110,406 results match your criteria performance measures


Automated detection of hippocampal sclerosis: Comparison of a composite MRI-based index with conventional MRI measures.

Epilepsy Res 2021 Apr 9;174:106638. Epub 2021 Apr 9.

Department of Radiology, Sanbo Brain Hospital, Capital Medical University, China. Electronic address:

Purpose: This study aims to compare the performance of an MRI-based composite index (HSI) with conventional MRI-based measures in hippocampal sclerosis (HS) detection and postoperative outcome estimation.

Methods: Seventy-two temporal lobe epilepsy (TLE) patients with pathologically confirmed HS and fifteen TLE patients without HS were included retrospectively. The T1-weighted and FLAIR images of these patients were processed with AccuBrain to quantify the hippocampal volume (HV) and the hippocampal FLAIR signal. Read More

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EMS blood collection from patients with acute chest pain reduces emergency department length of stay.

Am J Emerg Med 2021 Apr 26;47:248-252. Epub 2021 Apr 26.

Department of Emergency Medicine, Wake Forest School of Medicine, USA.

Background: Expediting the measurement of serum troponin by leveraging EMS blood collection could reduce the diagnostic time for patients with acute chest pain and help address Emergency Department (ED) overcrowding. However, this practice has not been examined among an ED chest pain patient population in the United States.

Methods: A prospective observational cohort study of adults with non-traumatic chest pain without ST-segment elevation myocardial infarction was conducted in three EMS agencies between 12/2016-4/2018. Read More

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Validation of the Bath CRPS Body Perception Disturbance Scale.

J Pain 2021 May 5. Epub 2021 May 5.

Department of Psychology, University of Bath, Claverton Down, Bath, BA2 7AY, United Kingdom; Centre for Pain Research, University of Bath, Claverton Down, Bath, BA2 7AY, United Kingdom.

The Bath Complex Regional Pain Syndrome Body Perception Disturbance Scale ("B-CRPS-BPDS") measures alterations in body perception. We assessed its internal consistency, known group validity, construct validity, and associations with demographic and clinical characteristics. We also evaluated changes in, and baseline predictors of B-CRPS-BPDS scores at follow-up. Read More

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Single implant overdenture reinforced with a metallic framework: A 2-year clinical follow-up.

Spec Care Dentist 2021 May 8. Epub 2021 May 8.

Department of Prosthodontics and Periodontology, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil.

Introduction: To prevent single-implant overdenture (SIO) fracture, the inclusion of a framework in the overdenture has been suggested. However, no investigations verified their benefits.

Objective: To evaluate prosthetic maintenance events, patient satisfaction, and mastication of SIO reinforced by metallic framework users. Read More

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Correlates of memory and executive function in mid-aged and older adults in the CLSA: A minority stress approach.

J Gerontol B Psychol Sci Soc Sci 2021 May 8. Epub 2021 May 8.

School of Epidemiology and Public Health, University of Ottawa, Ottawa, Ontario, Canada.

Objectives: Maintaining cognitive function is an important component of healthy aging. There is increasing recognition that extraneous factors expedite the typical cognitive aging process. Risk factors for cognitive decline cluster around inequalities and disproportionally affect minority and vulnerable groups. Read More

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Functional Link Convolutional Neural Network for the Classification of Diabetes Mellitus.

Int J Numer Method Biomed Eng 2021 May 8:e3496. Epub 2021 May 8.

Dept. of Computer Science and Engineering, Bennett University, Noida, Uttar Pradesh, India.

Diabetes is a faction of metabolic ailments distinguished by hyperglycemia which is the consequence of a defect ,in the action of insulin, insulin secretion, or both and producing various abnormalities in the human body. In recent years, the utilization of intelligent systems has been expanded in disease classification and numerous researches have been proposed. In this research article, a variant of Convolutional Neural Network i. Read More

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Cognitive and Electrophysiological Correlates of Working Memory Impairments in Neurofibromatosis Type 1.

J Autism Dev Disord 2021 May 8. Epub 2021 May 8.

Division of Neuroscience & Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Room 3.310 Jean McFarlane Building, Oxford Road, Manchester, M13 9WL , UK.

Neurofibromatosis 1 (NF1) is a single gene disorder associated with working Memory (WM) impairments. The aim of this study was to investigate P300 event-related potential (ERP) associated with WM in NF1. Sixteen adolescents with NF1 were compared with controls on measures of WM and EEG was recorded during a WM nback task. Read More

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The cognitive and behavioral effects of D-amphetamine and nicotine sensitization in adult zebrafish.

Psychopharmacology (Berl) 2021 May 8. Epub 2021 May 8.

School of Pharmacy and Biomedical Science, University of Portsmouth, St Michael's Building, White Swan Road, Portsmouth, PO1 2DT, UK.

Background: Zebrafish are growing in use as a model for understanding drug dependence and addiction. Sensitization paradigms have been a useful tool in identifying mechanisms involved in drug-induced behavioral and neurological changes, but in zebrafish have tended to focus on locomotor, rather than cognitive, endpoints.

Methods: Here, we used a novel method, the FMP Y-maze, which measures continuous performance through a series of repeated binary choices (L vs R), to establish a model for assessing parameters associated with psychostimulant-induced behavioral and cognitive sensitization in adult zebrafish. Read More

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Conflating marginal and conditional treatment effects: Comments on "Assessing the performance of population adjustment methods for anchored indirect comparisons: A simulation study".

Stat Med 2021 May;40(11):2753-2758

Department of Statistical Science, University College London, London, UK.

In this commentary, we highlight the importance of: (1) carefully considering and clarifying whether a marginal or conditional treatment effect is of interest in a population-adjusted indirect treatment comparison; and (2) developing distinct methodologies for estimating the different measures of effect. The appropriateness of each methodology depends on the preferred target of inference. Read More

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Comparison of 2D and 3D quiescent-interval slice-selective non-contrast MR angiography in patients with peripheral artery disease.

MAGMA 2021 May 8. Epub 2021 May 8.

Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

Objective: To evaluate the potential clinical benefit of the superior spatial resolution of 3D prototype thin-slab stack-of-stars (tsSOS) quiescent-interval slice-selective (QISS) MRA over standard 2D-QISS MRA for the detection peripheral artery disease (PAD), using computed tomography angiography (CTA) as reference.

Materials And Methods: Twenty-three patients (70 ± 8 years, 18 men) with PAD who had previously undergone run-off CTA were prospectively enrolled. Patients underwent non-contrast MRA using 2D-QISS and tsSOS-QISS at 1. Read More

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Quality of care and risk of incident atrial fibrillation in patients with newly-diagnosed heart failure: A nationwide cohort study.

Eur Heart J Qual Care Clin Outcomes 2021 May 7. Epub 2021 May 7.

Danish Center for Clinical Health Services Research, Aalborg University, Aalborg, Denmark.

Aims: Incident atrial fibrillation (AF) is an adverse prognostic indicator in heart failure (HF); identifying modifiable targets may be relevant to reduce the incidence and morbidity of AF. Therefore, we examined the association between quality of HF care and risk of AF.

Methods And Results: Using the Danish Heart Failure Registry, we conducted a nationwide registry-based cohort study of all incident HF patients diagnosed between 2008 and 2018 and without history of AF. Read More

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JUUL 'new technology' pods exhibit greater electrical power and nicotine output than previous devices.

Tob Control 2021 May 7. Epub 2021 May 7.

Mechanical Engineering, American University of Beirut, Beirut, Lebanon

In 2019, JUUL Labs began marketing in the European Union 'new technology' pods that incorporated a new wick that it claimed provided 'more satisfaction'. In this study, we compared design and materials of construction, electrical characteristics, liquid composition and nicotine and carbonyl emissions of new technology JUUL pods to their predecessors. Consistent with manufacturer's claims, we found that the new pods incorporated a different wicking material. Read More

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Exploring the actionability of healthcare performance indicators for quality of care: a qualitative analysis of the literature, expert opinion and user experience.

BMJ Qual Saf 2021 May 7. Epub 2021 May 7.

Department of Public and Occupational Health, Academic Medical Centre, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, The Netherlands.

Background: This study explores the meaning of actionable healthcare performance indicators for quality of care-related decisions. To do so, we analyse the constructs of and across healthcare systems and in practice based on the literature, expert opinion and user experience.

Methods: A multiphase qualitative study was undertaken. Read More

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Reference values and validation of the 1-minute sit-to-stand test in healthy 5-16-year-old youth: a cross-sectional study.

BMJ Open 2021 May 7;11(5):e049143. Epub 2021 May 7.

Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland

Objectives: It is essential to have simple, reliable and valid tests to measure children's functional capacity in schools or medical practice. The 1-minute sit-to-stand (STS) test is a quick fitness test requiring little equipment or space that is increasingly used in both healthy populations and those with chronic disease. We aimed to provide age-specific and sex-specific reference values of STS test in healthy children and adolescents and to evaluate its short-term reliability and construct validity. Read More

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Automated control of oxygen titration in preterm infants on non-invasive respiratory support.

Arch Dis Child Fetal Neonatal Ed 2021 May 7. Epub 2021 May 7.

School of Engineering, University of Tasmania College of Sciences and Engineering, Hobart, Tasmania, Australia.

Objective: To evaluate the performance of a rapidly responsive adaptive algorithm (VDL1.1) for automated oxygen control in preterm infants with respiratory insufficiency.

Design: Interventional cross-over study of a 24-hour period of automated oxygen control compared with aggregated data from two flanking periods of manual control (12 hours each). Read More

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Longitudinal MRI brain volume changes over one year in children with mucopolysaccharidosis types IIIA and IIIB.

Mol Genet Metab 2021 Apr 27. Epub 2021 Apr 27.

Center for Gene Therapy, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Division of Neurology, Nationwide Children's Hospital, Department of Pediatrics, The Ohio State University, Department of Neurology, Columbus, OH, United States of America. Electronic address:

Objective: To quantify changes in segmented brain volumes over 12 months in children with mucopolysaccharidosis types IIIA and IIIB (MPS IIIA and IIIB).

Methods: In order to establish suitable outcome measures for clinical trials, twenty-five children greater than 2 years of age were enrolled in a prospective natural history study of MPS IIIA and IIIB at Nationwide Children's Hospital. Data from sedated non-contrast brain 3 T MRIs and neuropsychological measures were reviewed from the baseline visit and at 12-month follow-up. Read More

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Risk-adjusted rates between hospitals for adverse outcomes of very-low-birth-weight infants.

J Formos Med Assoc 2021 May 4. Epub 2021 May 4.

Department of Pediatrics, National Taiwan University Hospital Hsinchu Branch, Taiwan.

Background/purpose: To analyze the amount of variation in these risk-adjusted adverse outcomes corresponding to the care of premature births. In addition, hospitals were ranked according to their unadjusted and adjusted rates, and we assessed the degree of concordance between these rankings. Finally, the correlations of hospital-adjusted adverse outcomes were also tested. Read More

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Heat recovery steam generator (HRSG) three-element drum level control utilizing Fractional order PID and fuzzy controllers.

ISA Trans 2021 Apr 29. Epub 2021 Apr 29.

Machine Intelligence Research Labs (MIR Labs), Scientific Network for Innovation and Research Excellence, Auburn, WA, United States. Electronic address:

Shrink and swell is a phenomenon that causes transient variability in water level once boiler load variation occurs. The leading cause of the swell effect is the steam demand changes and the actual arrangement of steam generating tubes in the boiler. Steam bubbles beneath HRSG drum water make the level control very difficult, particularly with significant disturbances in the input heat to HRSG. Read More

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School performance and behavioral functioning in children after intrauterine transfusions for hemolytic disease of the fetus and newborn.

Early Hum Dev 2021 May 4;157:105381. Epub 2021 May 4.

Department of Medical Psychology, Leiden University Medical Center, the Netherlands.

Aim: To investigate the school performance and behavioral difficulties in children with hemolytic disease of the fetus and newborn (HDFN) treated with intrauterine transfusion (IUT) compared to Dutch norm data.

Study Design: Cros-sectional cohort study.

Subjects: Children who received one or multiple IUTs for severe Rh- or K (Kell)-mediated HDFN between January 2008 and January 2015 at the LUMC. Read More

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Ortho_Sim_Loc: Essential protein prediction using orthology and priority-based similarity approach.

Comput Biol Chem 2021 Apr 28;92:107503. Epub 2021 Apr 28.

Department of Computer Science & Engineering, Netaji Subhash Engineering College, Techno City, Panchpota, Garia, Kolkata, 700152, India. Electronic address:

Proteins are the essential macro-molecules of living organism. But all proteins cannot be considered as essential in different relevant studies. Essentiality of a protein is thus computed by computation methods rather than biological experiments which in turn save both time and effort. Read More

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6-Month Respiratory Outcomes and Exercise Capacity of COVID-19 Acute Respiratory Failure Patients Treated With CPAP.

Intern Med J 2021 May 7. Epub 2021 May 7.

Unit of General Medicine and Advanced Care, IRCCS San Raffaele Scientific Institute, Mali.

Background: COVID-19 long-term sequelae are ill-defined since only few studies have explored the long-term consequences of this disease so far.

Objective: to evaluate the 6-month respiratory outcomes and exercise capacity of COVID-19 acute respiratory failure (ARF) patients treated with continuous positive airway pressure (CPAP) during the first wave of the ongoing COVID-19 pandemic.

Design: retrospective observational study. Read More

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Direct health system costs for systemic lupus erythematosus patients in Alberta, Canada.

PLoS One 2021 7;16(5):e0251409. Epub 2021 May 7.

Analytics and Performance Reporting Branch, Alberta Health, Edmonton, Canada.

Systemic lupus Erythematosus (SLE) is a chronic multi-system autoimmune disease that can affect a person's physical, mental, and social life. It imposes a substantial economic burden up on patients, carers, healthcare systems, and wider society. This is the first study to examine the direct health care costs of SLE in Alberta using real-world data. Read More

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Handgrip Strength as a Reflection of General Muscle Strength in Chronic Obstructive Pulmonary Disease.

COPD 2021 May 7:1-12. Epub 2021 May 7.

Laboratory of Research in Respiratory Physiotherapy (LFIP), Department of Physiotherapy, State University of Londrina (UEL), Londrina, Brazil.

Muscle dysfunction is one of the main features in individuals with chronic obstructive pulmonary disease (COPD). Handgrip strength (HS) has been used as a representation of general muscle strength in various populations, and a few studies found correlation between HS and other measures of upper and lower limbs' muscle strength in the general population, although this was not yet studied in depth in COPD. The aims of this study were to verify if HS is cross-sectionally well correlated with upper and lower limbs' muscle strength in individuals with COPD, and to identify a new cutoff for handgrip weakness in this population. Read More

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Short-term research projects in cognitive neuroscience for undergraduate students: a contingency plan to maintain quality teaching during COVID-19 pandemic.

Adv Physiol Educ 2021 Jun;45(2):376-383

Cognitive Neuroscience Laboratory, Department of Physiology, Monash Biomedicine Discovery Institute, Monash University, Victoria, Australia.

The Corona Virus Disease 19 (COVID-19) pandemic has imposed serious restrictions for academic institutions to maintain their research and teaching practical subjects. Universities have implemented adaptive measures to maintain educational activities and achieve the learning objectives for undergraduate and postgraduate students by shifting to online teaching and learning. Although such approaches have enabled delivering the theoretical content of courses during the pandemic, universities have faced serious difficulties in running practicals with actual research experiments and teaching hand-on skills because such activities potentially override the required safety guidelines. Read More

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The Effects of a Novel Quarterly Cardiopulmonary Resuscitation Training Program on Hospital Basic Life Support Providers' Cardiopulmonary Resuscitation Skill Performance.

J Nurses Prof Dev 2021 May-Jun 01;37(3):131-137

This is a retrospective descriptive study of a novel cardiopulmonary resuscitation (CPR) training program. Using quarterly, brief CPR training at a skills station, hospital basic life support providers who failed to meet CPR performance measures during the first quarter quickly improved on the skills necessary to meet CPR measures. Those meeting CPR measures during the first quarter maintained that performance over time. Read More

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How to learn the International Standards to document remaining Autonomic Function after Spinal Cord Injury (ISAFSCI) content: Self-study through booklet is not enough.

J Spinal Cord Med 2021 May 7:1-8. Epub 2021 May 7.

Clinic for Spinal Cord Injuries, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

To investigate the baseline knowledge of autonomic functions and specifically the International Standards to document remaining Autonomic Function after Spinal Cord Injury (ISAFSCI) among medical students and to present the effective methods in learning of the ISAFSCI Interventional training session A tertiary hospital. 37 medical students Before training, a self-rating questionnaire including 24 concepts extracted from the ISAFSCI was administrated to the students. Then students were divided into two groups. Read More

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Validation of the Munich Actimetry Sleep Detection Algorithm for estimating sleep-wake patterns from activity recordings.

J Sleep Res 2021 May 7:e13371. Epub 2021 May 7.

Institute of Medical Psychology, Ludwig Maximilian University Munich, Munich, Germany.

Periods of sleep and wakefulness can be estimated from wrist-locomotor activity recordings via algorithms that identify periods of relative activity and inactivity. Here, we evaluated the performance of our Munich Actimetry Sleep Detection Algorithm. The Munich Actimetry Sleep Detection Algorithm uses a moving 24-h threshold and correlation procedure estimating relatively consolidated periods of sleep and wake. Read More

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Neuroimaging genetic associations between , brain structure, and reading skills.

J Clin Exp Neuropsychol 2021 May 7:1-14. Epub 2021 May 7.

Department of Psychology, University of Houston, Houston, TX, USA.

Specific reading disability (SRD) is defined by genetic and neural risk factors that are not fully understood. The current study used imaging genetics methodology to investigate relationships between , brain structure, and reading. , located on SRD risk locus DYX1, is involved in axon guidance, synapse formation, and dendrite development. Read More

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Deep Learning based Multi-modal Computing with Feature Disentanglement for MRI Image Synthesis.

Med Phys 2021 May 7. Epub 2021 May 7.

School of Computer Science, Sichuan University, China.

Purpose: Different Magnetic resonance imaging (MRI) modalities of the same anatomical structure are required to present different pathological information from the physical level for diagnostic needs. However, it is often difficult to obtain full-sequence MRI images of patients owing to limitations such as time consumption and high cost. The purpose of this work is to develop an algorithm for target MRI sequences prediction with high accuracy, and provide more information for clinical diagnosis. Read More

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Memory binding and theta EEG during middle childhood.

Dev Psychobiol 2021 May 6. Epub 2021 May 6.

Department of Psychology, Virginia Tech, Blacksburg, Virginia, USA.

The ability to bind together the contextual details associated with an event undergoes dramatic improvement during childhood. However, few studies have examined the neural correlates of memory binding encoding and retrieval during middle childhood. We examined age-related encoding and retrieval differences using continuous electroencephalogram (EEG) measures in a sample of 6- and 8-year-olds. Read More

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