Photodiagnosis Photodyn Ther 2021 Jul 21:102451. Epub 2021 Jul 21.
Department of Diagnostic and Surgery, Periodontics Division, São Paulo State University - UNESP, Dentistry School of Araçatuba, Araçatuba, SP, Brazil.. Electronic address:
Background: The aim of this study was to compare, through clinical and microbiological analysis, the use of multiple applications of aPDT as an adjuvant therapy to non-surgical periodontal treatment of stage III and IV grade C periodontitis in type 2 diabetic (DM2) patients.
Methods: Thirty-four patients with non-compensated DM2 and periodontitis were randomly divided into two groups: SRP Group (n=17): scaling and root planning (SRP); and SRP+aPDT Group (n=17): SRP followed by 3 consecutive aPDT applications, immediately, 48 and 96 hours after in pockets with probing depth (PD) ≥5mm. In SRP+aPDT, after 1 minute of irrigation with methylene blue (10mg/ml), the sites were irradiated with a 660 nm diode laser for 50 seconds (157 J/cm, 4. Read More