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A scanning dynamic collimator for spot-scanning proton minibeam production.

Sci Rep 2021 Sep 15;11(1):18321. Epub 2021 Sep 15.

Institut Curie, Université PSL, CNRS UMR3347, Inserm U1021, Signalisation Radiobiologie et Cancer, 91400, Orsay, France.

In proton minibeam radiation therapy, proton minibeams are typically produced by modulating a uniform field using a multislit collimator. Multislit collimators produce minibeams of fixed length and width, and a new collimator has to be manufactured each time a new minibeam array is required, limiting its flexibility. In this work, we propose a scanning dynamic collimator for the generation of proton minibeams arrays. Read More

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September 2021

Influence of eye movement on lens dose and optic nerve target coverage during craniospinal irradiation.

Clin Transl Radiat Oncol 2021 Nov 29;31:28-33. Epub 2021 Aug 29.

Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, the Netherlands.

Purpose: Optic nerves are part of the craniospinal irradiation (CSI) target volume. Modern radiotherapy techniques achieve highly conformal target doses while avoiding organs-at-risk such as the lens. The magnitude of eye movement and its influence on CSI target- and avoidance volumes are unclear. Read More

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November 2021

Pediatric patients accessing Accident and Emergency Department (A&E) for non-urgent treatment: Why do parents take their children to the A&E?

Int Emerg Nurs 2021 Sep 11;58:101053. Epub 2021 Sep 11.

Academic Department of Pediatrics, Bambino Gesù Children's Hospital, IRCCS, Piazza Sant'Onofrio 4, 00165 Rome, Italy. Electronic address:

Introduction: About 20-30% of children access the Pediatric Accident and Emergency Department (A&E) for non-urgent health care that should normally follow other health care paths. This study aimed to investigate why parents take their children to the A&E for non-urgent visits rather than using primary care services.

Methods: A one-year cross-sectional study was conducted in a large pediatric A&E in Italy. Read More

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September 2021

Technical Note: Clinical modeling and validation of breast tissue expander metallic ports in a commercial treatment planning system for proton therapy.

Med Phys 2021 Sep 14. Epub 2021 Sep 14.

Department of Radiation Oncology, Mayo Clinic, 5881 East Mayo Blvd, Phoenix, AZ, 85054.

Purpose: To validate breast tissue expander metallic port (MP) models in a commercial treatment planning system (TPS) in proton pencil beam scanning (PBS) treatments for breast cancer patients with breast tissue expanders.

Methods And Materials: Three types of MPs taken out of a Mentor CPX4, a Natrelle 133, and a PMT Integra breast tissue expanders and a 650cc saline filled Mentor CPX4 expander were placed on top of acrylic slabs, and scanned using a Siemens Somatom Definition AS Open RT CT scanner. Structure templates for each of the MPs were designed within Eclipse TPS. Read More

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September 2021

EXPRESS: Semantic Feedback Processing Mechanism of the Enactment Effect: Evidence from ERPs.

Q J Exp Psychol (Hove) 2021 Sep 10:17470218211047944. Epub 2021 Sep 10.

Northeast Normal University, Changchun, China 47821.

The enactment effect refers to a phenomenon in which the memory performance for action phrases is enhanced by performing the described action (e.g., sharpen a pencil) compared to simply reading the action phrase. Read More

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September 2021

Standardization of the psychometric hepatic encephalopathy score in a French population.

PLoS One 2021 10;16(9):e0257136. Epub 2021 Sep 10.

Brain Liver Pitié-Salpêtrière (BLIPS) Study Group, Groupe Hospitalier Pitié-Salpêtrière, AP-HP, Sorbonne Université, Paris, France.

The Psychometric Hepatic Encephalopathy Score (PHES) has previously been standardized in thirteen countries on three continents, confirming its status of gold standard test to detect minimal hepatic encephalopathy (MHE). In the meantime, performance has also been shown to vary with variables such as age, education, and barely sex. The present study aimed at standardizing the PHES in a French population. Read More

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September 2021

Matrix Pencil Method for Vital Sign Detection from Signals Acquired by Microwave Sensors.

Sensors (Basel) 2021 Aug 26;21(17). Epub 2021 Aug 26.

Electronic Measurements and Signal Processing Group, Technische Universität Ilmenau, 98693 Ilmenau, Germany.

Microwave sensors have recently been introduced as high-temporal resolution sensors, which could be used in the contactless monitoring of artery pulsation and breathing. However, accurate and efficient signal processing methods are still required. In this paper, the matrix pencil method (MPM), as an efficient method with good frequency resolution, is applied to back-reflected microwave signals to extract vital signs. Read More

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Implementation of a Non-Thermal Atmospheric Pressure Plasma for Eradication of Plant Pathogens from a Surface of Economically Important Seeds.

Int J Mol Sci 2021 Aug 26;22(17). Epub 2021 Aug 26.

Laboratory of Plant Protection and Biotechnology, Intercollegiate Faculty of Biotechnology University of Gdansk and Medical University of Gdansk, University of Gdansk, 58 Abrahama, 80-307 Gdansk, Poland.

Plant pathogenic bacteria cause significant economic losses in the global food production sector. To secure an adequate amount of high-quality nutrition for the growing human population, novel approaches need to be undertaken to combat plant disease-causing agents. As the currently available methods to eliminate bacterial phytopathogens are scarce, we evaluated the effectiveness and mechanism of action of a non-thermal atmospheric pressure plasma (NTAPP). Read More

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An Examination to Explain the Mechanism of Employees' Environment-Specific Behavior through CSR and Work Engagement from the Perspective of Stewardship Theory.

Int J Environ Res Public Health 2021 Sep 5;18(17). Epub 2021 Sep 5.

Institute of Economic Sciences, Hungarian University of Agriculture and Life Sciences, 2100 Gödöllő, Hungary.

Corporate social responsibility (CSR) has emerged as an imperative for every sector globally. Yet, for a long time, the concept of CSR has been regarded from an organizational perspective. However, the importance of CSR in shaping the extra-role behavior of employees, such as their pro-environmental behavior (PEB-E), has been under-explored in the literature. Read More

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September 2021

Cognitive Remediation in Virtual Environments for Patients with Schizophrenia and Major Depressive Disorder: A Feasibility Study.

Int J Environ Res Public Health 2021 Aug 28;18(17). Epub 2021 Aug 28.

National Institute of Mental Health, 250 67 Klecany, Czech Republic.

Standard approaches to cognitive remediation can suffer from limited skill transferability to patients' life. Complex virtual environments (VEs) enable us to create ecologically valid remediation scenarios while preserving laboratory conditions. Nevertheless, the feasibility and efficacy of these programs in psychiatric patients are still unknown. Read More

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Unprecedented 2D GNR-CoB nanocomposite for detection and degradation of malachite green - A computational prediction of degradation pathway and toxicity.

Chemosphere 2021 Sep 3;287(Pt 2):132153. Epub 2021 Sep 3.

Grassland and Forage Division National Institute of Animal Science Rural Development Administration, Chungnam-do, 31000, South Korea.

In the present work, we have synthesized a novel 2D GNR-CoB composite and was applied it for electrochemical sensing and photocatalytic degradation of the malachite green (MG). The physicochemical properties of the 2D GNR-CoB were analyzed using X-ray diffraction, Transmission electron microscopy, Energy dispersive X-ray diffraction which depicts the morphological and crystalline nature of the prepared composite. The pencil graphite electrode modified with 2D GNR-CoB composite showed excellent electrochemical response for MG detection with a LOD of 1. Read More

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September 2021

Dose calculation accuracy in particle therapy: comparing carbon ions with protons.

Med Phys 2021 Sep 5. Epub 2021 Sep 5.

Department of Radiation Oncology, Medical University of Vienna, Vienna, 1090, Austria.

Purpose: This work presents the validation of an analytical pencil beam dose calculation algorithm in a commercial treatment planning system (TPS) for carbon ions by measurements of dose distributions in heterogeneous phantom geometries. Additionally, a comparison study of carbon ions versus protons is performed considering current best solutions in commercial treatment planning systems (TPS).

Methods: All treatment plans were optimized and calculated using the RayStation TPS (RaySearch, Sweden). Read More

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September 2021

Recommendations on screen time, sleep and physical activity: associations with academic achievement in Swiss adolescents.

Public Health 2021 Sep 1;198:211-217. Epub 2021 Sep 1.

Institute of Public Health, USI Università della Svizzera italiana, Via Buffi 13, 6900 Lugano Switzerland.

Objectives: This study aimed to investigate how meeting international recommendations for screen time (<2 h/day), moderate-to-vigorous physical activity (MVPA; at least 60 min/day) and sleep (8-10 h/night), as well as media multitasking (MMI) as a form of screen time, impact academic achievement in early adolescence.

Study Design: A prospective design was used, where self-report measures were collected during the spring semester and academic achievement at the end of the school year.

Methods: A total of 1208 grade 3 middle school students (M = 13. Read More

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September 2021

Acoustic-resolution photoacoustic microscope based on compact and low-cost delta configuration actuator.

Ultrasonics 2021 Aug 8;118:106549. Epub 2021 Aug 8.

Worcester Polytechnic Institute, Department of Robotics Engineering, 100 Institute Rd, Worcester 01609, United States; Worcester Polytechnic Institute, Department of Biomedical Engineering, 100 Institute Rd, Worcester 01609, United States; Worcester Polytechnic Institute, Department of Computer Science, 100 Institute Rd, Worcester 01609, United States. Electronic address:

The state-of-the-art configurations for acoustic-resolution photoacoustic (PA) microscope (AR-PAM) are large in size and expensive, hindering their democratization. While previous research on AR-PAMs introduced a low-cost light source to reduce the cost, few studies have investigated the possibility of optimizing the sensor actuation, particularly for the AR-PAM. Additionally, there is an unmet need to evaluate the image quality deterioration associated with the actuation inaccuracy. Read More

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Pencil impalement through mouth in a toddler.

Pediatr Int 2021 09;63(9):1140-1141

Geisinger Medical Center, Danville, PA, USA.

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September 2021

Pediatric unilateral spatial neglect: A systematic review.

J Pediatr Rehabil Med 2021 Aug 21. Epub 2021 Aug 21.

Department of Health Science and Research, College of Health Professions, Medical University of South Carolina, Charleston, SC, USA.

Purpose: Unilateral spatial neglect (USN), an inability to attend to one side of space or one's body, is commonly reported in adult stroke survivors and is associated with poor outcomes. USN has been reported in pediatric survivors of stroke, but its impact is unclear. The purpose of this systematic review was to summarize and evaluate the literature regarding USN in pediatric stroke survivors. Read More

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Reducing food insecurity and improving fruit and vegetable intake through a nutrition incentive program in Michigan, USA.

SSM Popul Health 2021 Sep 17;15:100898. Epub 2021 Aug 17.

Gretchen Swanson Center for Nutrition, 8401 West Dodge Road, Suite 100, Omaha, NE, 68114, USA.

Background: Nutrition incentive (NI) programs increase the purchase of fruits and vegetables (FVs) among low-income participants. Double Up Food Bucks (DUFB) is a robust statewide NI program in the United States. The purpose of this paper is to report findings from DUFB in Michigan describing the factors related to FV intake (FVI) and food insecurity among participants in a NI program. Read More

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September 2021

"One Note Higher": A Unique Pediatric Hand Fracture.

Clin Pract Cases Emerg Med 2021 May;5(2):270-272

Madigan Army Medical Center, Department of Emergency Medicine, Tacoma, Washington.

Case Presentation: An otherwise healthy, 12-year-old male presented to the emergency department after a fall down the stairs in which he landed on his right hand. Radiographs demonstrated a Salter-Harris II fracture at the base of the proximal phalanx of the fifth digit with ulnar deviation, also known as an "extra-octave" fracture. Orthopedic surgery was consulted and the fracture was reduced and placed in a short-arm cast. Read More

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A Novel and Accurate Palpation Method for Identification of the L4 Spinous Process: A Preliminary Study of Accuracy.

J Manipulative Physiol Ther 2021 Jun 21;44(5):398-407. Epub 2021 Aug 21.

Research Department, National University of Health Sciences, Lombard, Illinois. Electronic address:

Objective: The purpose of this study was to assess a novel method of lumbar spinous process (SP) palpation by using magnetic resonance imaging (MRI) high-signal marker reference standards for verification.

Methods: Clinicians (doctors of chiropractic) in this study used either: (1) the standard/traditional method of identifying the L4 SP using the supracristal plane (n = 14) or (2) a novel method that manually induced sacral motion to identify the L5 and then the L4 SP (n = 54). The clinicians, blinded to the results of each other, used a grease pencil to mark the location identified as the L4 SP. Read More

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Assessment of the Relative Biological Efficiency of Pencil Beam Scanning of Protons in Mice in Vivo.

Dokl Biochem Biophys 2021 Jul 23;499(1):215-219. Epub 2021 Aug 23.

Physical Technical Center, Lebedev Physical Institute, Russian Academy of Sciences, Protvino, Russia.

The effect of proton pencil beam scanning in the dose range of 4.5-15 Gy on the radiosensitivity of mice under irradiation in two regions of the Bragg curve was studied according to the criteria of 30-day survival, dynamics of death, and average lifespan of mice. The relative biological effectiveness (RBE) value of protons relative to X-ray radiation before and at the Bragg peak determined by the LD index was 0. Read More

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A Planning Comparison of IMRT vs. Pencil Beam Scanning for Deep Inspiration Breath Hold Lung Cancers.

Med Dosim 2021 Aug 20. Epub 2021 Aug 20.

Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

Deep inspiration breath hold (DIBH) has dosimetric advantages for lung cancer patients treated with external beam therapy, but is difficult for many patients to perform. Proton therapy permits sparing of the downstream organs at risk (OAR). We compared conventionally fractionated proton (p) and photon(x) plans on both free breathing (FB) and DIBH planning CTs to determine the effect of DIBH with proton therapy. Read More

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Engaging consumers in wise use of over-the-counter medications in Taiwan: Development and evaluation of a structured medication counseling approach.

Patient Educ Couns 2021 Aug 13. Epub 2021 Aug 13.

Graduate Institute of Clinical Pharmacy, College of Medicine, National Taiwan University, Taipei 100025, Taiwan; School of Pharmacy, College of Medicine, National Taiwan University, Taipei 100025, Taiwan. Electronic address:

Objective: To evaluate the impact of a tailored Symptom Allergy Indication Direction Self-care (SAIDS) counseling by pharmacists on consumers' correct understanding of over-the-counter (OTC) medication use.

Methods: This study used a time-based sampling of two independent cohorts at a single community pharmacy in Taiwan for two years beginning in December 2018. In the control cohort, participants received conventional counseling for the OTCs they selected. Read More

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Correlation of LET with MRI changes in brain and potential implications for normal tissue complication probability for meningioma patients treated with pencil beam scanning proton therapy.

Int J Radiat Oncol Biol Phys 2021 Aug 20. Epub 2021 Aug 20.

Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

Purpose: To investigate the correlation between imaging changes in brain normal tissue and the spatial distribution of linear energy transfer (LET) for a cohort of meningioma patients treated with scanned proton beams. Then, assuming imaging changes are induced by cell lethality, to study the correlation between normal tissue complication probability and LET.

Methods: MRI T2/FLAIR acquired at different intervals after proton radiation were co-registered with the planning CT images from 26 patients diagnosed with meningioma with abnormalities after proton radiotherapy. Read More

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Dosimetric Deviations of Bragg-Peak Position Shifts in Uniform Magnetic Fields for Magnetic Resonance Imaging-Guiding Proton Radiotherapy: A Monte Carlo Study.

Front Public Health 2021 3;9:641915. Epub 2021 Aug 3.

Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai, China.

To investigate dosimetric deviations in scanning protons for Bragg-peak position shifts, which were caused by proton spiral tracks in an ideal uniform field of magnetic resonance (MRI) imaging-guided proton radiotherapy (MRI-IGPRT). The FLUKA Monte-Carlo (MC) code was used to simulate the spiral tracks of protons penetrating water with initial energies of 70-270 MeV under the influence of field strength of 0.0-3. Read More

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September 2021

The Relationship Between SNS Usage and Disordered Eating Behaviors: A Meta-Analysis.

Front Psychol 2021 2;12:641919. Epub 2021 Aug 2.

School of Education, Shanghai International Studies University, Shanghai, China.

Social Networking Sites (SNSs) are common tools with which modern people share their lives and establish social relationships. However, some studies have found SNSs to be associated with eating disorders, although other have identified no connection between the two. To explore the interaction between SNSs and eating disorder behaviors, this study aimed to comprehensively synthesize previous studies using meta-analysis methods. Read More

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Inhibitory control in youth with Tourette's Disorder, attention-deficit/hyperactivity disorder and their combination and predictors of objective tic suppressibility.

Psychiatry Res 2021 Oct 5;304:114163. Epub 2021 Aug 5.

Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA 90095, United States.

The present study investigated inhibitory control deficits in Tourette's Disorder (TD)-only, Attention Deficit/Hyperactivity Disorder (ADHD)-only, and TD+ADHD and explored the degree to which measures of inhibitory control, and tic and ADHD severity predicted objective tic suppressibility. Participants were youth ages 9 to 14 (M = 11.15) with TD-only (n = 24), TD+ADHD (n = 19), ADHD-only (n = 139), and typically-developing controls (n = 59) drawn from a larger study. Read More

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October 2021

Retained anterior chamber graphite foreign body with delayed inflammation.

Am J Ophthalmol Case Rep 2021 Sep 4;23:101181. Epub 2021 Aug 4.

Department of Ophthalmology and Visual Sciences, Khoo Teck Puat Hospital, 90 Yishun Central, 768828, Singapore.

Purpose: To report a case of retained anterior chamber graphite foreign body with subsequent inflammation 20 years later.

Observations: A 29-year-old female who presented with first episode of acute blurring of vision and eye redness was noted to have a retained intraocular graphite foreign body in her anterior chamber. She recalled being accidently hit by a mechanical pencil 20 years ago. Read More

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September 2021

Burnout and Coping Perceptions of Volleyball Players Throughout an Annual Sport Season.

J Hum Kinet 2021 Jul 28;79:249-257. Epub 2021 Jul 28.

Sport Science Graduate Program, School of Physical Education, Physiotherapy and Occupational Therapy, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

Burnout is a psychological syndrome of reaction to chronic stress that occurs in athletes who feel exhausted by a sport activity that was previously pleasurable and enjoyable. One technique to prevent and control the syndrome is through coping, which is the ability to deal with stressful situations. In contrast to traditional cross-sectional approaches, this study aimed to investigate burnout and coping strategy characteristics over time and to analyze the relationship between burnout dimensions and coping strategies. Read More

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Evaluation of the fuel cell performances of TiO/PAN electrospun carbon-based electrodes.

Authors:
Sema Aslan

Turk J Chem 2021 30;45(3):661-672. Epub 2021 Jun 30.

Departmentof Chemistry, Faculty of Science, Muğla Sıtkı Koçman University, Muğla Turkey.

Electrocatalytic effect of the untreated and TiO+polyacrylonitrile (PAN) modified discarded battery coal (DBC) and pencil graphite electrodes (PGE) were evaluated in fuel cell (FC) applications. TiO+PAN solution is coated on PGE and DBC electrodes by electrospinning. According to the FESEM and EDS characterizations, TiO and PAN nanofibers are found to be approximately 40 and 240 nm in size. Read More

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Electrochemical investigation of the interaction of 2,4-D and double stranded DNA using pencil graphite electrodes.

Authors:
Gülşah Çongur

Turk J Chem 2021 30;45(3):600-615. Epub 2021 Jun 30.

Vocational School of Health Services, Bilecik Şeyh Edebali University, Bilecik Turkey.

2,4-dichlorophenoxyacetic acid (2,4-D) is an auxinic herbicide used to control broadleaf weeds. It is also a threatening factor for not only aquatic life but also human health due to its genotoxicity and endocrine disruptive property. Herein, the interaction between 2,4-D and double stranded DNA was investigated by using single-use pencil graphite electrodes (PGE) in combination with electrochemical techniques. Read More

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