638 results match your criteria perianal wound

A Retrospective Study of Touchless Spray for Pediatric Perineal Burns Treatment.

J Burn Care Res 2021 Jul 26. Epub 2021 Jul 26.

Department of Surgery, Division of Pediatric Surgery, Children's Hospital of Michigan/Wayne State University, Detroit, MI, USA.

Background: Silver-based topical treatments have seen widespread use for the management of burns due to silver's antimicrobial activity. Recent studies suggest silver nanoparticles could negatively impact healing time due to their toxic effect on keratinocytes and fibroblasts at higher concentrations [1, 2]. Zinc oxide antimicrobial activity has been demonstrated in vitro [3, 4] and results from animal studies are promising for burn management [5]. Read More

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Unique hybrid double apposing flap in a Z-plasty technique to reconstruct major perianal defect resulting from chondyloma acuminatum resection - Case report.

Adnan G Gelidan

Int J Surg Case Rep 2021 Jun 21;83:106002. Epub 2021 May 21.

Department of Surgery, King Khalid University Hospital, King Saud University, Saudi Arabia.

Perianal area is anatomically challenging location to reconstruct after wide extensive local excision especially when preserving the anus anatomy anal sphincter continence is a requirement. That is the case in many benign locally aggressive conditions, due to high risk of suture line disruption, wound dehiscence, and wound infection. Many surgical options like primary closure, loco reginal flaps, distant or pedicled flaps, or even free flaps are available for such reconstruction. Read More

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Prognostic factors associated with unhealed perineal wounds post-proctectomy for perianal Crohn's disease: a two-centre study.

Colorectal Dis 2021 May 21. Epub 2021 May 21.

St Mark's Hospital, Harrow, UK.

Aim: The aim of this work was to determine the factors associated with poor wound healing in patients with perianal Crohn's disease (pCD) who had undergone proctectomy in the era of biologic therapies.

Method: Case record review was performed on 103 patients with pCD who underwent proctectomy at St Mark's Hospital, Harrow and the Western General Hospital, Edinburgh between 2005 and 2017. Healing rates at 6 and 12 months post-proctectomy were considered; univariate analysis was performed. Read More

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Longitudinal profiling of the burn patient cutaneous and gastrointestinal microbiota: a pilot study.

Sci Rep 2021 May 21;11(1):10667. Epub 2021 May 21.

Department of Pathology and Laboratory Medicine, University of California Davis, 4400 V St., Sacramento, CA, 95817, USA.

Sepsis is a leading cause of morbidity and mortality in patients that have sustained a severe burn injury. Early detection and treatment of infections improves outcomes and understanding changes in the host microbiome following injury and during treatment may aid in burn care. The loss of functional barriers, systemic inflammation, and commensal community perturbations all contribute to a burn patient's increased risk of infection. Read More

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Adjunctive Hyperbaric Oxygen Therapy in Refractory Crohn's Disease: An Observational Study.

Gastroenterol Res Pract 2021 26;2021:6628142. Epub 2021 Apr 26.

Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil.

Background And Aims: Patients may experience complications of Crohn's disease (CD) even when treated with optimal medical therapy strategies. Previous data have shown the efficacy of hyperbaric oxygen therapy (HBOT) in the management of complicated CD. However, there is no consensus regarding the optimal number of sessions or duration of treatment regimens. Read More

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Temporary Diverting End-Colostomy in Critically Ill Children with Severe Perianal Wound Infection.

Adv Skin Wound Care 2021 Jun;34(6):322-326

At the Ankara University School of Medicine, Turkey, Emrah Gün, MD, is Fellow, Department of Pediatric Critical Care Medicine; Tanil Kendirli, MD, is Professor, Department of Pediatric Critical Care Medicine; Edin Botan, MD, is Fellow, Department of Pediatric Critical Care Medicine; Halil Özdemir, MD, is Associate Professor, Department of Pediatric Infectious Disease; Ergin Çiftçi, MD, is Professor, Department of Pediatric Infectious Disease; Kübra Konca, MD, is Fellow, Department of Pediatric Infectious Disease; Meltem Koloğlu, MD, is Professor, Department of Pediatric Surgery; Gülnur Göllü, MD, is Associate Professor, Department of Pediatric Surgery; Özlem Selvi Can, MD, is Associate Professor, Department of Pediatric Anesthesia; Ercan Tutar, MD, is Professor, Department of Pediatric Cardiology; Ahmet Rüçhan Akar, MD, is Professor, Department of Cardiovascular Surgery, Heart Center, Cebeci Hospitals; and Erdal İnce, MD, is Professor, Department of Pediatric Infectious Disease. Acknowledgments: The authors wish to thank all the pediatric ICU nursing staff for all their efforts and support for our critically ill pediatric patients. The authors have disclosed no financial relationships related to this article. Submitted June 24, 2020; accepted in revised form September 25, 2020.

Abstract: Broad and deep perianal wounds are challenging in both adult and pediatric ICUs. These wounds, if contaminated with gastrointestinal flora, can cause invasive sepsis and death, and recovery can be prolonged. Controlling the source of infection without diverting stool from the perianal region is complicated. Read More

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A Giant Sacrococcygeal Teratoma in an Adult Male: A Case Report.

Cureus 2021 Mar 29;13(3):e14181. Epub 2021 Mar 29.

Surgery, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.

Sacrococcygeal teratoma (SCT) in adults is very rare with only a few cases reported in the literature. Its presentation in the adult is asymptomatic to a slow-growing cystic tumor with a 1-2% chance for malignant transformation and may attain a huge size causing pressure effect on pelvic and intra-abdominal organs. It can present unusually as a perianal abscess which needs to be evaluated radiologically. Read More

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[Reconstruction of oncological defects of the perianal region].

Chirurg 2021 Apr 27. Epub 2021 Apr 27.

Plastisch- und Handchirurgische Klinik und Labor für Tissue Engineering und Regenerative Medizin, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg FAU, Krankenhausstraße 12, 91054, Erlangen, Deutschland.

In addition to the progressive development of surgical oncological techniques for malignant tumors of the rectum, anal canal and vulva, reconstructive procedures after oncological interventions in the perianal region represent a cornerstone in the postoperative quality of life of patients. Modern treatment modalities for rectal cancer with neoadjuvant chemoradiotherapy increase the survival rate and simultaneously reduce the risk of local recurrence to 5-10%, especially by cylindrical extralevatory extirpation of the rectum. The price for increased surgical radicality and improved oncological safety is the acceptance of larger tissue defects. Read More

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Fournier's gangrene as a rare complication in patient with uncontrolled type 2 diabetes treated with surgical debridement: A case report and literature review.

Int J Surg Case Rep 2021 Feb 30;79:462-465. Epub 2021 Jan 30.

Department of General Surgery and Medical-Surgical Specialties, Policlinico - Vittorio Emanuele Hospital, University of Catania, Italy.

Introduction: Fournier's gangrene is a potentially fatal emergency condition, supported by an infection of perineal and perianal region, characterized by necrotizing fasciitis with a rapid spread to fascial planes. FG, usually due to compromised host, may be sustained by many microbial pathogens.

Case Report: A 66-year-old man, with a history of uncontrolled type 2 diabetes, obesity with BMI 38, chronic kidney failure and chronic heart failure, was admitted to the Emergency Department with a large area of necrosis involving the perineal and perianal regions. Read More

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February 2021

[Healing of severe morbus Crohn-related pyoderma gangrenosum after colectomy].

Ugeskr Laeger 2021 03;183(11)

This case report describes a patient with colonic Crohn's disease and perianal disease. The patient experienced extensive and severe pyoderma gangrenosum after colectomy. Steroids and anti-inflammatory medication had no effect on pyoderma or the persistent perianal and rectal disease. Read More

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Is sterile exposure in perianal procedures necessary? A single-institution experience and results from a national survey.

Tech Coloproctol 2021 05 4;25(5):539-548. Epub 2021 Mar 4.

Department of Surgery, Groene Hart Hospital, Gouda, The Netherlands.

Background: Surgical site infections (SSI) are the most common postoperative complications. To minimize the risk of SSI, there is a strict asepsis policy in the operating theatre. The aim of this study was to evaluate the risk and cost-saving benefit of performing perianal surgery in a non-sterile setting. Read More

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Challenging Treatment of a Female Patient with Extensive Fournier's Gangrene - Case Report.

Prague Med Rep 2021 ;122(1):39-44

University Clinic of Abdominal Surgery, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, Skopje, North Macedonia.

Fournier's gangrene (FG) is a necrotizing fasciitis of the genital, perianal and perineal regions, caused by multiple anaerobic/aerobic infection. It is a rare but very serious condition with multiple long-term complications and high mortality rate. Early diagnosis and multidisciplinary approach in treatment of complicated cases of FG are crucial to the successful outcome. Read More

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Efficacy and safety of ligation of intersphincteric fistula tract in the treatment of anal fistula: A protocol for systematic review and meta-analysis.

Medicine (Baltimore) 2021 Jan;100(4):e23700

Air Force Hospital of Eastern Theater Command, Nanjing, Jiangsu province, China.

Background: Anal fistula is characterized with perianal cellulitis, anorectal pain, smelly or bloody drainage of pus, and difficulty in controlling bowel movements. Ligation of intersphincteric fistula tract (LIFT) technique is a recently developed approach against anal fistula, and it could alleviate the pain of the patient, with little postoperative trauma, which can greatly shorten the wound healing time and hospitalization stay. We conduct the meta-analysis and systematic review to systematically evaluate the clinical efficacy and safety of LIFT in the treatment of anal fistula. Read More

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January 2021

Fournier's gangrene with dapagliflozin in a rural hospital: a case report.

BMJ Case Rep 2021 Feb 1;14(2). Epub 2021 Feb 1.

Clinical Pharmacy Department, Winchester District Memorial Hospital, Winchester, Ontario, Canada.

Sodium-glucose cotransporter 2 (SGLT2) inhibitors, which are used for treatment of type 2 diabetes, are associated with risk of urogenital infections. FDA issued a black box warning about multiple case reports of Fournier's gangrene (FG) observed in patients taking SGLT2 inhibitors. FG is a type of necrotising fasciitis that occurs in the anogenital area. Read More

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February 2021

Comparative study between intersphinecteric ligation of perianal fistula versus conventional fistulotomy with or without seton in the treatment of perianal fistula: A prospective randomized controlled trial.

Ann Med Surg (Lond) 2021 Jan 18;61:180-184. Epub 2020 Dec 18.

General Surgery, Faculty of Medicine, Menoufia University, Egypt.

Background: Fistula-in-ano is one of the most common benign anal conditions in daily surgical practice.The goals in the treatment of an anal fistula are to eradicate sepsis and to eliminate the primary fistula opening, any associated tracts, and any secondary openings without a change in continence. Conventional fistulotomy (lay open of the fistula tract) is a commonly used procedure and is still relied on by the majority of surgeons as the gold standard for the treatment of perianal fistula. Read More

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January 2021

Survival and Operative Outcomes After Salvage Surgery for Recurrent or Persistent Anal Cancer.

Ann Coloproctol 2020 Dec 31;36(6):361-373. Epub 2020 Dec 31.

Department of Colon and Rectal Surgery, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Anal squamous cell carcinoma (SCC) is a relatively rare cancer comprising less than 2.5% of all gastrointestinal malignancies. The standard treatment for anal SCC is primary chemoradiation therapy which can result in complete regression. Read More

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December 2020


Arq Bras Cir Dig 2021 15;33(3):e1545. Epub 2021 Jan 15.

Alimentary Tract Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Khouzestan, Iran.

Background: Oblique type of anastomosis. Several types of complications including constipation, fecal soiling, perianal excoriation, were reported among different types of surgery for Hirschsprung's disease.

Aim: To compare circular and oblique anastomoses following Soave's procedure for the treatment of Hirschsprung's disease. Read More

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February 2021

Needle aspiration treatment vs. incision of acute simple perianal abscess: randomized controlled study.

Int J Colorectal Dis 2021 Mar 15;36(3):581-588. Epub 2021 Jan 15.

Research Unit for Surgery, Odense University Hospital, J.B. Winsløws Vej 4, 5000, Odense C, Denmark.

Purpose: Needle aspiration of an acute simple perianal abscess may be an alternative to conventional incision drainage with potential advantages in wound healing, functional outcome, and quality of life. The aim and objectives of the study are to compare the outcome of needle aspiration and postoperative antibiotics with that of conventional surgical incision drainage of acute perianal abscess. The primary outcome was abscess recurrence. Read More

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Management of large and surrounding tissue infiltrative anal fistula cancer: Two case reports.

Int J Surg Case Rep 2020 21;77:643-646. Epub 2020 Nov 21.

Department of Surgery, Yonsei University Wonju College of Medicine, Wonju, South Korea. Electronic address:

Introduction: Adenocarcinoma originating from chronic perianal fistulas is a rare disease. Due to the lack of evidence of this malignancy, no definitive diagnostic and treatment guidelines have been established. We present two cases of anal fistula cancer and discuss the diagnostic and treatment strategies. Read More

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November 2020

The Role of Autologous Flap Reconstruction in Patients with Crohn's Disease Undergoing Abdominoperineal Resection.

Dis Colon Rectum 2021 04;64(4):429-437

Section of Plastic Surgery, Department of Surgery, University of Michigan, Ann Arbor, Michigan.

Background: Patients with symptomatic Crohn's disease who undergo abdominoperineal resection can experience impaired postoperative wound healing. This results in significant morbidity, burdensome dressing changes, and increased postoperative pain. When abdominoperineal resection is performed for oncological reasons, autologous flap reconstruction is occasionally performed to optimize wound healing and reconstruction outcomes. Read More

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A Case of Large Perianal Mucinous Adenocarcinoma Arising from Recurrent Abscess and Complex Fistulae.

Case Rep Surg 2020 18;2020:1798543. Epub 2020 Dec 18.

Plastic and Reconstructive Surgery Unit, Department of Surgery, UKM Medical Centre, Kuala Lumpur, Malaysia.

Mucinous adenocarcinoma of the perianal region is an oncologic rarity posing a diagnostic and therapeutic dilemma for treating oncologists. This is due to the low number of reported cases, compounded by the lack of definitive therapeutic guidelines. It accounts for 2% to 3% of all gastrointestinal malignancies and is historically known to arise from chronic anal fistulas and ischiorectal or perianal abscesses. Read More

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December 2020

[Consensus of Chinese experts on the diagnosis and treatment of anal fistula (2020)].


Zhonghua Wei Chang Wai Ke Za Zhi 2020 Dec;23(12):1123-1130

Anal fistula is one of the most common diseases in colorectal and anal surgery. Most of them are formed after the abscess of perianal space reptures. Due to the complexity and diversity of pathological changes, the clinical efficacy of some patients is not optimistic, and there may even be serious surgical complications, including delayed healing of anal fistula or varying degrees of fecal incontinence, which significantly affect the quality of life of patients and even lead to disability. Read More

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December 2020

Iatrogenic allergic contact dermatitis in the (peri)anal and genital area.

Contact Dermatitis 2021 Jun 10;84(6):431-438. Epub 2021 Jan 10.

Department of Dermatology, Contact Allergy Unit, University Hospitals Leuven, Leuven, Belgium.

Background: Allergic contact dermatitis (ACD) from topical medication often occurs in occluded areas, for example, with wound treatment, but also in certain body locations, such as the anogenital area.

Objectives: To investigate the demographics and specific lesion location of patients with ACD from topical drugs applied onto the (peri)anal/genital area, and to identify the respective causal topical pharmaceutical products and ingredients involved.

Methods: From January 2000 to December 10, 2018, 532 patients were tested with the baseline series, sometimes with additional series, and the topical medication used along with the ingredients. Read More

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Endoscopic vacuum therapy with instillation (iEVT) - a novel endoscopic concept for colorectal anastomotic leak and perianal complications.

Wideochir Inne Tech Maloinwazyjne 2020 Dec 24;15(4):560-566. Epub 2020 Feb 24.

Department of General, Endocrinological and Gastroenterological Oncology Surgery, Poznan University of Medical Sciences, Poznan, Poland.

Introduction: Anastomotic leaks remain the most fearful complications.

Aim: We present a novel endoscopic salvage therapy known as endoscopic vacuum therapy with instillation (iEVT) as a combination of standard endoscopic vacuum therapy (EVT) and negative pressure wound therapy with instillation (iNPWT).

Material And Methods: A case series of 6 consecutive patients treated with iEVT is presented. Read More

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December 2020

Perianorectal abscesses and fistula due to ingested jujube pit in infant: Two case reports.

World J Clin Cases 2020 Oct;8(20):4930-4937

Department of General Surgery, Children's Hospital of Shanghai, Shanghai Jiao Tong University, Shanghai 200333, China.

Background: About 90% of perianal infection is caused by cryptoglandular infection. Only a few cases of peritonitis or intra-abdominal abscesses secondary to perforation of the digestive tract by an ingested foreign body have been reported. The most common sites of impaction and perforation include the appendix, cecum and the terminal ileum. Read More

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October 2020

Survey to define informational needs of patients undergoing surgery for Crohn's anal fistula.

Colorectal Dis 2021 Jan 4;23(1):132-144. Epub 2020 Dec 4.

General Surgery, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.

Aim: There are many surgical treatments used in Crohn's anal fistula, although none is perfect. Decisions about surgery in this condition may be preference sensitive. The aim of this study was to identify what information patients would like in order to make treatment decisions and to explore experiences of making decisions in this setting. Read More

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January 2021

Anal Metastasis from Lung Cancer: Report of a Case and Systematic Review of the Literature.

Chirurgia (Bucur) 2020 Sept-Oct;115(5):681-689

Lung cancer is the most frequent cancer, accounting for over 2 million new cases per year worldwide. In Romania, the cancers with the highest incidence are lung cancer for men and breast cancer for women. Cancer-related deaths follow the same pattern. Read More

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December 2020

A retrospective case series of Fournier's gangrene: necrotizing fasciitis in perineum and perianal region.

BMC Surg 2020 Oct 30;20(1):259. Epub 2020 Oct 30.

General Surgery, Jilin University Second Hospital, No 218 ZiQiang Street, Changchun, 130000, China.

Background: To describe the clinical characteristics and management for Fournier's gangrene. Experience summary and literature references are provided for future treatment improvement.

Methods: We retrospectively reviewed the cases diagnosed with Fournier's gangrene in our department from June 2016 to June 2019. Read More

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October 2020

An Aggressive Tumoral Metastasis to Groin Arising from Perianal Squamous Cell Carcinoma: Management of a Unique Case.

Indian J Surg Oncol 2020 Sep 4;11(Suppl 1):90-92. Epub 2020 May 4.

Department of General Surgery, Adiyaman University Education and Research Hospital, Adiyaman, Turkey.

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September 2020

The Prevalence of Incontinence-Associated Dermatitis in Hospitalized Patients in China: A Systematic Review and Meta-Analysis.

Adv Skin Wound Care 2020 Oct;33(10):1-7

Min Wei, MS, is Enterostomal Therapist, Wound Care Center, Nanjing Drum Tower Hospital, Jiangsu, China. Dongliang Yang, MS, is Associate Professor, Cangzhou Medical College, Hebei. Ling Wu, BS, is Enterostomal Therapist, Wound Care Center; Wenyue Chen, BS, is Head Nurse, Department of Orthopedics; Yan Chen, BS, is Director, Nursing Department; and Qiaomei Fu, BS, is Head Nurse, Surgery Branch, Nanjing Drum Tower Hospital. The authors have disclosed no financial relationships related to this article. Submitted August 13, 2019; accepted in revised form February 20, 2020.

Objective: To determine the prevalence and characteristics of incontinence-associated dermatitis (IAD) among hospitalized Chinese patients.

Data Sources: Authors searched Chinese (China National Knowledge Infrastructure, Wanfang Data, VIP Data, Chinese Biomedicine) and English (PubMed, Web of Science) electronic databases for articles published from 1987 through February 2019.

Study Selection: The preliminary search identified 558 studies. Read More

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October 2020