474,454 results match your criteria people 2020

Impact of scaling up SARS-CoV-2 vaccination on COVID-19 hospitalizations in Spain.

Int J Infect Dis 2021 Sep 15. Epub 2021 Sep 15.

UNIR Health Sciences School & Medical Center, Madrid, Spain. Electronic address:

Background: The advent of SARS-CoV-2 vaccines has been associated with a significant decline in COVID-19 hospitalizations and deaths. However, little is known about the benefits experienced by different population groups and/or using distinct vaccines.

Methods: We analyzed the Spanish public registry for associations between calendar vaccination scale up and incidence of COVID-19 hospitalizations by age, gender and vaccine modality. Read More

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September 2021

Safety and efficacy of oral levosimendan in people with amyotrophic lateral sclerosis (the REFALS study): a randomised, double-blind, placebo-controlled phase 3 trial.

Lancet Neurol 2021 Oct;20(10):821-831

Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, and Department of Neurology, King's College Hospital, King's College London, London, UK.

Background: There is an urgent unmet need for new therapies in amyotrophic lateral sclerosis. In a clinical study with healthy volunteers, levosimendan, a calcium sensitiser, was shown to improve neuromechanical efficiency and contractile function of the human diaphragm. We aimed to evaluate the safety and efficacy of oral levosimendan in people with amyotrophic lateral sclerosis, with a focus on respiratory function. Read More

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October 2021

Safety and immunogenicity of an inactivated COVID-19 vaccine, BBIBP-CorV, in people younger than 18 years: a randomised, double-blind, controlled, phase 1/2 trial.

Lancet Infect Dis 2021 Sep 15. Epub 2021 Sep 15.

Beijing Institute of Biological Products, Beijing, China.

Background: Although SARS-CoV-2 infection often causes milder symptoms in children and adolescents, young people might still play a key part in SARS-CoV-2 transmission. An efficacious vaccine for children and adolescents could therefore assist pandemic control. For further evaluation of the inactivated COVID-19 vaccine candidate BBIBP-CorV, we assessed the safety and immunogenicity of BBIBP-CorV in participants aged 3-17 years. Read More

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September 2021

Which factors increase informal care hours and societal costs among caregivers of people with dementia? A systematic review of Resource Utilization in Dementia (RUD).

Health Econ Rev 2021 Sep 18;11(1):37. Epub 2021 Sep 18.

Centre for Elderly and Nursing Home Medicine, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.

Background: Nearly 19 million people across OECD countries are living with dementia, and millions of family caregivers are affected by the disease. The costs of informal care are estimated to represent 40-75% of the total dementia cost exceeding formal care time and medical costs.

Objective: To conduct a systematic review to evaluate the methodological quality and factors associated with high informal care hours per month that increase societal costs, and to identify what type of interventions may alleviate the entire burden of informal and formal caregiving. Read More

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September 2021

Smartphone-based virtual agents and insomnia management: A proof-of-concept study for new methods of autonomous screening and management of insomnia symptoms in the general population.

J Sleep Res 2021 Sep 18:e13489. Epub 2021 Sep 18.

Université de Bordeaux, SANPSY USR 3413, Bordeaux, France.

Insomnia is the most frequent sleep disorder, and the COVID-19 crisis has massively increased its prevalence in the population, due to psychosocial stress or direct viral contamination. KANOPEE_2 is a smartphone-based application that provides interactions with a virtual agent to autonomously screen and alleviate insomnia symptoms through an intervention programme giving personalized advices regarding sleep hygiene, relaxation techniques and stimulus-control. In this proof-of-concept study, we tested the effects of KANOPEE_2 among users from all over the country (France) who downloaded the app between 1 June and 26 October 2020 (to focus on effects after the end of COVID-19 confinement). Read More

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September 2021

[Decline in life expectancy in Madrid's districts in 2020: its correlation with social determinants].

Gac Sanit 2021 Sep 14. Epub 2021 Sep 14.

Madrid Salud, Departamento de Evaluación y Calidad, Ayuntamiento de Madrid, Madrid, España.

Objective: Estimating the decrease in life expectancy (LE) of the population of Madrid and its districts and its relationship with socioeconomic variables in the first year of the COVID-19 pandemic.

Method: Death records were obtained from the Municipal Register of inhabitants (Municipal Statistics Service). Based on Chiang II method, life expectancy at birth and at 65 years of age (LEB and LE65) were calculated, as well as their 95% confidence intervals both for men and women and their gross, net and minimum falls for each district in 2020 over 2019, their correlation with some socioeconomic variables distribution and the existence of multiple linear regression explicative models. Read More

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September 2021

Post-traumatic stress disorder among persons with HIV who engage in heavy alcohol consumption in southwestern Uganda.

BMC Psychiatry 2021 Sep 18;21(1):457. Epub 2021 Sep 18.

Department of Medicine, University of California, San Francisco, CA, USA.

Background: We aimed to describe the prevalence of PTSD symptoms and its associated factors in persons living with HIV (PLWH) in Uganda who engage in heavy alcohol use.

Methods: We analyzed baseline data from the Drinkers Intervention to Prevent Tuberculosis study which enrolls PLWH with latent tuberculosis who engage in heavy alcohol consumption. Using the primary care Post Traumatic Stress Disorder (PTSD) screening scale from the DSM-5 (PC-PTSD-5), probable PTSD was defined as reporting ≥3 of 5 assessed symptoms. Read More

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September 2021

Heavy episodic drinking and HIV disclosure by HIV treatment status among People with HIV in IeDEA Cameroon.

Int J Drug Policy 2021 Sep 14;98:103431. Epub 2021 Sep 14.

University of North Carolina at Chapel Hill, United States.

Background: Heavy alcohol use is common among people with HIV (PWH), leading to sub-optimal HIV care outcomes. Yet, heavy episodic drinking (HED) is not routinely addressed within most HIV clinics in sub-Saharan Africa. HIV disclosure may provide social support, potentially reducing HED to cope with HIV. Read More

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September 2021

Transcending global health dogma: an Indigenous perspective.

Lancet Glob Health 2021 Oct;9(10):e1357-e1358

Institute of Psychology, University of São Paulo, São Paulo, Brazil.

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October 2021

Long-Acting Injectable Antipsychotic Medication Plus Customized Adherence Enhancement in Poor Adherence Patients With Bipolar Disorder.

Prim Care Companion CNS Disord 2021 Sep 16;23(5). Epub 2021 Sep 16.

Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, University Hospitals Cleveland Medical Center, Cleveland, Ohio.

People with bipolar disorder (BD) often have difficulty with medication adherence. This pilot trial combined a behavioral customized adherence enhancement (CAE) approach with long-acting injectable (LAI) antipsychotic medication and assessed effects on adherence, BD symptoms, and functional status.

This 6-month prospective, uncontrolled trial of the intervention (CAE with LAI) in 30 poorly adherent individuals with BD assessed adherence using the Tablets Routine Questionnaire (TRQ) and symptoms using the Brief Psychiatric Rating Scale (BPRS), Young Mania Rating Scale (YMRS), Hamilton Depression Rating Scale (HDRS), and Clinical Global Impressions (CGI). Read More

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September 2021

The impact of integrated care in community-based substance use treatment in Brazil: A longitudinal study.

Health Soc Care Community 2021 Sep 17. Epub 2021 Sep 17.

Nursing School of Lisbon, Lisbon, Portugal.

Integrated care (outpatient-inpatient) plays a vital function in community care for people with drug use problems. Its recent and innovative treatment model is representing a challenge for the deinstitutionalisation process. The purpose of this study was to assess the impact of integrated care using biopsychosocial indicators. Read More

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September 2021

Performance of COVID-19 associated symptoms and temperature checking as a screening tool for SARS-CoV-2 infection.

PLoS One 2021 17;16(9):e0257450. Epub 2021 Sep 17.

Kumasi Centre for Collaborative Research, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Introduction: Coronavirus disease-19 (COVID-19), which started in late December, 2019, has spread to affect 216 countries and territories around the world. Globally, the number of cases of SARS-CoV-2 infection has been growing exponentially. There is pressure on countries to flatten the curves and break transmission. Read More

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September 2021

The effect of unobserved preferences and race on vaccination hesitancy for COVID-19 vaccines: implications for health disparities.

J Manag Care Spec Pharm 2021 Sep;27(9-a Suppl):S4-S13

Larner College of Medicine, University of Vermont, Burlington.

Reducing the extra burden COVID-19 has on people already facing disparities is among the main national priorities for the COVID-19 vaccine rollout. Early reports from states releasing vaccination data by race show that White residents are being vaccinated at significantly higher rates than Black residents. Public health efforts are being targeted to address vaccine hesitancy among Black and other minority populations. Read More

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September 2021

Comparison of Characteristics of Deaths From Drug Overdose Before vs During the COVID-19 Pandemic in Rhode Island.

JAMA Netw Open 2021 Sep 1;4(9):e2125538. Epub 2021 Sep 1.

Department of Epidemiology, Brown University School of Public Health, Providence, Rhode Island.

Importance: The rate of deaths from overdose has increased during the COVID-19 pandemic, and recent US overdose mortality rates have been markedly high. However, scant data are available on the causes of this increase or subpopulations at elevated risk.

Objective: To evaluate the rates and characteristics of deaths from drug overdose before vs during the COVID-19 pandemic. Read More

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September 2021

Assessing prevalence of SARS-CoV-2 infection in children by antibody detection in saliva: A prospective, longitudinal study protocol (Coro-Buddy).

JMIR Res Protoc 2021 Aug 10. Epub 2021 Aug 10.

Institut für Tropenmedizin, Universitätsklinikum Tübingen, Tübingen, Germany, Wilhelmstraße 27, Tübingen, DE.

Background: The world is confronting with the COVID-19 pandemic for more than one year. Severe disease is more often found in elderly people, whereas most of young children and adolescents show mild symptoms or even remain asymptomatic, so that infection might be undiagnosed. Therefore, only limited epidemiological data on SARS-CoV-2 infection in children and young adults are available. Read More

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Assessment of household food waste management during the COVID-19 pandemic in Serbia: a cross-sectional online survey.

Environ Sci Pollut Res Int 2021 Sep 16. Epub 2021 Sep 16.

Faculty of Applied Management, Economics and Finance, University Business Academy in Novi Sad, Belgrade, Serbia.

The Serbian government has taken several measures to prevent the spread of COVID-19. These measures may have led to a disruption of daily life and affected food-related behaviors. This paper investigates the state of food waste management in Serbia and COVID-19's direct effect on consumer awareness, food consumption, and food waste behaviors. Read More

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September 2021

Experiential QI Activity for Residents to Improve Women's Preventive Services.

PRiMER 2021 27;5:25. Epub 2021 Jul 27.

Department of Family and Community Medicine, University of Texas Southwestern Medical Center, Dallas, TX.

Introduction: The Accreditation Council for Graduate Medical Education (ACGME) requires family medicine residents to complete a quality improvement (QI) project. There is a need for more QI training activities to be shared to meet this requirement. Our objective was to describe an activity for residents to improve women's preventive health services in an underserved clinic. Read More

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Household Coping Strategies During the COVID-19 Pandemic in Chile.

Front Sociol 2021 31;6:728095. Epub 2021 Aug 31.

Department of Sociology, Pontificia Universidad Católica de Chile, Santiago, Chile.

Chile was severely hit by the COVID-19 pandemic. The implementation of social distancing measures strongly affected the Chilean economy: the unemployment rate grew rapidly as well as the proportion of population temporarily excluded from the labour force. This article analyses the strategies deployed by Chilean households to cope with the impact of the pandemic at the intersection with household structure and its socio-economics characteristics. Read More

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Anxious and Angry: Emotional Responses to the COVID-19 Threat.

Front Psychol 2021 31;12:676116. Epub 2021 Aug 31.

Department of Psychology, University of Amsterdam, Amsterdam, Netherlands.

The current coronavirus disease 2019 (COVID-19) pandemic elicits a vast amount of anxiety. In the current study, we investigated how anxiety related to COVID-19 is associated with support for and compliance with governmental hygiene measures, and how these are influenced by populist attitudes, anger at the government, and conspiracy mentalities. We conducted an online survey in April 2020 in four different countries (Germany, the Netherlands, Spain, and the UK; = 2,031) using a cross-sectional design. Read More

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Real-time quantitation of thyroidal radioiodine uptake in thyroid disease with monitoring by a collar detection device.

Sci Rep 2021 Sep 16;11(1):18479. Epub 2021 Sep 16.

Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Johns Hopkins University School of Medicine, 1830 E. Monument St./Ste. 333, Baltimore, MD, 21287, USA.

Radioactive iodine (RAI) is safe and effective in most patients with hyperthyroidism but not all individuals are cured by the first dose, and most develop post-RAI hypothyroidism. Postoperative RAI therapy for remnant ablation is successful in 80-90% of thyroid cancer patients and sometimes induces remission of nonresectable cervical and/or distant metastatic disease but the effective tumor dose is usually not precisely known and must be moderated to avoid short- and long-term adverse effects on other tissues. The Collar Therapy Indicator (COTI) is a radiation detection device embedded in a cloth collar secured around the patient's neck and connected to a recording and data transmission box. Read More

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September 2021

[National Health control in ports and airports of the Balearic Islands. SARS-CoV-2 Containment (March-June 2020).]

Rev Esp Salud Publica 2021 Sep 17;95. Epub 2021 Sep 17.

Dirección General de Salud Pública y Participación. Islas Baleares. España.

During the state of alert declared in the national territory in March 2020 due to the health crisis caused by SARS-CoV-2, the free movement of the population was restricted in order to prevent the spread of the virus. In the Balearic Islands, access by air and sea was limited and, in addition, health controls were established at the entry points of the islands aimed to detect people with COVID-19. The health check is understood as a Public Health surveillance procedure through which all persons authorised to travel at that time were tested. Read More

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September 2021

Impact of COVID-19 on Ophthalmic Outpatient Services in An Eye Care Center in Southern Nigeria.

Niger J Clin Pract 2021 Sep;24(9):1338-1342

Department of Ophthalmology, University of Benin, Benin City, Nigeria.

Background: Coronavirus disease-2019 (COVID-19) is a communicable disease and a global pandemic affecting different parts of the world including Nigeria. Measures to curb the spread of the causative virus included a nationwide lockdown.

Aim: The aim of this study was to assess the impact of COVID-19 on ophthalmic outpatient services in an eye care center in Nigeria. Read More

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September 2021

Cancer symptom experience and help-seeking behaviour during the COVID-19 pandemic in the UK: a cross-sectional population survey.

BMJ Open 2021 Sep 16;11(9):e053095. Epub 2021 Sep 16.

PRIME Centre Wales, Division of Population Medicine, School of Medicine, Cardiff University, Cardiff, UK.

Objectives: To understand self-reported potential cancer symptom help-seeking behaviours and attitudes during the first 6 months (March-August 2020) of the UK COVID-19 pandemic.

Design: UK population-based survey conducted during August and September 2020. Correlates of help-seeking behaviour were modelled using logistic regression in participants reporting potential cancer symptoms during the previous 6 months. Read More

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September 2021

Quick-Wee versus bladder stimulation to collect midstream urine from precontinent infants under 1 year of age: a study protocol for a randomised controlled trial (ES.Stimquick.U).

BMJ Open 2021 Sep 16;11(9):e046324. Epub 2021 Sep 16.

Service des Urgences Pédiatriques, Hôpitaux Pédiatriques de Nice CHU-LENVAL, Nice, France.

Introduction: Urinary tract infections occur in around 1%-4% of boys and 3%-8% of girls under 2 years old. Diagnosis is difficult because of non-specific symptoms and the risk of urine analysis contamination depending on the sampling method used for precontinent infants. The American Academy of Pediatrics recommend transurethral catheterisation and suprapubic aspiration because of a low contamination rate but these techniques are invasive. Read More

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September 2021

Seroprevalence of IgM and IgG Antibodies against SARS-CoV-2 in Asymptomatic People in Wuhan: Data from a General Hospital Near South China Seafood Wholesale Market during March to April in 2020.

Biomed Environ Sci 2021 Sep;34(9):743-749

National Institute of Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing 100050, China.

The aim of this study was to estimate the seroprevalence of immunoglobulin M (IgM) and G (IgG) antibodies against SARS-CoV-2 in asymptomatic people in Wuhan. This was a cross-sectional study, which enrolled 18,712 asymptomatic participants from 154 work units in Wuhan. Pearson Chi-square test, -test, and Mann-Whitney test were used to compare the standardized seroprevalence of IgG and IgM for age and gender between different groups. Read More

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September 2021

Feasibility and effectiveness of daily temperature screening to detect COVID-19 in a prospective cohort at a large public university.

BMC Public Health 2021 Sep 16;21(1):1693. Epub 2021 Sep 16.

School of Public Health, Division of Epidemiology and Biostatistics, University of California, Berkeley, 2121 Berkeley Way # 5302, Berkeley, CA, 94720, USA.

Background: Many persons with active SARS-CoV-2 infection experience mild or no symptoms, presenting barriers to COVID-19 prevention. Regular temperature screening is nonetheless used in some settings, including university campuses, to reduce transmission potential. We evaluated the potential impact of this strategy using a prospective university-affiliated cohort. Read More

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September 2021

Community interventions for improving adult mental health: mapping local policy and practice in England.

BMC Public Health 2021 Sep 16;21(1):1691. Epub 2021 Sep 16.

Department of Sport and Exercise Sciences, Durham University, 42 Old Elvet, Durham, DH1 3HN, UK.

Background: Public mental health (PMH) aims to improve wellbeing and prevent poor mental health at the population level. It is a global challenge and a UK priority area for action. Communities play an important role in the provision of PMH interventions. Read More

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September 2021

Incorporating Aboriginal women's voices in improving care and reducing risk for women with diabetes in pregnancy - A phenomenological study.

BMC Pregnancy Childbirth 2021 Sep 16;21(1):624. Epub 2021 Sep 16.

Menzies School of Health Research, Charles Darwin University, NT, Darwin, Australia.

Background: There is a high burden of gestational diabetes (GDM) and type 2 diabetes in pregnancy for Aboriginal and Torres Strait Islander women. Postpartum diabetes programs have the potential to prevent recurrent GDM and improve management of type 2 diabetes. However, data on such programs are limited, particularly in the Indigenous context. Read More

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September 2021

Effect of Strict Lockdown on Pediatric Surgical Services and Residency Programme during COVID-19 Pandemic.

J Coll Physicians Surg Pak 2021 Jan;31(1):S75-S78

Department of Pediatric Surgery, National Institute of Child Health, Jinnah Sindh Medical University, Karachi, Pakistan.

Objective: To document the measures adopted during the COVID-19 pandemic strict lockdown on pediatric surgical services and residents' training at a tertiary care hospital.

Study Design: Cross-sectional descriptive study.

Place And Duration Of Study: Department of Pediatric Surgery, National Institute of Child Health, Jinnah Sindh Medical University, Karachi, from April 2020 to June 2020. Read More

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January 2021