impact on Quality of Life: A Single Center Cross-Sectional Study.

Front Pharmacol 2021 22;12:637593. Epub 2021 Apr 22.

INSERM U1107 NEURO-DOL, Université Clermont Auvergne, Clermont-Ferrand, France.

Bortezomib is a pivotal drug for the management of multiple myeloma. However, bortezomib is a neurotoxic anticancer drug responsible for chemotherapy-induced peripheral neuropathy (CIPN). CIPN is associated with psychological distress and a decrease of health-related quality of life (HRQoL), but little is known regarding bortezomib-related CIPN. Read More

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Impact of intravenous alteplase on sub-angiographic emboli in high-resolution diffusion-weighted imaging following successful thrombectomy.

Eur Radiol 2021 May 8. Epub 2021 May 8.

Department of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.

Objective: Thrombus microfragmentation causing peripheral emboli (PE) during mechanical thrombectomy (MT) may modulate treatment effects, even in cases with successful reperfusion. This study aims to investigate whether intravenous alteplase is of potential benefit in reducing PE after successful MT.

Methods: Patients from a prospective study treated at a tertiary care stroke center between 08/2017 and 12/2019 were analyzed. Read More

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Development and validation of LC/MS/MS method for Triciribine and its monophosphate metabolite in plasma and RBC: Application to mice pharmacokinetic studies.

J Chromatogr B Analyt Technol Biomed Life Sci 2021 Apr 20;1174:122714. Epub 2021 Apr 20.

Ayma Therapeutics Incorporated, USA. Electronic address:

Triciribine (TCN) is a tricyclic nucleoside analog of adenosine and an inhibitor of Akt kinase. Triciribine 5'-monophosphate (TCNP) is a water-soluble analog of Triciribine and has progressed to Phase I and II clinical trials in oncology. TCNP is also an endogenous anabolite of TCN similar to other nucleoside phosphates. Read More

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Investigation Of The Effects Of Propofol/Ketamine Versus Propofol/Fentanyl On Nausea-Vomiting Administered For Sedation In Children Undergoing Magnetic Resonance Imaging: A Prospective Randomized Double-Blinded Study.

Turk J Med Sci 2021 May 7. Epub 2021 May 7.

Purpose: In this study, we aimed to compare the effects of propofol-ketamine and propofol-fentanyl sedations on post-procedure nausea-vomiting in children undergoing magnetic resonance imaging (MRI).

Materials And Methods: This study included 100 pediatric patients (2-10 years old) who had propofol-ketamine and propofol-fentanyl for sedation to undergo MRI. The patients were divided into two groups, and sedation was performed through propofol-ketamine (Group K; n=50) or propofol-fentanyl (Group F; n=50). Read More

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Estimation of Clearance and Bioavailability of Therapeutic Monoclonal Antibodies from Only Subcutaneous Injection Data in Humans Based on Comprehensive Analysis of Clinical Data.

Clin Pharmacokinet 2021 May 6. Epub 2021 May 6.

Chugai Pharmaceutical Co., Ltd, 1-135 Komakado, Gotemba, Shizuoka, 412-8513, Japan.

Introduction: Theoretically, the separate estimation of clearance (CL) and bioavailability (F) requires both intravenous and extravascular injection data. This study investigated whether CL and subcutaneous F of therapeutic monoclonal antibodies (mAbs) in humans can be separately estimated from subcutaneous injection data only.

Methods: First, the geometric mean of linear pharmacokinetic parameters (CL, intercompartmental CL [Q], volume of distribution in the central compartment [V], and volume of distribution in the peripheral compartment [V]) after intravenous injection for mAbs in humans that have been reported in public data sources was estimated from 103 mAbs with linear pharmacokinetics and 44 mAbs with nonlinear pharmacokinetics. Read More

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Obturator nerve block does not provide analgesic benefits in total hip arthroplasty under multimodal analgesic regimen: a randomized controlled trial.

Reg Anesth Pain Med 2021 May 5. Epub 2021 May 5.

Department of Anesthesia, Clinique Medipole Garonne, Toulouse, Occitanie, France.

Background And Objectives: Although regional analgesia is considered an important component of optimal pain management, use of peripheral nerve blocks for total hip arthroplasty remains controversial. Since the obturator nerve innervates the anteromedial part of the joint capsule, we hypothesized that an obturator nerve block would decrease the opioid consumption after total hip arthroplasty.

Methods: In this single center, prospective, triple blinded study, we randomly allocated 60 patients undergoing total hip arthroplasty under opioid-sparing total intravenous general anesthesia to a preoperative obturator nerve block or a sham block (placebo group) using 20 mL of ropivacaine 0. Read More

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Cerebrospinal fluid and serum interleukins 6 and 8 during the acute and recovery phase in COVID-19 neuropathies patients.

J Med Virol 2021 May 5. Epub 2021 May 5.

Rehabilitation Unit, Maggiore City Hospital Department of Medicine, Surgery and Health Sciences, ASUGI, 34149, Trieste, Italy.

This case series describes three patients affected by SARS-CoV-2 who developed polyradiculoneuritis as a probable neurological complication of COVID-19. A diagnosis of Guillain Barré syndrome was made on the basis of clinical symptoms, cerebrospinal fluid analysis and electroneurography (ENG). In all of them therapeutic approach included the administration of intravenous immunoglobulin (0. Read More

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Monocentric study of 28 cases of chronic inflammatory demyelinating polyneuropathy: first Tunisian study.

Neurol Sci 2021 May 4. Epub 2021 May 4.

Department of Neurology, Military Hospital, Tunis, Tunisia.

Background: Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a rare affection of the peripheral nervous system. Its diagnostic criteria have evolved since 1975. The aim of our work is to study the epidemiological, clinical, and paraclinical aspects of CIDP. Read More

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CON: Peripheral intravenous access should always be secured before initiating food protein-induced enterocolitis syndrome oral food challenge.

Ann Allergy Asthma Immunol 2021 05;126(5):462-463

Division of Allergy and Immunology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:

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PRO: Peripheral intravenous access should always be secured before initiating food protein-induced enterocolitis syndrome oral food challenge.

Ann Allergy Asthma Immunol 2021 05;126(5):460-461

Pediatric Allergy Unit, Department of Child and Adolescent, University Hospitals of Geneva and University of Geneva, Geneva, Switzerland. Electronic address:

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Training Program for Ultrasound-Guided Intravenous Catheter Insertion.

Mil Med 2021 May 3. Epub 2021 May 3.

Naval Medical Center Camp Lejeune, Uniformed Services University, Camp Lejeune, NC 28547, USA.

Introduction: Ultrasound guidance is now widely available in military treatment facilities and civilian hospitals alike, both in the USA and in forward-deployed military environments. Technical mastery of ultrasound-guided peripheral intravenous (USGPIV) catheter insertion can be easily achieved through a short training course. Mastery can be achieved even when trainees have a limited medical background before course attendance. Read More

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A Need to Improve Peripheral Intravenous Access.

Maureen N Hood

Mil Med 2021 May 3. Epub 2021 May 3.

Department of Radiology & Radiological Sciences, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.

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Optimizing the Effectiveness of Short Peripheral Catheters.

Carrie Kollar

J Infus Nurs 2021 May-Jun 01;44(3):163-175

Mercy Washington Hospital, Washington, Missouri; Midwest Nursing and Vascular Services LLC, Salem, Illinois.

Hospitalized adult patients often require more than 1 short peripheral catheter (SPC) to complete the prescribed intravenous (IV) therapy attributed to catheter failure and the practice of routinely replacing SPCs. The purpose of this quality improvement project was to increase the number of SPCs that dwell for the complete duration of the IV therapy in hospitalized adult patients using a bundled approach. Implementation of an engineered securement device (ESD), education pertaining to modifiable risk factors, and changing the practice to removal on clinical indication were methods used to reduce the number of SPC insertions and catheter failures. Read More

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Disseminated coccidioidomycosis in a patient with juvenile idiopathic arthritis receiving infliximab.

Pediatr Rheumatol Online J 2021 May 1;19(1):63. Epub 2021 May 1.

Presbyterian Healthcare Services, New Mexico, Albuquerque, USA.

Background: Coccidioides immitis is a dimorphic fungus endemic to the arid climates of the Southwest United States, Mexico and parts of Central and South America. Human infection occurs through inhalation of spores with less than half of exposures progressing to a symptomatic state that primarily consists of pulmonary manifestations. Disseminated coccidioidomycosis is exceedingly rare, occurring in fewer than 1 % of symptomatic infections. Read More

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Mycobacterium tuberculosis causes a leaky blood-brain barrier and neuroinflammation in the prefrontal cortex and cerebellum regions of infected mice offspring.

Int J Dev Neurosci 2021 May 1. Epub 2021 May 1.

Department of Human Physiology, School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of Kwazulu Natal, Durban, South Africa.

The maternal system's exposure to pathogens influences foetal brain development through the influx of maternal cytokines and activation of the foetal immune status to a persistent inflammatory state characterised by glia cell activation. Neuroinflammation influences the blood-brain barrier's (BBB) permeability allowing peripheral immune cell trafficking into the brain. Mycobacterium tuberculosis (Mtb) is a pathogen that causes Tuberculosis (TB), a global pandemic responsible for health and economic burdens. Read More

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Effectiveness of supplemental oral calcium drink in preventing citrate-related adverse effects in peripheral blood progenitor cell collection.

Transfus Apher Sci 2021 Apr 24:103147. Epub 2021 Apr 24.

Department of Hematology and Oncology, Okayama University Hospital, Okayama, Japan.

Peripheral blood progenitor cells (PBPCs) are a predominant graft source in allogeneic hematopoietic cell transplantation. Citrate-induced hypocalcemia remains the most frequent side effect of PBPC apheresis. Although the method for preventing severe adverse events is established, more efficient prophylaxis is required so that volunteer donors can donate PBPCs without pain and anxiety. Read More

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Predictive factors for anxiety during blood sampling and insertion of peripheral intravenous catheters in paediatric patients in Spain.

J Pediatr Nurs 2021 Apr 28. Epub 2021 Apr 28.

UPNA (University of Navarra), Pamplona, Navarra, Spain. Electronic address:

Introduction: Invasive procedures for diagnosis purposes such as venepuncture and peripheral venous catheter insertion are painful procedures that cause great stress for paediatric patients. The objective of this study is to find out the factors that have an impact on the level of anxiety experienced by children undertaken these procedures.

Design And Methods: Prospective study, 359 children between 2 and 15 years old were included, treated in a tertiary reference hospital in the region of Navarra (Spain). Read More

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The analgesic efficacy of iPACK after knee surgery: A systematic review and meta-analysis with trial sequential analysis.

J Clin Anesth 2021 Apr 28;72:110305. Epub 2021 Apr 28.

Consultant, Department of Anaesthesia, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom; Honourary Senior Lecturer, King's College London, London, United Kingdom.

Study Objective: The novel infiltration between the popliteal artery and the capsule of the posterior knee (iPACK) has been described to relieve posterior knee pain after knee surgery. The study objective is to determine whether iPACK provides analgesia after knee surgery when compared with a control group.

Design: Systematic review, meta-analysis and trial sequential analysis. Read More

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The physiological basis of insulin therapy in people with diabetes mellitus.

Diabetes Res Clin Pract 2021 Apr 27:108839. Epub 2021 Apr 27.

Section of Endocrinology and Metabolism, Department of Medicine and Surgery, Perugia University School of Medicine, Perugia, Italy.

Insulin therapy has been in use now for 100 years, but only recently insulin replacement has been based on physiology. The pancreas secretes insulin at a variable rate finely regulated by arterial glucose sensing in the portal blood to insulinize preferentially the liver. In the fasting state, insulin is secreted at a low rate to modulate hepatic glucose output. Read More

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A simulation study of high-flow versus normal-flow three-way stopcock for rapid fluid administration in emergency situations: A randomised crossover design.

Aust Crit Care 2021 Apr 26. Epub 2021 Apr 26.

Department of Acute Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo Bunkyo-ku, Tokyo 113-8655, Japan. Electronic address:

Background: Initial fluid resuscitation is presumed to be important for treating shock in the resuscitation phase. However, little is known how quickly and easily a physician could perform a rapid infusion with a syringe.

Objectives: We hypothesised that using a high-flow three-way stopcock (HTS) makes initial fluid resuscitation faster and easier than using a normal-flow three-way stopcock (NTS). Read More

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Ultrasound-guided peripheral intravenous access in chronic kidney disease patients.

J Vasc Access 2021 Apr 30:11297298211012212. Epub 2021 Apr 30.

Department of Emergency Medicine, MetroHealth Medical Center, Cleveland, OH, USA.

Objective: Ultrasound-guided peripheral intravenous (USPIV) catheters are being placed in emergency department (ED) patients with increasing frequency. USPIV catheters have been shown to improve the success rates of cannulation. It is unknown what the long-term effect of USPIV placement will be on fistula creation in chronic kidney disease (CKD) patients considering these ultrasound-guided peripheral lines often target the same deeper vessels used for fistulas. Read More

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Non-Tumorigenic Pluripotent Reparative Muse Cells Provide a New Therapeutic Approach for Neurologic Diseases.

Cells 2021 Apr 20;10(4). Epub 2021 Apr 20.

Department of Stem Cell Biology and Histology, School of Medicine, Tohoku University, Sendai 980-8575, Japan.

Muse cells are non-tumorigenic endogenous reparative pluripotent cells with high therapeutic potential. They are identified as cells positive for the pluripotent surface marker SSEA-3 in the bone marrow, peripheral blood, and connective tissue. Muse cells also express other pluripotent stem cell markers, are able to differentiate into cells representative of all three germ layers, self-renew from a single cell, and are stress tolerant. Read More

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Type II Collagen-Specific B Cells Induce Immune Tolerance in Th1-Skewed, Th2-Skewed, and Arthritis-Prone Strains of Mice.

Cells 2021 Apr 12;10(4). Epub 2021 Apr 12.

Department of Integrative Biology, College of Arts and Sciences, University of South Florida, St. Petersburg, FL 33701, USA.

Antigen-specific regulatory T cells play key immune suppressive roles in autoimmune disease models and regulate the peripheral tolerance achieved via anterior chamber-associated immune deviation (ACAID). Articular cartilage has type II collagen (CII), which is a potent autoantigen protein in arthritis. There has not been much research on the clinical importance of CII-associated diseases. Read More

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Effects of a Clinically Indicated Peripheral Intravenous Replacement on Indwelling Time and Complications of Peripheral Intravenous Catheters in Pediatric Patients: A Randomized Controlled Trial.

Int J Environ Res Public Health 2021 Apr 5;18(7). Epub 2021 Apr 5.

Department of Nursing, Chang Gung Memorial Hospital at Linkou, Taoyuan 333, Taiwan.

Peripheral intravenous catheters (PVCs) are common treatment modalities for pediatric patients, and may cause infection, infiltration, occlusion, and phlebitis. The purpose of this study was to evaluate the effect of a clinically indicated peripheral intravenous replacement (CIPIR) on PVC indwelling time and complication rates in pediatric patients. This study used a randomized, pre- and post-repeated measures design. Read More

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The impact of IPACK combined with adductor canal block under ultrasound guidance on early motor function after total knee arthroplasty.

Braz J Anesthesiol 2021 Apr 26. Epub 2021 Apr 26.

The Affiliated Hospital of Qingdao University, Department of Anesthesiology, Qingdao, China.

Background: This study aimed to evaluate the impact of Infiltration between the Popliteal Artery and Capsule of the posterior Knee (IPACK) combined with an adductor canal block under the guidance of ultrasound on early motor function after Total Knee Arthroplasty (TKA).

Methods: A sample of 60 cases who were scheduled for elective unilateral TKA were divided into two groups using random number table method: a group with IPACK combined with an adductor canal block (I group, n = 30), and a group with femoral nerve block combined with superior popliteal sciatic nerve block (FS group, n = 30). Before anesthesia induction was completed, the patients in I group received an ultrasound-guided adductor canal block with 15 mL of 0. Read More

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Investigation of cardiorespiratory effects of the selective 5-HT4 agonist BIMU-8 in etorphine-immobilised goats (Capra aegagrus hircus) in a randomized, blinded and controlled trial.

Vet Rec 2021 Feb 19:e76. Epub 2021 Feb 19.

Centre for Veterinary Wildlife Studies and Department of Paraclinical Sciences, University of Pretoria, Pretoria, South Africa.

Background: Opioid-induced respiratory compromise remains a significant challenge in etorphine-immobilised wildlife. Serotonergic agonists offer a potential avenue for preventing or treating opioid-induced respiratory compromise. We therefore aimed to determine whether the selective 5-hydroxytryptamine receptor 4 (5-HT4) agonist, BIMU-8, reverses opioid-induced respiratory compromise in etorphine-immobilised goats. Read More

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February 2021

Efficacy and safety of Chinese patent medicine (Kang-ai injection) as an adjuvant in the treatment of patients with hepatocellular carcinoma: a meta-analysis.

Pharm Biol 2021 Dec;59(1):472-483

Dispensing Room for Intravenous Transfusion, Weifang People's Hospital, Weifang, China.

Context: Kang-ai injection (KAI) is an authorized herbal medicine used in cancer treatment. However, its clinical efficacy in hepatocellular carcinoma (HCC) has not been investigated thoroughly.

Objective: To systematically evaluate the efficacy and safety of KAI in patients with HCC. Read More

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December 2021